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Clinical trials for Hyaluronic acid

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    52 result(s) found for: Hyaluronic acid. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2019-001151-40 Sponsor Protocol Number: CTU148N Start Date*: 2019-07-09
    Sponsor Name:RIEMSER Pharma GmbH
    Full Title: Phase II pilot study: To determine an effective and tolerable dose of Hylase® "Dessau" (bovine hyaluronidase) in the treatment of hyaluronic acid filler overshoots by injection into defined areas o...
    Medical condition: In this study, healthy subjects get an artificial over-injection with Hyaluron acid filler on the back of the hands. To demonstrate the effectiveness of hylase® "Dessau" as an antidote for hyaluro...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-004120-21 Sponsor Protocol Number: COX1985 Start Date*: 2016-01-22
    Sponsor Name:FUNDACIÓN PÚBLICA ANDALUZA PROGRESO Y SALUD
    Full Title: CLINICAL TRIAL RANDOMIZED, DOUBLE-BLIND CONTROLLED, PHASE III, TO EVALUATE THE USE OF PLATELET RICH PLASMA IN FRONT HYALURONIC ACID IN COXARTHROSIS.
    Medical condition: coxarthrosis
    Disease: Version SOC Term Classification Code Term Level
    18.0 10022891 - Investigations 10058417 Hyaluronic acid PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2010-020057-13 Sponsor Protocol Number: 034-002 Start Date*: 2010-06-11
    Sponsor Name:Dermatologikum Hamburg
    Full Title: Proof-of-concept-study to Evaluate the Efficacy and Tolerability of Repeated Versus Single Treatment with Botulinum-Toxin (Vistabel®) Treatment in Combination with a Hyaluronic Acid (Juvederm-Ultra...
    Medical condition: moderate to severe glabellar frown lines
    Disease: Version SOC Term Classification Code Term Level
    12.1 10052609 Glabellar frown lines LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-000906-36 Sponsor Protocol Number: GEB-IAL-2014-01 Start Date*: 2014-12-09
    Sponsor Name:Laboratorios Gebro Pharma S.A.
    Full Title: Randomized, parallel, multicenter, phase IV clinical trial to assess the efficacy of hyaluronic acid/chondroitin sulfate versus fosfomycin trometamol in recurrent urinary tract infection prevention.
    Medical condition: Recurrent urinary tract infections
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-019019-39 Sponsor Protocol Number: 02.2010 Start Date*: 2010-08-31
    Sponsor Name:Erasmus MC
    Full Title: 'Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) as an outcome measure to evaluate the effectiveness of intra-articular hyaluronic acid for knee osteoarthritis’
    Medical condition: Osteoarthritis of the knee
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-002331-34 Sponsor Protocol Number: ALOFEC-2019 Start Date*: 2022-11-08
    Sponsor Name:FIMABIS
    Full Title: A multicenter, randomized, double-blind Phase IIb study to evaluate the safety and efficacy of the intralesional administration of two doses of expanded allogeneic adipose tissue adult stem mesench...
    Medical condition: Fecal incontinence
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004856 10016296 Fecal incontinence LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-004117-40 Sponsor Protocol Number: Q03.13.01 Start Date*: 2013-12-19
    Sponsor Name:Fidia Farmaceutici SpA
    Full Title: Randomized, controlled, double-blinded clinical trial, with open-label extension on the efficacy of ultrasound guided injection of hyaluronic acid (500-730 KDa) (HYALGAN®) versus saline solution in...
    Medical condition: Achilles tendinopathy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-002446-21 Sponsor Protocol Number: ARTROCELL Start Date*: 2020-04-20
    Sponsor Name:IBSAL (Instituto de Investigación Biomédica de Salamanca)
    Full Title: Phase III, multicentre, randomized, open clinical trial comparing treatment with allogenic mesenchymal cells against autologous mesenchymal cells and against active control with hyaluronic acid in ...
    Medical condition: Knee osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-001203-50 Sponsor Protocol Number: 05DF1211 Start Date*: 2014-07-31
    Sponsor Name:Q-med AB
    Full Title: An evaluator-blinded multi-center study of combined treatment with Azzalure, Restylane/Emervel filler and Restylane skinbooster as compared to single treatment with either Azzalure alone or Restyla...
    Medical condition: Subjects with the intention to undergo facial aesthetic treatment and who are likely to benefit from a combination of injection treatments
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2014-001202-17 Sponsor Protocol Number: 05PDF1401 Start Date*: 2014-07-31
    Sponsor Name:Q-med AB
    Full Title: An evaluator-blinded multi-center study of combined treatment with Azzalure/Dysport, Restylane/Emervel filler and Restylane skinbooster as compared to single treatment with either Azzalure/Dysport ...
    Medical condition: Subjects with the intention to undergo facial aesthetic treatment and who are likely to benefit from a combination of injection treatments
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2011-003207-37 Sponsor Protocol Number: 750/11 Start Date*: 2012-01-22
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: COMPARISON BETWEEN INTRA-ARTICULAR INJECTION OF CORTICOSTEROIDS AND INTRA-ARTICULAR INJECTION OF HYALURONIC ACID IN THE TREATMENT OF ROTATOR CUFF TENDINOPATHY. A PROSPECTIVE CLINICAL TRIAL.
    Medical condition: ROTATOR CUFF TENDINOPATHY
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10039227 Rotator cuff syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-002425-21 Sponsor Protocol Number: 11054 Start Date*: 2012-02-10
    Sponsor Name:University of Nottingham
    Full Title: Efficacy of Dehydroepiandrosterone to overcome the effect of ovarian aging
    Medical condition: Women having low ovarian reserve undergoing IVF/ICSI treatment
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-020513-87 Sponsor Protocol Number: Q03-09-01 Start Date*: 2010-09-02
    Sponsor Name:FIDIA
    Full Title: A randomized, placebo-controlled, double-blind study on the intensity and duration of efficacy of sodium hyaluronate therapy (500-730 KDa) (HYALGAN) in the conservative treatment of Achilles tendin...
    Medical condition: Achilles tendinopathy.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000433 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2021-006801-31 Sponsor Protocol Number: 01-INSULINAOJOSECO-2021 Start Date*: 2022-07-04
    Sponsor Name:Barbara Burgos-Blasco
    Full Title: RANDOMIZED PARALLEL CLINICAL TRIAL TO DETERMINE THE EFFECTIVENESS AND SAFETY OF TOPICAL INSULIN IN THE TREATMENT OF DRY EYE IN PATIENTS WITH DRY EYE
    Medical condition: Dry eye disease
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-002298-20 Sponsor Protocol Number: CHD046-17 Start Date*: 2018-01-23
    Sponsor Name:Centre Hospitalier Départemental Vendée
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10062893 Rhizarthrosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2009-012442-23 Sponsor Protocol Number: Start Date*: 2009-11-18
    Sponsor Name:Dorset County Hospital NHS foundation trust
    Full Title: Intraarticular injections for hip osteoarthritis: Steroid versus Hyaluronic acid: randomised controlled trial
    Medical condition: Osteoarthritis of hip joint
    Disease: Version SOC Term Classification Code Term Level
    9.0 10031161 osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-002088-33 Sponsor Protocol Number: PER-DIC-16-001 Start Date*: 2016-09-01
    Sponsor Name:FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS UNIVERSITA' CATTOLICA DEL SACRO CUORE
    Full Title: Impact and Costs of Health Care Education, Phone Reminders and enhanced follow-up intervention on Prescription adherence, Treatment Satisfaction and Effectiveness in patients with Multiple Actinic ...
    Medical condition: Multiple Actinic Keratosis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10040785 - Skin and subcutaneous tissue disorders 10000614 Actinic keratosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-005000-17 Sponsor Protocol Number: JU-BioMiStem-01 Start Date*: 2021-09-20
    Sponsor Name:Jagiellonian University
    Full Title: A Randomized, Double Blind, Two Arms, Controlled Phase I/II Safety and Efficacy Study on MesoCellA-Ortho Tissue Engineered Product Intraarticularly Administrated in Adult Patients with Osteoarthrosis
    Medical condition: articular knee diseases
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-024225-20 Sponsor Protocol Number: 301110_PALANCE Start Date*: 2014-08-22
    Sponsor Name:University Hospital Munich, Germany
    Full Title: The impact of phosphate balanced cristalloid infusion on acid-base homeostastis
    Medical condition: This study aims to investigate a new crystalloid fluid therapy regime for the perioperative setting providing stable fluid and acid-base homeostasis in the patient.
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2021-001341-12 Sponsor Protocol Number: UV/AP/21 Start Date*: 2023-04-14
    Sponsor Name:Red Andaluza de Diseño y Traslación en Terapias Avanzadas - Fundación Pública Andaluza Progreso y Salud M.P.
    Full Title: Phase I-II, Multicenter, Randomized, Controlled, Proof of Concept Clinical Trial to determine feasibility, safety and efficacy of the use of Allogenic adipose-derived adult mesenchymal stem cells e...
    Medical condition: Venous ulcer
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004858 10047259 Venous ulcer NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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