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Clinical trials for Matrix

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    154 result(s) found for: Matrix. Displaying page 1 of 8.
    1  2  3  4  5  6  7  8  Next»
    EudraCT Number: 2015-003674-32 Sponsor Protocol Number: 1.1:12-6-2015 Start Date*: 2016-02-23
    Sponsor Name:Leiden University Medical Center
    Full Title: The effect of Telmisartan on inflammatory processes in the vascular wall of abdominal aortic aneurysms.
    Medical condition: Abdominal aortic aneurysm with an indication for elective open surgical repair.
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-003584-11 Sponsor Protocol Number: MACT-IBK-2015 Start Date*: 2015-12-11
    Sponsor Name:Medical University Innsbruck
    Full Title: Matrix-associated autologous chrondrocyte transplantation for grade four cartilage lesions of the knee joint - clinical and radiological outcome in correlation to the initial cell count of the cho...
    Medical condition: Cartilage lesion
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004859 10072638 Articular cartilage defect LLT
    18.0 100000004865 10064113 Cartilage allograft LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2004-004876-36 Sponsor Protocol Number: 05/Q0108/5 Start Date*: 2005-04-15
    Sponsor Name:Addenbrookes Hospital NHS Trust
    Full Title: AN INVESTIGATION INTO THE ROLE OF MATRIX METALLOPROTEINASES (MMP’s) IN LOWER LIMB VASCULAR RESTENOSIS
    Medical condition: Post angioplasty and post vein graft stenosis.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-002365-34 Sponsor Protocol Number: PM1434 Start Date*: 2015-10-08
    Sponsor Name:Polichem S.A.
    Full Title: A RANDOMIZED, DOUBLE-BLIND, VEHICLE-CONTROLLED, PARALLEL-GROUP TRIAL TO ASSESS THE EFFICACY, SAFETY AND TOLERABILITY OF P-3073 FOR TOPICAL TREATMENT OF NAIL PSORIASIS
    Medical condition: Mild to moderate psoriatic fingernail/s
    Disease: Version SOC Term Classification Code Term Level
    18.0 10040785 - Skin and subcutaneous tissue disorders 10028703 Nail psoriasis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LV (Completed) DE (Completed) CZ (Completed) PL (Completed) BG (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2016-001265-92 Sponsor Protocol Number: VAC065 Start Date*: 2016-06-24
    Sponsor Name:University of Oxford, CTRG
    Full Title: A Phase I/IIa Sporozoite Challenge Study to Assess the Safety and Protective Efficacy of adjuvanted R21 at different doses and the Combination Malaria Vaccine Candidate Regimen of adjuvanted R21 + ...
    Medical condition: Plasmodium falciparum infection
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-019706-16 Sponsor Protocol Number: PM0812 Start Date*: 2010-07-27
    Sponsor Name:POLICHEM
    Full Title: A randomized, double blind, placebo controlled, parallel groups, pilot study to assess the effects of two new nail lacquers, cyclosporine 5% and calcipotriol 0.005%, in the treatment of nail psoriasis
    Medical condition: Nail psoriasis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028703 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) LV (Completed)
    Trial results: View results
    EudraCT Number: 2006-006727-39 Sponsor Protocol Number: AGO/2006/012 Start Date*: 2007-10-18
    Sponsor Name:University Hospital Ghent
    Full Title: A prospective randomised controlled trial on the use of BMP-7 (Bone Morphogenetic Protein-7) (OP-1®) and demineralised bone matrix (DBM) in tibial non-union.
    Medical condition: non-union of the diaphysis of the tibia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2009-011125-14 Sponsor Protocol Number: RV4104A-2008-548 Start Date*: 2009-07-06
    Sponsor Name:Pierre Fabre Dermatologie
    Full Title: A multicentre, randomized, controlled study of the efficacy, safety and cost-effectiveness of a sequential therapy with RV4104A ointment, ciclopiroxolamine cream and ciclopirox film-forming solutio...
    Medical condition: Patients suffering from distal-lateral or lateral subungual onychomycosis of one great toenail (the target nail) without matrix involvement
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030338 Onychomycosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2019-002872-14 Sponsor Protocol Number: VAC079 Start Date*: 2019-11-12
    Sponsor Name:University of Oxford / Clinical Trials and Research Governance
    Full Title: A Phase I/IIa clinical trial to assess the safety, immunogenicity and efficacy of the blood-stage Plasmodium vivax malaria vaccine candidate PvDBPII in Matrix M1 in healthy adults living in the UK
    Medical condition: Plasmodium vivax malaria
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10047665 Vivax malaria (benign tertian) LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2021-001341-12 Sponsor Protocol Number: UV/AP/21 Start Date*: 2023-04-14
    Sponsor Name:Red Andaluza de Diseño y Traslación en Terapias Avanzadas - Fundación Pública Andaluza Progreso y Salud M.P.
    Full Title: Phase I-II, Multicenter, Randomized, Controlled, Proof of Concept Clinical Trial to determine feasibility, safety and efficacy of the use of Allogenic adipose-derived adult mesenchymal stem cells e...
    Medical condition: Venous ulcer
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004858 10047259 Venous ulcer NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-001066-15 Sponsor Protocol Number: LR19912019 Start Date*: 2019-08-16
    Sponsor Name:Merete Hædersdal
    Full Title: Treatment of hypertrophic scars using needle-free jet-injection of triamcinolone and 5-Fluorouracile: a prospective, controlled, randomized, single-blinded split-lesion trial.
    Medical condition: Hypertrophic scars on 20 participants
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10070845 Skin scarring LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2019-004637-16 Sponsor Protocol Number: FJD-UHC-19-01 Start Date*: 2020-11-13
    Sponsor Name:FUNDACION JIMENEZ DIAZ HEALTH RESEARCH INSTITUTE
    Full Title: Pilot, single-center, non-comparative clinical trial to assess the safety and preliminary efficacy of the administration of adipose tissue-derived MSCs (MSCs-TA) injected at the edges of the ulcer ...
    Medical condition: Lower limbs Chronic Wounds
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-006611-68 Sponsor Protocol Number: shey01.2006 Start Date*: 2007-05-07
    Sponsor Name:academic hospital Maastricht
    Full Title: Valsartan on top of standard therapy as a novel therapeutic strategy to treat cardiac dysfunction in patients with infammatory cardiomyopathies
    Medical condition: patients suffering from heartfailure and inflammatory cardiomyopthies
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-000944-41 Sponsor Protocol Number: FenS-FenD Start Date*: 2015-04-20
    Sponsor Name:FONDAZIONE IRCCS "ISTITUTO NAZIONALE DEI TUMORI"
    Full Title: A PILOT STUDY TO TEST THE FEASIBILITY OF A TWO-ARM, DOUBLE BLIND, PARALLEL-GROUP, RANDOMIZED CONTROLLED TRIAL FOR THE COMPARISON OF THE DURATION OF THE ANALGESIC EFFICACY OF A SINGLE MATRIX TRANSDE...
    Medical condition: Patients with oncological pain
    Disease: Version SOC Term Classification Code Term Level
    20.0 10018065 - General disorders and administration site conditions 10033371 Pain PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-000413-48 Sponsor Protocol Number: 8.1(IRE),2017.03.24 Start Date*: 2015-07-01
    Sponsor Name:ACS Biomarker
    Full Title: Bioprofiling response to mineralocorticoid receptor antagonists for the prevention of heart failure. A proof of concept clinical trial within the EU FP 7 “HOMAGE” programme « Heart OMics in AGing
    Medical condition: Elderly patients with Clinical and Biological risk factors for developing heart failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Prematurely Ended) NL (Prematurely Ended) GB (Prematurely Ended) DE (Completed) IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2018-002115-96 Sponsor Protocol Number: SCC215/P002900 Start Date*: 2021-04-23
    Sponsor Name:Klinikum Stuttgart, Landeshauptstadt Stuttgart gKAöR
    Full Title: Optimizing MATRix as remission induction in PCNSL: De-escalated induction treatment in newly diagnosed primary CNS lymphoma – a randomized phase III trial
    Medical condition: Primary diffuse large B-cell lymphoma (DLBCL) of the central nervous system is a rare disorder confined to the cerebral parenchyma, leptomeninges, eyes or spinal cord. It accounts for 4 to 6% of al...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned) AT (Trial now transitioned) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-001411-71 Sponsor Protocol Number: R475-OA-1815 Start Date*: 2018-12-03
    Sponsor Name:Regeneron Pharmaceuticals, Inc.
    Full Title: Study to Evaluate Synovial Fluid in the Phase 3 Fasinumab Program for Osteoarthritis of the Knee and Hip
    Medical condition: Pain due to osteoarthritis of the knee
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) PL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-002625-35 Sponsor Protocol Number: PERIOC_CTP001 Start Date*: 2015-01-26
    Sponsor Name:PerioC Ltd
    Full Title: The effect of locally delivered ciclosporin as an adjunct to healing after treatment of periodontal pockets
    Medical condition: Moderate to severe chronic periodontitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-000291-25 Sponsor Protocol Number: 14I-BMT01 Start Date*: 2014-09-10
    Sponsor Name:IBSA Institut Biochimique S.A.
    Full Title: A single-center, prospective, randomized, double-blind, intra-patient (left-to-right) placebo-controlled, pilot study to assess the efficacy and safety of a betamethasone valerate 0.1% medicated pl...
    Medical condition: Nail Psoriasis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-000327-40 Sponsor Protocol Number: 20110151 Start Date*: 2013-05-27
    Sponsor Name:Amgen Inc.
    Full Title: A Double-blind, Randomized, Placebo-controlled, Multicenter, Dose Escalation Study to Select and Evaluate an Oral Modified Release Formulation of Omecamtiv Mecarbil in Subjects with Heart Failure ...
    Medical condition: Chronic Heart Failure and Left Ventricular Systolic Dysfunction
    Disease: Version SOC Term Classification Code Term Level
    16.1 10007541 - Cardiac disorders 10063083 Chronic left ventricular failure PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) GB (Completed) LT (Completed) CZ (Completed) HU (Completed) IT (Completed) BG (Completed) DE (Completed) BE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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