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Clinical trials for General anaesthesia

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    220 result(s) found for: General anaesthesia. Displaying page 1 of 11.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2007-001979-10 Sponsor Protocol Number: ALMED-07-C3-007 Start Date*: 2008-05-05
    Sponsor Name:AIR LIQUIDE
    Full Title: AN INTERNATIONAL PHASE III RANDOMISED TRIAL COMPARING THE PROPOFOL CONSUMPTION DURING GENERAL ANAESTHESIA WITH XENON IN INSPIRATORY CONCENTRATIONS OF 50 % AND 70% AND TOTAL IV ANAESTHESIA ALONE I...
    Medical condition: general anaesthesia.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) DE (Completed) GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-003172-36 Sponsor Protocol Number: 29.06.2011 Start Date*: 2011-10-07
    Sponsor Name:Department of Anaesthesia, Tampere University Hospital
    Full Title: Arousal reaction during desflurane anaesthesia
    Medical condition: The patients who undergo abdominal surgeries (laparotomy or laparoscopy) under desflurane anaesthesia will be investigated.
    Disease: Version SOC Term Classification Code Term Level
    14.0 10042613 - Surgical and medical procedures 10018060 General anaesthesia PT
    14.0 10022891 - Investigations 10014275 EEG LLT
    14.0 10029205 - Nervous system disorders 10002091 Anaesthesia PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-003139-65 Sponsor Protocol Number: Start Date*: 2007-01-10
    Sponsor Name:Medway NHS Trust
    Full Title: The effect of clonidine on desflurane consumption using BIS monitoring.
    Medical condition: Depth of anaesthesia. Consumption of volatile anaesthetic agent.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10018060 General anaesthesia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-002803-81 Sponsor Protocol Number: TREX Start Date*: 2020-04-03
    Sponsor Name:IRCCS ISTITUTO GIANNINA GASLINI
    Full Title: Neurodevelopmental outcome after standard dose sevoflurane versus low-dose sevoflurane/dexmedetomidine/remifentanil anaesthesia in young children
    Medical condition: Children under the age of 2 years having surgery lasting at least 2 hours
    Disease: Version SOC Term Classification Code Term Level
    21.1 10042613 - Surgical and medical procedures 10018060 General anaesthesia PT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2019-000700-14 Sponsor Protocol Number: 2 Start Date*: 2019-07-08
    Sponsor Name:Medical University Graz
    Full Title: Pilot-Study comparing analgosedation concepts during placement of regional anaesthesia with either fentanyl, remifentanil, clonidine, EMLA-Patch or placebo in regard of patient's wellbeing, pain an...
    Medical condition: Patient with elective orthopedic surgery that will be administered a regional anaesthesia will be subject of the investigation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2011-000922-31 Sponsor Protocol Number: Cognitivefunction2011001 Start Date*: 2011-04-18
    Sponsor Name:Karolinska Institutet
    Full Title: Patients´ recovery day 0-3 after short-stay elective surgery – a pilot study comparing desflurane and propofol TCI as main anaesthetics.
    Medical condition: Patients undergoing elective general anaesthesia for breat surgery
    Disease: Version SOC Term Classification Code Term Level
    12.1 10002091 Anaesthesia LLT
    Population Age: Adults Gender: Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2005-001574-27 Sponsor Protocol Number: MR-2005\01 Start Date*: 2005-09-27
    Sponsor Name:AZIENDA OSPEDALIERA DI PERUGIA
    Full Title: Sevoflurane on cardiac surgery: vantage to use during CEC
    Medical condition: general anestetic inalathory also during CEC
    Disease: Version SOC Term Classification Code Term Level
    6.1 10018060 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-001534-34 Sponsor Protocol Number: 260319 Start Date*: 2022-03-11
    Sponsor Name:Odense University Hospital
    Full Title: Propofol and thiopental for intravenous induction in neonates: a dose finding study
    Medical condition: Any condition requiring general anesthesia.
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10018061 General anesthesia LLT
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2008-000537-22 Sponsor Protocol Number: 2007/11 Start Date*: 2008-07-21
    Sponsor Name:Hopital Foch
    Full Title: Anesthésie intraveineuse chez l’obèse : étude des posologies de propofol et de rémifentanil (étude multicentrique, prospective, ouverte comparant un groupe de patients obèses et un groupe de patien...
    Medical condition: general anaesthesia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10002323 Anesthesia general LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-004852-13 Sponsor Protocol Number: 2012001 Start Date*: 2014-06-24
    Sponsor Name:Anestesikliniken
    Full Title: Low fresh gas flow during elective general anaesthesia - A pilot study comparing Desflurane and Sevoflurane for anaesthetic controllability during wash-in and for haemodynamic control during elec...
    Medical condition: General anaesthesia time to onset - wash-in
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004346-10 Sponsor Protocol Number: N/A Start Date*: 2015-04-15
    Sponsor Name:Alder Hey Children's NHS Foundation Trust
    Full Title: Study to evaluate the optimal dose of remifentanil infusion(effective dose in 80% of patients) required to ensure apnoea (of 30 seconds duration) during magnetic resonance imaging of the heart unde...
    Medical condition: Study refers to the use of this medicine during anaesthesia given during the investigation of congenital heart disease.
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2015-002329-20 Sponsor Protocol Number: SR052015 Start Date*: 2015-08-11
    Sponsor Name:University Hospitals Leuven
    Full Title: Xenon as an adjuvant to sevoflurane anaesthesia in children younger than four, undergoing interventional or diagnostic cardiac catheterization: a pilot study.
    Medical condition: Xenon anesthesia in children undergoing cardiac catherization
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004865 10018061 General anesthesia LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2018-001252-35 Sponsor Protocol Number: DANA-2018-1. Start Date*: 2018-09-06
    Sponsor Name:Kirsten Møller
    Full Title: Neuroplasticity induced by general anaesthesia
    Medical condition: This trial investigates the effects of general anaesthesia on the helathy human brain. Thus, only healthy, young adults with no medical conditions will participate as volunteers in this study.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-001862-16 Sponsor Protocol Number: 1.7 Start Date*: 2013-06-05
    Sponsor Name:University Hospitals Bristol NHS Foundation Trust
    Full Title: Randomised controlled pilot study: Does intraoperative clonidine reduce the incidence of post-hospitalisation negative behaviour changes in children who are distressed during the induction of gener...
    Medical condition: Behaviour
    Disease: Version SOC Term Classification Code Term Level
    16.0 10037175 - Psychiatric disorders 10061422 Abnormal behaviour PT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2015-000051-24 Sponsor Protocol Number: RemiPedEntropy_v1.0 Start Date*: 2015-03-26
    Sponsor Name:Klaus Olkkola/University of Helsinki
    Full Title: The pharmacokinetics and –genomics of remifentanil, and its effects on the depth-of-anaesthesia monitors and the protein synthesis in children.
    Medical condition: otherwise healthy patients undergoing an operation necessitating general anaesthesia
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-000991-13 Sponsor Protocol Number: STH19610 Start Date*: Information not available in EudraCT
    Sponsor Name:Sheffield Teaching Hospitals NHS Foundation Trust
    Full Title: The MAGIC trial (Melatonin for Anxiety prior to General anaesthesia In Children): A Multicentre, Parallel Randomised Controlled Trial of Melatonin Versus Midazolam in the Premedication of Anxious C...
    Medical condition: Anxiety pre-general anaesthesia
    Disease: Version SOC Term Classification Code Term Level
    20.0 10037175 - Psychiatric disorders 10002869 Anxiety symptoms HLT
    20.1 10022117 - Injury, poisoning and procedural complications 10054711 Postoperative pain LLT
    20.1 10022117 - Injury, poisoning and procedural complications 10049989 Agitation postoperative PT
    20.0 10037175 - Psychiatric disorders 10002855 Anxiety PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2008-008193-31 Sponsor Protocol Number: 2008/44 Start Date*: Information not available in EudraCT
    Sponsor Name:Hopital Foch
    Full Title: Impact des facteurs chronologiques et démographiques sur les posologies per-opératoires des agents anesthésiques (Etude prospective multicentrique)
    Medical condition: general anesthesia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10002323 Anesthesia general LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-007179-26 Sponsor Protocol Number: 2008/41 Start Date*: 2009-02-13
    Sponsor Name:Hopital Foch
    Full Title: Evaluation de l’effet anesthésique de la dexmédétomidine dans une population d’opérés recevant une anesthésie totale intraveineuse en « boucle » guidée par l’index bispectral (Etude monocentrique, ...
    Medical condition: general anesthesia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10002323 Anesthesia general LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-012898-36 Sponsor Protocol Number: 2009/22 Start Date*: 2009-09-21
    Sponsor Name:Hopital Foch
    Full Title: Relation dose-effet du propofol : comparaison en double aveugle des différentes
    Medical condition: general anesthesia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10002323 Anesthesia general LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016094-16 Sponsor Protocol Number: AGO/2009/008 Start Date*: 2010-02-04
    Sponsor Name:University Hospital Ghent
    Full Title: Sevoflurane-Remifentanil interaction: Multiple response surfaces, validation of calibration stimuli, validation of the intraoperative isobole concept and investigating remifentanil induced opioid t...
    Medical condition: American Society of Anesthesia class I and II patients scheduled for surgery under general anesthesia.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10002323 Anesthesia general LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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