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Clinical trials for Glaucoma and ocular hypertension

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44412   clinical trials with a EudraCT protocol, of which   7421   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    144 result(s) found for: Glaucoma and ocular hypertension. Displaying page 1 of 8.
    1  2  3  4  5  6  7  8  Next»
    EudraCT Number: 2009-010101-36 Sponsor Protocol Number: Alcon SMA-08-22 Start Date*: 2009-09-21
    Sponsor Name:Alcon Laboratories, Inc.
    Full Title: The Efficacy and Safety of Adding the Brinzolamide/Timolol Maleate Fixed Combination (Azarga®) to Prostaglandin Monotherapy
    Medical condition: primary open-angle glaucoma ocular hypertension pigment dispersion glaucoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10035015 Pigmentary glaucoma LLT
    9.1 10030043 Ocular hypertension LLT
    9.1 10036719 Primary open angle glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-020746-98 Sponsor Protocol Number: 77557 Start Date*: 2010-11-01
    Sponsor Name:Santen Oy
    Full Title: An open-label phase IV study on the changes in ocular signs and symptoms in patients with ocular hypertension or open-angle glaucoma switched from preserved travoprost 0.004% eye drops to preservat...
    Medical condition: Patients diagnosed with Ocular Hypertension or Open-angle glaucoma (primary open-angle glaucoma [POAG] or capsular glaucoma)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10030856 Open-angle glaucoma LLT
    12.1 10030043 Ocular hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-021039-14 Sponsor Protocol Number: S001-2010 Start Date*: 2010-08-19
    Sponsor Name:Tampere University, Faculty of Medicine, Department of Ophthalmology
    Full Title: An open-label, phase IV, pilot study, to evaluate confocal microscopic findings of cornea, ocular signs and symptoms in patients with ocular hypertension or open-angle glaucoma switching from latan...
    Medical condition: Ocular Hypertension (OH) or Open-Angle Glaucoma (OAG); primary open-angle glaucoma [POAG] or capsular glaucoma.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10030043 Ocular hypertension LLT
    12.1 10030856 Open-angle glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-000161-13 Sponsor Protocol Number: RDG-10-272 Start Date*: 2012-03-07
    Sponsor Name:Alcon Research Ltd
    Full Title: Assessing the Efficacy and Tolerability of Changing to DuoTrav® (Travoprost 0.004%/Timolol 0.5% BAK-Free Fixed Combination), as Replacement Therapy in Patients Previously on Bimatoprost 0.03%/Timol...
    Medical condition: The study population must have been diagnosed with open angle glaucoma or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10030043 Ocular hypertension PT
    14.1 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-002131-18 Sponsor Protocol Number: 192024-093 Start Date*: 2016-12-21
    Sponsor Name:Allergan Limited
    Full Title: A Comparison of Bimatoprost SR to Selective Laser Trabeculoplasty in Patients with Open-Angle Glaucoma or Ocular Hypertension
    Medical condition: Open-angle Glaucoma and Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    20.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    20.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) DE (Completed) DK (Completed) PL (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2008-002760-34 Sponsor Protocol Number: C-08-10 Start Date*: 2008-10-02
    Sponsor Name:Alcon Research, Ltd.
    Full Title: A Multi-Center, Double-Masked Study of the Safety and Efficacy of Travoprost APS Compared to TRAVATAN® in Patients with Open-Angle Glaucoma or Ocular Hypertension
    Medical condition: Open-Angle Glaucoma or Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030348 Open angle glaucoma LLT
    9.1 10030043 Ocular hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2007-002501-45 Sponsor Protocol Number: EMD-06-02 Start Date*: 2008-03-14
    Sponsor Name:Alcon Laboratories Inc.
    Full Title: Phase IV randomised double masked clinical trial: Assessing morning versus evening dosing of a fixed dose combination of Travoprost 0.004% / Timolol Maleate 0.5% in patients with primary open angle...
    Medical condition: Open - angle glaucoma or ocular hypertension.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030348 Open angle glaucoma LLT
    9.1 10030043 Ocular hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-003083-31 Sponsor Protocol Number: Becro/OV/Brimo Start Date*: 2013-10-17
    Sponsor Name:OmniVision GmbH
    Full Title: Open, Observer-blind, two Parallel Group, Randomized, Multicentric Clinical Phase III Trial on the Comparison of Efficacy and Tolerability of a New Preservative-free Formulation of Brimonidine 2 mg...
    Medical condition: Open angle glaucoma or ocular hypertension.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10030043 Ocular hypertension PT
    14.1 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: View results
    EudraCT Number: 2008-006027-31 Sponsor Protocol Number: C-08-40 Start Date*: 2009-04-16
    Sponsor Name:Alcon Research, Ltd.
    Full Title: A multi-center, double-masked study of the safety and efficacy of Travoprost APS compared to TRAVATAN in patients with open-angle glaucoma or ocular hypertension.
    Medical condition: Open-angle glaucoma or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030348 Open angle glaucoma LLT
    9.1 10030043 Ocular hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) LV (Completed) FR (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2009-013178-42 Sponsor Protocol Number: C-09-032 Start Date*: 2009-07-31
    Sponsor Name:Alcon Research, Ltd.
    Full Title: A Twelve-Month Open-Label Safety Study of Polyquaternium-Preserved DuoTrav APS Dosed Once Daily in Patients with Open-Angle Glaucoma or Ocular Hypertension
    Medical condition: Open-Angle Glaucoma or Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    12.0 10030043 Ocular hypertension LLT
    12.0 10030348 Open angle glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) LV (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-022948-21 Sponsor Protocol Number: RDG-10-246 Start Date*: 2011-03-08
    Sponsor Name:Alcon Research, Ltd.
    Full Title: Eficacia y Seguridad de añadir Brinzolamida/Maleato de Timolol en combinación fija (Azarga ®) en pacientes con Hipertensión ocular o Glaucoma no controlados en Monoterapia de Prostaglandinas
    Medical condition: Hipertension ocular o glaucoma
    Disease: Version SOC Term Classification Code Term Level
    12.1 10030856 Open-angle glaucoma LLT
    12.1 10030043 Ocular hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2009-010604-29 Sponsor Protocol Number: C-09-007 Start Date*: 2009-06-30
    Sponsor Name:Alcon Research, Ltd.
    Full Title: An evaluation of the Ocular Surface Health in Subjects Using DuoTrav APS Eye Drops Solution Versus XALACOM® EYE Drops Solution
    Medical condition: glaucoma/dry eye
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030348 Open angle glaucoma LLT
    9.1 10018307 Glaucoma and ocular hypertension HLGT
    9.1 10030043 Ocular hypertension LLT
    9.1 10013774 Dry eye LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) HU (Prematurely Ended) NL (Prematurely Ended) IT (Prematurely Ended) BE (Completed) PT (Prematurely Ended) AT (Prematurely Ended) GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-003617-42 Sponsor Protocol Number: BP25466 Start Date*: 2011-12-14
    Sponsor Name:F. Hoffmann-La Roche Ltd.
    Full Title: An adaptive, multi-center, randomized, investigator-masked, subject-masked, multiple-dose, placebo-controlled, parallel study to investigate efficacy, safety, tolerability and pharmacokinetics of...
    Medical condition: Primary open angle glaucoma or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    14.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) CZ (Prematurely Ended) BG (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-021973-35 Sponsor Protocol Number: RDG-10-243 Start Date*: 2010-10-14
    Sponsor Name:Alcon Research, Ltd.
    Full Title: Assessing the Safety and Efficacy of Changing to DuoTrav® (Travoprost 0.004%/Timolol 0.5% Fixed Combination), as Replacement Therapy in Patients Uncontrolled on Bimatoprost 0.03%/Timolol 0.5% Thera...
    Medical condition: Open-angle glaucoma, ocular hypertension or pigment dispersion glaucoma
    Disease: Version SOC Term Classification Code Term Level
    12.1 10030856 Open-angle glaucoma LLT
    12.1 10030043 Ocular hypertension LLT
    12.1 10052134 Pigment dispersion syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2009-011036-36 Sponsor Protocol Number: C-01-78 Start Date*: 2009-05-07
    Sponsor Name:Alcon Research, Ltd.
    Full Title: Estudio multicéntrico de la pigmentación en la red trabecular después de dos años de tratamiento con TRAVATAN 0,004% solución oftálmica. A multicenter study of the pigmentation in the trabecular me...
    Medical condition: Glaucoma de angulo abierto o hiperstensión ocular. Open-angle glaucoma or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030348 Open angle glaucoma LLT
    9.1 10030043 Ocular hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-022984-36 Sponsor Protocol Number: 201051 Start Date*: Information not available in EudraCT
    Sponsor Name:Santen Oy
    Full Title: A phase III, randomized, double-masked 6-month clinical study to compare the efficacy and safety of the preservative-free fixed dose combination of tafluprost 0.0015% and timolol 0.5% eye drops to ...
    Medical condition: Patients diagnosed with ocular hypertension or open-angle glaucoma (primary open-angle glaucoma [POAG], capsular glaucoma or pigmentary glaucoma).
    Disease: Version SOC Term Classification Code Term Level
    12.1 10030043 Ocular hypertension LLT
    12.1 10036719 Primary open angle glaucoma LLT
    12.1 10035015 Pigmentary glaucoma LLT
    12.1 10037118 Pseudoexfoliation glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) LV (Completed) CZ (Completed) ES (Completed) PT (Completed) AT (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2010-022965-82 Sponsor Protocol Number: 201050 Start Date*: 2010-12-22
    Sponsor Name:Santen Oy
    Full Title: A phase III, randomized, double-masked 6-month clinical study to compare the efficacy and safety of the preservative-free fixed-dose combination of tafluprost 0.0015% and timolol 0.5% eye drops to ...
    Medical condition: Ocular hypertension and POAG, capsular glaucoma and pigmentary glaucoma
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10035015 Pigmentary glaucoma PT
    14.1 10015919 - Eye disorders 10030043 Ocular hypertension PT
    14.1 10015919 - Eye disorders 10036719 Primary open angle glaucoma LLT
    14.1 10015919 - Eye disorders 10037118 Pseudoexfoliation glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) GB (Completed) DE (Completed) EE (Completed) NL (Completed) PL (Completed) IT (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2010-024272-26 Sponsor Protocol Number: GLC-05-10 Start Date*: 2011-04-14
    Sponsor Name:IRCCS- FONDAZIONE G.B. BIETTI PER LO STUDIO E LA RICERCA IN OFTALMOLOGIA-ONLUS
    Full Title: Comparison of the effects of Bimatoprost 0.01% and Timolol 0.5% on circadian intraocular pressure
    Medical condition: glaucoma and ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2015-000736-15 Sponsor Protocol Number: GLH694-P001 Start Date*: 2015-09-14
    Sponsor Name:Alcon Research, Ltd.
    Full Title: Additive Effect of Twice Daily Brinzolamide 1% /Brimonidine 0.2% Fixed Dose Combination as an Adjunctive Therapy to a Prostaglandin Analogue
    Medical condition: Ocular Hypertension Open-angle Glaucoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    20.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Completed) GB (Completed) FR (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2016-000176-20 Sponsor Protocol Number: GLJ576-P001 Start Date*: 2016-05-29
    Sponsor Name:Alcon Research Ltd
    Full Title: Safety and Efficacy with Twice Daily Brinzolamide 1% / Brimonidine 0.2% (SIMBRINZA) as an Adjunctive Therapy to Travoprost 0.004% / Timolol 0.5% (DUOTRAV)
    Medical condition: Ocular Hypertension Open-angle Glaucoma
    Disease: Version SOC Term Classification Code Term Level
    19.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    19.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended) BE (Completed) GB (Prematurely Ended) DE (Completed) GR (Completed) FR (Completed) NL (Prematurely Ended)
    Trial results: View results
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