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Clinical trials for Old age

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    2,560 result(s) found for: Old age. Displaying page 1 of 128.
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    EudraCT Number: 2012-001458-24 Sponsor Protocol Number: VAC-264 Start Date*: 2012-09-03
    Sponsor Name:RIVM
    Full Title: Cross-sectional surveillance study on pneumococcal serotypes and other pathogens in nasopharyngeal samples from infants and parents performed 6.5 years after introduction of pneumococcal vaccinatio...
    Medical condition: The study investigates the presence of nasopharyngeal vaccine- and non-vaccine pneumococcal serotypes in 11- and 24-month-old infants and parents, 6.5 years after implementation of a pneumococcal v...
    Disease:
    Population Age: Infants and toddlers, Children, Under 18, Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2009-017739-17 Sponsor Protocol Number: ISI-2009LGE Start Date*: 2010-02-12
    Sponsor Name:Charité
    Full Title: Assessment of myocardial viability in MRI: Comparison of Late Gadolinium Enhancement with Gadovist vs. Magnevist vs. Dotarem
    Medical condition: Patients with a history of chronic myocardial infarction
    Disease: Version SOC Term Classification Code Term Level
    12.1 10028596 Myocardial infarction LLT
    12.1 10028598 Myocardial infarction old LLT
    12.1 10028599 Myocardial infarction old healed LLT
    12.1 10030272 Old myocardial infarction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2024-000461-24 Sponsor Protocol Number: LPS15677 Start Date*: 2024-12-18
    Sponsor Name:Genzyme
    Full Title: A Single Arm, Prospective, Open-label, Multi-center Study to Evaluate Efficacy and Safety in Chinese Patients with Late Onset Pompe Disease with One Year Alglucosidase Alfa Treatment
    Medical condition: Pompe's disease
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2011-004931-30 Sponsor Protocol Number: V72P12E2 Start Date*: 2012-10-10
    Sponsor Name:Novartis Vaccines and Diagnostics S.r.l.
    Full Title: A Phase 3, Open Label, Multi-Center, Extension Study to Assess Antibody Persistence and Response to a Third or Fift Dose of Novartis Meningococcal B Recombinant Vaccine in 4-Year-Old Children Who ...
    Medical condition: Prevention of meningococcal disease caused by serogroup B Neisseria meningitidis by evaluating the Antibody persistence in 4-year old healthy children who previously received the Novartis meningoco...
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed) IT (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2010-019420-31 Sponsor Protocol Number: no sponser Start Date*: 2011-04-22
    Sponsor Name:
    Full Title: ‘The influence of MAC values and behaviour of a child on emergence delirium after sevoflurane anaesthesia’
    Medical condition: ‘Emergence delirium’ (ED) is described as a mental disorder during recovery from general anaesthesia. After the introduction of new inhalation anaesthetics such as sevoflurane, this phenomenon agai...
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-002635-15 Sponsor Protocol Number: 15-06 Start Date*: 2016-07-28
    Sponsor Name:VU Medical Center
    Full Title: Study to Identify Factors associated with Resilience to Clinical Dementia at Old Age
    Medical condition: The protective factors of Alzheimer's disease in subjects aged 90 years and older
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2022-004181-37 Sponsor Protocol Number: B9371039 Start Date*: 2023-02-03
    Sponsor Name:Pfizer Inc.
    Full Title: A PHASE 3, SINGLE-ARM, OPEN-LABEL STUDY TO EVALUATE THE IMMUNOGENICITY, SAFETY, AND TOLERABILITY OF A TICK-BORNE ENCEPHALITIS VACCINE IN HEALTHY JAPANESE PARTICIPANTS 1 YEAR OF AGE AND OLDER
    Medical condition: Active immunization to prevent tick borne encephalitis (TBE)
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2020-000976-40 Sponsor Protocol Number: ION373-CS1 Start Date*: Information not available in EudraCT
    Sponsor Name:Ionis Pharmaceuticals, Inc
    Full Title: A Phase 1-3, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Intrathecally Administered ION373 in Patients with Alexand...
    Medical condition: Alexander Disease
    Disease: Version SOC Term Classification Code Term Level
    22.1 10010331 - Congenital, familial and genetic disorders 10083059 Alexander disease PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) NL (Trial now transitioned) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-001314-15 Sponsor Protocol Number: V503‐010 Start Date*: 2014-01-20
    Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
    Full Title: A Phase III Clinical Trial to Study the Tolerability and Immunogenicity of a 2-dose regimen of V503, a Multivalent Human Papillomavirus (HPV) L1 Virus-Like Particle (VLP) Vaccine, administered in P...
    Medical condition: This study is to study the tolerability and immunogenicity of V503, specific conditions (effiecacy endpoints) are not being investigated in this study.
    Disease:
    Population Age: Children, Under 18, Adults Gender: Male, Female
    Trial protocol: CZ (Completed) NO (Completed) DK (Completed) ES (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2010-022882-80 Sponsor Protocol Number: 2010.621 Start Date*: 2010-09-17
    Sponsor Name:Hospices Civils de Lyon
    Full Title: EXPAND ID. Analyse de la réponse immunitaire à la vaccination anti-grippe chez les sujets âgés de 65 ans et plus.
    Medical condition: Sujets de 65 ans et plus, ayant été vaccinés contre la grippe saisonnière
    Disease: Version SOC Term Classification Code Term Level
    12.1 10014348 Elderly LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-005030-54 Sponsor Protocol Number: MK-0991-042 Start Date*: 2015-02-24
    Sponsor Name:Merck & Co., Inc.
    Full Title: A Multicenter, Open, Sequential Dose-Escalation Study to Investigate the Safety, Tolerability, and Pharmacokinetics of 2 Separate Doses of Caspofungin Acetate in Children Between the Ages of 3 to 2...
    Medical condition: Neutropenic immunosuppressed
    Disease:
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2022-000156-11 Sponsor Protocol Number: S65914 Start Date*: 2022-02-25
    Sponsor Name:KU Leuven
    Full Title: Oxytocin and the development of attachment: Looking beyond the expected?
    Medical condition: General healthy population children (ages 8 - 13 years old).
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-004458-25 Sponsor Protocol Number: RVX01C Start Date*: Information not available in EudraCT
    Sponsor Name:Sanofi Pasteur MSD
    Full Title: Antibody persistence in 11 to 13-year-old children previously vaccinated at 6 years old with either REVAXIS or DT Polio, and immune response to a booster dose of TETRAVAC-ACELLULAIRE
    Medical condition: Persistence of antibody against diphtheria, tetanus and poliomyelitis in 11 to 13-year-old children who received either REVAXIS or DT Polio at 6 year of age, and immune response to TETRAVAC-ACELLUL...
    Disease: Version SOC Term Classification Code Term Level
    14.0 10042613 - Surgical and medical procedures 10054175 Polio immunisation PT
    14.0 10042613 - Surgical and medical procedures 10054129 Diphtheria immunisation PT
    14.0 10042613 - Surgical and medical procedures 10069577 Pertussis immunisation PT
    14.0 10042613 - Surgical and medical procedures 10054131 Tetanus immunisation PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: View results
    EudraCT Number: 2015-005185-34 Sponsor Protocol Number: IPV29 Start Date*: 2015-11-19
    Sponsor Name:Sanofi Pasteur China
    Full Title: Safety study of IMOVAX Polio in selected cities in China, an observational post marketing study
    Medical condition: Poliomyelitis
    Disease:
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2020-000840-75 Sponsor Protocol Number: D4920C00002 Start Date*: 2020-09-15
    Sponsor Name:AstraZeneca AB
    Full Title: A Phase IIB, Randomized, Double blinded, Placebo controlled, Parallel group Study to Evaluate the Efficacy and Safety of MEDI6570 in Participants with a Prior Myocardial Infarction, Persistent Infl...
    Medical condition: Myocardial Infarction (MI)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10030272 Old myocardial infarction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) CZ (Completed) PL (Completed) NL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-004160-22 Sponsor Protocol Number: LUMC_IEMO80PLUS_1.0 Start Date*: 2013-06-18
    Sponsor Name:Leiden University Medical Center
    Full Title: IEMO 80-plus thyroid trial
    Medical condition: Subclinical hypothyroidism
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2016-001764-11 Sponsor Protocol Number: PTC124-GD-030-DMD Start Date*: 2020-01-21
    Sponsor Name:PTC Therapeutics, Inc.
    Full Title: A Phase 2 Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Ataluren (PTC124®) in Patients Aged ≥2 to <5 Years Old With Nonsense Mutation Dystrophinopathy
    Medical condition: nonsense mutation dystrophinopathy
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10013801 Duchenne muscular dystrophy PT
    20.0 10010331 - Congenital, familial and genetic disorders 10059117 Becker's muscular dystrophy PT
    Population Age: Children, Under 18 Gender: Male
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2008-004972-37 Sponsor Protocol Number: NVI-249 Start Date*: 2008-09-23
    Sponsor Name:Netherlands Vaccine Institute
    Full Title: Effects of Routine Infant Vaccination With the 7-valent Pneumococcal Conjugate Vaccine on Nasopharyngeal Colonization with Streptococcus pneumoniae in Children and Parents in the Netherlands
    Medical condition: This study investigates the influence of the Prevenar® vaccination schedule in the NIP on colonisation with vaccine- and non-vaccine serotypes in the third year after implementation of Prevenar® i...
    Disease:
    Population Age: Infants and toddlers, Children, Under 18, Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2017-003796-58 Sponsor Protocol Number: NAC-GED-0507-ACN-02-17 Start Date*: 2017-12-13
    Sponsor Name:PPM SERVICES S.A.
    Full Title: AN OPEN LABEL CLINICAL STUDY TO EVALUATE THE LONG-TERM DERMAL SAFETY PROFILE OF 12-WEEKS TOPICAL ADMINISTRATION OF N-ACETYL-GED-0507-34-LEVO GEL 5% IN PATIENTS WITH FACIAL ACNE
    Medical condition: FACIAL ACNE
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004858 10000519 Acne vulgaris LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2021-003191-14 Sponsor Protocol Number: 21CH135 Start Date*: 2021-08-16
    Sponsor Name:CHU SAINT-ETIENNE
    Full Title: Cohort assessing the immunogenicity and the safety of the COVID-19 Vaccine Janssen in healthy volunteers based on 3 age groups: 65 years or older - 55 to 65 years - 18 to 45 years - Covicompare-Jan...
    Medical condition: volunteers
    Disease: Version SOC Term Classification Code Term Level
    23.1 10042613 - Surgical and medical procedures 10084465 COVID-19 vaccination LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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