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Clinical trials for Solid organ transplantation

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
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    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    60 result(s) found for: Solid organ transplantation. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2018-003640-23 Sponsor Protocol Number: IRRB/05/18 Start Date*: 2019-05-29
    Sponsor Name:ISTITUTO MEDITERRANEO PER I TRAPIANTI E TERAPIE AD ALTA SPECIALIZZAZIONE - ISMETT
    Full Title: USE OF HEPATITIS C+ DONORS FOR SOLID ORGAN TRANSPLANTATION IN A GEOGRAPHICAL AREA WITH HCV+ ENDEMIC INFECTION AND WITH A LOW-RATE CADAVERIC ORGAN DONOR AVAILABILITY. A PHASE II OPEN, MONOCENTRIC CL...
    Medical condition: USE OF POSITIVE DONORS FOR INFECTION OF THE HEPATITIS VIRUS FOR THE TRANSPLANTATION OF SOLID ORGANS IN AN ENDEMIC AREA FOR HEPATITIS C WITH LOW RATE OF DONATIONS FROM CADAVERS: OPEN PHASE II CLINI...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10024714 Liver transplant PT
    21.1 10047065 - Vascular disorders 10063837 Reperfusion injury PT
    20.1 10022117 - Injury, poisoning and procedural complications 10058060 Graft complication PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-012258-19 Sponsor Protocol Number: F506-CL-0403 Start Date*: 2011-03-09
    Sponsor Name:Astellas Pharma Europe Ltd.
    Full Title: A Multicentre, Open-label, Pharmacokinetic Study of Modigraf® (Tacrolimus granules) in de novo Paediatric Allograft Recipients.Estudio Abierto, Multicéntrico, Farmacocinético de Modigraf® (Tacróli...
    Medical condition: De novo allograft transplantation (liver, heart, kidney) in paediatric patients. Pacientes pediátricos que reciben un trasplante de aloinjerto de novo ( hígado, corazón y riñón)
    Disease: Version SOC Term Classification Code Term Level
    13.1 10042613 - Surgical and medical procedures 10024716 Liver transplantation LLT
    13.1 10042613 - Surgical and medical procedures 10019314 Heart transplant PT
    13.1 10042613 - Surgical and medical procedures 10023438 Kidney transplant LLT
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Completed) GB (Completed) DE (Completed) BE (Completed) FR (Ongoing)
    Trial results: View results
    EudraCT Number: 2014-003561-15 Sponsor Protocol Number: MYSTEP1 Start Date*: 2016-08-30
    Sponsor Name:University Hospital of Tuebingen
    Full Title: Safety and Tolerance of Immunomodulating Therapy with Donor-specific Mesenchymal Stem Cells in Pediatric Living-Donor Liver Transplantation
    Medical condition: Side effects of life-long immunosuppressive medication account for major morbidity after pediatric liver transplantation and impair quality of life. In-vivo and in-vitro studies have shown that MSC...
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004865 10024716 Liver transplantation LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-001974-27 Sponsor Protocol Number: STOPFLU Start Date*: 2019-10-15
    Sponsor Name:Centre Hospitalier Universitaire Vaudois (CHUV)
    Full Title: Reducing the Burden of Influenza after Solid-Organ Transplantation: the STOP-FLU trial [Swiss Trial in solid Organ transplantation on Prevention of inFLUenza]
    Medical condition: Influenza in solid organ transplant patients
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10022000 Influenza PT
    21.1 10042613 - Surgical and medical procedures 10061890 Organ transplant PT
    21.1 10042613 - Surgical and medical procedures 10059429 Influenza immunisation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-003243-21 Sponsor Protocol Number: TRANSGRIPE 1-2 Start Date*: 2011-10-17
    Sponsor Name:Fundación Pública Andaluza Progreso y Salud
    Full Title: Randomized, comparative and prospective clinical trial evaluating efficacy and safety of a dose of seasonal flu vaccine compared to two doses of vaccine for prevention of influenza in solid organ t...
    Medical condition: seasonal influenza prophylaxis in trasplant receipiens
    Disease: Version SOC Term Classification Code Term Level
    14.0 10021881 - Infections and infestations 10021829 Infection in solid organ transplant recipients LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2017-004322-15 Sponsor Protocol Number: V503-IC Start Date*: 2018-02-09
    Sponsor Name:UZ Leuven
    Full Title: An Open-label phase III study to investigate the safety, tolerability and immunogenicity of a nine-valent human papillomavirus (HPV) vaccine (Gardasil®9) in solid organ transplant recipients and HI...
    Medical condition: Immune response to HPV vaccination in HIV-patients and Solid Organ Transplant patients
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004870 10074286 Immunocompromised LLT
    20.0 100000004848 10020180 HIV positive LLT
    20.0 100000004865 10023438 Kidney transplant LLT
    20.0 100000004865 10007611 Cardiac transplant LLT
    20.0 100000004865 10019248 Heart & lung transplant LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2009-012436-32 Sponsor Protocol Number: IVIST01 Start Date*: Information not available in EudraCT
    Sponsor Name:Medizinische Hochschule Hannover
    Full Title: A multicenter, randomized, open-labeled study to steer immunsuppressive and antiviral therapy by measurement of virus- (CMV, ADV, HSV) specific T cells in addition to determination of trough levels...
    Medical condition: After solid organ transplantation immunosuppressive treatment disrupts the individual balance between virus-replication and cellular immune response. This can lead to an elevated risk of severe vir...
    Disease: Version SOC Term Classification Code Term Level
    19.1 10042613 - Surgical and medical procedures 10052279 Renal and liver transplant PT
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-012259-21 Sponsor Protocol Number: F506-CL-0404 Start Date*: 2011-03-02
    Sponsor Name:Astellas Pharma Europe Ltd.
    Full Title: A Long-term, Open-label, Non-comparative Study to Evaluate the Safety and Efficacy of a Modigraf® Based Immunosuppression Regimen in Paediatric Solid Allograft Recipients.Estudio abierto, no compar...
    Medical condition: Stable paediatric allograft recipients.Pacientes estables receptores de un aloinjerto
    Disease: Version SOC Term Classification Code Term Level
    12.1 10050432 Prophylaxis against heart transplant rejection LLT
    12.1 10050434 Prophylaxis against liver transplant rejection LLT
    12.1 10050436 Prophylaxis against renal transplant rejection LLT
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Prematurely Ended) GB (Prematurely Ended) DE (Prematurely Ended) BE (Completed) FR (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-002784-18 Sponsor Protocol Number: 13005 Start Date*: 2018-07-24
    Sponsor Name:Clinical Trials and Research Governance
    Full Title: Safety and efficacy of Tofacitinib in ameliorating ischaemia reperfusion injury and allograft pancreatitis in solid organ transplantation – a pilot study
    Medical condition: Ischaemia reperfusion injury and allograft pancreatitis.
    Disease: Version SOC Term Classification Code Term Level
    20.1 10017947 - Gastrointestinal disorders 10066127 Ischaemic pancreatitis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2013-000793-30 Sponsor Protocol Number: PedTac Start Date*: 2013-10-22
    Sponsor Name:Oslo University Hospital - Rikshospitalet
    Full Title: The PedTac study Development of a pediatric pharmacokinetic population model for Tacrolimus
    Medical condition: Solid organ transplantation
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004870 10052779 Transplant rejections HLT
    16.0 100000004848 10043411 Therapeutic drug monitoring analyses HLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NO (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-004479-11 Sponsor Protocol Number: DPTLDSG-IIT-PTLD-2 Start Date*: 2014-09-19
    Sponsor Name:DIAKO Ev. Diakonie-Krankenhaus Bremen gGmbH
    Full Title: Risk-stratified Sequential Treatment of Post-transplant Lymphoproliferative Disease (PTLD) With 4 Courses of Rituximab SC Followed by 4 Courses of Rituximab SC, 4 Courses of Rituximab SC Combined W...
    Medical condition: Previously untreated CD20-positive lymphoproliferative disorder (PTLD) following solid organ transplantation
    Disease: Version SOC Term Classification Code Term Level
    18.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10051358 Post transplant lymphoproliferative disorder PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-001473-25 Sponsor Protocol Number: CRAD001A2401 Start Date*: 2005-01-27
    Sponsor Name:Novartis Pharmaceuticals Corporation
    Full Title: A facilitated access program to provide Everolimus (RAD) for maintenance for patients completing therapy in RAD trials in solid organ transplantation.
    Medical condition: Solid Organ Transplant - maintenace phase
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-001294-24 Sponsor Protocol Number: ONEnTreg13 Start Date*: 2014-11-18
    Sponsor Name:Medizinischen Klinik mit Schwerpunkt Nephrologie und Internistische Intensivmedizin/Charité - Universitätsmedizin Berlin
    Full Title: The ONE Study: A Unified Approach to Evaluating Cellular Immunotherapy in Solid Organ Transplantation – Natural regulatory T-cells (nTregs) Trial.
    Medical condition: Kidney allograft rejection following living-donor renal transplantation.
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004865 10050436 Prophylaxis against renal transplant rejection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-004301-24 Sponsor Protocol Number: ONErgt11 Start Date*: 2012-01-05
    Sponsor Name:Free State of Bavaria, represented by the University of Regensburg, represented by Prof. Edward K. Geissler
    Full Title: The ONE Study: A Unified Approach to Evaluating Cellular Immunotherapy in Solid Organ Transplantation – Reference Group Trial
    Medical condition: Kidney allograft rejection following living-donor renal transplantation.
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004863 10051366 Kidney graft dysfunction LLT
    14.1 100000004870 10049581 Graft rejection episode LLT
    14.1 100000004865 10050436 Prophylaxis against renal transplant rejection LLT
    14.1 100000004863 10069030 Graft failure LLT
    14.1 100000004870 10038297 Rejection acute renal LLT
    14.1 100000004870 10021510 Immunosuppression NOS LLT
    14.1 100000004863 10038299 Rejection chronic renal LLT
    14.1 100000004870 10066543 Acute allograft rejection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) FR (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-000690-23 Sponsor Protocol Number: ADVL0612;NCI-07-C-0220 Start Date*: 2012-02-29
    Sponsor Name:National Institution of Health (NCI)
    Full Title: A Phase I Study of Sunitinib (SU11248), an Oral Multi-Targeted Tyrosine Kinase Inhibitor, in Children with Refractory Solid Tumors
    Medical condition: Paediatric solid tumours
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10065252 Solid tumor LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2011-006002-27 Sponsor Protocol Number: CHUBX2011/18 Start Date*: 2012-07-31
    Sponsor Name:CHU de Bordeaux
    Full Title: Multicentre trial evaluating the immunogenicity of HPV vaccination in girls on immunosuppressive therapy.
    Medical condition: Infection by HPV 6, 11, 16, 18
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-000999-15 Sponsor Protocol Number: ONEmreg12 Start Date*: 2014-02-10
    Sponsor Name:University Hospital Regensburg
    Full Title: The ONE Study: A Unified Approach to Evaluating Cellular Immunotherapy in Solid Organ Transplantation - M reg Trial
    Medical condition: Kidney allograft rejection following living-donor renal transplantation.
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004863 10051366 Kidney graft dysfunction LLT
    17.0 100000004870 10049581 Graft rejection episode LLT
    17.0 100000004863 10069030 Graft failure LLT
    17.0 100000004865 10050436 Prophylaxis against renal transplant rejection LLT
    17.0 100000004870 10038297 Rejection acute renal LLT
    17.0 100000004870 10021510 Immunosuppression NOS LLT
    17.0 100000004863 10038299 Rejection chronic renal LLT
    17.0 100000004870 10066543 Acute allograft rejection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-003048-21 Sponsor Protocol Number: Uni-Köln-1667 Start Date*: 2014-03-10
    Sponsor Name:University of Cologne
    Full Title: CONTROLING INTESTINAL COLONIZATION OF HIGH-RISK PATIENTS WITH EXTENDED- SPECTRUM BETALACTAMASE PRODUCING ENTEROBACTERIACEAE (ESBL-E) – A RANDOMIZED TRIAL (CLEAR)
    Medical condition: Immunocompromised patients at high risk of bloodstream infections with colonizing bacteria.
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004864 10066481 Hematological malignancy LLT
    16.1 100000004865 10067862 Allogeneic stem cell transplantation LLT
    16.1 100000004870 10054990 Immunodeficiency secondary to organ transplantation LLT
    16.1 100000004870 10021458 Immunodeficiency secondary to transplantation chemotherapy LLT
    16.1 100000004870 10021452 Immunodeficiency secondary to chemotherapy (excl corticosteroids) LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-024247-32 Sponsor Protocol Number: 1263-203 Start Date*: 2012-03-09
    Sponsor Name:VIROPHARMA INCORPORATED
    Full Title: A PHASE 2, RANDOMIZED, DOSE-RANGING STUDY TO ASSESS THE SAFETY AND ANTI-CYTOMEGALOVIRUS (CMV) ACTIVITY OF MARIBAVIR VERSUS VALGANCICLOVIR FOR TREATMENT OF CMV INFECTIONS IN TRANSPLANT RECIPIENTS WH...
    Medical condition: CMV INFECTIONS IN TRANSPLANT RECIPIENTS
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004862 10021819 Infection in marrow transplant recipients LLT
    14.1 100000004862 10021829 Infection in solid organ transplant recipients LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) DE (Completed) FR (Completed) AT (Completed) ES (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-022871-78 Sponsor Protocol Number: 201009H1N1MHH Start Date*: 2010-11-10
    Sponsor Name:Medizinische Hochschule Hannover
    Full Title: A Phase II Study to Evaluate the Immunogenicity, Safety and Tolerability of a Seasonal Influenza Vaccine including H1N1 in Immunocompromised Adults Who Have Undergone Solid Organ Transplantation or...
    Medical condition: Vaccination for seasonal influenza including H1N1 of immunocompromised adults who have undergone solid organ or bone marrow transplantation and of healthy adults
    Disease: Version SOC Term Classification Code Term Level
    12.1 10022000 Influenza LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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