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Clinical trials for Pediatrics

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    91 result(s) found for: Pediatrics. Displaying page 1 of 5.
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    EudraCT Number: 2015-002675-19 Sponsor Protocol Number: TMZ-CSF-001 Start Date*: 2015-10-06
    Sponsor Name:Medical University of Vienna, Department of Pediatrics
    Full Title: Pharmacokinetics of temozolomide in cerebrospinal fluid in children with malignant brain tumors
    Medical condition: Recurrent malignant childhood central nervous system tumors
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2006-004749-40 Sponsor Protocol Number: PEDMet 2006-1 Start Date*: 2006-11-20
    Sponsor Name:Pediatrics
    Full Title: Glucose metabolism in patients with neurological/neuromuscular diseases.
    Medical condition: Patients with neurological/neuromuscular diseases
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-002658-19 Sponsor Protocol Number: 20016-01 Start Date*: 2018-06-25
    Sponsor Name:Department für Kinder- und Jugendheilkunde, Pädiatrie I
    Full Title: Influence of pulsatile dexamethasone therapy in childhood epilepsia on the immune Systeme.
    Medical condition: Analization of specific immune cells and immune modulation factors in children under pulsatile dexamethasone-therapy.
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2018-000565-36 Sponsor Protocol Number: 38/2018 Start Date*: 2018-06-05
    Sponsor Name:University of Oulu
    Full Title: Paracetamol and ibuprofen/indomethacin in closing persistent ductus arteriosus
    Medical condition: Patent ductus arteriosus of a premature infant
    Disease:
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-002844-18 Sponsor Protocol Number: 04071962 Start Date*: 2017-01-16
    Sponsor Name:Medical University of Vienna, Dpt. of Pediatrics
    Full Title: Preventive sublingual immunotherapy for house dust mite sensitized preschool children
    Medical condition: Patients; children at age 4 years with house dust mite IgE sensitization without allergic disease
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-000174-11 Sponsor Protocol Number: CN138603 Start Date*: 2017-04-07
    Sponsor Name:Otsuka Pharmaceutical Development & Commercialization, Inc
    Full Title: Safety and Efficacy of Aripiprazole in the Long-Term Maintenance Treatment of Pediatric Subjects with Irritability Associated with Autistic Disorder
    Medical condition: Irritability in Autism Disorder
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2021-001069-20 Sponsor Protocol Number: HIDROGUM21 Start Date*: 2022-01-12
    Sponsor Name:Vall d'Hebron Hospital Universitari
    Full Title: Tolerability and acceptance of two oral hydrocortisone compounding formulation for pediatrics
    Medical condition: Adrenal hyperplasia or isolated primary adrenal insufficiency or panhypopituitarism (secondary or tertiary adrenal insufficiency)
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-000310-19 Sponsor Protocol Number: 2011-000310-19 Start Date*: 2011-08-09
    Sponsor Name:Lund University
    Full Title: Fentanyl treatment in newborn infants: A Pharmacokinetic, Pharmacodynamic, and Pharmacogenetic Study (PK/PD model)
    Medical condition: Neonatal Pain
    Disease:
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: SE (Completed) FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-006602-24 Sponsor Protocol Number: PNC-2007 Start Date*: 2008-03-31
    Sponsor Name:Department of Pediatrics, Medical and Health Science Center, University of Debrecen
    Full Title: Relative adrenal insufficiency in children with pneumonia and sepsis. Efficacy of i.v. prednisolon for prevention of complication of pneumonia. A prospective, parallel-group, randomised trial.
    Medical condition: Severe complications of bacterial pneumonia i.e. abscess formation, empyema and sepsis in children. Supposed concomittant andrenal insuficiency is also planned to investigate.
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2020-005996-11 Sponsor Protocol Number: MK-1654-007 Start Date*: 2021-08-26
    Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
    Full Title: A Phase 3, Multicenter, Randomized, Partially Blinded, Palivizumab-Controlled Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of MK-1654 in Infants and Children at Increased Risk for S...
    Medical condition: Prevention of Respiratory syncytial virus (RSV) infection in infants and children at increased risk for severe RSV disease
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10066742 Respiratory syncytial virus infection prophylaxis LLT
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: ES (Trial now transitioned) DE (Trial now transitioned) FI (Trial now transitioned) Outside EU/EEA HU (Trial now transitioned) FR (Trial now transitioned) NO (Trial now transitioned) GR (Trial now transitioned) CZ (Trial now transitioned) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2013-000122-60 Sponsor Protocol Number: 1.0 Start Date*: 2013-05-17
    Sponsor Name:Karolinska University Hospital, Division of Pediatrics/Astrid Lindgren Children´s Hospital
    Full Title: The effect of dexmedetomidine as an adjuvant to local anaesthetics for ilioinguinal blocks in paediatric patients
    Medical condition: Pediatric patients receive ilioinguinal-iliohypogastric nerve blockade with 0.2ml/kg ropivacaine 0.197% and 0.3µg/kg dexmedetomidine or 0.2ml/kg ropivacaine 0.197% and saline as a placebo. Aim of t...
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-003251-11 Sponsor Protocol Number: DIABGAD-1 Start Date*: 2012-11-21
    Sponsor Name:Linköping university
    Full Title: Pilot Trial to preserve residual insulin secretion in children and adolescents with recent onset Type 1 diabetes by using GAD-antigen (Diamyd) therapy in combination with Vitamin D and Ibuprofen .
    Medical condition: Type 1 diabetes in children and adolescents
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2006-001563-37 Sponsor Protocol Number: Prot-Cur 3. Start Date*: 2006-10-10
    Sponsor Name:Department of Pediatrics Holbaek Hospital
    Full Title: Tidlig selektiv behandling med Curosurf. Behandling af RDS efter bestemmelse af lamellar body counts på ventrikelaspirat sammenholdt med behandling ved a/APO2 <0,36 En randomiseret kontrolleret mul...
    Medical condition: Respiratory Distress Syndrome (RDS) in infants 24-29 weeks`gestation
    Disease:
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: DK (Completed) SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-002876-41 Sponsor Protocol Number: 38RC18.123 Start Date*: 2019-03-27
    Sponsor Name:CHU Grenoble-Alpes
    Full Title: Assesment of Propofol sedation during intra tracheal surfactant administration by the LISA method (Less Invasive Surfactant Administration)
    Medical condition: Respiratory Distress Syndrome of preterm babies born < 32 weeks of gestational age
    Disease:
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2009-015163-14 Sponsor Protocol Number: 73191198 Start Date*: 2010-01-08
    Sponsor Name:Department of Pediatrics Aarhus University Hospital Skejby
    Full Title: Reduction of hypertrophic scars and keloid by use of corticosteroid cream after removal of a tunneled central venous catheter in childhood cancer survivors
    Medical condition: Development of hypertrophic and keloid scars after removal of tunneled central venous catheters in childhood cancer survivors
    Disease: Version SOC Term Classification Code Term Level
    12.0 10020879 Hypertrophic scar LLT
    12.0 10023330 Keloid scar LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-001721-26 Sponsor Protocol Number: B9R-EW-GDFC(a) Start Date*: 2006-09-25
    Sponsor Name:UAB “Eli Lilly Lietuva”
    Full Title: The Genetics and Neuroendocrinology of Short Stature International Study (GeNeSIS)
    Medical condition: Short Stature
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: LT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-001946-26 Sponsor Protocol Number: AMITNED Start Date*: 2016-01-19
    Sponsor Name:Aarhus University Hospital
    Full Title: Amilorid treatment of nephrotic edema
    Medical condition: Childhood idiopathic nephrotic syndrome (NS)
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-004427-11 Sponsor Protocol Number: 060317 Start Date*: 2006-10-27
    Sponsor Name:Univ of Lund, Dept of Pediatrics
    Full Title: Effects of Omega-3-Fatty Acids on Arterial Endothelial Function and Intima Media Thickness in Children with Insulin-Dependent Diabetes Mellitus
    Medical condition: Diabetes mellitus type 1 in children
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-010965-22 Sponsor Protocol Number: NF1-SIMCODA Start Date*: 2009-09-29
    Sponsor Name:Erasmus MC - Department of Pediatrics
    Full Title: The effect of long-term simvastatin treatment on cognitive function and daily life in children with Neurofibromatosis 1: a one year randomized controlled trial
    Medical condition: Neurofibromatosis 1
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2018-000566-11 Sponsor Protocol Number: 39-2018 Start Date*: 2018-06-05
    Sponsor Name:University of Oulu
    Full Title: Extremely low gestational age infants' PARAcetamol Study
    Medical condition: Open ductus arteriosus of a premature infant
    Disease:
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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