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Clinical trials for Osteochondritis

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44363   clinical trials with a EudraCT protocol, of which   7387   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    13 result(s) found for: Osteochondritis. Displaying page 1 of 1.
    EudraCT Number: 2006-004817-16 Sponsor Protocol Number: MACI00206 Start Date*: 2008-01-23
    Sponsor Name:Genzyme Europe B.V.
    Full Title: A Prospective, Randomized, Open-Label, Parallel-Group, Multicenter Study to Demonstrate the Superiority of Matrix-induced Autologous Chondrocyte Implantation (MACI® implant) versus Arthroscopic Mi...
    Medical condition: Symptomatic Articular Cartilage Defects of the Femoral Condyle including the Trochlea. osteochondritis dissecans lesions that do not require a bone graft.
    Disease: Version SOC Term Classification Code Term Level
    13.1 10028395 - Musculoskeletal and connective tissue disorders 10031231 Osteochondritis dissecans LLT
    13.1 10022117 - Injury, poisoning and procedural complications 10007705 Cartilage damage LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed) CZ (Completed) SE (Completed) NL (Completed) PL (Completed) DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-016970-33 Sponsor Protocol Number: MACI00809 Start Date*: 2011-03-17
    Sponsor Name:Genzyme Europe BV
    Full Title: An Extension Protocol for Participants of Genzyme-Sponsored Prospective, Randomized, Open-Label, Parallel-Group, Multicenter Study of Matrix-Induced Autologous Chondrocyte Implantation (MACI® impl...
    Medical condition: Symptomatic Articular Cartilage Defects of the Femoral Condyle including the Trochlea. Osteochondritis dissecans lesions that do not require a bone graft.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10031231 Osteochondritis dissecans LLT
    14.1 10022117 - Injury, poisoning and procedural complications 10007705 Cartilage damage LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed) CZ (Completed) GB (Completed) SE (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2009-016751-22 Sponsor Protocol Number: ABR30311 Start Date*: 2010-04-01
    Sponsor Name:AMC, divisie Psychiatrie
    Full Title: A double blind, placebo controlled study of memantine in patients with obsessive-compulsive disorder.
    Medical condition: Obsessive-compulsive disorder (OCD)
    Disease: Version SOC Term Classification Code Term Level
    12.0 10030029 OCD LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-003481-18 Sponsor Protocol Number: CART.III. Start Date*: 2008-11-17
    Sponsor Name:TBF
    Full Title: PHASE III PROTOCOL COMPARING A MICROFRACTURE TREATMENT TO A CARTIPATCH® CHONDROCYTE GRAFT TREATMENT IN FEMORAL CONDYLE LESIONS
    Medical condition: Femoral condyles single lesion from trauma or osteochondritis dissequans with invalidant signs
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2015-000072-99 Sponsor Protocol Number: 05012015 Start Date*: 2015-05-06
    Sponsor Name:Ilkka Helenius
    Full Title: EFFECT OF PREGABALIN ON IMMEDIATE POSTOPERATIVE AND LONGTERM PAIN AND SPINAL MONITORING IN CHILDREN UNDERGOING INSTRUMENTED SPINAL SURGERY. A placebo-controlled randomized clinical trial
    Medical condition: Idiopatic scoliosis
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004859 10039594 Scheuermann's disease LLT
    18.0 100000004859 10039723 Scoliosis (and kyphoscoliosis), idiopathic LLT
    18.0 100000004859 10049007 Spondylolisthesis NOS LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-002817-22 Sponsor Protocol Number: AAG-G-H-1624 Start Date*: 2017-02-09
    Sponsor Name:TETEC Tissue Engineering Technologies - AG
    Full Title: Prospective, Multicenter, Single-arm Phase III Clinical Trial to Evaluate the Efficacy and Safety of NOVOCART® Inject plus in the Treatment of Cartilage Defects of the Knee
    Medical condition: Repair of cartilage defects of the knee (medial or lateral femoral condyle or tibial plateau, trochlea or patella) caused by traumatic events or osteochondritis dissecans (defect size is ≥ 4 and ≤...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000009764 10007702 Cartilage biopsy LLT
    20.0 10042613 - Surgical and medical procedures 10052913 Cartilage operation PT
    20.0 100000019132 10007705 Cartilage damage LLT
    20.0 100000022571 10057104 Cartilage repair LLT
    20.0 10042613 - Surgical and medical procedures 10064112 Cartilage graft PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) CZ (Completed) DE (Completed) PL (Completed) LT (Completed)
    Trial results: View results
    EudraCT Number: 2010-020513-87 Sponsor Protocol Number: Q03-09-01 Start Date*: 2010-09-02
    Sponsor Name:FIDIA
    Full Title: A randomized, placebo-controlled, double-blind study on the intensity and duration of efficacy of sodium hyaluronate therapy (500-730 KDa) (HYALGAN) in the conservative treatment of Achilles tendin...
    Medical condition: Achilles tendinopathy.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000433 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-021869-73 Sponsor Protocol Number: 33178 Start Date*: 2011-01-25
    Sponsor Name:OrthoCell Pty Ltd
    Full Title: The value of Autologous Tenocyte Implantation in patients with chronic Achilles tendinopathy: a double-blind randomised clinical trial
    Medical condition: Chronic midportion Achilles tendinopathy
    Disease: Version SOC Term Classification Code Term Level
    12.1 10000433 Achilles tendinitis LLT
    12.1 10000435 Achilles tendon injury LLT
    12.1 10048602 Achilles tendon discomfort LLT
    12.1 10050471 Achilles tendon pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-002601-35 Sponsor Protocol Number: ACT-2017-01 Start Date*: 2018-07-02
    Sponsor Name:PrimeCell Advanced Therapy a.s.
    Full Title: A Prospective, Randomized, Controlled, Multicenter, Phase II / III, Clinical Study to Evaluate the Effectiveness and Safety of NTC chondrograft® versus the Standard Procedure Arthroscopic Microfrac...
    Medical condition: Symptomatic knee articular cartilage defects
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-001431-31 Sponsor Protocol Number: EMR700692-007 Start Date*: 2013-05-02
    Sponsor Name:Merck KGaA
    Full Title: A multicenter, randomized, double-blind, placebo-controlled, parallel-group, Phase II trial to investigate the efficacy and safety of 30 mcg and 100 mcg AS902330 given as one cycle of three intra-a...
    Medical condition: Knee Cartilage Injury
    Disease: Version SOC Term Classification Code Term Level
    15.1 10022117 - Injury, poisoning and procedural complications 10007710 Cartilage injury PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-001457-26 Sponsor Protocol Number: A6171016 Start Date*: 2008-04-24
    Sponsor Name:Pfizer Inc, 235 East 42nd Street, New York, NY 10017
    Full Title: A LONG-TERM, RANDOMIZED, DOUBLE-BLIND, PARALLEL-GROUP, PLACEBO-CONTROLLED, RADIOGRAPHIC STUDY TO INVESTIGATE THE SAFETY AND EFFICACY OF ORALLY ADMINISTERED SD-6010 IN SUBJECTS WITH SYMPTOMATIC OSTE...
    Medical condition: Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: HU (Completed) BE (Completed) DE (Completed) ES (Completed) CZ (Completed) SK (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2015-003587-36 Sponsor Protocol Number: 684/MODREC/15 Start Date*: 2016-04-13
    Sponsor Name:Directorate of Defence Rehabilitation
    Full Title: Chronic Tendinopathy: The Biomechanical Associations and EfFicacy of Injectable Therapy (BE FIT) Study
    Medical condition: Chronic degenerative Achilles and patella tendinopathy patients, with neovascularisation on USS, who have failed best practice rehabilitation including Eccentric Loading (EL), Heavy Slow Resistance...
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004859 10000433 Achilles tendinitis LLT
    18.1 100000004859 10034123 Patellar tendinitis LLT
    Population Age: Adults Gender: Male
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2015-005421-40 Sponsor Protocol Number: RCSI-1764 Start Date*: 2016-06-14
    Sponsor Name:Royal College of Surgeons in Ireland
    Full Title: The use of topical Glyceryl Trinitrate (GTN) and eccentric exercises in the treatment of mid portion Achilles Tendinopathy: a randomised placebo controlled trial
    Medical condition: Achilles tendinopathy
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004859 10050471 Achilles tendon pain LLT
    18.1 100000004859 10050129 Achilles tendon thickening LLT
    18.1 100000004863 10000435 Achilles tendon injury LLT
    18.1 100000004859 10000433 Achilles tendinitis LLT
    18.1 100000004859 10000441 Achilles tendonitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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