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Clinical trials for Heliox

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    15 result(s) found for: Heliox. Displaying page 1 of 1.
    EudraCT Number: 2005-002585-11 Sponsor Protocol Number: AL001 Start Date*: 2005-10-10
    Sponsor Name:Imperial College
    Full Title: CPAP;Heliox Effects on Stability and Therapeutics
    Medical condition: Respiratory Distress requiring CPAP Examples: Bronchilitis, post-exturbation, Upper Airway Obstruction...
    Disease:
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-005289-37 Sponsor Protocol Number: 3_1_6 Start Date*: 2007-05-16
    Sponsor Name:University Witten/Herdecke
    Full Title: Anwendung von HELIOX an einem Modell der oberen Atemwegsobstruktion
    Medical condition: A model of upper airway obstruction will be used to test the hypothesis that HELIOX 21 when additional oxygen is added (which is a common clinical situation) still can reduce the work of breathing....
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-000832-42 Sponsor Protocol Number: n/a Start Date*: 2008-11-05
    Sponsor Name:East Kent Hospital Trust
    Full Title: Effectiveness of Heliox in Hypercapnic Respiratory Failure
    Medical condition: Hypercapnic Respiratory Failure due to excerbation of Chronic Obstructive Pulmonary Disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010953 COPD exacerbation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-004959-50 Sponsor Protocol Number: Heliox-AP Start Date*: 2016-05-29
    Sponsor Name:S.E. Carburos Metálicos S.A. grupo Air Products
    Full Title: HELIOX-DRIVEN BETA2-AGONISTS NEBULIZATION FOR CHILDREN WITH MODERATE TO SEVERE ACUTE ASTHMA: A RANDOMIZED CONTROLLED TRIAL
    Medical condition: Moderate to severe exacerbations of asthma
    Disease: Version SOC Term Classification Code Term Level
    19.0 10038738 - Respiratory, thoracic and mediastinal disorders 10064823 Asthmatic crisis PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2008-008274-31 Sponsor Protocol Number: ARKFTN-1/2008 Start Date*: 2009-06-12
    Sponsor Name:Fakultní Thomayerova nemocnice s poliklinikou
    Full Title: Establishing a new method of heliox administration in the management of acute exacerbation of chronic obstructive lung disease
    Medical condition: Těžká exacerbace chronické obstrukční plicní nemoci
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-000053-62 Sponsor Protocol Number: sph/itu/0001 Start Date*: 2007-06-18
    Sponsor Name:Ashford & St. Peter's Hospitals NHS Trust
    Full Title: The effects of helium-oxygen gas mixture (Heliox) on airway pressures in mechanically ventilated adult patients with acute lung injury
    Medical condition: Acute lung injury
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038696 Respiratory failure (excl neonatal) LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2008-005660-13 Sponsor Protocol Number: He-08-01 Start Date*: 2008-12-11
    Sponsor Name:BOC Ltd.
    Full Title: COPD exacerbation - Heliox Therapy - Assessment Heliox vs. Medical Air in Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Pilot Randomised Controlled Trial
    Medical condition: Chronic Obstructive Pulmonary Disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010953 COPD exacerbation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-000992-12 Sponsor Protocol Number: HIPP-CABG Start Date*: 2008-03-27
    Sponsor Name:Academic Medical Center
    Full Title: Organ protection by noble gases – A clinical study to investigate Helium induced Pre- and Postconditioning in patients undergoing coronary artery bypass surgery (HIPP-CABG).
    Medical condition: patients undergoing coronary artery bypass surgery, helium induced pre- and postconditioning
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-003007-36 Sponsor Protocol Number: HP002A Start Date*: 2006-08-02
    Sponsor Name:Imperial College London [...]
    1. Imperial College London
    2. BOC Ltd.
    Full Title: B.R.E.A.T.H.E. Bronchiolitis RCT: Emergency Assisted Therapy with Heliox - an Evaluation. A Prospective, Double-Blinded, Randomised, Controlled Clinical Trial to assess the effect of helium-oxygen ...
    Medical condition: Bronchiolitis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10006448 Bronchiolitis LLT
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-003612-30 Sponsor Protocol Number: 0904HELIOX Start Date*: 2005-11-23
    Sponsor Name:Barts and the London NHS Trust
    Full Title: A comparison of Helium-oxygen mixture (Heliox) with an oxygen-air mixture in reducing the work of breathing during weaning from mechanical ventilation.
    Medical condition: Patients admitted to the intensive care unit who are in the recovery phase of their illness and are weaning from mechanical ventilation.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-017499-26 Sponsor Protocol Number: Heres Start Date*: 2010-03-16
    Sponsor Name:Academical Medical Center, University of Amsterdam
    Full Title: The use of Helium after Resuscitation: a safety and feasibility study
    Medical condition: Persistent coma after cardiac arrest.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10038749 Resuscitation LLT
    12.1 10068191 Postresuscitation encephalopathy LLT
    12.1 10038749 Resuscitation PT
    12.1 10068191 Postresuscitation encephalopathy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016596-30 Sponsor Protocol Number: FIBHGM-ECNC003-2010(FIBHGM-10-01) Start Date*: 2010-08-25
    Sponsor Name:Fundación para la Investigación Biomédica del Hospital Gregorio Marañón
    Full Title: CORTICOIDES PARA LA PREVENCIÓN DE LAS COMPLICACIONES DE LA VIA AÉREA POSTEXTUBACIÓN EN NIÑOS CRÍTICOS
    Medical condition: necesidad de intubación por cualquier patología
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-010621-39 Sponsor Protocol Number: Start Date*: 2009-06-30
    Sponsor Name:Comité Départemental d’Hygiène Social
    Full Title: Apport de l’Hélium dans le réentraînement à l’effort des patients atteints de broncho-pneumopathie chronique obstructive sévère. Etude prospective en double aveugle randomisée. Mélange hélium-oxygè...
    Medical condition: réentraînement à l’effort des patients atteints de bronchopneumopathies obstructives sévères
    Disease: Version SOC Term Classification Code Term Level
    9.1 10009033 Chronic obstructive pulmonary disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017014-80 Sponsor Protocol Number: Helium_and_the_coronary_circulation Start Date*: 2010-02-22
    Sponsor Name:Academical Medical Center, University of Amsterdam
    Full Title: The effect of helium inhalation on the coronary circulation and vessel diameter
    Medical condition: Coronary artery disease
    Disease: Version SOC Term Classification Code Term Level
    12.0 10011078 Coronary artery disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-022393-13 Sponsor Protocol Number: Helium-MI Start Date*: 2010-11-24
    Sponsor Name:Academical Medical Center, University of Amsterdam
    Full Title: Does helium protect the heart against ischaemia-reperfusion damage in patients with acute myocardial infarction?
    Medical condition: Acute myocardial infarction
    Disease: Version SOC Term Classification Code Term Level
    12.1 10000891 Acute myocardial infarction LLT
    12.1 10051624 Myocardial reperfusion injury LLT
    12.1 10063837 Reperfusion injury LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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