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Clinical trials for Mortality

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    2,286 result(s) found for: Mortality. Displaying page 1 of 115.
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    EudraCT Number: 2012-002235-29 Sponsor Protocol Number: 1.0 Start Date*: 2012-10-23
    Sponsor Name:Medizinische Universität Wien - Universitätsklinik für klinische Pharmakologie
    Full Title: Does acetylsalicylic acid reduce the mortality of patients admitted to an Intensive Care Unit
    Medical condition: medical patients admitted to an intensive care unit
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-000497-38 Sponsor Protocol Number: DEX-PCH-VMNI Start Date*: 2016-08-23
    Sponsor Name:Ana Vallejo De la Cueva
    Full Title: Dexmedetomidine versus current clinical practice for non-invasive mechanical ventilation: a randomized clinical trial
    Medical condition: Accute respiratory insuffienciency
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-001582-16 Sponsor Protocol Number: RF-2016-02361583 Start Date*: 2018-08-09
    Sponsor Name:FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO
    Full Title: Efficacy of Albumin Replacement and Balanced Crystalloid Solutions in Septic Shock (the ALBIOSS-BALANCED trial): a 2-by-2 factorial, investigator-initiated, open-label, multicenter, randomized, con...
    Medical condition: Septic shock
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10040070 Septic shock PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-024263-40 Sponsor Protocol Number: PEx in DIC Version 1 Start Date*: 2011-09-08
    Sponsor Name:Medizinische Universität Wien, Univ. Klinik f. Klinische Pharmakologie
    Full Title: Plasma exchange as therapy for disseminated intrevascular coagulation (DIC)- a randomized-controlled trial
    Medical condition: Disseminated intravascular coagulation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-001333-13 Sponsor Protocol Number: 20-37815010 Start Date*: 2020-04-09
    Sponsor Name:Groupe Hospitalier Paris Saint-Joseph
    Full Title: Dexamethasone associated with hydroxychloroquine vs. hydroxychloroquine alone for the early treatment of severe ARDS caused by COVID-19 : a randomized controlled trial
    Medical condition: Acute Respiratory Distress Syndrome (ARDS) caused by SARS-Cov-2 infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-004886-33 Sponsor Protocol Number: A06-269 Start Date*: 2007-06-05
    Sponsor Name:University of Athens, Medical school
    Full Title: A DOUBLE-BLIND RANDOMIZED PLACEBO-CONTROLLED CLINICAL TRIAL OF THE SAFETY AND IMMUNOMODULATORY THERAPY FOR THE MANAGEMENT OF SEPSIS
    Medical condition: septic syndrome
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-003218-36 Sponsor Protocol Number: 82646 Start Date*: 2023-06-05
    Sponsor Name:Radboudumc
    Full Title: The safety of ticagrelor monotherapy after primary percutaneous coronary intervention for ST-elevation myocardial infarction and the effect on intramyocardial haemorrhage
    Medical condition: Acute myocardial infarction
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-005533-20 Sponsor Protocol Number: VOLATILE10600 Start Date*: 2014-12-11
    Sponsor Name:OSPEDALE SAN RAFFAELE IRCCS
    Full Title: VOLATILE ANESTHETICS TO REDUCE MORTALITY IN CARDIAC SURGERY. A MULTICENTRE RANDOMIZED CONTROLLER STUDY
    Medical condition: PATIENTS UNDERGOING CORONARY ARTERY BYOASS GRAFT SURGERY
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended) BE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001479-22 Sponsor Protocol Number: NCT03021525 Start Date*: 2017-08-04
    Sponsor Name:University Medical Center Hamburg-Eppendorf, Germany
    Full Title: Individualized perioperative hemodynamic goal-directed therapy in major abdominal surgery (iPEGASUS-trial)
    Medical condition: - Hemodynamic Instability - Cardiac Output - High Peroperative Complication
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001250-21 Sponsor Protocol Number: 2020/3078 Start Date*: 2020-04-03
    Sponsor Name:GUSTAVE ROUSSY
    Full Title: COVID-19 - Epidemiology of SARS-CoV-2 and Mortality to Covid19 Disease upon Hydroxychloroquine and Azithromycin Therapy in French Cancer patients
    Medical condition: Patients eligible for, or under, or recently treated by chemotherapy (CT) and/or immune-checkpoint blockade (ICB) for the treatment of solid tumors or hematological malignancies.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-003388-24 Sponsor Protocol Number: UCD/CRC/20/04 Start Date*: 2021-02-10
    Sponsor Name:University College Dublin [...]
    1. University College Dublin
    2. Monash University
    Full Title: A randomised, double-blind, placebo-controlled trial of erythropoietin alfa versus placebo in mechanically ventilated critically ill patients following traumatic injury
    Medical condition: Traumatic injury
    Disease: Version SOC Term Classification Code Term Level
    23.1 10022117 - Injury, poisoning and procedural complications 10022117 Injury, poisoning and procedural complications SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Ongoing) FI (Ongoing) SI (Ongoing) DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-000436-74 Sponsor Protocol Number: 432 Start Date*: 2007-11-27
    Sponsor Name:Poissy Hospital
    Full Title: Impact of two glucose control regimens by insulin on hospital mortality in intensive care unit patients (INSUREA Study)
    Medical condition: hyperglycemia in critical care unit patients
    Disease: Version SOC Term Classification Code Term Level
    9.1 10018424 Glucose metabolism disorders (incl diabetes mellitus) HLGT
    Population Age: Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-003539-56 Sponsor Protocol Number: 1.01 Start Date*: 2006-11-10
    Sponsor Name:Medical University of Vienna, Department of Internal Medicine IV
    Full Title: Simvastatin in patients with septic shock
    Medical condition: Septic shock
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2011-001099-21 Sponsor Protocol Number: 2010-04-23 Start Date*: 2011-05-19
    Sponsor Name:Population Health Research Institute
    Full Title: SIRS Steroids In caRdiac Surgery Trial
    Medical condition: From available evidence, corticosteroids attenuate the inflammatory response to CPB which is felt to contribute to morbidity and mortality in cardiac surgery patients. The meta-analysis of the lite...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2017-003510-16 Sponsor Protocol Number: EFC15156 Start Date*: 2018-05-07
    Sponsor Name:Lexicon Pharmaceuticals, Inc.
    Full Title: A Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Study to Evaluate the Effects of Sotagliflozin on Clinical Outcomes in Hemodynamically Stable Patients with Type 2 Diabet...
    Medical condition: Cardiovascular diseases
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10019279 Heart failure LLT
    21.1 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) NL (Completed) ES (Prematurely Ended) LV (Completed) LT (Completed) GB (Completed) BE (Completed) DK (Prematurely Ended) FR (Completed) AT (Completed) CZ (Prematurely Ended) DE (Completed) SK (Completed) HU (Completed) FI (Completed) PT (Completed) GR (Completed) PL (Completed) IE (Completed) IT (Completed) RO (Completed)
    Trial results: View results
    EudraCT Number: 2009-011817-26 Sponsor Protocol Number: BHS-UCB2009 Start Date*: 2010-10-21
    Sponsor Name:UZ Brussel VUB
    Full Title: A pilot study to assess the feasibility of unrelated umbilical cord blood transplantation with coinfusion of third-party mesenchymal stem cells after myeloablative or nonmyeloablative conditioning ...
    Medical condition: Adult patients with hematological malignancies
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-004896-60 Sponsor Protocol Number: LUMC2015-02 Start Date*: 2015-11-26
    Sponsor Name:Leiden University Medical Center
    Full Title: Decitabine-cytarabine chemotherapy in elderly AML and high risk MDS patients (> 65 years) with high early mortality risk
    Medical condition: Acute myeloid leukemia and high risk myelodysplasia
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001766-11 Sponsor Protocol Number: 2020-24 Start Date*: 2020-04-29
    Sponsor Name:ASSISTANCE PUBLIQUE HÔPITAUX DE MARSEILLE
    Full Title: Losartan and spironolactone treatment for COVID-19 patients with acute respiratory failure in intensive care unit
    Medical condition: Patients with Covid-19
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-002460-13 Sponsor Protocol Number: VITDALIZE Start Date*: 2017-01-03
    Sponsor Name:Medical University of Graz
    Full Title: Effect of high-dose vitamin D3 on 28-day mortality in adult critically ill patients with severe vitamin D deficiency: a multicenter, placebo-controlled double-blind phase III RCT
    Medical condition: Adult critically ill patients with severe vitamin D deficiency
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing) GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2020-002504-39 Sponsor Protocol Number: HERO-19 Start Date*: 2020-11-10
    Sponsor Name:University Medical Center Hamburg-Eppendorf
    Full Title: Hamburg Edoxaban foR anticoagulation in COvid-19 study
    Medical condition: COVID-19 [Coronavirus disease 2019]
    Disease: Version SOC Term Classification Code Term Level
    23.1 10042613 - Surgical and medical procedures 10084460 COVID-19 treatment PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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