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Clinical trials for Liver failure

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44349   clinical trials with a EudraCT protocol, of which   7376   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    1,286 result(s) found for: Liver failure. Displaying page 1 of 65.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2013-003349-41 Sponsor Protocol Number: ERASMECMI Start Date*: 2013-10-03
    Sponsor Name:Erasme hospital
    Full Title: what are the optimal doses of cefuroxime for cirrhotic patients?
    Medical condition: Cirrhotic patients with infection requiring treatment with cefuroxime
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004871 10024678 Liver failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-001705-21 Sponsor Protocol Number: 030705 Start Date*: 2007-04-05
    Sponsor Name:AZIENDA SANITARIA OSPEDALIERA S. GIOVANNI BATTISTA DI TORINO
    Full Title: Phase II study to evaluate hepatic function and clinical aspects in patients with severe hepatic cirrhosis treated with multiple cycle of stem cells mobilisation by G-CSF administration.
    Medical condition: Hepatic cirrhosis with severe liver dysfunction
    Disease: Version SOC Term Classification Code Term Level
    6.1 10019663 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-005108-33 Sponsor Protocol Number: Short2-INF-RIBA Start Date*: 2005-02-10
    Sponsor Name:AZIENDA SANITARIA OSPEDALIERA S. GIOVANNI BATTISTA DI TORINO
    Full Title: RANDOMISED CONTROLLED STUDY ON EARLY RENSPONSE TO COMBINED ANTIVIRAL THERAPY IN CHRONIC H EPATITIS C PATIENTS GENOTIPE 2 AND 3 WITH HCV-RNA NEGATIVE WEEK 4
    Medical condition: SOSTAINED BIOCHEMICAL AND VIROLOGICAL RESPONSE TO COMBINADET THERAPY PEGILATED RIBAVIRIN IN CHRONIC HEPATITIES PATIENTS G 2 AND 3
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019663 Hepatic failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-005112-83 Sponsor Protocol Number: Short1/4-INF-RIBA Start Date*: 2005-02-10
    Sponsor Name:AZIENDA SANITARIA OSPEDALIERA S. GIOVANNI BATTISTA DI TORINO
    Full Title: RANDOMISED CONTROLLED STUDY ON EARLY RESPONSE TO COMBINED ANTIVIRAL THERAPY IN CHRONIC EPATITES C PATIENT GENOTIPE 1 AND 4 WITH HCV RNA NEGATIVE WEEK 6
    Medical condition: SOSTAINED BIOCHEMICAL AND VIROLOGICAL RESPONSE TO COMBINATED THERAPY PEGILATED RIBAVIRIN IN CHRONIC EPATITIES PATIENTS G 1 AND 4
    Disease: Version SOC Term Classification Code Term Level
    6.1 10019663 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-020657-14 Sponsor Protocol Number: ALF-5755_P2_ALF Start Date*: 2011-07-04
    Sponsor Name:Alfact Innovation
    Full Title: A multicentre, double-blind, randomized, placebo-controlled study to evaluate the efficacy and the safety of ALF-5755 in patients with nonacetaminophen severe acute hepatitis and early stage acute ...
    Medical condition: Acute liver failure
    Disease: Version SOC Term Classification Code Term Level
    14.1 10019805 - Hepatobiliary disorders 10049844 Acute liver failure LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-002079-16 Sponsor Protocol Number: E2013_PK_CASPO70_LIVERFAILURE Start Date*: 2013-09-05
    Sponsor Name:Hospital Erasme
    Full Title: Pharmacokinetics of Caspofungin after one dose in patients with liver failure.
    Medical condition: The pharmacokinetics parameters of caspofungin will be studied for the patient admitted for alcoholic hepatitis or decompensated cirrhosis (Child-Pugh score 7-15).
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004871 10024678 Liver failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-004031-23 Sponsor Protocol Number: E2012AILIVER Start Date*: 2014-08-26
    Sponsor Name:Hopital Erasme
    Full Title: Serum pharmacokinetics of Caspofungin in patients with liver failure.
    Medical condition: The patient admitted for alcoholic hepatitis or decompensated cirrhosis (Child-Pugh score of 10-15) presenting with invasive aspergillosis (proven or probable) and treated by caspofungin.
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004871 10024678 Liver failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-003023-20 Sponsor Protocol Number: UCL-PLTP-002 Start Date*: 2008-09-11
    Sponsor Name:Cliniques universitaires Saint-Luc
    Full Title: TACROLIMUS – DACLIZUMAB - MYCOPHENOLATE MOFETIL IMMUNE PROPHYLAXIS IN PEDIATRIC LIVER TRANSPLANTATION. An open, pilot, investigator-driven study in 20 recipients
    Medical condition: Liver transplantation
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024678 Liver failure LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2008-008754-23 Sponsor Protocol Number: CILT08 Start Date*: 2009-12-16
    Sponsor Name:University Medical Center Göttingen
    Full Title: A Therapeutic Exploratory Study to Determine the Efficacy and Safety of Calcineurin-Inhibitor-Free de-novo Immunosuppression after Liver Transplantation.
    Medical condition: Patients with renal dysfunction undergoing liver transplantation
    Disease: Version SOC Term Classification Code Term Level
    14.0 10019805 - Hepatobiliary disorders 10019846 Hepatorenal syndrome PT
    14.0 10038359 - Renal and urinary disorders 10038474 Renal insufficiency LLT
    14.0 10019805 - Hepatobiliary disorders 10024678 Liver failure LLT
    14.0 10019805 - Hepatobiliary disorders 10024667 Liver cirrhosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-000316-29 Sponsor Protocol Number: 3571 Start Date*: Information not available in EudraCT
    Sponsor Name:King's College Hospital NHS Foundation Trust
    Full Title: Hepatocytes co-encapsulated with mesenchymal stromal cells in alginate microbeads for the treatment of acute liver failure in paediatric patients: HELP study
    Medical condition: Acute liver failure in paediatric patients
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004871 10049844 Acute liver failure LLT
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2005-000837-39 Sponsor Protocol Number: CCD01 Start Date*: 2007-08-15
    Sponsor Name:Cytonet GmbH & Co. KG
    Full Title: Open, randomized, prospective, controlled, multicentre study to evaluate the efficacy and safety of multiple intraportal applications of liver cell suspension in patients with acute liver failure n...
    Medical condition: Acute Liver Failure Subgroups of patients with indications falling under ICD classification codes:K70.4, K71, K72, K75, K76, K77
    Disease: Version SOC Term Classification Code Term Level
    9.1 10049844 Acute liver failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) GB (Prematurely Ended) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016176-78 Sponsor Protocol Number: 2009-016176-78 Start Date*: 2010-02-08
    Sponsor Name:AZIENDA OSPEDALIERA DI PADOVA
    Full Title: Terapy with everolimus in liver transplant.
    Medical condition: liver transplant
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019805 SOC
    9.1 10016152 LLT
    9.1 10016152 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-020212-11 Sponsor Protocol Number: 2010-338 Start Date*: 2010-09-09
    Sponsor Name:Overlæge dr.med. Frederik Grønhøj
    Full Title: Enkelt dosis (single dosis) farmakokinetik af 9-cis-retinoic acid (Alitretinoin, Toctino®) hos patienter med moderat til svær lever insufficiens.
    Medical condition: At undersøge enkeltdosis-farmakokinetikken af 9-cis-RA (Alitretinoin, Toctino®) og dets metaboliter hos patienter med moderat til svær leverinsufficiens og frivillige raske forsøgspersoner.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10024678 Liver failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-002226-36 Sponsor Protocol Number: N-003-CRD002 Start Date*: 2016-11-04
    Sponsor Name:Noorik Biopharmaceuticals AG
    Full Title: A double-blind, placebo-controlled, escalating-dose study of the effect of N-003 on renal function, pharmacodynamics, pharmacokinetics, safety and tolerability in patients with advanced liver disease.
    Medical condition: Decompensated cirrhosis of the liver
    Disease: Version SOC Term Classification Code Term Level
    19.0 10019805 - Hepatobiliary disorders 10019641 Hepatic cirrhosis PT
    19.0 100000004857 10038448 Renal failure NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-001177-32 Sponsor Protocol Number: HEP101 Start Date*: 2016-08-09
    Sponsor Name:Promethera Biosciences
    Full Title: Multicenter Phase II Safety and Preliminary Efficacy Study of 2 dose regimens of HepaStem in Patients with Acute on Chronic Liver Failure
    Medical condition: The study will recruit cirrhotic patients who are hospitalized for Acute-on-chronic liver failure (ACLF) or Acute Decompensation at risk of developing ACLF. ACLF combines an acute deterioration of...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004871 10008954 Chronic liver disease and cirrhosis LLT
    20.1 100000004871 10049844 Acute liver failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) FR (Completed) ES (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2009-012763-34 Sponsor Protocol Number: V.1 Start Date*: 2009-12-28
    Sponsor Name:Medizinische Universität Wien, Univ. Klinik für Anästhesie, Allg. Intensivmedizin u Schmerztherapie
    Full Title: Reversal of neuromuscular blockage in Patients with End Stage Hepatic Failure (listed for Liver Transplantation)
    Medical condition: Patients with liver-failure undergoing surgery and receiving Rocuronium. Sugammadex is approved for recovery of Rocuronium. There are to date no clinical data to Sugammadex in patients with liver ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-002567-42 Sponsor Protocol Number: 5A Start Date*: 2015-07-15
    Sponsor Name:Stockholm County Council, Karolinska University Hospital Huddinge, Dept of Anesthesiology and Intensive Care
    Full Title: Predictors of albumin synthesis rate in severe liver failure. An open exploratory study in patients with chronic liver failure assessed for liver transplantation
    Medical condition: Severe chronic liver failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-005628-13 Sponsor Protocol Number: IRRB/34/12 Start Date*: 2012-12-19
    Sponsor Name:ISTITUTO MEDITERRANEO PER I TRAPIANTI E TERAPIE AD ALTA SPECIALIZZAZIONE
    Full Title: Transplantation of Human Fetal Liver Cells for the Treatment of Patients with Decompensated Liver Cirrhosis
    Medical condition: liver cirrhosis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10019805 - Hepatobiliary disorders 10019669 Hepatic fibrosis and cirrhosis HLT
    14.1 10019805 - Hepatobiliary disorders 10019641 Hepatic cirrhosis PT
    14.1 10019805 - Hepatobiliary disorders 10019664 Hepatic failure and associated disorders HLT
    14.1 10019805 - Hepatobiliary disorders 10019805 Hepatobiliary disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-006227-38 Sponsor Protocol Number: 11.017 Start Date*: 2012-05-01
    Sponsor Name:Ove B. Schaffalitzky de Muckadell
    Full Title: “Assessment of fibrotic liver disease in a medical admission ward and intervention with losartan as antifibrotic therapy in patients with alcoholic liverdisease”
    Medical condition: Fibrotic alcoholic liver disease is in early stages often completely asymptomatic. Fully developed cirrhosis affect a wide range of physiological conditions. Eksamples are portal hypertension and f...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10019805 - Hepatobiliary disorders 10001627 Alcoholic liver disease PT
    14.1 10019805 - Hepatobiliary disorders 10001626 Alcoholic liver damage, unspecified LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-003051-11 Sponsor Protocol Number: HEP102-DHELIVER Start Date*: 2019-12-04
    Sponsor Name:Promethera Therapeutics
    Full Title: Randomized, placebo-controlled, double blind, multi-centre Phase IIb study to evaluate the efficacy and safety of HepaStem in patients with Acute on Chronic Liver Failure (ACLF) - DHELIVER
    Medical condition: Cirrhotic patients who are hospitalized for Acute on chronic liver failure (ACLF), ACLF combines an acute deterioration of liver function in an individual with pre-existing chronic liver disease a...
    Disease: Version SOC Term Classification Code Term Level
    24.0 10019805 - Hepatobiliary disorders 10077305 Acute on chronic liver failure PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Trial now transitioned) BE (Trial now transitioned) DE (Trial now transitioned) LV (Trial now transitioned) LT (Trial now transitioned) SK (Trial now transitioned) GB (GB - no longer in EU/EEA) DK (Trial now transitioned) PL (Trial now transitioned) PT (Completed) EE (Trial now transitioned) AT (Trial now transitioned) ES (Ongoing) NL (Trial now transitioned) SI (Completed) FR (Trial now transitioned) IT (Trial now transitioned)
    Trial results: (No results available)
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