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Clinical trials for Saline placebo

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    132 result(s) found for: Saline placebo. Displaying page 1 of 7.
    1  2  3  4  5  6  7  Next»
    EudraCT Number: 2008-005120-86 Sponsor Protocol Number: 112077 Start Date*: 2009-01-08
    Sponsor Name:GlaxoSmithKline Biologicals
    Full Title: A phase II, observer-blind, randomised, placebo-controlled, adjuvant-dose selection, multicenter prophylactic vaccination study to evaluate the immunogenicity and safety of GSK Biologicals’ herpes ...
    Medical condition: Primary immunisation of subjects aged 50 years or older against herpes zoster (HZ). The study population includes healthy volunteer males and females in the age ranges: 50-59 years of age (YOA), 6...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2005-005519-12 Sponsor Protocol Number: V59P11 Start Date*: 2006-03-13
    Sponsor Name:CHIRON
    Full Title: A Phase 3, Multi-Center, Observer Blind, Controlled, Randomized Study to Compare the Immunogenicity and Safety of the Concomitant Administration of a Combined Tetanus, Reduced Diphtheria, and Acell...
    Medical condition: Active profilaxys against Neisseria Mengitidis type A, C, W, Y
    Disease: Version SOC Term Classification Code Term Level
    6.1 10027249 PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2014-001155-22 Sponsor Protocol Number: Lap2014NMB Start Date*: 2014-05-22
    Sponsor Name:Mona Ring Gätke
    Full Title: Muscle relaxation during open upper abdominal surgery -can the surgical conditions be optimized? (The laparotomy study)
    Medical condition: The aim of the study is to investigate if intense NMB improves surgical conditions during operation in patients scheduled for elective open upper abdominal surgery.
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004865 10023697 Laparotomy & drainage LLT
    17.0 100000004865 10051777 Staging laparotomy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2006-004252-20 Sponsor Protocol Number: VITRIS.at Start Date*: 2010-09-03
    Sponsor Name:Medizinische Universität Innsbruck - Univ.-Klinik für Anästhesie und Allgemeine Intensivmedizin
    Full Title: A Multicenter, Randomized, Controlled Trial Assessing Arginine Vasopressin vs. Saline Placebo in Refractory Traumatic Hemorrhagic Shock Patients (VITRIS.at-Study)
    Medical condition: The purpose of the trial is to assess effects of arginine vasopressin vs. saline placebo on hospital admission rate and hospital discharge rate in presumed traumatic hemorrhagic shock patients afte...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10044541 Traumatic shock LLT
    9.1 10044541 Traumatic shock PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-003996-35 Sponsor Protocol Number: IPERBRO Start Date*: 2005-02-01
    Sponsor Name:UNIVERSITA DEGLI STUDI DI UDINE
    Full Title: randomized,double blind, placebo-controlled trial of the effect of treatment with 3 hypertonic salin solution on bronchiolitis
    Medical condition: Nebulized 3 hypertonic saline solution to improve clinical outcomes in children with bronchiolitis
    Disease: Version SOC Term Classification Code Term Level
    6.1 10062106 PT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-003509-18 Sponsor Protocol Number: NAC0606 Start Date*: 2007-08-13
    Sponsor Name:University of Edinburgh [...]
    1. University of Edinburgh
    2. NHS Lothian Health Board
    Full Title: Mechanisms for the effect of acetylcysteine on renal function after exposure to radiographic contrast material
    Medical condition: Radiocontrast-induced nephropathy
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-005077-52 Sponsor Protocol Number: 2013LIDO Start Date*: 2015-05-07
    Sponsor Name:Dra. Antònia Dalmau i Llitjós. Servicio de Anestesia, Reanimación y Terapéutica del Dolor del HUB-Idibell
    Full Title: Double-Blind Randomized Clinical trial to assess the pain reduction in wound healing with previous application of cutaneous lidocaine solution versus placebo
    Medical condition: Evaluate pain reduction during wound cleaning after previous application of topic solution of lidocaine vs. placebo
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001636-19 Sponsor Protocol Number: HTX-011-302 Start Date*: 2017-09-15
    Sponsor Name:Heron Therapeutics, Inc.
    Full Title: A Phase 3, Randomized, Double-Blind, Saline Placebo- and Active-Controlled, Multicenter Study of HTX-011 via Local Administration for Postoperative Analgesia and Decreased Opioid Use Following Unil...
    Medical condition: Postoperative Analgesia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2016-001668-13 Sponsor Protocol Number: GE-012-106 Start Date*: 2017-10-25
    Sponsor Name:GE Healthcare Ltd. and its Affiliates
    Full Title: Parallel-Group, Placebo-Controlled Randomized Study Investigating the Effect of Intravenous Iso-osmolar Iodinated Contrast Material Iodixanol (Visipaque™ Injection 320 mgI/mL) on Renal Function in ...
    Medical condition: Chronic Kidney Disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000070575 10076410 Chronic kidney disease stage 3 LLT
    20.0 100000070575 10076411 Chronic kidney disease stage 4 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended) GB (Prematurely Ended) BE (Prematurely Ended) HU (Completed) PL (Prematurely Ended) NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-004034-38 Sponsor Protocol Number: MK-7684A-002 Start Date*: 2021-04-19
    Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc
    Full Title: A Phase 2, Multicenter, Randomized Study to Compare the Efficacy and Safety of MK-7684A or MK-7684A Plus Docetaxel Versus Docetaxel Monotherapy in the Treatment of Participants With Metastatic Non-...
    Medical condition: Non Small Cell Lung cancer
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10059515 Non-small cell lung cancer metastatic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Trial now transitioned) DK (Trial now transitioned) DE (Trial now transitioned) BE (Trial now transitioned) AT (Trial now transitioned) PL (Trial now transitioned) FR (Trial now transitioned) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2008-003886-17 Sponsor Protocol Number: NL21828 Start Date*: 2008-12-08
    Sponsor Name:VieCuri Medisch Centrum voor Noord-Limburg
    Full Title: Effect of inhaled hypertonic saline solution to treat infants hospitalized with viral bronchiolitis.
    Medical condition: Acute viral bronchiolitis (an infection of the lower airways) in infants under two years of age. This is usually caused by Respiratory Syncytial Virus (RSV). The diagnosis of viral bronchiolitis wi...
    Disease:
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-003870-88 Sponsor Protocol Number: MUKO-D-GSH-4 Start Date*: 2006-10-20
    Sponsor Name:Mukoviszidose Institut gGmbH i. G.
    Full Title: Randomized, placebo-controlled, double-blind study to investigate the efficacy and safety of a 24-week inhalation treatment with glutathione in cystic fibrosis patients
    Medical condition: Cystic fibrosis (CF) is the most common autosomal recessive lethal hereditary disorder in Caucasians. The majority of cystic fibrosis patients die as a result of progressive pulmonary disease. Airw...
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-002585-23 Sponsor Protocol Number: ANJ-02-2015 Start Date*: 2016-01-08
    Sponsor Name:Medicinsk Forskningsafsnit, Regionshospitalet Holstebro (Department of Medical Research, Regional Hospital Holstebro)
    Full Title: The effect of 3% NaCl and furosemid on biomarkers and the kidneys managment of sodium and water, vasoactive hormones and GFR in healthy subjects.
    Medical condition: Healthy volunteers (The effect of flurosemide, together with an infusion of hypertone saline, on the kidneys, using biomarkers)
    Disease: Version SOC Term Classification Code Term Level
    18.1 10022891 - Investigations 10022891 Investigations SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-002784-21 Sponsor Protocol Number: 20210516 Start Date*: 2022-04-01
    Sponsor Name:Västra Götalandsregionen
    Full Title: Botulinum toxin type A as treatment for chronic myogenous orofacial pain - a radomized controlled, double-blind clinical trial
    Medical condition: Chronic myalgia (>6months) in the facial region.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2017-004188-11 Sponsor Protocol Number: MK-3475-789 Start Date*: 2018-05-09
    Sponsor Name:Merck Sharp & Dohme LLC
    Full Title: A Randomized, Double-Blind, Phase 3 Study of Pemetrexed + Platinum Chemotherapy with or without Pembrolizumab (MK-3475) in TKI-resistant EGFR-mutated Tumors in Metastatic Non-squamous Non-small Cel...
    Medical condition: Metastatic Non-squamous Non-small Cell Lung Cancer
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029522 Non-small cell lung cancer stage IV PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) ES (Completed) FR (Completed) DE (Completed) GB (GB - no longer in EU/EEA) IT (Completed)
    Trial results: View results
    EudraCT Number: 2015-005757-12 Sponsor Protocol Number: FAIR-HFpEF Start Date*: 2017-06-06
    Sponsor Name:Charité – Universitätsmedizin Berlin
    Full Title: Effect of IV iron (ferric carboxymaltose, Ferinject) on exercise tolerance, symptoms and quality of life in patients with heart failure with preserved ejection fraction (HFpEF) and iron deficiency ...
    Medical condition: Patients with heart failure with preserved ejection fraction (HFpEF) and iron deficiency (ID) with and without anaemia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-004841-13 Sponsor Protocol Number: VX15-371-101 Start Date*: 2016-08-08
    Sponsor Name:Vertex Pharmaceuticals Inc.
    Full Title: A Phase 2a, Randomized, Double-blind, Placebo-controlled, Incomplete Block, Crossover Study to Evaluate the Safety and Efficacy of VX-371 in Subjects Aged 12 Years or Older With Cystic Fibrosis, Ho...
    Medical condition: Cystic Fibrosis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10011762 Cystic fibrosis PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IE (Completed) GB (Completed) FR (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2019-002124-32 Sponsor Protocol Number: CUSA-081-HEM-01 Start Date*: 2020-01-02
    Sponsor Name:Chiesi Farmaceutici S.p.A.
    Full Title: READY 1: A Phase 3, Randomized, Double-Blind, Active and Placebo-Controlled Study on the use of CUSA-081 for Dysfunctional Central Venous Access Devices (CVADs)
    Medical condition: Catheter Occlusion Thrombosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) BE (Completed) ES (Prematurely Ended) RO (Ongoing)
    Trial results: View results
    EudraCT Number: 2006-004565-33 Sponsor Protocol Number: EASI Start Date*: 2006-11-16
    Sponsor Name:Chemische Fabrik Kreussler & Co.GmbH
    Full Title: Efficacy and safety of Aethoxysklerol compared to Sodium Tetradecyl Sulfate and Isotonic Saline (placebo) for the treatment of reticular veins and spider veins including subgroup to investigate the...
    Medical condition: Patients suffering from varicose veins (spider veins or reticular veins in the legs) should be treated with a sclerosing agent.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10047001 Varicose veins LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-000390-31 Sponsor Protocol Number: HyperHAES-PÄD-CARDIO-02 Start Date*: 2007-10-30
    Sponsor Name:Universitätsklinikum Erlangen
    Full Title: Application of hypertonic hyperoncotic solutions for improvement of cardiac output after open heart surgery in children - monocentric, randomised, placebo controlled, double-blind clinical trial (p...
    Medical condition: Children after open-heart surgery for congenital cardiac disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019273 Heart disease congenital LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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