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Clinical trials for Prophylactic surgery

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    158 result(s) found for: Prophylactic surgery. Displaying page 1 of 8.
    1  2  3  4  5  6  7  8  Next»
    EudraCT Number: 2009-011342-26 Sponsor Protocol Number: 06/09 Start Date*: 2009-11-12
    Sponsor Name:Great Western Hospital, Swindon
    Full Title: The use of prophylactic antibiotics for percutaneous K-wires in orthopaedic surgery
    Medical condition: INfection following k-wire insertion
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-001478-27 Sponsor Protocol Number: IRFMN-GCC-7813 Start Date*: 2019-09-11
    Sponsor Name:Associazione Chirurghi Ospedalieri Italiani
    Full Title: Prophylactic surgery plus hyperthermic intraperitoneal chemotherapy (HIPEC CO2) versus standard surgery in gastric carcinoma at high risk of peritoneal carcinomatosis. Short and long-term outcomes....
    Medical condition: Patients with gastric carcinoma at high risk of developing peritoneal carcinomatosis, suitable to radical surgery.
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004864 10007350 Carcinoma gastric LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-004232-37 Sponsor Protocol Number: Metylpred-01 Start Date*: 2012-11-29
    Sponsor Name:Sahlgrenska Universtitetssjukhuset/SUS
    Full Title: Prophylactic treatment with methylprednisolone may reduce the cerebral inflammatory response and reduce the severity of cognitive dysfunction after cardiac surgery
    Medical condition:
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-002756-21 Sponsor Protocol Number: 1663/2020 Start Date*: 2021-02-23
    Sponsor Name:Department of Cardiothoracic Anesthesia and Intensive Care Medicine, Medical University of Vienna
    Full Title: Plasma Pharmacokinetics of Prophylactic Cefazolin Administered for Cardiac Surgery: Comparison of Cardiopulmonary Bypass Priming with Additive Human Albumin 20% vs.Pure Crystalloid Priming: A singl...
    Medical condition: This is a pharmacokinetic trial for patients undergoing cardiac surgery. It will be investigated whether cardiopulmonary bypass priming substituted with human albumin 20% has an effect on the pharm...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-004070-29 Sponsor Protocol Number: E2011OBPROCHIR Start Date*: 2011-10-04
    Sponsor Name:Hopital Erasme
    Full Title: What are the optimal doses of cephalosporins of first and second generation to manage obese patients?
    Medical condition: Antibiotic prophylaxis in digestive surgery or any other surgery with antibiotic prophylaxis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10036898 Prophylaxis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2021-005493-25 Sponsor Protocol Number: EFISS Start Date*: Information not available in EudraCT
    Sponsor Name:Fakultní nemocnice Brno
    Full Title: Effect of Prophylactic Fibrinogen Concentrate In Scoliosis Surgery: A randomized pilot study (EFISS trial)
    Medical condition: Scoliosis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10039727 Scoliosis surgery PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-004297-26 Sponsor Protocol Number: C19-29 Start Date*: 2020-04-17
    Sponsor Name:Institut National de la Santé et de la Recherche Médicale (INSERM)
    Full Title: Prophylactic treatment of the ductus arteriosus in preterm infants by acetaminophen
    Medical condition: Patent ductus arteriosus
    Disease:
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: FR (Completed) EE (Completed) IE (Completed) FI (Completed) BE (Completed) PT (Completed) SE (Completed) HU (Completed) DK (Completed) GB (Not Authorised) NO (Completed) AT (Completed) GR (Completed) PL (Ongoing) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-006228-36 Sponsor Protocol Number: LT1225-PII-03/06 Start Date*: 2008-01-24
    Sponsor Name:Laboratoires Théa
    Full Title: Evaluación de la Eficacia y Seguridad de Azyter® (T1225) en la Profilaxis Antibiótica Perioperatoria (descontaminación de la superficie ocular) para la Cirugía de Catarata
    Medical condition: Profilaxis Antibiótica Perioperatoria (descontaminación de la superficie ocular)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064736 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing) FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-002746-35 Sponsor Protocol Number: D4003C00030 Start Date*: 2005-07-13
    Sponsor Name:AstraZeneca AB
    Full Title: The "EXTEND" study: A randomized, double-blind, parallel-group, phase IIIb, multi-centre study evaluating extended prophylactic treatment with melagatran/ximelagatran versus enoxaparin for the prev...
    Medical condition: Prophylactic treatment for the prevention of venous thromboembolic events in patients undergoing elective hip replacement or hip fracture surgery.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) SE (Completed) HU (Completed) AT (Completed) DK (Completed) DE (Completed) PT (Prematurely Ended) ES (Completed)
    Trial results: View results
    EudraCT Number: 2018-000109-22 Sponsor Protocol Number: MONATPRO Start Date*: 2018-05-31
    Sponsor Name:Fakultní nemocnice Hradec Králové
    Full Title: Monitoring of efficacy of antibiotic prophylaxis in thoracic surgery
    Medical condition: Antibiotic prophylaxis in thoracic surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10036894 Prophylactic antibiotic therapy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002803-17 Sponsor Protocol Number: 2340 Start Date*: 2008-09-04
    Sponsor Name:Med. Univ. Wien, Klinik Innere Medizin I, Intensivstation
    Full Title: PROPHYLACTIC, DOUBLE BLIND, PLACEBO CONTROLLED RANDOMIZED USE OF HOMEOPATHY FOR PREVENTION OF ATRIAL FIBRILLATION IN PATIENTS WITH AORTOCORONARY BYPASS OR HEART VALVE SURGERY WITH HEART-LUNG MACHINE
    Medical condition: Patients suffering from atrial fibrillation following heart surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-005477-37 Sponsor Protocol Number: 261303 Start Date*: 2016-01-26
    Sponsor Name:Baxalta Innovations GmbH
    Full Title: Phase 3, prospective, randomized, multi-center clinical study comparing the safety and efficacy of BAX 855 following PK-guided prophylaxis targeting two different FVIII trough levels in subjects wi...
    Medical condition: Severe hemophilia A (FVIII <1%)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000011915 10060612 Hemophilia A LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) AT (Completed) SE (Completed) CZ (Prematurely Ended) ES (Completed) HU (Completed) BG (Completed) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2020-003078-36 Sponsor Protocol Number: 727258 Start Date*: 2020-09-14
    Sponsor Name:Aarhus University Hospital
    Full Title: The RAS-study A reverse and anatomical prosthesis shoulder study Can we improve the prophylactic profile of antibiotic treatment in shoulder prosthesis surgery? - A clinical microdialysis study as...
    Medical condition: Orthopedic infections
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004862 10021799 Infection and inflammatory reaction due to other internal orthopedic device, implant, and graft LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2023-000502-26 Sponsor Protocol Number: TAK-660-3001 Start Date*: 2025-02-13
    Sponsor Name:Baxalta US Inc.
    Full Title: A Phase 3, Prospective, Multicenter, Open-label Study of Efficacy, Safety, and Pharmacokinetics of PEGylated Recombinant Factor VIII (ADYNOVATE) Administered for Prophylaxis and Treatment of Bleedi...
    Medical condition: Severe Hemophilia A (FVIII <1%)
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2004-002180-24 Sponsor Protocol Number: 2004An0007 Start Date*: 2005-04-12
    Sponsor Name:Swindon & Marlborough NHS Trust
    Full Title: Prospective randomised double blind comparative study of cinnarizine versus placebo as prophylactic anti-travel sickness therapy in patients undergoing dy-case gynaecological surgery.
    Medical condition: Post operative nausea and vomiting and motion sickness
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-001134-33 Sponsor Protocol Number: 012329 Start Date*: 2019-06-18
    Sponsor Name:Aarhus University Hospital
    Full Title: Does repeated administration of cefuroxime after orthopedic surgery provide a better prophylactic profile regarding postoperativ infection than a single administration of preoperative antimicrobia...
    Medical condition: Orthopedic infections.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10043658 Thumb osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2012-002409-23 Sponsor Protocol Number: 2012/421 Start Date*: 2012-09-21
    Sponsor Name:Aarhus University Hospital
    Full Title: Coagulation Profile in Patients Undergoing Video Assisted Thoracoscopic Surgery (VATS) for lung cancer - a randomized, controlled trial
    Medical condition: Coagulation profile in patients undergoing lung surgery due to cancer in the lung.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10049909 Venous thromboembolism prophylaxis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004961-26 Sponsor Protocol Number: 12-009 Start Date*: 2015-12-15
    Sponsor Name:McMaster University
    Full Title: Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY): A Multi-Center Randomized Controlled Study Comparing Alternative Antibiotic Regimens in Patients Undergoing Tumor Resections with Endopro...
    Medical condition: ? Patients with a primary bone malignancy or soft-tissue sarcoma that has invaded a lower extremity bone that are undergoing surgical treatment to resect the tumor and functionally reconstruct the ...
    Disease: Version SOC Term Classification Code Term Level
    18.1 10042613 - Surgical and medical procedures 10064736 Antibiotic prophylaxis PT
    18.1 100000004862 10056641 Post procedural site wound infection LLT
    18.1 10042613 - Surgical and medical procedures 10068943 Limb reconstructive surgery PT
    18.1 10042613 - Surgical and medical procedures 10036894 Prophylactic antibiotic therapy LLT
    18.1 10042613 - Surgical and medical procedures 10005978 Bone lesion excision PT
    18.1 10042613 - Surgical and medical procedures 10073235 Bone prosthesis insertion PT
    18.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006007 Bone sarcoma PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing) AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002090-12 Sponsor Protocol Number: Ilocard Start Date*: 2009-03-04
    Sponsor Name:Hospital of the university of munich
    Full Title: Effect of Iloprost inhalation before and during extracorporeal circulation (ECC) on perioperative morbidity and outcome in high risk cardiac surgical patients
    Medical condition: In this study effects of the intra operative, prophylactic inhalation of Iloprost (Ventavis) before and during extracorporal circulation on perioperative morbidity and outcome in high risk cardiac ...
    Disease: Version SOC Term Classification Code Term Level
    13.1 10038738 - Respiratory, thoracic and mediastinal disorders 10036727 Primary pulmonary hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-002895-15 Sponsor Protocol Number: EPROBRI-2011 Start Date*: 2012-12-19
    Sponsor Name:Fundación Oftalmológica del Mediterráneo
    Full Title: Prophylactic effect of brimonidine on bleeding subconjunctival in 23G vitrectomy
    Medical condition: Subconjunctival haemorrhages after surgery of vitrectomía with 23G
    Disease: Version SOC Term Classification Code Term Level
    15.0 10015919 - Eye disorders 10042341 Subconjunctival haemorrhage LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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