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Clinical trials for Microdialysis

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    54 result(s) found for: Microdialysis. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2006-001784-35 Sponsor Protocol Number: DicloMD Start Date*: 2006-05-12
    Sponsor Name:Nuvo research Inc
    Full Title: Validation of the microdialysis technique as a tool to assess local delivery of topical drugs used in the treatment of osteoarthritis of superficial joints
    Medical condition: Healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-002758-29 Sponsor Protocol Number: mdb/001 Start Date*: 2012-05-04
    Sponsor Name:Med. Univ. Wien, Uk für Innere Medizin I
    Full Title: Cerebral microdialysis in neurointensive care patients to determine brain penetration of antibiotics. An open label explorative study.
    Medical condition: Cerebral microdialysis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2014-000826-39 Sponsor Protocol Number: S-20130165 Start Date*: 2014-06-17
    Sponsor Name:Ortopædkirurgisk afdeling Odense Universitetshospital
    Full Title: Determining the tissue concentration of dicloxacillin using Microdialysis (on healthy male subjects)
    Medical condition: The trial is conducted on healthy male volunteers. An intravenous dose of 2 grams of dicloxacillin is administered intravenously and the muscle- and subcutaneous tissue concentrations are measured ...
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004862 10059428 Postoperative infection LLT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: Removed from public view
    EudraCT Number: 2019-000955-16 Sponsor Protocol Number: PIPLEVOLUNG Start Date*: 2020-01-28
    Sponsor Name:Medical University of Vienna
    Full Title: Pulmonary pharmacokinetics of piperacillin/tazobactam and levofloxacin in patients with chronic obstructive pulmonary disease or cystic fibrosis: Comparison of epithelial lining fluid, in-vivo micr...
    Medical condition: Pneumonia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-000010-38 Sponsor Protocol Number: PAEDMED_v1.0 Start Date*: 2018-03-20
    Sponsor Name:Department of Clinical Pharmacology/Medical University of Vienna
    Full Title: Development of intravascular microdialysis as a tool for therapeutic drug monitoring in children.
    Medical condition: cohort A: We will administer a single dose of vancomycin, cefuroxime or gentamicin to healthy volunteers. The administration of the antibiotics in cohort A is for study purposes only. cohort B: We...
    Disease:
    Population Age: Infants and toddlers, Children, Under 18, Adults Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-005486-34 Sponsor Protocol Number: A2500522 Start Date*: 2008-05-06
    Sponsor Name:GlaxoSmithKline Consumer Healthcare
    Full Title: A Pilot Study to Evaluate the Relative Bioavailability of Diclofenac as Measured by Microdialysis After Repeated Doses of Two Topical Diclofenac Formulations
    Medical condition: Not applicable as this study is to compare the extent of absorption of two topical gels.
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2013-001138-17 Sponsor Protocol Number: 240583 Start Date*: 2013-07-11
    Sponsor Name:Orthopedic Research in Aarhus
    Full Title: In vivo measurement of cefuroxime in subcutaneous and bone tissue using microdialysis
    Medical condition: Orthopedic infections
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004865 10050155 Knee prosthesis insertion LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2014-000258-12 Sponsor Protocol Number: 230189 Start Date*: 2014-10-15
    Sponsor Name:Orthopedic Research in Aarhus
    Full Title: Pharmacokinetics of vancomycin in cancellous and cortical bone obtained by microdialysis
    Medical condition: Orthopedic infections
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004865 10050155 Knee prosthesis insertion LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2012-004398-22 Sponsor Protocol Number: 1 Start Date*: 2013-07-01
    Sponsor Name:Afd. A, OUH
    Full Title: intraperitoneal microdialysis after server peritonitis
    Medical condition: server peritonitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2012-000379-18 Sponsor Protocol Number: 1.0 Start Date*: 2012-05-04
    Sponsor Name:Medizinische Universität Wien, Universitätsklinik für Klinische Pharmakologie
    Full Title: Plasma and synovial fluid pharmacokinetics of cefuroxime and linezolid in patients undergoing elective knee arthroscopy after a single intravenous dose of cefuroxime and linezolid: an exploratory m...
    Medical condition: Subjects under general anaesthesia after a knee surgery get a microdialysis probe insertio into the operated knee and a probe insertion into the thigh on the contralateral side. After the operation...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2016-001863-35 Sponsor Protocol Number: THAM Start Date*: 2016-06-21
    Sponsor Name:Universitätsklinik für Klinische Pharmakologie, Medizinische Universität Wien
    Full Title: Effects of Tromethamine on Cerebral Oxygenation and Metabolism in Patients Suffering Intractable Intracranial Hypertension – an exploratory study.
    Medical condition: Critically ill patients (SAH, ICB, AVM bleedings, malignant MCA infarcts) under sedation and mechanical ventilation in need of multimodality monitoring, including brain tissue oxygen monitoring and...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-000391-42 Sponsor Protocol Number: MD-01 Start Date*: 2013-01-22
    Sponsor Name:Martin-Luther-Universität Halle-Wittenberg
    Full Title: Investigation on the peritoneal tissue concentrations of antibiotics in surgical patients with peritonitis using microdialysis. Example: linezolide, tigecycline
    Medical condition: Peritonitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-003107-36 Sponsor Protocol Number: AmoClav-Protokoll2.0 Start Date*: 2005-10-21
    Sponsor Name:Department of Thoracic and Hyperbaric Surgery, University Medical School Graz
    Full Title: Pharmacokinetic of Amoxicillin and Clavulanacid in pneumonic, interstitial lung tissue measured by in vivo microdialysis, in patients with pleural empyema treated by decortication.
    Medical condition: To measure the time versus concentration profile of Amoxicillin and Clavulanacid in the interstitial space of infected lung tissue as the target site of infection following intravenous administrati...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2007-001701-19 Sponsor Protocol Number: ERTADIAB Start Date*: 2007-12-11
    Sponsor Name:CHU DE POITIERS
    Full Title: pharmacokinetic study by microdialysis of the distribution of ertapeneme and levofloxacine in infected foot ulcers of diabetics patients.
    Medical condition: infected foot ulcers in diabetic patient
    Disease: Version SOC Term Classification Code Term Level
    9.1 10060803 Diabetic foot infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-003858-31 Sponsor Protocol Number: 300319 Start Date*: 2023-02-16
    Sponsor Name:Aarhus University Hospital
    Full Title: Evaluating the vulnerability of traditional and transposition FAMM flaps using microdialysis
    Medical condition: Oral cavity cancer and infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-004189-33 Sponsor Protocol Number: REK322442 Start Date*: 2013-11-28
    Sponsor Name:Haukeland University Hospital
    Full Title: ULTRADIAN SUBCUTANEOUS HYDROCORTISONE (USHI) INFUSION IN ADDISON’S DISEASE
    Medical condition: Addison`s disease
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-004974-16 Sponsor Protocol Number: IL1ra03 Start Date*: 2018-11-08
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge
    Full Title: DOUBLE-BLIND PLACEBO-CONTROLLED RANDOMISED CLINICAL DOSE-RANGING STUDY TREATING MODERATE-SEVERE TRAUMATIC BRAIN INJURY PATIENTS WITH RECOMBINANT HUMAN INTERLEUKIN 1 RECEPTOR ANTAGONIST.
    Medical condition: We wish to study the drug Kineret in patients suffering from moderate-to-severe traumatic brain injury
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10060690 Traumatic brain injury LLT
    20.1 10029205 - Nervous system disorders 10051288 Central nervous system inflammation PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-001409-40 Sponsor Protocol Number: S334.2.002 Start Date*: 2009-03-04
    Sponsor Name:Solvay Pharmaceuticals B.V.
    Full Title: A Randomized, Double blind, Placebo-Controlled Dose Escalation Study to Investigate the Safety and Pharmacokinetics after Single and Multiple Doses of SLV334 in Sequential Cohorts of Patients with ...
    Medical condition: Moderate and severe Traumatic Brain Injury (TBI)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10060690 Traumatic brain injury PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) ES (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-002798-50 Sponsor Protocol Number: prostacyclin Start Date*: 2011-09-27
    Sponsor Name:Rune Rasmussen
    Full Title: Effect of prostacyclin infusion on cerebral vessels and metabolism in patients with subarachnoid haemorrhage
    Medical condition: Vasospasm following subarachnoid hemorrhage
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029205 - Nervous system disorders 10042320 Subarachnoid hemorrhage LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-003078-36 Sponsor Protocol Number: 727258 Start Date*: 2020-09-14
    Sponsor Name:Aarhus University Hospital
    Full Title: The RAS-study A reverse and anatomical prosthesis shoulder study Can we improve the prophylactic profile of antibiotic treatment in shoulder prosthesis surgery? - A clinical microdialysis study as...
    Medical condition: Orthopedic infections
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004862 10021799 Infection and inflammatory reaction due to other internal orthopedic device, implant, and graft LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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