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Clinical trials for Quality of life

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44346   clinical trials with a EudraCT protocol, of which   7374   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    8,245 result(s) found for: Quality of life. Displaying page 1 of 413.
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    EudraCT Number: 2004-004835-72 Sponsor Protocol Number: UB-MedSci-001/2004 Start Date*: 2005-01-12
    Sponsor Name:University of Birmingham [...]
    1. University of Birmingham
    2. University Hospital Birmingham Foundation NHS Trust
    Full Title: A study to determine the effects of growth hormone (GH) replacement therapy on quality of life and cardiovascualr risk in GH deficient adults
    Medical condition: Growth hormone deficiency in adult life
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-021797-10 Sponsor Protocol Number: TIS2012 Start Date*: 2012-01-19
    Sponsor Name:VU university medical center
    Full Title: A phase II randomized multicenter study on efficacy and safety of cultured autologous skin (Tiscover®) and acellular dermal matrix (AS210) in chronic (arterio-)venous ulcers
    Medical condition: The autologous cultured skin substitute (Tiscover) or acellular donor dermis (AS210) is applied to patients with chronic (arterio-) venous leg wounds.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-002880-19 Sponsor Protocol Number: lapaz2006 Start Date*: 2006-09-14
    Sponsor Name:Servicio de psiquiatria. Hospital Universitario La Paz
    Full Title: Comparación de dos estrategias de intervención para el tratamiento de los trastornos depresivos en pacientes oncológicos
    Medical condition: Major depressive Disorder, one episode or several episodes. ICD: 296.2x, 296.3x
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-005424-97 Sponsor Protocol Number: CIGE025EFR02 Start Date*: 2015-01-28
    Sponsor Name:NOVARTIS PHARMA SAS
    Full Title: A phase IV, multicenter, single-arm and open-label study to explore the impact on quality of life of omalizumab (Xolair®) in patients with chronic spontaneous urticaria (CSU) who remain symptomatic...
    Medical condition: chronic spontaneous urticaria
    Disease: Version SOC Term Classification Code Term Level
    18.0 10040785 - Skin and subcutaneous tissue disorders 10072757 Chronic spontaneous urticaria PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2017-000039-16 Sponsor Protocol Number: LUMC-PHEG-20172022 Start Date*: 2017-10-10
    Sponsor Name:Leiden University Medical Center
    Full Title: Paracetamol to enhance quality of life and daily function and to decrease care dependency in advanced dementia: A randomized, double-blind, placebo-controlled crossover trial in long-term care faci...
    Medical condition: We will investigate the effect of regularly scheduled administration of paracetamol on Quality of life, daily functioning, care dependency, pain, change in challenging behaviour and antipsychotic m...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000171288 10066844 Behavioral and psychiatric symptoms of dementia LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001766-25 Sponsor Protocol Number: CASM981CVE01 Start Date*: 2017-09-28
    Sponsor Name:Novartis
    Full Title: An open label, 52 week, multicenter study, of long term management to evaluate effectiveness, tolerability and safety of pimecrolimus cream 1% in pediatric patients with mild to moderate atopic der...
    Medical condition: mild to moderate atopic dermatitis
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2013-004620-10 Sponsor Protocol Number: 719-13 Start Date*: 2014-12-22
    Sponsor Name:Johan Hellgren
    Full Title: A double blind, placebo controlled randomized study of nasal steroid spray treatment on the quality of life and objective sleep parameters in children with sleep disorder breathing.
    Medical condition: Sleep disordered breathing due to enlarged tonsils and/or adenoid
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2020-001824-33 Sponsor Protocol Number: EFC15935 Start Date*: 2020-10-19
    Sponsor Name:Sanofi-Aventis Recherche & Développement
    Full Title: A randomized, multicenter, double-blind phase 3 study of SAR439859 plus palbociclib versus letrozole plus palbociclib for the treatment of patients with ER (+), HER2 (-) breast cancer who have not ...
    Medical condition: ER (+), HER2 (-) breast cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006187 Breast cancer PT
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10028997 Neoplasm malignant PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) GB (GB - no longer in EU/EEA) NL (Prematurely Ended) PT (Prematurely Ended) HU (Prematurely Ended) BE (Completed) PL (Prematurely Ended) FI (Completed) CZ (Completed) AT (Prematurely Ended) BG (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-022938-85 Sponsor Protocol Number: AIO-LQ-0110 Start Date*: 2011-04-27
    Sponsor Name:AIO-Studien-gGmbH
    Full Title: Comparison of two preemptive treatment strategies of panitumumab mediated skin toxicity and assessment of quality of life in patients with Ras-wildtype colorectal cancer
    Medical condition: Panitumumab-mediated Skin toxicity in palliative treatment of Metastatic colorectal cancer with panitumumab
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-003124-12 Sponsor Protocol Number: B-40320109424 Start Date*: 2012-10-30
    Sponsor Name:Cliniques Universitaires Saint Luc
    Full Title: A prospective phase II study on dose escalation using PET based adaptive IMRT stage II-III non small lung cancer
    Medical condition: Stage II-III Non small lung cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2016-002287-14 Sponsor Protocol Number: Reutelen Start Date*: 2016-12-23
    Sponsor Name:Erasmus MC Cancer Institute
    Full Title: Death rattle in the dying phase: is prophylactic treatment useful?
    Medical condition: Death rattle in the dying phase
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004855 10031920 Other diseases of trachea and bronchus, not elsewhere classified LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-002096-96 Sponsor Protocol Number: NL57849.068.16 Start Date*: 2016-09-20
    Sponsor Name:Maastricht University Medical Center
    Full Title: TOPical Imiquimod treatment of high-grade Cervical intraepithelial neoplasia, a multicenter, open-label, non-randomized, controlled study (TOPIC-3 study)
    Medical condition: High-grade Cervical Intraepithelial Neoplasia
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-004926-17 Sponsor Protocol Number: P04879 Start Date*: 2015-04-16
    Sponsor Name:Schering-Plough S.A.de C.V.
    Full Title: OPEN LABEL, 12-WEEK CLINICAL TRIAL TO ASSESS EFFICACY, SAFETY, TREATMENT ADHERENCE AND QUALITY OF LIFE IMPACT ON MOMETASONE FUROATE DRY POWDER 400 MCG ONCE DAILY IN PERSISTENT MILD-MODERATE ASTHMAT...
    Medical condition: Persistent asthma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2007-001889-33 Sponsor Protocol Number: 1790 Start Date*: 2007-08-24
    Sponsor Name:North Bristol NHS Trust
    Full Title: Does an 8 week course of Ambulatory Oxygen Increase Diffuse Parenchymal Lung Diseases Patients Ability to Perform a 6 Minute Walk Test and/or Improve Patients Perception of Quality of Life as measu...
    Medical condition: Patients enrolled will have a diagnosis of restrictive lung disease diagnosed by a High Resolution CT scan, reduced gas transfer result (obtained from pulmonary function tests) and low lung volumes...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10033318 Oxygen saturation decreased LLT
    9.1 10050322 Oxygen supplementation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2020-003671-17 Sponsor Protocol Number: NANOPRO Start Date*: 2021-02-15
    Sponsor Name:Centre François Baclesse
    Full Title: Nanoparticle reirradiation and hypofractionated protontherapy of pan-tumor relapse: non-randomized phase II study.
    Medical condition: recurrent tumors
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10038111 Recurrent cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-005184-15 Sponsor Protocol Number: 05_ENDO_46 Start Date*: 2005-05-24
    Sponsor Name:Christie Hospital NHS Trust
    Full Title: Central Hypothyroidism and Adjusted Thyroxine dose Study (CHATS): impact of increasing free thyroxine levels in patients with hypopituitarism
    Medical condition: Central (secondary/tertiary) hypothyroidism (subclinical)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-001180-36 Sponsor Protocol Number: 2015-2158 Start Date*: 2016-12-01
    Sponsor Name:Rijnstate Hospital
    Full Title: Short-term Efficacy of Stellate Ganglion Block to reduce Hot Flushes
    Medical condition: Hot Flushes
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-004843-22 Sponsor Protocol Number: MK-7339-005 Start Date*: 2020-02-04
    Sponsor Name:Merck Sharp & Dohme Corp.
    Full Title: A Phase 3 Study of Pembrolizumab in Combination with Etoposide/Platinum (Cisplatin or Carboplatin) Followed by Pembrolizumab with or without Maintenance Olaparib in the First-line Treatment of Part...
    Medical condition: Extensive Stage Small Cell Lung Cancer
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10041068 Small cell lung cancer extensive stage PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Prematurely Ended) PL (Completed) ES (Prematurely Ended) FR (Prematurely Ended) BE (Completed) HU (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-001479-22 Sponsor Protocol Number: NCT03021525 Start Date*: 2017-08-04
    Sponsor Name:University Medical Center Hamburg-Eppendorf, Germany
    Full Title: Individualized perioperative hemodynamic goal-directed therapy in major abdominal surgery (iPEGASUS-trial)
    Medical condition: - Hemodynamic Instability - Cardiac Output - High Peroperative Complication
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-003478-29 Sponsor Protocol Number: VIDAFACT Start Date*: 2014-03-21
    Sponsor Name:Maria Nabal Vicuña (Paliative Care Supportive Team-Hospital Universitari Arnau de Vilanova de Lleida)
    Full Title: The effect on quality of life of Vitamin D administration for advanced cancer treatment. A randomized controlled trial
    Medical condition: The effect on quality of life of Vitamin D administration for advanced cancer treatment. A randomized controlled trial
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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