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Clinical trials for Midazolam Hydrochloride

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    39 result(s) found for: Midazolam Hydrochloride. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2021-004789-36 Sponsor Protocol Number: 173-01 Start Date*: 2022-06-29
    Sponsor Name:Universität Heidelberg
    Full Title: Randomized, controlled trial of the use of intranasal midazolam for the treatment of terminal agitation in palliative care patients
    Medical condition: Terminal agitation in the final phase
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-003582-24 Sponsor Protocol Number: CLON01 Start Date*: 2015-06-15
    Sponsor Name:Universitätsklinikum Erlangen
    Full Title: A double blind, randomised, multicentre, active controlled, parallel-group, phase III trial to evaluate the efficacy, safety and pharmacokinetics of intravenous clonidine (hydrochloride) compared t...
    Medical condition: sedation in intensive care
    Disease: Version SOC Term Classification Code Term Level
    18.1 10029205 - Nervous system disorders 10039897 Sedation PT
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Completed) DE (Prematurely Ended) SE (Completed) IT (Prematurely Ended) CZ (Completed) EE (Prematurely Ended) ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-005215-42 Sponsor Protocol Number: KloMid02 Start Date*: 2013-04-12
    Sponsor Name:Department of Anesthesiology and Intensive Care Medicine
    Full Title: Children's mood/anxiety, pain, nausea and behavioral changes after premedication with Clonidine versus Midazolam in ENT day surgery.
    Medical condition: Preanesthetic Medication at ear-nose-throat surgery
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-012808-11 Sponsor Protocol Number: MID001 Start Date*: Information not available in EudraCT
    Sponsor Name:Therakind Limited
    Full Title: An open label, single dose, pharmacokinetic study of oromucosal midazolam administered to children from 3 months to less than 18 years undergoing routine elective surgery
    Medical condition: In the context of the trial, the IMP is to be used as anaesthetic premedication in children undergoing elective routine surgery. (The medical condition for marketing is acute seizures in children ...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10058073 Anaesthetic premedication LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006031-50 Sponsor Protocol Number: 3005013 Start Date*: 2007-04-24
    Sponsor Name:Orion Corporation Orion Pharma
    Full Title: A PROSPECTIVE, MULTI-CENTRE, RANDOMISED, DOUBLE-BLIND COMPARISON OF INTRAVENOUS DEXMEDETOMIDINE WITH MIDAZOLAM FOR CONTINUOUS SEDATION OF VENTILATED PATIENTS IN INTENSIVE CARE UNIT
    Medical condition: Patients requiring mechanical ventilation and sedation in ICU.
    Disease: Version SOC Term Classification Code Term Level
    8.0 10039897 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) GB (Completed) BE (Completed) NL (Completed) DE (Completed) FR (Completed) EE (Completed)
    Trial results: View results
    EudraCT Number: 2018-004480-31 Sponsor Protocol Number: PSIKET_001CZE Start Date*: 2020-07-14
    Sponsor Name:Národní ústav duševního zdraví
    Full Title: Psilocybin versus ketamine – fast acting antidepressant strategies in treatment-resistant depression
    Medical condition: The study will include 60 patients with pharmaco-resistant depression (30 male, 30 female, aged 18–65). The basic inclusion criterion is the diagnosis of pharmaco-resistant moderate to severe depre...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-005457-31 Sponsor Protocol Number: ANES003 Start Date*: 2012-04-16
    Sponsor Name:UZBrussel Department of Anesthesiology and Perioperative Medicine; Acute and Chronic Pain Therapy
    Full Title: The effect of the combination of midazolam with Ropivacaine in loco-regional anesthesia.
    Medical condition: All patients scheduled for limb surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-001814-34 Sponsor Protocol Number: OPI 04/006 Start Date*: 2006-09-12
    Sponsor Name:The Norwegian University of Science and Technology
    Full Title: Effects of hypothermia on the disposition of morphine, fentanyl, midazolam and propofol in intensive care unit patients
    Medical condition: Patients treated with therapeutic hypothermia (33-34 °C) and a control group of normothermic patients matched on sex, age and duration of morphine infusion.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: View results
    EudraCT Number: 2018-003421-28 Sponsor Protocol Number: 11-18 Start Date*: 2019-01-16
    Sponsor Name:St Patrick's Mental Health Services
    Full Title: Ketamine interleaved with electroconvulsive therapy for depression, a pragmatic randomised controlled pilot trial (KITE-Dep)
    Medical condition: Depression
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-000226-26 Sponsor Protocol Number: SHP615-301 Start Date*: 2020-02-13
    Sponsor Name:Shire
    Full Title: A Phase 3, Multicenter, Open-label Study to Determine the Efficacy, Safety, and Pharmacokinetics of Buccally Administered MHOS/SHP615 in Pediatric Patients with Status Epilepticus (Convulsive) in t...
    Medical condition: Acute Convulsive Seizures
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2005-003516-29 Sponsor Protocol Number: KKSK-251 Start Date*: 2006-08-18
    Sponsor Name:Universität zu Köln
    Full Title: Prospective, randomized, double-blinded clinical trial on remifentanil for analgesia and sedation of ventilated neonates and infants
    Medical condition: Meanwhile it is widely accepted, that ventilated newborns and infants should receive analgesia and sedation for ethical and medical reasons. In this context fentanyl belongs to the mosten often use...
    Disease:
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-014256-30 Sponsor Protocol Number: HU08/NEONAT/REMIFENTANIL Start Date*: 2009-09-11
    Sponsor Name:Hôpital Universitaire Des Enfants Reine Fabiola
    Full Title: Une analgésie de choix pour l'intubation des nouveau-nés : Etude multicentrique randomisée comparant le rémifentanil à l'association morphine-midazolam
    Medical condition: Preterm newborn & newborm requiring an elective endotacheal intubation
    Disease: Version SOC Term Classification Code Term Level
    12.0 10067450 Endotracheal intubation LLT
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-004097-15 Sponsor Protocol Number: GabA-01 Start Date*: 2015-10-23
    Sponsor Name:Wilhelminenspital
    Full Title: A single center, prospective, randomized, double blind, placebo-controlled, three-way cross-over study of the analgesic effects of Midazolam versus Placebo with Fentanyl as an active control in hum...
    Medical condition: nociceptive pain
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-004764-18 Sponsor Protocol Number: 01-17 Start Date*: 2017-07-24
    Sponsor Name:St Patrick’s Mental Health Services
    Full Title: Ketamine as an adjunctive therapy for Major Depression - a randomised controlled pilot trial: The KARMA-Dep Trial
    Medical condition: Depression
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: View results
    EudraCT Number: 2006-003285-34 Sponsor Protocol Number: Start Date*: 2006-08-30
    Sponsor Name:
    Full Title: Vergleich unterschiedlicher Strategien zur Analgosedierung in der interventionellen Radiologie bei der PTCD (perkutane transhepatische Cholangiodrainage): Eine kontrollierte, prospektive, randomisi...
    Medical condition: Anlage einer perkutanen transhepatischen Cholangiodrainage und Gallengangsstent bei Patienten mit mechanischer Cholestaste aufgrund von Tumoren, Entzündungen, Konkrementen in den Gallenwegen.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10002183 Analgesia intra/post op LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-004671-39 Sponsor Protocol Number: 2019/318 Start Date*: 2020-01-28
    Sponsor Name:Universitair Ziekenhuis Brussel (UZ Brussel)
    Full Title: The effect of handheld-multimedia versus midazolam premedication on the level of perioperative anxiety in pediatric day-care. A randomized controlled trial.
    Medical condition: Perioperative anxiety in children scheduled for an elective circumcision, dental care or tonsillectomy/adenoidectomy in day-care
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-005037-32 Sponsor Protocol Number: PSIKET_002CZE Start Date*: 2021-09-22
    Sponsor Name:Národní ústav duševního zdraví
    Full Title: Psilocybin - a strategy of rapid antidepressant response in depression comorbid with cancer, a randomized double-blind study with the possibility of entering open extension.
    Medical condition: Depressive disorder comorbid with cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 10037175 - Psychiatric disorders 10012378 Depression PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2021-004456-42 Sponsor Protocol Number: P2021/Anesth/MIDEXMRI Start Date*: 2022-06-21
    Sponsor Name:Hôpital Universitaire Des Enfants Reine Fabiola
    Full Title: Prospective, randomized, double-blind, double-dummy, active-controlled, phase 3 clinical trial comparing the safety and efficacy of intranasal dexmedetomidine to oral midazolam as premedication for...
    Medical condition: pre-school pediatric population undergoing magnetic resonance imaging
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-003109-92 Sponsor Protocol Number: CRFSPN004 Start Date*: 2020-03-20
    Sponsor Name:Trinity College Dublin
    Full Title: Ketamine as an adjunctive therapy for Major Depression (2) - a randomised controlled trial
    Medical condition: Major Depression
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-002495-18 Sponsor Protocol Number: SG2006/1 Start Date*: 2007-04-08
    Sponsor Name:Wrightington, Wigan and Leigh NHS Trust
    Full Title: The use of ketamine in combination with midazolam for the induction of conscious sedation during endoscopic retrograde cholangiopancreatography (ERCP).
    Medical condition: The study will not investigate any specific disease, but rather the sedation techniques used for endoscopic retrograde cholangiopancreatography, a form of endoscopy which can be used to diagnose an...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10014802 Endoscopic retrograde cholangiopancreatography LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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