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Clinical trials for Sodium bicarbonate

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    100 result(s) found for: Sodium bicarbonate. Displaying page 1 of 5.
    1  2  3  4  5  Next»
    EudraCT Number: 2006-002770-22 Sponsor Protocol Number: SOB06 Start Date*: 2006-09-26
    Sponsor Name:York Hospital NHS Trust
    Full Title: The effects of oral sodium bicarbonate on extracellular water in patients with chronic renal failure
    Medical condition: We will investiagte the use of sodium bicarbonate on extracellular water in patients with CHRONIC RENAL FAILURE
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-001439-20 Sponsor Protocol Number: 15HH2613 Start Date*: 2015-07-30
    Sponsor Name:Imperial College Healthcare NHS Trust and Imperial College London
    Full Title: A Feasibility Randomised Controlled Trial: Effects of Oral Sodium Bicarbonate Supplementation in Patients on Haemodialysis
    Medical condition: End stage renal disease and metabolic acidosis with renal replacement therapy of haemodialysis.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-012199-29 Sponsor Protocol Number: 2080 Start Date*: 2009-07-20
    Sponsor Name:North Bristol NHS Trust Research and Development Office [...]
    1. North Bristol NHS Trust Research and Development Office
    2.
    Full Title: 8.4% sodium bicarbonate v 5% sodium chloride for raised intracranial pressure - a randomised controlled trial.
    Medical condition: Intracranial hypertension with coma after severe head injury
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-001838-29 Sponsor Protocol Number: TEATE Start Date*: 2015-01-08
    Sponsor Name:"G. d'Annunzio" University
    Full Title: PrevenTion of contrast‐inducEd nephroAThy with urinE alkalinization: the TEATE study
    Medical condition: contrast‐induced nephroathy
    Disease: Version SOC Term Classification Code Term Level
    17.0 10022117 - Injury, poisoning and procedural complications 10010836 Contrast media reaction PT
    17.0 10038359 - Renal and urinary disorders 10029155 Nephropathy toxic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-002037-38 Sponsor Protocol Number: NL44415.078.13 Start Date*: 2013-10-29
    Sponsor Name:
    Full Title: The effect of correction of metabolic acidosis in chronics kidney disease on intrarenal RAS activity.
    Medical condition: Metabolic acidosis in chronic kidney disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-002223-32 Sponsor Protocol Number: E2007-0507 Start Date*: Information not available in EudraCT
    Sponsor Name:Charité Universitaetsmedizin
    Full Title: A multicentre, double-blind, randomised placebo-controlled trial of sodium bicarbonate to prevent acute kidney injury in patients undergoing cardiopulmonary bypass surgery.
    Medical condition: Cardiac surgical patients in whom the use of cardiopulmonary bypass is planned and having at least one ore more of the following risk factors for post-operative acute kidney injury • Age ≥ 70 years...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) IE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2021-001665-20 Sponsor Protocol Number: BCAR-RESP-SE21 Start Date*: 2021-04-20
    Sponsor Name:Semmelweis University Department of Oralbiology
    Full Title: Prospective, randomized, controlled, double-blinded study on the efficacy of nebulized 4.2% sodium-bicarbonate in COVID-19 pneumonia
    Medical condition: severe COVID-19 pneumonia requires invasive ventillatory support
    Disease: Version SOC Term Classification Code Term Level
    23.1 100000004862 10084564 SARS-CoV-2 pneumonia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-004033-25 Sponsor Protocol Number: PED-FQ-2016 Start Date*: 2017-06-19
    Sponsor Name:Fundació Parc Taulí
    Full Title: Efect of nebulized bicarbonate on bacterial infections in patients with cystic fibrosis. Randomized clinical trial
    Medical condition: Cystic Fibrosis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10074550 Preventive antimicrobial therapy in cystic fibrosis LLT
    20.0 100000004850 10011764 Cystic fibrosis NOS LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006948-65 Sponsor Protocol Number: Version 4 Start Date*: 2007-11-29
    Sponsor Name:University Hospitals of Leicester NHS Trust
    Full Title: The effect of acidosis correction and exercise on tissue wasting and immune function in renal patients
    Medical condition: Chronic kidney disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-005271-16 Sponsor Protocol Number: 2010NE02 Start Date*: 2012-11-29
    Sponsor Name:University of Dundee & NHS Tayside
    Full Title: Does oral sodium bicarbonate therapy improve function and quality of life in older patients with chronic kidney disease and low-grade acidosis? A multicentre randomized placebo controlled trial
    Medical condition: Chronic kidney disease stages 4/5 with metabolic acidosis
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004857 10064848 Chronic kidney disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-006413-25 Sponsor Protocol Number: GA0821 Start Date*: 2008-12-09
    Sponsor Name:Reckitt Benckiser Healthcare (UK) Limited
    Full Title: A single-centre randomised, partially blind, single dose, crossover study investigating the onset of action of soothing and cooling after taking Gaviscon Peppermint liquid, Double Action Gaviscon ...
    Medical condition: Symptoms of heartburn
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-000219-14 Sponsor Protocol Number: 1957 Start Date*: 2008-03-19
    Sponsor Name:North Bristol NHS Trust
    Full Title: Efficacy of 8.4% sodium bicarbonate in adult patients with closed head injuries and intracranial hypertension.
    Medical condition: Raised intracranial pressure after severe head injury.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10022764 Intracranial hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2011-005575-16 Sponsor Protocol Number: BufferedTumescenceV3 Start Date*: 2011-12-21
    Sponsor Name:Hull & East Yorkshire Hospitals NHS Trust
    Full Title: Tumescent Anaesthesia in Endovenous Laser Ablation of Varicose Veins: A Randomised Controlled Trial of a Buffered Tumescent Solution
    Medical condition: Pain of injection of a tumescent anaesthetic solution used during EndoVenous Laser Ablation of Varicose Veins.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-005821-31 Sponsor Protocol Number: GA0706 Start Date*: 2008-01-15
    Sponsor Name:Reckitt Benckiser Healthcare UK) Limited [...]
    1. Reckitt Benckiser Healthcare UK) Limited
    2. Reckitt Benckiser Healthcare (UK) Limited
    Full Title: A single-centre randomised, partially blind, single dose, crossover pilot study investigating the use of stopwatches to assess the onset of action of soothing and cooling of Gaviscon Peppermint Liq...
    Medical condition: Symptoms of heartburn
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-001216-38 Sponsor Protocol Number: 67369 Start Date*: 2019-06-12
    Sponsor Name:Hvidovre Hospital, Region Hovedstaden
    Full Title: Measurement of systemic pH and lactate in labouring women after intake of bicarbonate.
    Medical condition: A successful Labour is dependent on the ability of the uterus to produce co-ordinated contractions that are of both the right duration and intensity. A failure to produce these can result in an arr...
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004868 10036873 Prolonged labour, unspecified LLT
    Population Age: Adults Gender: Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2009-013547-11 Sponsor Protocol Number: 09-059 Start Date*: 2009-07-16
    Sponsor Name:Leids Universitair Medisch Centrum
    Full Title: Sodium Bicarbonate for the prevention of Contrast Induced Nephropathy in patients undergoing CTPA
    Medical condition: The prevention of Contrast Induced Nephropathy is under investigation. Contrast induced nephropathy (CIN) can occur after injecting radiographic iso osmolair contrast media. Patients with a renal i...
    Disease: Version SOC Term Classification Code Term Level
    12.0 10037790 Radiocontrast nephropathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-001824-36 Sponsor Protocol Number: 201201 Start Date*: 2012-07-12
    Sponsor Name:Medical University of Vienna, Department of Medicine III, Division of Nephrology und Dialysis
    Full Title: ORAL SODIUM BICARBONATE SUPPLEMENTATION IN PATIENTS WITH CHRONIC METABOLIC ACIDOSIS AND CHRONIC KIDNEY DISEASE
    Medical condition: Patients classified to have chronic kidney disease of stage 3 and 4 and chronic metabolic acidosis (venous serum HCO3- of <21mml/L on 2 separate measurements at least 1 day apart) should be include...
    Disease: Version SOC Term Classification Code Term Level
    21.0 10027433 - Metabolism and nutrition disorders 10066569 Chronic acidosis LLT
    23.1 10038359 - Renal and urinary disorders 10064848 Chronic kidney disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-003073-15 Sponsor Protocol Number: 0504 Start Date*: 2016-02-12
    Sponsor Name:Research Governance, University of Leicester
    Full Title: HYDration and bicarbonate to prevent acute Renal injury after endovascular Aneurysm repair: pilot-feasibility randomized controlled study (HYDRA pilot trial)
    Medical condition: Acute kidney injury post endovascular repair of the abdominal aortic aneurysm.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004866 10000051 Abdominal aneurysm LLT
    20.0 100000004866 10000054 Abdominal aortic aneurysm LLT
    20.0 10038359 - Renal and urinary disorders 10069339 Acute kidney injury PT
    20.0 10038359 - Renal and urinary disorders 10068736 Acute oliguric renal failure LLT
    20.1 10038359 - Renal and urinary disorders 10001041 Acute renal failure LLT
    20.0 10038359 - Renal and urinary disorders 10001051 Acute renal failure, unspecified LLT
    20.0 10038359 - Renal and urinary disorders 10070787 Anuric renal failure LLT
    20.0 10038359 - Renal and urinary disorders 10068736 Acute oliguric renal failure LLT
    20.1 10038359 - Renal and urinary disorders 10001041 Acute renal failure LLT
    20.0 10038359 - Renal and urinary disorders 10001051 Acute renal failure, unspecified LLT
    20.0 10038359 - Renal and urinary disorders 10070787 Anuric renal failure LLT
    20.0 10042613 - Surgical and medical procedures 10061657 Arterial stent insertion PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-001033-18 Sponsor Protocol Number: 06ANA001 Start Date*: 2006-05-22
    Sponsor Name:Chelsea and Westminster Hospital
    Full Title: Extending low-dose epidural for emergency Caesarean section - a comparison of bicarbonated lidocaine with 0.5% levobupivacaine
    Medical condition: N/A
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-002032-33 Sponsor Protocol Number: NICIR Start Date*: 2016-07-20
    Sponsor Name:Fundacio Privada Clinic per a la Recerca Biomedica
    Full Title: Comparative study of the efficacy of oral versus intravenous hydration as a preventive measure of contrast-induced nephropathy (CIN) in patients with renal insufficiency (RI) grade III under study ...
    Medical condition: Patients with renal failure undergoing a computed tomography scan with contrast
    Disease: Version SOC Term Classification Code Term Level
    19.0 10038359 - Renal and urinary disorders 10038435 Renal failure PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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