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Clinical trials for Objective

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44351   clinical trials with a EudraCT protocol, of which   7378   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    14,138 result(s) found for: Objective. Displaying page 1 of 707.
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    EudraCT Number: 2007-000357-54 Sponsor Protocol Number: UniversityHospitalGrenoble Start Date*: 2007-07-08
    Sponsor Name:UniversityHospitalGrenoble
    Full Title: Chemotherapy of first line "reinforced" for cancers of the colonist and the rectum with hepatic and/or pulmonary metastases potentially résécables: Strong association FOLFIRI and ERBITUX
    Medical condition: cancers of the colonist and the rectum
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-000117-39 Sponsor Protocol Number: A2301 Start Date*: 2011-06-14
    Sponsor Name:Ixodes AG.
    Full Title: A Phase 3 randomized, double-blind, placebo-controlled study of SHB004 (10% topical azithromycin) administered locally twice daily for three consecutive days for the prevention of Borreliosis in su...
    Medical condition: Lyme borreliosis
    Disease: Version SOC Term Classification Code Term Level
    15.1 100000004862 10067559 Lyme borreliosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2017-003250-16 Sponsor Protocol Number: MTI-110 Start Date*: 2017-12-11
    Sponsor Name:Menlo Therapeutics Inc.
    Full Title: A Randomized, Double-Blind, Placebo-Controlled Study Of The Efficacy, Safety, And Tolerability Of Serlopitant For The Treatment Of Refractory Chronic Cough
    Medical condition: Refractory Chronic Cough
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004855 10066656 Chronic cough LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-003966-42 Sponsor Protocol Number: 71691 Start Date*: 2021-02-16
    Sponsor Name:Erasmus MC
    Full Title: Adjuvant hepatic arterial infusion pump chemotherapy after repeat hepatectomy for patients with recurrent colorectal liver metastases without a history of extrahepatic disease – a phase II study
    Medical condition: LIver recurrence after hepatectomy for CRLM.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-004504-31 Sponsor Protocol Number: 0822-031 Start Date*: 2008-09-16
    Sponsor Name:Merck Sharp & DOhme (Sweden) AB
    Full Title: A Phase III Randomized, Placebo-Controlled Study to Evaluate the Effect of Odanacatib (MK-0822) on Bone Mineral Density (BMD) and Overall Safety, and to Estimate the Effect of Odanacatib (MK-0822) ...
    Medical condition: low BMD (bone mineral density)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10032364 Other osteoporosis LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: SE (Prematurely Ended) FR (Completed) DK (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-001481-14 Sponsor Protocol Number: TAX-001 Start Date*: 2005-06-22
    Sponsor Name:University Hospital Tübingen
    Full Title: LOCAL-TAX Trial: Local intracoronary administration of Paclitaxel after stent implantation for prevention of restenosis in comparison with stent implantation alone and with implantation of a Paclit...
    Medical condition: coronary heart disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-002093-60 Sponsor Protocol Number: BCX1777-203 Start Date*: 2007-10-05
    Sponsor Name:BioCryst Pharmaceuticals, Inc.
    Full Title: Single agent phase II study of Forodesine (BCX1777) in the treatment of cutaneous T-Cell Lymphoma
    Medical condition: Primary cutaneous T-cell lymphomas (CTCLs)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028508 Mycosis fungoides/Sezary syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) GB (Completed) DE (Completed) FI (Completed) IT (Completed) ES (Completed) AT (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2014-002017-28 Sponsor Protocol Number: LinaclotideRectumColon Start Date*: 2014-07-16
    Sponsor Name:KULEUVEN
    Full Title: ROLE OF THE TYPE AND SITE OF DISTENSION IN THE EVALUATION OF DRUGS EFFICACY IN MODULATING THE SENSORY AND MOTOR RESPONSE OF THE DESCENDING COLON AND THE RECTUM IN MAN
    Medical condition: HEALTHY SUBJECTS AND PATIENTS WITH IRRITABLE BOWEL SYNDROME
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2006-000395-32 Sponsor Protocol Number: 2006001 Start Date*: 2006-03-29
    Sponsor Name:King's College London
    Full Title: The effect of COX-2 Inhibition on Reducing Central Sensitisation of Pain in Osteoarthritis
    Medical condition: Osteoarthritis of the knee
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-002897-31 Sponsor Protocol Number: 1453 Start Date*: 2006-04-04
    Sponsor Name:North Bristol NHS Trust
    Full Title: Objective assessment of attention difficulties in adults with Attention-Deficit Hyperactivity Disorder (ADHD)
    Medical condition: Attention-Deficit Hyperactivity Disorder (ADHD) in Adults
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-004701-24 Sponsor Protocol Number: D4200C00097 Start Date*: 2012-03-27
    Sponsor Name:AstraZeneca AB
    Full Title: An International, Randomised, Double-Blind, Two-Arm Study To Evaluate The Safety And Efficacy Of Vandetanib 150 And 300mg/Day In Patients With Unresectable Locally Advanced Or Metastatic Medullary ...
    Medical condition: Unresectable locally advanced or metastatic medullary thyroid cancer
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004864 10027105 Medullary thyroid cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) NL (Completed) IT (Completed) PL (Completed) GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-020081-22 Sponsor Protocol Number: R&D 2185 Start Date*: 2011-02-08
    Sponsor Name:North Bristol NHS Trust
    Full Title: The administration of Parathyroid hormone affects functional recovery from pertrochanteric fractured neck of femur: A prospective randomised comparative pilot study with blinded objective functiona...
    Medical condition: Osteoporotic or low energy pertrochanteric hip fractures
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2014-001314-25 Sponsor Protocol Number: KIANANDR140701 Start Date*: 2015-03-10
    Sponsor Name:Karolinska Institutet
    Full Title: The effect of on demand versus continuous use of proton pump inhibitors on reflux symptoms, quality of life and self-rated health in patients with gastro-oesophageal reflux disease
    Medical condition: Gastrooesophageal reflux disease
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: View results
    EudraCT Number: 2015-005064-42 Sponsor Protocol Number: AF219-012 Start Date*: 2016-02-26
    Sponsor Name:Afferent Pharmaceuticals, Inc.
    Full Title: A 12-Week Study to Assess the Efficacy and Safety of AF-219 in Subjects with Treatment Refractory Chronic Cough
    Medical condition: Chronic Cough
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-001289-14 Sponsor Protocol Number: MIT-Do001-C301 Start Date*: 2020-02-05
    Sponsor Name:Estetra SRL
    Full Title: A Randomized Double-blind Placebo Controlled Phase 3 Trial to evaluate the Efficacy and Safety of Estetrol for the Treatment of Moderate to Severe Vasomotor Symptoms in Postmenopausal Women (E4Comf...
    Medical condition: Moderate to Severe Vasomotor Symptoms (VMS) in Postmenopausal Women
    Disease: Version SOC Term Classification Code Term Level
    21.0 10047065 - Vascular disorders 10020407 Hot flashes LLT
    Population Age: Adults Gender: Female
    Trial protocol: PL (Completed) GB (GB - no longer in EU/EEA) SK (Completed) HU (Completed) LT (Completed) CZ (Completed) ES (Completed) IT (Completed) RO (Completed)
    Trial results: View results
    EudraCT Number: 2009-014799-23 Sponsor Protocol Number: PH-L19IL2-03/09 Start Date*: 2010-02-04
    Sponsor Name:Philogen S.p.A
    Full Title: A phase II study of intratumoral application of L19IL2 in patients with stage III/IV melanoma
    Medical condition: Cancer- Patients with histopathologically-proven malignant melanoma with presence of measurable and injectable dermal or subcutaneous metastases either in clinical stage III or stage IV
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10025671 Malignant melanoma stage IV PT
    14.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10025670 Malignant melanoma stage III PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) IT (Completed) AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-002806-10 Sponsor Protocol Number: SOBI003-001 Start Date*: Information not available in EudraCT
    Sponsor Name:Swedish Orphan Biovitrum AB (publ)
    Full Title: An open, non-controlled, parallel, ascending multiple-dose, multicenter study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of SOBI003 in pediatric MPS IIIA patients
    Medical condition: Mucopolysaccharidosis Type IIIA or Sanfilippo Syndrome
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004850 10028094 Mucopolysaccharidosis IH LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2021-003170-31 Sponsor Protocol Number: QHD00027 Start Date*: 2021-08-16
    Sponsor Name:Cardiovascular Non-Invasive Imaging Research Laboratory, Department of Cardiology, Herlev and Gentofte Hospital
    Full Title: Feasibility of Randomizing Danish Citizens Aged 65-79 Years to High-Dose Quadrivalent Influenza Vaccine vs. Standard-Dose Quadrivalent Influenza Vaccine in a Pragmatic Registry-Based Setting
    Medical condition: Prevention of influenza infection in adults aged 65-79 years
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10022000 Influenza PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2020-000630-17 Sponsor Protocol Number: MER-XMT-1536-1 Start Date*: 2021-09-21
    Sponsor Name:Mersana Therapeutics, Inc.
    Full Title: A Phase 1b/2, First-in-Human, Dose Escalation and Expansion Study of XMT-1536 In Patients with Solid Tumors Likely to Express NaPi2b
    Medical condition: High grade serous ovarian cancer or non-small cell lung cancer (NSCLC), adenocarcinoma subtype
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10033128 Ovarian cancer PT
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061873 Non-small cell lung cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) NO (Completed) LT (Completed) CZ (Completed) HU (Completed) BG (Completed) FI (Completed) PL (Completed) DK (Completed) IT (Completed) AT (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2009-012582-64 Sponsor Protocol Number: 337/09 Start Date*: 2009-07-29
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Treatment with bevacizumab and irinotecan in patients with recurrent or refractory high grade glioma after conventional treatment.
    Medical condition: high grade glioma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10065443 Malignant glioma LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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