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Clinical trials for Knee Degenerative Disease

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    The EU Clinical Trials Register currently displays   44343   clinical trials with a EudraCT protocol, of which   7372   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    49 result(s) found for: Knee Degenerative Disease. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2013-003467-60 Sponsor Protocol Number: M13-741 Start Date*: 2014-06-11
    Sponsor Name:AbbVie Deutschland GmbH & Co. KG
    Full Title: A Phase 2a Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of ABT-981 in Patients with Knee Osteoarthritis
    Medical condition: Adult male and female patients with mild to moderate, symptomatic, radiographic and inflammatory osteoarthritis of the knee
    Disease: Version SOC Term Classification Code Term Level
    18.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) GB (Completed) NL (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2011-000692-14 Sponsor Protocol Number: HKO-22112010 Start Date*: 2011-11-03
    Sponsor Name:Hannu Kokki
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10067624 Knee arthritis LLT
    14.0 10022117 - Injury, poisoning and procedural complications 10036284 Post-operative hip pain LLT
    14.0 10042613 - Surgical and medical procedures 10023479 Knee total replacement LLT
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10065955 Hip arthrosis LLT
    14.0 10042613 - Surgical and medical procedures 10003397 Arthroplasty of hip LLT
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10031174 Osteoarthrosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-002035-15 Sponsor Protocol Number: 0 Start Date*: 2016-05-20
    Sponsor Name:Helsinki University Central Hospital
    Full Title: Outcome after total knee arthroplasty under general or spinal anesthesia, a randomized study
    Medical condition: Patients undego total knee arthroplasty operation in general or spinal anaesthesia because of osteoarthritis, rheumatoid arthritis or other degenerative condition of the knee
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004859 10031174 Osteoarthrosis LLT
    19.0 100000004859 10031158 Osteo arthritis knees LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-003016-60 Sponsor Protocol Number: CSMC021C-2302 Start Date*: 2007-10-12
    Sponsor Name:Nordic Bioscience A/S
    Full Title: A Randomized, Double-Blind, Multi-Center, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Oral Salmon Calcitonin in the Treatment of Subjects with Knee Osteoarthritis.
    Medical condition: Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031161 Osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) BE (Completed) PL (Completed) GB (Completed) CZ (Prematurely Ended) ES (Completed)
    Trial results: View results
    EudraCT Number: 2013-001689-41 Sponsor Protocol Number: RR11/9858 Start Date*: 2013-11-20
    Sponsor Name:University of Leeds
    Full Title: Pain Reduction with Oral Methotrexate in knee Osteoarthritis, a pragmatic phase III trial of Treatment Effectiveness
    Medical condition: Knee osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    18.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    18.0 10028395 - Musculoskeletal and connective tissue disorders 10023476 Knee osteoarthritis LLT
    18.0 10028395 - Musculoskeletal and connective tissue disorders 10031166 Osteoarthritis knees LLT
    18.0 10028395 - Musculoskeletal and connective tissue disorders 10031165 Osteoarthritis knee LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2017-004581-10 Sponsor Protocol Number: CL2-201086-002 Start Date*: 2018-09-04
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Efficacy and safety of 3 doses of S201086/GLPG1972 administered orally once daily in patients with knee osteoarthritis. A 52-week international, multi-regional, multi-center, randomized, double-bli...
    Medical condition: Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) HU (Completed) DK (Completed) PL (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2017-001185-20 Sponsor Protocol Number: 167700-005CL Start Date*: 2017-12-05
    Sponsor Name:Proximagen Limited
    Full Title: A Randomized, Double Dummy, Parallel Arm, Placebo and Active Controlled, Double Blind, Study of the Safety and Efficacy of PRX167700 as Monotherapy in Adults with Moderate to Severe Knee Pain Due ...
    Medical condition: Moderate to Severe Knee Pain Due to Osteoarthritis in subjects who are Inappropriate for Oral Non steroidal Anti inflammatory Therapy
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10023476 Knee osteoarthritis LLT
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031165 Osteoarthritis knee LLT
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10024776 Localised osteoarthritis LLT
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031166 Osteoarthritis knees LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-002963-92 Sponsor Protocol Number: CLRX712A12201 Start Date*: 2020-02-05
    Sponsor Name:Novartis Pharma AG
    Full Title: A randomized, placebo-controlled, subject and investigator blinded study investigating the safety, tolerability and preliminary efficacy of 8-week treatment with intra-articular LRX712 to regenerat...
    Medical condition: Cartilage injuries
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-004046-18 Sponsor Protocol Number: CL3-12911-040 Start Date*: 2012-02-23
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Knee joint replacement over 5 years in patients with knee osteoarthritis. A long term follow up study in patients of the CL3-12911-018 study.
    Medical condition: Osteoarthritis The medical condition investigated in the CL3-12911-018 study was osteoarthritis. The applied CL3-12911-040 trial, CL3-12911-018 follow-up study, is thus performed in osteoarthrit...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) DE (Prematurely Ended) AT (Completed) BE (Completed) PL (Prematurely Ended) ES (Prematurely Ended) IT (Prematurely Ended) DK (Prematurely Ended) LT (Prematurely Ended) PT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-008593-31 Sponsor Protocol Number: 2PX-OA-03 Start Date*: 2009-04-03
    Sponsor Name:SantoSolve A/S
    Full Title: A 26 week placebo-controlled, randomised, double-blind, parallel group study of the efficacy and safety of 2PX (topical strontium chloride hexahydrate) in patients with pain due to osteoarthritis o...
    Medical condition: pain associated with osteoarthritis of the knee
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031161 Osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005956-34 Sponsor Protocol Number: 0822-011 Start Date*: 2007-03-14
    Sponsor Name:Merck Sharp & Dohme Ltd
    Full Title: A Phase IIa Randomized, Placebo-Controlled Clinical Trial to Study the Safety and Efficacy of MK-0822 in Patients with Osteoarthritis
    Medical condition: Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10031161 Osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-004313-41 Sponsor Protocol Number: 47659 Start Date*: 2014-05-19
    Sponsor Name:UMCG
    Full Title: Effect of pre-operative pain treatment by means of duloxetine on postoperative outcome after total hip or knee arthroplasty
    Medical condition: Osteoarthritis (knee or hip)
    Disease: Version SOC Term Classification Code Term Level
    19.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    19.0 10028395 - Musculoskeletal and connective tissue disorders 10023476 Knee osteoarthritis LLT
    19.0 10028395 - Musculoskeletal and connective tissue disorders 10020108 Hips osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-003232-31 Sponsor Protocol Number: TDU11685-ACT12505 Start Date*: 2011-11-03
    Sponsor Name:sanofi-aventis recherche et développement
    Full Title: A two part protocol to assess, using double blind placebo control, the safety, tolerability, and pharmacokinetics of ascending single doses of a new intra-articular administration formulation of SA...
    Medical condition: KNEE OSTEOARTHRITIS
    Disease: Version SOC Term Classification Code Term Level
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-003154-80 Sponsor Protocol Number: 2020CLI Start Date*: 2020-12-08
    Sponsor Name:Mucos Pharma GmbH & Co. KG
    Full Title: A Randomized, Double-blind, Placebo-controlled, Crossover Study to Investigate the Mechanism of Action of an Oral Enzyme Treatment with Bromelain, Trypsin and Rutoside versus Placebo in Subjects wi...
    Medical condition: Subjects suffering from knee Osteoarthitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-004049-26 Sponsor Protocol Number: MTX-071-P02 Start Date*: 2017-11-23
    Sponsor Name:Mestex
    Full Title: Lopain (MTX-071 / resiniferatoxin) An open label, single dose phase Ib/IIa study to determine the safety and clinical effects of intra-articular injections of low doses of Lopain (MTX-071) in pa...
    Medical condition: chronic osteoarthritic knee-joint pain
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2005-004145-34 Sponsor Protocol Number: CSMC021C-2301 Start Date*: 2005-10-20
    Sponsor Name:Nordic Bioscience A/S
    Full Title: A Randomized, Double-Blind, Multi-Center, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Oral Salmon Calcitonin in the Treatment of Subjects with Knee Osteoarthritis.
    Medical condition: This is a phase III trial. The population will be ambulatory men and women with knee osteoarthritis between 51 and 80 years old, in general good health.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031161 Osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) CZ (Completed) EE (Completed)
    Trial results: View results
    EudraCT Number: 2004-001713-34 Sponsor Protocol Number: A3471119 Start Date*: 2005-01-11
    Sponsor Name:Pfizer Limited
    Full Title: RANDOMIZED, DOUBLE-BLIND, MULTICENTER STUDY OF THE EFFICACY, TOLERABILITY AND SAFETY OF VALDECOXIB (BEXTRA®)10 MG OD VS. DICLOFENAC SODIUM 50 MG TDS FOR 6 WEEKS IN SUBJECTS WITH OSTEOARTHRITIS OF T...
    Medical condition: Osteoarthritis of the knee
    Disease: Version SOC Term Classification Code Term Level
    10031161
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-004805-34 Sponsor Protocol Number: TDU13828-ACT13830 Start Date*: 2015-04-02
    Sponsor Name:Sanofi-aventis Research & Development
    Full Title: A Two Part Protocol Using Double Blind Placebo Control to Assess the Safety, Tolerability, and Pharmacokinetics of Single Escalating Intra-articular Doses Followed by Assessment of Efficacy, Safety...
    Medical condition: Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2017-000623-27 Sponsor Protocol Number: EC_01_2017 Start Date*: 2017-09-11
    Sponsor Name:Fundacion para la investigacion biomedica HUPA
    Full Title: Role of autologous biological therapy in knee osteoarthritis. Intraosseous application of plasma rich in growth factors , improve of functional capacity and pain, compared to intraarticular applic...
    Medical condition: Knee osteoarthritis.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-001457-26 Sponsor Protocol Number: A6171016 Start Date*: 2008-04-24
    Sponsor Name:Pfizer Inc, 235 East 42nd Street, New York, NY 10017
    Full Title: A LONG-TERM, RANDOMIZED, DOUBLE-BLIND, PARALLEL-GROUP, PLACEBO-CONTROLLED, RADIOGRAPHIC STUDY TO INVESTIGATE THE SAFETY AND EFFICACY OF ORALLY ADMINISTERED SD-6010 IN SUBJECTS WITH SYMPTOMATIC OSTE...
    Medical condition: Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: HU (Completed) BE (Completed) DE (Completed) ES (Completed) CZ (Completed) SK (Completed) IT (Completed)
    Trial results: View results
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