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Clinical trials for Older's classification

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    337 result(s) found for: Older's classification. Displaying page 1 of 17.
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    EudraCT Number: 2017-001939-38 Sponsor Protocol Number: NIVINIHO Start Date*: 2018-04-18
    Sponsor Name:LYSARC
    Full Title: A prospective phase II study of nivolumab alone, or in combination with vinblastin in patients aged 61 years and older, with classical Hodgkin Lymphoma and coexisting medical conditions
    Medical condition: patients aged 61 years and older, with classical Hodgkin lymphoma and coexisting medical conditions
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004864 10080208 Classical Hodgkin lymphoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2006-004434-32 Sponsor Protocol Number: PREPOD Start Date*: 2007-02-06
    Sponsor Name:Technische Universität München, Fakultät für Medizin, Klinikum rechts der Isar
    Full Title: Prevention of postoperative delirium with donepezil
    Medical condition: Postoperative delirium
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-001818-16 Sponsor Protocol Number: LT-CLL-001 Start Date*: 2007-07-05
    Sponsor Name:Vilnius University Hospital Santariskiu Clinics
    Full Title: Phase II Study of High-dose Methylprednisolone and Rituximab in Previously Treated Patients with High Risk Chronic B Lymphocytic Leukemia
    Medical condition: Treated high-risk chronic B lymphocytic leukemia.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003947 B-Lymphocytic, CLL (Kiel Classification) recurrent LLT
    9.1 10003948 B-Lymphocytic, CLL (Kiel Classification) refractory LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001284-24 Sponsor Protocol Number: BGB-3111-214 Start Date*: 2019-04-01
    Sponsor Name:BeiGene, Ltd.
    Full Title: A Phase 2, Open-label Study of Zanubrutinib (BGB-3111) in Patients with Relapsed or Refractory Marginal Zone Lymphoma
    Medical condition: Relapsed or Refractory Marginal Zone Lymphoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10076596 Marginal zone lymphoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) FR (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2021-002730-16 Sponsor Protocol Number: GLS27-005 Start Date*: 2021-10-25
    Sponsor Name:GeneOne Life Science Inc.
    Full Title: Safety, Tolerability, Efficacy and Dose Response of GLS-1027 in the Prevention of Severe Pneumonitis caused by SARS-CoV-2 Infection
    Medical condition: Patients with SARS-CoV-2 infection
    Disease: Version SOC Term Classification Code Term Level
    23.0 10021881 - Infections and infestations 10084268 COVID-19 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-023205-35 Sponsor Protocol Number: LT-CLL-2s Start Date*: 2011-02-07
    Sponsor Name:Vilnius University Hospital Santariskiu Clinics
    Full Title: Study of Rituximab in Addition to Glucocorticoid in Pretreated Elderly or Unfit Patients with Chronic B Lymphocytic Leukemia
    Medical condition: Treated Elderly Patients with Chronic B Lymphocytic Leukemia or patients with underlying pathology
    Disease: Version SOC Term Classification Code Term Level
    15.1 100000004864 10003948 B-Lymphocytic, CLL (Kiel Classification) refractory LLT
    15.1 100000004864 10003947 B-Lymphocytic, CLL (Kiel Classification) recurrent LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-003185-33 Sponsor Protocol Number: INRCA-02-2011 Start Date*: 2011-10-13
    Sponsor Name:ISTITUTO NAZIONALE DI RICOVERO E CURA PER ANZIANI IRCCS
    Full Title: Prospective, controlled, randomized, blind study to evaluate the effects of intramuscular-paravertebral injections of an oxygen-ozone (O2-O3) mixture in patients with lumbar pain aged 65 or older
    Medical condition: subjects aged 65 or older with lumbar pain and discopathy for at least 6 weeks
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10028395 Musculoskeletal and connective tissue disorders SOC
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-001401-25 Sponsor Protocol Number: QHD00012 Start Date*: 2019-09-27
    Sponsor Name:Sanofi Pasteur Inc.
    Full Title: Relative Effectiveness of a High-Dose Quadrivalent Influenza Vaccine versus a Standard-Dose Quadrivalent Influenza Vaccine in Subjects 65 Years of Age and Older
    Medical condition: Prevention of influenza infection in adults from 65 years of age and older
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10022000 Influenza PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-003932-40 Sponsor Protocol Number: 1138.11 Start Date*: 2009-03-26
    Sponsor Name:Boerhinger Ingelheim Pharma GmbH & Co.KG
    Full Title: A 12-week, double-blind, randomised, placebo-controlled, multicentre trial to evaluate efficacy and tolerability of Antistax® film-coated tablets, 720mg/day orally, in male and female patients suff...
    Medical condition: chronic venous insufficiency
    Disease: Version SOC Term Classification Code Term Level
    9.1 10066682 Chronic venous insufficiency LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2018-001778-12 Sponsor Protocol Number: HUGTP-CIR-FIBRIN-GLUE-01 Start Date*: 2019-04-15
    Sponsor Name:Fundació Institut de Recerca en Ciències de la Salut Germans Trias i Pujol
    Full Title: USE OF A FIBRINE ADHESIVE TO REDUCE THE DEHISCENCE OF ESOFAGOYEYUNAL ANASTOMOSIS IN TOTAL GASTRECTOMIES BY CANCER: RANDOMIZED AND MULTICENTRIC STUDY.
    Medical condition: The dehiscence of the esophagojejunal anastomosis after a total gastrectomy in patients with gastric adenocarcinoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10058439 Esophageal anastomosis LLT
    20.0 100000004856 10013121 Diseases of esophagus LLT
    20.1 100000004863 10075515 Stoma site leakage LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-003620-20 Sponsor Protocol Number: NL71296-041-19 Start Date*: 2021-04-21
    Sponsor Name:University Medical Center Utrecht
    Full Title: Tolerogenic dendritic cell therapy for rheumatoid arthritis.
    Medical condition: Rheumatoid Arthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-015941-22 Sponsor Protocol Number: TRM-1 Cervical Cancer Start Date*: 2010-01-05
    Sponsor Name:University Medical Center Groningen
    Full Title: A phase 1b/2 study with the agonistic TRAIL-R1 antibody, mapatumumab, in combination with cisplatin and radiotherapy as a first line therapy in patients with advanced cervical cancer
    Medical condition: Patients with stage IB2, IIA2, IIB, III, and IVA cervical cancer, according to the FIGO classification.
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-005966-35 Sponsor Protocol Number: KKS/INNERE_A/AML2006 Start Date*: 2006-07-24
    Sponsor Name:Universitätsklinikum Münster
    Full Title: A double-blind, placebo-controlled, randomized, multi-center phase II trial to assess the efficacy of Sorafenib added to standard primary therapy in elderly patients with newly diagnosed AML
    Medical condition: Patients older than 60 years with newly diagnosed acute myeloid leukemia (AML)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2019-001361-33 Sponsor Protocol Number: CYP-CLI-P2-01 Start Date*: 2020-07-27
    Sponsor Name:Cynata Therapeutics Limited
    Full Title: A Randomised, Double-blind, Placebo-controlled Phase 2 Study to Investigate the Efficacy, Safety and Tolerability of CYP-002 in Adults with Critical Limb Ischaemia who are Unsuitable for Revascular...
    Medical condition: Critical Limb Ischaemia
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004866 10058069 Critical limb ischemia LLT
    21.1 100000004866 10058072 Critical limb ischaemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2023-000010-18 Sponsor Protocol Number: WATERLAND Start Date*: 2023-03-23
    Sponsor Name:Enrique de Madaria
    Full Title: Normal saline versus lactated Ringer’s solution for acute pancreatitis resuscitation, an open-label multicenter randomized controlled trial: the WATERLAND trial
    Medical condition: Acute pancreatitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10017947 - Gastrointestinal disorders 10033647 Pancreatitis acute PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-002834-36 Sponsor Protocol Number: Retro-001 Start Date*: 2012-09-13
    Sponsor Name:UMCG
    Full Title: Evaluation of the effects of the addition of atropine during propofol/remifentanil induction of anesthesia on hemodynamics, microvascular blood flow and tissue oxygenenation in patients undergoing ...
    Medical condition: ophthalmic surgery
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-004320-13 Sponsor Protocol Number: AMLSG 06-04 Start Date*: 2005-08-29
    Sponsor Name:Universitätsklinikum Ulm / University Clinical Center Ulm
    Full Title: RANDOMIZED PHASE III-STUDY ON VALPROIC ACID IN COMBINATION WITH ALL-TRANS RETINOIC ACID, STANDARD INDUCTION- AND CONSOLIDATION THERAPY IN OLDER PATIENTS WITH NEWLY DIAGNOSED ACUTE MYELOID LEUKEMIA
    Medical condition: newly diagnosed acute myeloid leukemia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2020-000135-47 Sponsor Protocol Number: 21/103 Start Date*: 2021-11-02
    Sponsor Name:Hospital Universitario Fundación Alcorcón
    Full Title: Analgesic efficacy of erector spinae plane block in lumbar spine surgery: a prospective, randomized and double blind study.
    Medical condition: The analgesic efficacy of erector spinae plane block in lumbar spine surgery. Infiltration of local anesthetic in this plane may lower postoperative pain.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-000863-34 Sponsor Protocol Number: NL58590.078.16 Start Date*: 2017-12-05
    Sponsor Name:
    Full Title: Curing chronic wounds with fibrin
    Medical condition: non-healing skin wounds
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-004713-91 Sponsor Protocol Number: ROPISPINE Start Date*: 2015-02-09
    Sponsor Name:Universitair Ziekenhuis Brussel
    Full Title: Epidural ropivacaine as part of a multimodal postoperative pain treatment following thoracolumbar spinal fusion surgery.
    Medical condition: Spine Surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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