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Clinical trials for Pain threshold

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    124 result(s) found for: Pain threshold. Displaying page 1 of 7.
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    EudraCT Number: 2005-002159-41 Sponsor Protocol Number: Mo_top_Sb_100505 Start Date*: 2005-10-03
    Sponsor Name:Department of Anaesthesia & General Intensive Care Medicine
    Full Title: Investigation of the antihyperalgesic effect of topical buprenorphine in an UV-B induced inflammatory skin pain model in healthy volunteers
    Medical condition: Volunteer study with healthy volunteers using the UV-B-model as model of hyperalgesia.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2007-003277-19 Sponsor Protocol Number: nd Start Date*: 2007-09-03
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: modifications on the pain-threshold in labour and the effects of the epidural analgesia and S-Ketamina on the pai-threshold
    Medical condition: pain-threshold
    Disease: Version SOC Term Classification Code Term Level
    6.1 10029772 HLT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-000048-32 Sponsor Protocol Number: 15-062 Start Date*: 2018-03-01
    Sponsor Name:RWTH Aachen University/CTC-A
    Full Title: Evaluation of the Therapeutic Effects of Testosterone on Pain Perception in case of Chronic Pain Disorder
    Medical condition: Patient with persistent somatoform pain disorder (F45.40 or F45.41) should be included into the study.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-005627-32 Sponsor Protocol Number: IIVOP Start Date*: 2014-06-12
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge
    Full Title: A randomised, double blind, placebo controlled crossover study of the influence of the HCN channel blocker ivabradine in a healthy volunteer pain model - an enriched population study
    Medical condition: Neuropathic Pain
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004852 10054095 Neuropathic pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-000839-54 Sponsor Protocol Number: SMi-MW-12 Start Date*: 2012-06-07
    Sponsor Name:Rigshospitalet
    Full Title: The effect of late naloxon-infusion on secondary hyperalgesia after a first degree burn injury
    Medical condition: Induced pain in volunteers
    Disease: Version SOC Term Classification Code Term Level
    14.1 10018065 - General disorders and administration site conditions 10033371 Pain PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-020042-94 Sponsor Protocol Number: LS07-040 Start Date*: 2010-09-02
    Sponsor Name:Medizinische Universität Wien, Universitätsklinik für Anästhesie, Allgemeine Intensivmedizin
    Full Title: The Effect of High-dose Remifentanil on the Reversal of Neuropathic Pain in Postherpetic Patients
    Medical condition: Post herpetic hyperalgesia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2014-005651-89 Sponsor Protocol Number: SM2-JH-2014 Start Date*: 2015-04-23
    Sponsor Name:Køge Sygehus
    Full Title: Does perineural dexmedetomidine prolong the duration of an adductor canal block when controlling for a systemic effect? - a randomized, blinded, paired study in healthy volunteers
    Medical condition: Healthy volunteers (treatment intended for pain treatment in patients after knee surgery)
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2014-005640-18 Sponsor Protocol Number: SM1-JH-14 Start Date*: 2015-07-21
    Sponsor Name:Køge Sygehus
    Full Title: Does perineural clonidin prolong the duration of an adductor canal block when controlling for a systemic effect? - a randomized, blinded, paired study in healthy volunteers.
    Medical condition: Healthy volunteers (treatment intended for pain treatment in patients after knee surgery)
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2016-002643-41 Sponsor Protocol Number: SM1-KHTY-16 Start Date*: 2016-08-29
    Sponsor Name:Department of Anesthesiology, Næstved Hospital
    Full Title: Sensory distribution of lateral femoral cutaneous nerve block - a randomised, blinded, paired trial in heathy volunteers
    Medical condition: Healthy volunteers (treatment intended for pain treatment in patients after hip surgery)
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2007-003848-30 Sponsor Protocol Number: 07 I / FHp04 Start Date*: 2007-09-25
    Sponsor Name:IBSA
    Full Title: Effects of a plaster containing diclofenac epolamine (DHEP) and heparin on the pain threshold in asymptomatic subjects (no spon-taneous pain) with a latent algogenic condition (subcutaneous and/or ...
    Medical condition: Subjects with no spontaneous pain since one month before the enrolment, with hyperalgesia and trophic changes of deep somatic structures from latent algogenic conditions of the lower limbs.
    Disease: Version SOC Term Classification Code Term Level
    6.1 10028395 SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2019-003561-17 Sponsor Protocol Number: 750CNP01 Start Date*: 2020-01-23
    Sponsor Name:Toray Industries, Inc.
    Full Title: A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of TRK-750 in Colorectal Cancer Patients with Chemotherapy-induced Peripheral Neuropathy Following Oxaliplatin-con...
    Medical condition: Chemotherapy-induced peripheral neuropathy
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004852 10079545 Chemotherapy induced peripheral neuropathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) DE (Prematurely Ended) ES (Prematurely Ended) DK (Prematurely Ended) FR (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-000395-32 Sponsor Protocol Number: 2006001 Start Date*: 2006-03-29
    Sponsor Name:King's College London
    Full Title: The effect of COX-2 Inhibition on Reducing Central Sensitisation of Pain in Osteoarthritis
    Medical condition: Osteoarthritis of the knee
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-001822-24 Sponsor Protocol Number: SM1-PJ-13 Start Date*: 2013-05-28
    Sponsor Name:Professor Jørgen B. Dahl
    Full Title: The effect of different doses (mass) of local anesthetic on duration of adductor canal block in healthy volunteers.
    Medical condition: healthy volunteers ( intended for postoperative pain treatment in patients after knee surgery)
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-001752-31 Sponsor Protocol Number: SM1-PJ-14 Start Date*: 2014-06-18
    Sponsor Name:Professor Jørgen B. Dahl
    Full Title: The effect of different doses (mass) of local anesthetic on duration of adductor canal block in healthy volunteers - part 2
    Medical condition: healthy volunteers ( intended for postoperative pain treatment in patients after knee surgery)
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2009-015780-14 Sponsor Protocol Number: High-Dose-RemiSun Start Date*: 2009-12-28
    Sponsor Name:Abteilung für Anästhesie und Intensivmedizin, Medizinische Universität Wien
    Full Title: The effect of high dose remifentanil on the reversal of established sunburn-induced hyperalgesia in human volunteers
    Medical condition: Volunteer study with 24 healthy volunteers to perform pain research and to study the reversal of hyperalgesia by IMP
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2014-004879-23 Sponsor Protocol Number: SM2-PJ-14 Start Date*: 2015-01-09
    Sponsor Name:Bispebjerg Hospital
    Full Title: Does perineural dexamethason prolong duration of an adductor canal block when controlling for a systemic effect? A randomized, blinded, crossover study in healthy volunteers
    Medical condition: Healthy volunteers (intended for postoperative pain treatment in patients after knee surgery)
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004865 10036236 Postoperative pain relief LLT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2005-004082-42 Sponsor Protocol Number: OXY-2 Start Date*: 2005-12-05
    Sponsor Name:Søren Sindrup, Dept. of Neurology, University Hospital of Odense
    Full Title: The Pharmacogenetics of Oxycodone analgesia in human experimental pain models
    Medical condition: Healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2011-006206-27 Sponsor Protocol Number: Gra-geneticver1 Start Date*: 2012-02-21
    Sponsor Name:Karolinska Institutet
    Full Title: Does 5-HT polymorphism contribute to pain regulation and efficacy of granisetron?
    Medical condition: Experimentally induced muscle pain in healthy volunteers, both sexes and over 18 years of age.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2005-002959-41 Sponsor Protocol Number: FLUPI-5014 Start Date*: 2005-10-10
    Sponsor Name:AWD.pharma GmbH & Co. KG; Medical Development
    Full Title: A multicentre, double-blind, randomised, placebo-controlled clinical trial to investigate pain relieving effects of the modified release (MR) formulation of flupirtine in patients suffering from mo...
    Medical condition: chronic low back pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-000103-20 Sponsor Protocol Number: 202000638 Start Date*: 2021-07-15
    Sponsor Name:University Medical Center Groningen
    Full Title: An explorative randomized, placebo-controlled and double-blind intervention crossover study: Transvamix (100mg/mL THC / 50mg/mL CBD) to treat chronic pain in Epidermolysis Bullosa
    Medical condition: Genetic Epidermolysis Bullosa
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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