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Clinical trials for Histamine

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    198 result(s) found for: Histamine. Displaying page 1 of 10.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2015-004436-34 Sponsor Protocol Number: CSOM230Y2201 Start Date*: 2017-02-06
    Sponsor Name:Novartis Pharma AG
    Full Title: A Multicenter, Placebo-Controlled, Single Dose Study in Acute Episodic and Chronic Cluster Headache to Evaluate the Safety and Efficacy of SOM230 subcutaneous (s.c.)
    Medical condition: Cluster headache
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10059133 Cluster headache PT
    20.0 10029205 - Nervous system disorders 10009698 Cluster headaches LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-004999-36 Sponsor Protocol Number: BCBe/04/FRO-CLU/001 Start Date*: 2006-11-06
    Sponsor Name:Berlin-Chemie AG
    Full Title: Effects of Frovatriptan as Prophylactic Treatment of Cluster Headache, a Multi-Center, Placebo Controlled, Randomized, Double-Blind Prospective Phase III Parallel-Group Trial Comparing Frovatriptan...
    Medical condition: Episodic cluster headache
    Disease: Version SOC Term Classification Code Term Level
    8.0 10009698 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-019058-42 Sponsor Protocol Number: LITIO-SUM-FC-002 Start Date*: 2010-05-26
    Sponsor Name:AZIENDA OSPEDALIERO UNIVERSITARIA DI CAGLIARI
    Full Title: Safety of sumatriptan in combination with lithium for treatment of cluster headache, Pilot Study,Phase II
    Medical condition: Cluster Headache
    Disease: Version SOC Term Classification Code Term Level
    12.1 10019232 Headaches cluster LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-000248-91 Sponsor Protocol Number: BTACH2012 Start Date*: 2013-01-08
    Sponsor Name:Institutt for nevromedisin, NTNU
    Full Title: Endoscopic block of the sphenopalatine ganglion with botulinum toxin in intractable cluster headache. Safety issues.
    Medical condition: Pharmacological refractory cluster headache with durations of periods of attacks normally more than 2 months
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004852 10009698 Cluster headaches LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: View results
    EudraCT Number: 2011-006204-13 Sponsor Protocol Number: PredCH Start Date*: 2013-01-17
    Sponsor Name:University of Duisburg-Essen
    Full Title: Efficacy and safety of oral prednisone as add-on therapy in the prophylactic treatment of episodic cluster headache: a randomized, placebo controlled parallel study.
    Medical condition: Episodic Cluster Headache (ECH)
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004852 10009698 Cluster headaches LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-004399-16 Sponsor Protocol Number: CHERUB01 Start Date*: 2021-04-28
    Sponsor Name:Charité - Universitätsmedizin Berlin
    Full Title: Efficacy of erenumab in chronic cluster headache: A 10-week double-blind, randomized, placebo-controlled, multicentric trial
    Medical condition: chronic cluster headache
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004852 10009698 Cluster headaches LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-000149-22 Sponsor Protocol Number: I5Q-MC-CGAL Start Date*: 2015-07-02
    Sponsor Name:Eli Lilly and Company
    Full Title: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study of LY2951742 in Patients with Episodic Cluster Headache
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10009698 Cluster headaches LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed) DK (Completed) BE (Completed) FI (Completed) ES (Completed) NL (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2014-005429-11 Sponsor Protocol Number: I5Q-MC-CGAM Start Date*: 2015-07-14
    Sponsor Name:Eli Lilly and Company
    Full Title: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study of LY2951742 with a Long-Term Open-Label Extension in Patients with Chronic Cluster Headache
    Medical condition: Chronic Cluster Headache
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10009698 Cluster headaches LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) ES (Completed) DK (Completed) FI (Completed) BE (Completed) FR (Completed) NL (Completed) GR (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-001291-12 Sponsor Protocol Number: SPON CU 085 Start Date*: 2005-04-27
    Sponsor Name:Cardiff University
    Full Title: Histamine Release and Implications of H1- and H2- Blockade in Adult Cardiac Surgery - A Randomised Controlled Study
    Medical condition: During cardiac surgery involving the use of cardiopulmonary bypass histamine is released in the blood. Histamine release has been related to an increased incidence of perioperative dysrhythmias and...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-005234-21 Sponsor Protocol Number: I5Q-MC-CGAR Start Date*: 2016-10-13
    Sponsor Name:Eli Lilly and Company
    Full Title: A Phase 3b Multicenter, Single-Arm, Open-Label Safety Study of LY2951742 (galcanezumab) in Patients with Episodic or Chronic Cluster Headache
    Medical condition: Episodic Cluster Headache, Chronic Cluster Headache
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10059133 Cluster headache PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) BE (Completed) FI (Completed) ES (Completed) DK (Completed) NL (Completed) GR (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-003729-62 Sponsor Protocol Number: R-Verapamil-001 Start Date*: 2013-01-16
    Sponsor Name:CENTER LABORATORIES, INC
    Full Title: A Randomized, Placebo-Controlled, Double-Blind, Parallel-Group, Phase 2 Study to Evaluate the Safety and Efficacy of R-Verapamil in the Prophylaxis of Episodic Cluster Headache
    Medical condition: Episodic Cluster Headache
    Disease: Version SOC Term Classification Code Term Level
    15.0 10029205 - Nervous system disorders 10059133 Cluster headache PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2020-001968-28 Sponsor Protocol Number: 19385A Start Date*: 2022-02-24
    Sponsor Name:H. Lundbeck A/S
    Full Title: Interventional, open-label, fixed-dose multiple administration study to evaluate long-term treatment with eptinezumab in patients with chronic cluster headache
    Medical condition: Chronic cluster headache
    Disease: Version SOC Term Classification Code Term Level
    24.0 10029205 - Nervous system disorders 10059133 Cluster headache PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) DK (Completed) NL (Completed) FI (Completed) ES (Ongoing) IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-003385-34 Sponsor Protocol Number: CRU.LUMC.001 Start Date*: 2006-11-23
    Sponsor Name:Boehringer Ingelheim Pharma GmbH & Co. KG
    Full Title: The effect of tiotropium-bromide on deep inspiration-induced bronchodilation and airway responsiveness in asthma.
    Medical condition: 24 patients with mild persistent asthma will participate in the study. All patients will be allergic to one or more airborne allergens, hyperresponsive to histamine (PC20 < 8 mg/ml) and have a norm...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10003638 Atopic asthma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-005368-24 Sponsor Protocol Number: T502-SSP-007 Start Date*: 2014-06-30
    Sponsor Name:INMUNOTEK, S.L.
    Full Title: Extract allergen from Betula verrucosa. Test sensitivity and specificity of diagnostic in prick test preparation.
    Medical condition: Allergy to Betula verrucosa
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004870 10066093 Birch pollen allergy LLT
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2005-001880-68 Sponsor Protocol Number: 1001-PR-PRI-133 Start Date*: 2005-09-23
    Sponsor Name:LETI Pharma GmbH
    Full Title: Standardization of Latex allergenic extract. Determination of biological activity in HEP units
    Medical condition: The objective of the study is to know the biologic activity of the Latex reference extract (IHRP) in HEP units. The HEP value will be the reference of every other diagnostic or treatment preparations.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2019-002644-24 Sponsor Protocol Number: DIA-STA--11-01-19 Start Date*: 2020-03-11
    Sponsor Name:Diater, Laboratorio de Diagnóstico y Aplicaciones Terapéuticas S.A.
    Full Title: Biological standarization of allergic extracts of will grasses: Phleum pratense, Lolium perenne, Poa pratensis y Dactylis glomerata and its mixture to determinate their biological activity, the In ...
    Medical condition: Biological standarization for allergenic extracts in patients with hipersensibility to extract
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021428 - Immune system disorders 10001708 Allergic conditions HLGT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2013-003270-28 Sponsor Protocol Number: VB-02-DFLOP Start Date*: 2014-01-27
    Sponsor Name:Instituto de Inmunología y Alergia INMUNAL S.A..U.
    Full Title: Biological standardization of allergenic extracts of Dermatophagoides farinae and Lolium perenne. Open label. Single Center. Phase II Study.
    Medical condition: Biological standardization for allergenic extracts in patients with hipersensibility to extracts.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021428 - Immune system disorders 10001708 Allergic conditions HLGT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-019344-39 Sponsor Protocol Number: BUCUM1 Start Date*: 2010-08-09
    Sponsor Name:Charité Universitätsmedizin Berlin
    Full Title: Double-blind, triple cross-over, placebo-controlled study to assess the efficacy, mechanisms, and safety of treatment with bilastine 20 mg, 40 mg and 80 mg in cold contact urticaria (CCU) Compound:...
    Medical condition: Cold contact urticaria
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2014-004874-41 Sponsor Protocol Number: NMDSG14A Start Date*: 2016-07-25
    Sponsor Name:Nordic MDS study group
    Full Title: Safety, Efficacy and Immune Response of Histamine Dihydrochloride and Low-dose Interleukin-2 in Chronic Myelomonocytic Leukemia (CMML)
    Medical condition: Chronic myelomonocytic leukemia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-002835-27 Sponsor Protocol Number: DRP-05-12 Start Date*: 2012-09-07
    Sponsor Name:Dr. Ritsert Pharma
    Full Title: Double-blind, randomized clinical study to determine the efficacy of Anestherit® 10% on histamine-induced pruritus and UVB-light induced slight sunburn in healthy subjects.
    Medical condition: Histamine-induced pruritus UVB-light-induced slight sunburn
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: AT (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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