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Clinical trials for Phenytoin

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    51 result(s) found for: Phenytoin. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2004-005046-12 Sponsor Protocol Number: Final protocol Start Date*: 2005-09-22
    Sponsor Name:Ulster Community & Hospitals Trust
    Full Title: A double blind prospective randomised controlled trial to evaluate the effect of topical phenytoin on the healing of venous leg ulcers
    Medical condition: Venous Leg Ulceration
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2011-003475-11 Sponsor Protocol Number: UCL/11/0083 Start Date*: 2011-11-15
    Sponsor Name:University College London (UCL)
    Full Title: A phase II double-blind, randomised, placebo-controlled trial of neuroprotection with phenytoin in acute optic neuritis
    Medical condition: Acute demyelinating optic neuritis
    Disease: Version SOC Term Classification Code Term Level
    16.0 10029205 - Nervous system disorders 10030942 Optic neuritis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-001222-42 Sponsor Protocol Number: CAPSS-272 Start Date*: 2015-04-24
    Sponsor Name:Johnson & Johnson Pharmaceutical Research and Development, L.L.C.
    Full Title: A double-blind trial comparing the efficacy, tolerability and safety of monotherapy topiramate versus phenytoin in subjects with seizures indicative of new onset epilepsy
    Medical condition: New onset epilepsy
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2004-004787-74 Sponsor Protocol Number: Final protocol Start Date*: 2005-04-19
    Sponsor Name:Royal Group of Hospitals Trust
    Full Title: A double blind, prospective, randomised, controlled clinical trial to evaluate the effect of topical phenytoin, on healing, in diabetic foot ulcers.
    Medical condition: Diabetes Mellitus and associated diabetic foot ulceration
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2020-001340-25 Sponsor Protocol Number: UMC-NMZ-EPHENE2020 Start Date*: 2020-07-17
    Sponsor Name:University Medical Center Utrecht
    Full Title: Enrichment randomized double-blind, placebo-controlled cross-over trial with PHEnytoin cream in patients with painful chronic idiopathic axonal polyNEuropathy
    Medical condition: Painful chronic idiopathic axonal polyneuropathy
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004852 10040040 Sensory polyneuropathy axonal LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-001611-20 Sponsor Protocol Number: 357-0-0 Start Date*: 2018-07-24
    Sponsor Name:University of Tübingen
    Full Title: Pathophysiology-based therapy of epileptic encephalopathies
    Medical condition: patients with epileptic encephalopathies
    Disease:
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-001562-13 Sponsor Protocol Number: OX25574 Start Date*: 2006-02-03
    Sponsor Name:AZIENDA OSPEDALIERO UNIVERSITARIA OSPEDALI RIUNITI UMBERTO I - G.M.LANCISI - G.SALESI
    Full Title: OXCARBAZEPINE VS PHENYTOIN IN THE TREATMENT OF SEIZURES IN PATIENTS WITH BRAIN TUMORS UNDERGOING NEUROSURGICAL PROCEDURES
    Medical condition: SEIIZURES IN PATIENTS WITH BRAIN TUMORS
    Disease: Version SOC Term Classification Code Term Level
    9.1 10053551 Intractable epilepsy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-000487-92 Sponsor Protocol Number: SPJK/06/01 Start Date*: 2006-11-21
    Sponsor Name:Royal College of Surgeon's Ireland
    Full Title: A Phase II, Randomised, Double Blind, Placebo Controlled Study examining the suitability of Phenytoin Sodium Topical Gel in the treatement of Venous Ulcers
    Medical condition: Venous ulcers in the lower leg.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-002188-13 Sponsor Protocol Number: UoL001087 Start Date*: 2015-03-03
    Sponsor Name:University of Liverpool [...]
    1. University of Liverpool
    2. Alder Hey Children's NHS Foundation Trust
    Full Title: Emergency Treatment with Levetiracetam or Phenytoin in Status Epilepticus in Children (EcLiPSE) – an open label randomised controlled trial
    Medical condition: Convulsive Status Epilepticus
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004852 10057955 Convulsive status epilepticus LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2020-000282-16 Sponsor Protocol Number: MAST Start Date*: Information not available in EudraCT
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and The University of Cambridge
    Full Title: Pharmacological management of seizures post traumatic brain injury (MAST)
    Medical condition: Post traumatic seizures following traumatic brain injury
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10039911 Seizures (incl subtypes) HLGT
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2013-002195-40 Sponsor Protocol Number: 13/0656 Start Date*: 2014-09-02
    Sponsor Name:University College London
    Full Title: A randomised controlled trial of the ketogenic diet in the treatment of epilepsy in children under the age of two years
    Medical condition: Epilepsy
    Disease: Version SOC Term Classification Code Term Level
    17.0 10029205 - Nervous system disorders 10015037 Epilepsy PT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2004-003945-41 Sponsor Protocol Number: N/A Start Date*: 2005-02-15
    Sponsor Name:liverpool university
    Full Title: Pharmacogenetics of GABAergic mechanisms of benefit and harm in epilepsy: : A prospective cohort study to determine the enviromental and genetic factors associated with response to clobazam.
    Medical condition: Epilepsy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-019361-28 Sponsor Protocol Number: N01358 Start Date*: 2011-03-15
    Sponsor Name:UCB BioSciences Inc. A Member of the UCB Group of Companies
    Full Title: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER, PARALLEL-GROUP STUDY TO EVALUATE THE EFFICACY AND SAFETY OF BRIVARACETAM IN SUBJECTS (≥16 TO 80 YEARS OLD) WITH PARTIAL ONSET SEIZURES
    Medical condition: Focal Epilepsy
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10061334 Partial seizures PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) DE (Completed) CZ (Completed) ES (Completed) IT (Completed) GB (Completed) SE (Completed) FR (Ongoing) FI (Completed) AT (Completed) NL (Completed) EE (Completed) LT (Completed) LV (Completed) HU (Completed) BG (Completed) RO (Completed)
    Trial results: View results
    EudraCT Number: 2014-002594-11 Sponsor Protocol Number: GWEP1330 Start Date*: 2015-01-24
    Sponsor Name:GW Research Ltd.
    Full Title: A double blind, randomized, placebo-controlled, two-part study to investigate the pharmacokinetics, followed by efficacy and safety of GWP42006 as add-on therapy in patients with inadequately contr...
    Medical condition: Epilepsy
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004852 10016843 Focal seizures LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) CZ (Completed) ES (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2007-003834-40 Sponsor Protocol Number: 07NR07 Start Date*: 2008-10-31
    Sponsor Name:UCL-INSTITUTE OF CHILD HEALTH
    Full Title: THE IMPACT OF REDUCING OVERTREATMENT ON QUALITY OF LIFE IN CHILDREN WITH REFRACTORY EPILEPSY
    Medical condition: We are studying a population of children with refractory epilepsy.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10053551 Intractable epilepsy LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-003303-31 Sponsor Protocol Number: BAY59-7939/13238 Start Date*: 2009-01-13
    Sponsor Name:Bayer HealthCare AG
    Full Title: The Einstein CYP cohort study. Oral direct factor Xa inhibitor rivaroxaban in patients with acute symptomatic deep-vein thrombosis or pulmonary embolism using a strong CYP 3A4 inducer.
    Medical condition: Patients with acute, proximal DVT or acute PE who concomitantly use a strong CYP 3A4 inducer for the entire 3-month study duration.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) DE (Completed) HU (Prematurely Ended) AT (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-003325-41 Sponsor Protocol Number: 668353 Start Date*: 2017-06-09
    Sponsor Name:Leiden University Medical Center
    Full Title: PREemptive Pharmacogenomic testing for Preventing Adverse drug REactions
    Medical condition: Adverse drug reactions
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-004378-92 Sponsor Protocol Number: EdomTHC Start Date*: 2019-05-27
    Sponsor Name:Fundació Clínic per la Recerca Biomèdica
    Full Title: Effect of cannabinoids (THC / CBD) on hyperalgesia in patients with deep endometriosis
    Medical condition: Deep endometriosis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038604 - Reproductive system and breast disorders 10014778 Endometriosis PT
    Population Age: Adults Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-002109-24 Sponsor Protocol Number: E2007-J000-335 Start Date*: 2020-06-17
    Sponsor Name:Eisai Co., Ltd.
    Full Title: A Double-blind, Placebo-controlled, Parallel-group Study With an Openlabel Extension Phase to Evaluate the Efficacy and Safety of Perampanel (E2007) Administered as an Adjunctive Therapy in Subject...
    Medical condition: Refractory Partial-onset Seizures
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029205 - Nervous system disorders 10015037 Epilepsy PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2011-000374-60 Sponsor Protocol Number: N01266 Start Date*: 2011-07-05
    Sponsor Name:UCB Pharma SA
    Full Title: OPEN-LABEL, SINGLE-ARM, MULTICENTER, LONG-TERM STUDY TO EVALUATE SAFETY AND EFFICACY OF BRIVARACETAM USED AS ADJUNCTIVE TREATMENT IN PEDIATRIC SUBJECTS WITH EPILEPSY
    Medical condition: Localization-related, generalized or undetermined whether focal or generalized epileptic syndrome, according to ILAE classification
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10015037 Epilepsy PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed) CZ (Completed) ES (Completed) PL (Completed) Outside EU/EEA IE (Completed) GB (GB - no longer in EU/EEA) DE (Completed) HU (Completed) NL (Completed) FR (Completed) IT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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