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Clinical trials for Serotonergic

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    27 result(s) found for: Serotonergic. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2004-005103-16 Sponsor Protocol Number: ETF 5450 Start Date*: 2005-02-09
    Sponsor Name:Estonian Science Foundation
    Full Title: Central serotonergic activity measured by citalopram challenge test and platelet monoamine oxidase activity, associations with gene polymorphism (5-HTTLPR) and impulsivity
    Medical condition: Healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: EE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-011824-79 Sponsor Protocol Number: 91686125 Start Date*: 2009-11-03
    Sponsor Name:Academic Medical Center
    Full Title: Effects of fluoxetine on the outgrowth of the serotonergic system
    Medical condition: We investigate whether the effects fluoxetine (Prozac®) on the outgrowth of the serotonergic system are dependent on age. In a 16 week multicenter randomized, double-blind, placebo controlled trial...
    Disease: Version SOC Term Classification Code Term Level
    15.0 10022891 - Investigations 10056941 MRI brain LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-001990-25 Sponsor Protocol Number: BO1 Start Date*: 2004-09-06
    Sponsor Name:Bo Söderpalm
    Full Title: Hur påverkar Remeron alkoholkonsumtionen? How will Remeron influence alcohol consumption in high consumers?
    Medical condition: The subjects in the study will be recruited via an advertisment and will not have a diagnos. We will include males with high consumption of alcohol, defines as 400 grams or more of 100% alcohol per...
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002677-24 Sponsor Protocol Number: self sponsored Start Date*: 2005-03-07
    Sponsor Name:Karolinska Institutet, Institutionen för klinisik neurovetenskap, sektion för psykiatri
    Full Title: Hormonersättningseffekt på serotoninåterupptag hos ooforektomerade kvinnor
    Medical condition: Bilateral oophorectomy and hysterectomy and a wish for hormonal replacement therapy afterwards.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2020-002908-39 Sponsor Protocol Number: FEPODPara2020-1 Start Date*: 2020-10-30
    Sponsor Name:Helsinki University Hospital
    Full Title: Detection of paracetamol concentration in blood-, saline- and urine samples with an electrochemical indicator in healthy volunteers - a validation study for a novel technique.
    Medical condition: This is a laboratory equipment validation study. All subjects are healthy volunteered individuals.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2012-004579-37 Sponsor Protocol Number: MZ12-PCP-PalenicekTomas-A Start Date*: 2014-06-18
    Sponsor Name:National Institute of Mental Health
    Full Title: Animal and human serotonergic model of schizophrenia: validity evaluated by qEEG and fMRI
    Medical condition: Inclusion criteria: a) Men and women at age between 28 and 65 years b) healthy volunteers with negative psychiatric history (severe mental illnesses that meet the criteria of ICD 10 F0.X - F99.X) ...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004156-39 Sponsor Protocol Number: no sponsor Start Date*: 2005-11-18
    Sponsor Name:Dept. of Neurology Vienna
    Full Title: Brain serotonin 5-HT1A receptor binding in human mesial temporal lobe epilepsy measured by positron emission tomography and [11C]WAY-100635
    Medical condition: Application of [11C]WAY-100635, a brain serotonin 5-HT1A receptor ligand, in patients with mesial temporal lobe epilepsy
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2006-002342-11 Sponsor Protocol Number: D1449L00033 Start Date*: 2007-04-19
    Sponsor Name:Klinikum Fulda gAG
    Full Title: Multicenter study of neurotransmitters and neuropeptides in schizophrenia: A multidisciplinary study of biological, pharmacokinetic, receptor occupancy and clinical relationships in patients suffer...
    Medical condition: Patients have to fulfill the diagnostic criteria of a schizophrenia according to DSM-IV.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-001450-66 Sponsor Protocol Number: 2007-001450-66 Start Date*: 2007-09-26
    Sponsor Name:Karolinska Institutet
    Full Title: Improved management of depression in primary health care – a randomized study of two structured programs with reference to the role of genetic predisposition
    Medical condition: To evaluate different treatment alternatives, including psychological intervention, in depressed patients recruited by screening in participating GP:s waiting-rooms (opportunistic screening). In o...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-006206-27 Sponsor Protocol Number: Gra-geneticver1 Start Date*: 2012-02-21
    Sponsor Name:Karolinska Institutet
    Full Title: Does 5-HT polymorphism contribute to pain regulation and efficacy of granisetron?
    Medical condition: Experimentally induced muscle pain in healthy volunteers, both sexes and over 18 years of age.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2013-000426-62 Sponsor Protocol Number: CHDR1203-E Start Date*: 2013-04-10
    Sponsor Name:Centre for Human Drug Research
    Full Title: A randomized, double blind, placebo-controlled crossover study to investigate the effects of a selective serotonergic reuptake inhibitor on resting state fMRI in healthy volunteers.
    Medical condition: healthy volunteers 'depression, anxiety'
    Disease: Version SOC Term Classification Code Term Level
    15.1 10037175 - Psychiatric disorders 10012378 Depression PT
    15.1 10037175 - Psychiatric disorders 10002855 Anxiety PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2005-006151-20 Sponsor Protocol Number: D1449L00029 Start Date*: 2006-08-29
    Sponsor Name:University of Erlangen-Nuremberg
    Full Title: Quetiapine and the dopaminergic epigenetic control – a pilot study
    Medical condition: Patients suffering from schizophrenia (ICD10: F20.x) Healthy controls
    Disease: Version SOC Term Classification Code Term Level
    8.1 10039628 Schizophrenia and other psychotic disorders HLGT
    Population Age: Adults Gender: Male
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-018016-25 Sponsor Protocol Number: MAJKT1 Start Date*: 2010-04-29
    Sponsor Name:Academic Medical Center
    Full Title: Dopamine-serotonin dysbalance in patients with dystonia
    Medical condition: Dystonia
    Disease: Version SOC Term Classification Code Term Level
    12.1 10013983 Dystonia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-013061-26 Sponsor Protocol Number: DuloTram_1.0 Start Date*: 2009-07-14
    Sponsor Name:University of Turku
    Full Title: Efficacy, safety, tolerability and pharmacokinetics of concomitant administration of tramadol with duloxetine or pregabalin: a randomized controlled flexible-dose study in patients with neuropathic...
    Medical condition: G53.0 Vyöruusun jälkeinen hermosärky G63.2 Diabeteksen monihermosairaus
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036377 Postherpetic polyneuropathy LLT
    9.1 10012680 Diabetic neuropathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-015165-31 Sponsor Protocol Number: EME-08/43/39 Start Date*: 2010-07-16
    Sponsor Name:Northumberland, Tyne and Wear NHS Foundation Trust
    Full Title: Antiglucocorticoid augmentation of antiDepressants in Depression: a double-blind, randomised, placebo-controlled, parallel-group trial
    Medical condition: depression
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-005506-32 Sponsor Protocol Number: Dulo2006 Start Date*: 2007-03-05
    Sponsor Name:Danish Pain Research Center
    Full Title: Pain, anxiety and depression in neuropathic and non-neuropathic pain: Effect of monoamine modulation.
    Medical condition: Chronic pain: neuropathic pain and fibromyalgia
    Disease: Version SOC Term Classification Code Term Level
    8.1 10033371 Pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-000526-31 Sponsor Protocol Number: BT2006003 Start Date*: 2007-01-03
    Sponsor Name:Section of Clinical Pain Research, Department of Molecular Medicine and Surgery Karolinska Institute
    Full Title: Brush-evoked allodynia in patients with peripheral neuropathy before and following intravenous infusion of ondansetron. A randomised, double-blind, placebo controlled, cross-over study.
    Medical condition: Peripheral neuropathy
    Disease: Version SOC Term Classification Code Term Level
    8.1 10029331 Neuropathy peripheral LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2014-005422-35 Sponsor Protocol Number: Start Date*: 2015-05-28
    Sponsor Name:Imperial College London-Imperial College Healthcare NHS Trust
    Full Title: THE ROLE OF BUSPIRONE IN ATTENUATING LEVODOPA-INDUCED DYSKINESIAS IN PATIENTS WITH PARKINSON'S DISEASE: A CLINICAL AND POSITRON EMISSION TOMOGRAPHY STUDY WITH 11C-PHNO.
    Medical condition: Levodopa induced dyskinesias within Parkinson's disease.
    Disease: Version SOC Term Classification Code Term Level
    17.1 10029205 - Nervous system disorders 10061536 Parkinson's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-005292-17 Sponsor Protocol Number: TRx-237-008 Start Date*: 2012-10-02
    Sponsor Name:TauRx Therapeutics Ltd
    Full Title: A Double-Blind, Placebo-Controlled, Randomised, 4-Week Safety and Tolerability Study of LMTM in Subjects with Mild to Moderate Alzheimer’s Disease on Pre-Existing Stable Acetylcholinesterase Inhibi...
    Medical condition: Alzheimer’s Disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004852 10001896 Alzheimer's disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-002007-29 Sponsor Protocol Number: 42165279MDD2001 Start Date*: 2015-11-24
    Sponsor Name:Janssen-Cilag International NV
    Full Title: A Phase 2a Randomized, Double-blind, Placebo-Controlled, Parallel-Group, Multi-center Study Investigating the Efficacy, Safety, and Tolerability of JNJ-42165279 in Subjects with Major Depressive Di...
    Medical condition: Major Depressive Disorder Anxiety
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004873 10025453 Major depressive disorder NOS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed) GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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