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Clinical trials for Premedication

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44346   clinical trials with a EudraCT protocol, of which   7374   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    66 result(s) found for: Premedication. Displaying page 1 of 4.
    1  2  3  4  Next»
    EudraCT Number: 2019-001853-25 Sponsor Protocol Number: 1.2-24.05.2019 Start Date*: 2019-07-23
    Sponsor Name:Medical University of Vienna
    Full Title: THE USE OF ADV6209 FOR PREMEDICATION IN PAEDIATRIC ANAESTHESIA: A CONTROLLED, RANDOMIZED, DOUBLE BLINDED STUDY
    Medical condition: To evaluate the effect of ADV6209, a new oral Midazolam formulation, on preoperative anxiety and sedation levels in paediatric anaesthesia
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2018-002383-38 Sponsor Protocol Number: OY062018 Start Date*: 2018-10-17
    Sponsor Name:University of Oulu
    Full Title: Premedication for less invasive surfactant administration
    Medical condition: The aim of this randomized, controlled trial is to evaluate the feasibility, efficacy and safety of less invasive surfactant administration (LISA) protocol with the premedication of either ketamine...
    Disease:
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: FI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2022-003117-11 Sponsor Protocol Number: BCD101 Start Date*: 2023-10-24
    Sponsor Name:Dentlabe s.r.o.
    Full Title: Study assessing if oxytocin can be used as premedication for anxious patients in dentistry.
    Medical condition: Premedication in dentistry
    Disease: Version SOC Term Classification Code Term Level
    21.0 10042613 - Surgical and medical procedures 10036500 Premedication PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-012808-11 Sponsor Protocol Number: MID001 Start Date*: Information not available in EudraCT
    Sponsor Name:Therakind Limited
    Full Title: An open label, single dose, pharmacokinetic study of oromucosal midazolam administered to children from 3 months to less than 18 years undergoing routine elective surgery
    Medical condition: In the context of the trial, the IMP is to be used as anaesthetic premedication in children undergoing elective routine surgery. (The medical condition for marketing is acute seizures in children ...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10058073 Anaesthetic premedication LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-004456-42 Sponsor Protocol Number: P2021/Anesth/MIDEXMRI Start Date*: 2022-06-21
    Sponsor Name:Hôpital Universitaire Des Enfants Reine Fabiola
    Full Title: Prospective, randomized, double-blind, double-dummy, active-controlled, phase 3 clinical trial comparing the safety and efficacy of intranasal dexmedetomidine to oral midazolam as premedication for...
    Medical condition: pre-school pediatric population undergoing magnetic resonance imaging
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-005215-42 Sponsor Protocol Number: KloMid02 Start Date*: 2013-04-12
    Sponsor Name:Department of Anesthesiology and Intensive Care Medicine
    Full Title: Children's mood/anxiety, pain, nausea and behavioral changes after premedication with Clonidine versus Midazolam in ENT day surgery.
    Medical condition: Preanesthetic Medication at ear-nose-throat surgery
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-004895-13 Sponsor Protocol Number: 1.0 Start Date*: 2013-01-30
    Sponsor Name:Medizinische Universität Wien, Universitätsklinik für Anästhesie, Allgemeine Intensivmedizin und Schmerztherapie
    Full Title: Medical premedication in contrast to psychological preparation in children
    Medical condition: Children who have to undergo a pediatric surgery procedure get preoperative midazolam 1mg/kg but maximum 15mg. It is a common problem, that in children with a weight more than 15 kilos premedicatio...
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-024018-71 Sponsor Protocol Number: 2010-024018-71 Start Date*: 2011-03-31
    Sponsor Name:AZIENDA UNIVERSITARIA POLICLINICO UMBERTO I DI ROMA
    Full Title: PREMEDICATION IN CHILDREN: CLONIDINE VERSUS MELATONIN
    Medical condition: HEALTHY CHILDREN UNDERGOING ELECTIVE MINOR SURGERY
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-000714-74 Sponsor Protocol Number: 1.0 Start Date*: 2008-07-15
    Sponsor Name:Institution of Paediatric Anaesthesia and intensiv care, Astrid Lindgren Childrens Hospital, Karolin
    Full Title: Premedication in paediatric patients: Dose finding study of clonidine administrated as nasal aerosol.
    Medical condition: Premedication prior to anaesthesia
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-018992-16 Sponsor Protocol Number: PI10 - Pr. Dupont Start Date*: 2010-12-30
    Sponsor Name:Centre hospitalier universitaire d'Amiens
    Full Title: Evaluation pharmacocinétique de MDZ028 après administration unique d'une forme orale nouvelle, lors de la prémédication anesthésique chez l'enfant.
    Medical condition: prémédication anesthésique
    Disease: Version SOC Term Classification Code Term Level
    12.1 10058073 Anaesthetic premedication LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-003535-11 Sponsor Protocol Number: 2017-003535-11 Start Date*: 2018-09-21
    Sponsor Name:Erasmus MC [...]
    1. Erasmus MC
    2. Maasstad Hospital
    Full Title: The added value of the H2-antagonist ranitidine in premedication regimens during paclitaxel treatment
    Medical condition: Paclitaxel-induced hypersensitivity reactions
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-003638-10 Sponsor Protocol Number: 2016_37 Start Date*: Information not available in EudraCT
    Sponsor Name:CHRU LILLE
    Full Title: INTRANASAL CLONIDINE PREDICTION IN PEDIATRIC SURGERY: RANDOMIZED STUDY AGAINST PLACEBO
    Medical condition: intra-nasal premedication instead of oral, intravenous or no premedication.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10042609 Surgery PT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-002906-38 Sponsor Protocol Number: 58525 Start Date*: 2016-10-12
    Sponsor Name:MC Slotervaart
    Full Title: Reducing pain and discomfort during and after bone marrow aspiration
    Medical condition: Pain and fear reduction for bone marrow examination
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-014885-25 Sponsor Protocol Number: CHIC001 Start Date*: Information not available in EudraCT
    Sponsor Name:Centre Hospitalier Intercommunal de Créteil
    Full Title: PRETTINEO PREmedication Trial for Tracheal Intubation of the NEOnate
    Medical condition: Comparison of two premedication regimens for semi-elective or elective intubation of newborns (term and preterm) hospitalized in the NICU
    Disease: Version SOC Term Classification Code Term Level
    13.1 10042613 - Surgical and medical procedures 10067450 Endotracheal intubation PT
    13.1 10042613 - Surgical and medical procedures 10036500 Premedication PT
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: View results
    EudraCT Number: 2005-001791-13 Sponsor Protocol Number: OXY4009 Start Date*: 2005-08-31
    Sponsor Name:Mundipharma GmbH
    Full Title: An open-label, randomized, parallel-group, monocenter study to evaluate safety and efficacy of Oxycodone Hydrochloride administered orally (CR) and intravenously in patients with total hip endopros...
    Medical condition: Male and female patients who are designated for a total hip endoprosthesis
    Disease: Version SOC Term Classification Code Term Level
    7.1 10044088 low
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-003795-39 Sponsor Protocol Number: TKADEX Start Date*: 2020-12-15
    Sponsor Name:Turku University Hospital
    Full Title: Premedication with intranasal dexmedetomidine in sedation of patients undergoing total knee arthroplasty (TKADEX) - a prospective, double blinded randomized controlled trial
    Medical condition: Knee arthrosis
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004859 10031165 Osteoarthritis knee LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-014256-30 Sponsor Protocol Number: HU08/NEONAT/REMIFENTANIL Start Date*: 2009-09-11
    Sponsor Name:Hôpital Universitaire Des Enfants Reine Fabiola
    Full Title: Une analgésie de choix pour l'intubation des nouveau-nés : Etude multicentrique randomisée comparant le rémifentanil à l'association morphine-midazolam
    Medical condition: Preterm newborn & newborm requiring an elective endotacheal intubation
    Disease: Version SOC Term Classification Code Term Level
    12.0 10067450 Endotracheal intubation LLT
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-020332-19 Sponsor Protocol Number: Prot-22121988-2010 Start Date*: 2010-08-23
    Sponsor Name:ERASMUS MC, Dept Anesthesiology
    Full Title: Putting Resistance under the Microscope. (Weerstand onder de Loep)
    Medical condition: Patients resistance concerning diagnostic or therapeutic procedure are well known. In this trial patients-resistance during the perioperative period will be investigated in day-case-surgery. Feat...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10002865 Anxiety reaction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-001583-52 Sponsor Protocol Number: Intu Start Date*: 2004-09-22
    Sponsor Name:Lund University Hospital
    Full Title: Balanced anestesia for intubation of newborn premature infants – a randomized intervention study Balanserad anestesi för intubation av nyfödda prematura barn – en randomiserad interventionsstudie
    Medical condition: Respiratory insufficiency in prematrue infants requiring ventilatory assistance and therefore intubation. Premedication before intubation.
    Disease:
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2007-000043-10 Sponsor Protocol Number: 200701 Start Date*: 2007-01-30
    Sponsor Name:Fakultní nemocnice Královské Vinohrady
    Full Title: Combination of alpha2-adrenoreceptor agonists, opioids and ketamine for improving of perioperative course
    Medical condition: Praeanaesthetic preparation (premedication) for patients scheduled for laparoscopic cholecystectomy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008611 Cholecystectomy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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