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Clinical trials for Nose

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44349   clinical trials with a EudraCT protocol, of which   7376   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    425 result(s) found for: Nose. Displaying page 1 of 22.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2016-001530-10 Sponsor Protocol Number: NoPac01 Start Date*: 2017-02-20
    Sponsor Name:Royal Devon & Exeter NHS Foundation Trust
    Full Title: A randomised controlled trial of topical intranasal tranexamic acid versus placebo to reduce the need for nasal packing in patients presenting to the Emergency Department with spontaneous epistaxis.
    Medical condition: Atraumatic epistaxis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10015090 Epistaxis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-002385-23 Sponsor Protocol Number: AFT-MXCF-03 Start Date*: 2015-11-10
    Sponsor Name:AFT Pharmaceuticals Ltd
    Full Title: A phase 3 randomised, double blind, multiple dose, parallel group efficacy study of different doses of phenylephrine hydrochloride combined with paracetamol and/or ibuprofen in participants with na...
    Medical condition: nasal congestion
    Disease: Version SOC Term Classification Code Term Level
    18.0 10038738 - Respiratory, thoracic and mediastinal disorders 10028735 Nasal congestion PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-002443-10 Sponsor Protocol Number: 2011035 Start Date*: 2011-06-23
    Sponsor Name:Procter & Gamble Technical Centres Ltd., UK
    Full Title: A Randomized, Open-Label, Single-Dose, Parallel Group Study to Evaluate the Utility of Magnetic Resonance Imaging (MRI) in Demonstrating the Nasal Decongestant Efficacy of an Active Control (Vicks®...
    Medical condition: Nasal Congestion due to the common cold or hay fever
    Disease: Version SOC Term Classification Code Term Level
    13.1 10038738 - Respiratory, thoracic and mediastinal disorders 10028735 Nasal congestion PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-004959-35 Sponsor Protocol Number: GrassMATAMPL301 Start Date*: 2006-09-11
    Sponsor Name:Allergy Therapeutics (UK) Ltd
    Full Title: Efficacy and Safety/Tolerability of GrassMATAMPL, a Randomized, Placebo-Controlled, Double-Blind Study
    Medical condition: Type I respiratory hypersensitivity to cross-reacting grass pollens
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed) AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-005215-42 Sponsor Protocol Number: KloMid02 Start Date*: 2013-04-12
    Sponsor Name:Department of Anesthesiology and Intensive Care Medicine
    Full Title: Children's mood/anxiety, pain, nausea and behavioral changes after premedication with Clonidine versus Midazolam in ENT day surgery.
    Medical condition: Preanesthetic Medication at ear-nose-throat surgery
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-000580-93 Sponsor Protocol Number: SINTART2 Start Date*: 2013-05-04
    Sponsor Name:Fondazione IRCCS Istituto Nazionale Tumori
    Full Title: Multidisciplinary approach for poor prognosis sinonasal tumors: Phase II study of chemotherapy, photon and heavy ion radiotherapy integration for more effective and less toxic treatment in inoperab...
    Medical condition: Poor prognosis inoperable sinonasal tumors.
    Disease: Version SOC Term Classification Code Term Level
    15.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10060768 Nasal neoplasm PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-000075-33 Sponsor Protocol Number: SINTART1 Start Date*: 2013-05-04
    Sponsor Name:Fondazione IRCCS Istituto Nazionale Tumori
    Full Title: Multidisciplinary approach for poor prognosis sinonasal tumors: Phase II study of chemotherapy, surgery, photon and heavy ion radiotherapy integration for more effective and less toxic treatment in...
    Medical condition: Poor prognosis sinonasal tumors in operable patients.
    Disease: Version SOC Term Classification Code Term Level
    15.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10060768 Nasal neoplasm PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-001720-36 Sponsor Protocol Number: BAY E 4465/11764 Start Date*: 2005-10-24
    Sponsor Name:BAYER
    Full Title: A pivotal, placebo controlled, phaseIII study to compare efficacy and tollerability of a fixed combination, containing 500 mg ASA and 30 mg Pseudoephedrine, in comparison to its single components i...
    Medical condition: Cold related pain/fever e.g. sore throat, headache, ear eache, sinus pressure and nasal congestion.
    Disease: Version SOC Term Classification Code Term Level
    6.1 10028735 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-001591-11 Sponsor Protocol Number: 3.4.11.049 Start Date*: 2012-12-21
    Sponsor Name:Erasmus MC
    Full Title: Symptomatic treatment of pollen related allergic rhinoconjunctivitis and the relation with asthma with children in the General practice
    Medical condition: Allergic Rhinitis Asthma
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-005155-27 Sponsor Protocol Number: KCT09/2015-SeptaNazal-Double Start Date*: 2017-02-22
    Sponsor Name:Krka, d.d., Novo mesto
    Full Title: Comparison of the efficacy and safety of the fixed-dose combination of xylometazoline and dexpanthenol in SeptaNazal® and xylometazoline in nasal congestion in patients after surgery in the nose an...
    Medical condition: Nasal congestion in patients after nasal surgery or nasal cavities surgery and in patients with acute rhinitis
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004855 10028736 Nasal congestion and inflammations HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SI (Completed) HR (Completed)
    Trial results: View results
    EudraCT Number: 2020-001721-31 Sponsor Protocol Number: SPON-AK-0420 Start Date*: 2020-05-01
    Sponsor Name:Hampshire Hospitals NHS TRust
    Full Title: Can a sinus rinse and mouth wash reduce viral load in COVID-19 positive individuals?
    Medical condition: Covid-19
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10061986 SARS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2011-004183-29 Sponsor Protocol Number: DERC-03 Start Date*: 2014-06-27
    Sponsor Name:Dermal Laboratories
    Full Title: A randomised, placebo-controlled trial to investigate the effectiveness of an antimicrobial product in the elimination of Staphylococcus aureus colonisation from the anterior nares of adult subject...
    Medical condition: Nasal colonisation with Staphylococcus aureus
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004862 10069719 Bacterial colonisation LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2022-002944-40 Sponsor Protocol Number: CHUB-Methoxyflurane Start Date*: 2023-02-14
    Sponsor Name:CHU Brugmann
    Full Title: Prospective monocentric randomized study: use of Methoxyflurane via a mouth-nose mask versus inhaler in the management of pain following limb trauma
    Medical condition: Acute limb trauma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2005-005207-42 Sponsor Protocol Number: 2005079 Start Date*: 2005-12-29
    Sponsor Name:Procter & Gamble Technical Centres Limited
    Full Title: A study to assess the efficacy of a combination of natural plant extracts in natural colds.
    Medical condition: Common Cold (nasopharyngitis), Upper Respiratory Tract Infection
    Disease: Version SOC Term Classification Code Term Level
    8.0 10028810 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-000893-12 Sponsor Protocol Number: 8302 Start Date*: 2017-08-31
    Sponsor Name:The Newcastle Upon Tyne Hospitals NHS Foundation Trust
    Full Title: Nasal Airway Obstruction Study
    Medical condition: Deviated Nasal Septum
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10034383 Perennial rhinitis LLT
    20.1 100000004870 10039776 Seasonal allergic rhinitis LLT
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10028756 Nasal polyps PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2016-004827-22 Sponsor Protocol Number: BM41-VD3 Start Date*: 2017-07-25
    Sponsor Name:Academic Medical Center
    Full Title: A randomized, double-blind, placebo-controlled, double-dummy study to determine the safety/tolerability of a simultaneous subcutaneous treatment of BM41 and vitamin D 3 in patients with moderate to...
    Medical condition: moderate to severe allergic rhinitis/rhino-conjunctivitis caused by birch pollen (with or without concomitant mild to moderate persistent asthma)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-003846-26 Sponsor Protocol Number: C-05-69 Start Date*: 2017-11-19
    Sponsor Name:Alcon Research Ltd
    Full Title: Safety Study of Olopatadine Nasal Spray
    Medical condition: perennial allergic rhinitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004855 10034382 Perennial allergic rhinitis LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2005-002805-21 Sponsor Protocol Number: D2530C00011 Start Date*: 2005-09-25
    Sponsor Name:AstraZeneca AB
    Full Title: A randomized, double-blind, placebo controlled, three-way crossover study exploring the efficacy of AZD3778 compared with placebo and an oral antihistamine (loratadine) in a model of seasonal aller...
    Medical condition: This is a Phase II trial (Proof of Principle) in volunteer rhinitis subjects utilising a seasonal model of rhinitis and challenge agent
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2013-001803-35 Sponsor Protocol Number: ACT12340 Start Date*: 2013-07-31
    Sponsor Name:Sanofi-aventis recherche et développement
    Full Title: A Randomized, Double-Blind, Phase 2, Placebo Controlled, 2 Arm Study To Evaluate Dupilumab In Patients With Bilateral Nasal Polyposis And Chronic Symptoms Of Sinusitis
    Medical condition: Nasal polyps
    Disease: Version SOC Term Classification Code Term Level
    16.1 10038738 - Respiratory, thoracic and mediastinal disorders 10028756 Nasal polyps PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed) SE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2013-002414-12 Sponsor Protocol Number: 12082.101 Start Date*: Information not available in EudraCT
    Sponsor Name:PARI Pharma GmbH
    Full Title: A randomised, open, controlled pilot study to investigate the efficacy and safety of Buparid/PARI SINUS versus Budes® Nasal Spray in the therapy of Chronic Rhinosinusitis (CRS) with polyposis nasi ...
    Medical condition: Chronic Rhinosinusitis (CRS) with polyposis nasi
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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