Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Sternotomy

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    38 result(s) found for: Sternotomy. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2016-002606-39 Sponsor Protocol Number: 20162020 Start Date*: 2016-11-09
    Sponsor Name:Nemocnice Na Homolce
    Full Title: Resurgence in sternotomy fortified by vitamin D supplementation in cardiac surgery
    Medical condition: sternotomy healing
    Disease: Version SOC Term Classification Code Term Level
    19.0 10042613 - Surgical and medical procedures 10051501 Sternotomy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-002207-17 Sponsor Protocol Number: D-PLEX-302 Start Date*: 2020-07-14
    Sponsor Name:PolyPid Ltd.
    Full Title: A Phase III, Prospective, Multinational, Multicenter, Randomized, Parallel Controlled, Two arms, Single Blind, Study to Assess the Efficacy and Safety of D-PLEX Administered Concomitantly with the ...
    Medical condition: Prevention of Post-Cardiac Surgery Sternal Infections
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10078408 Surgical site infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-004738-25 Sponsor Protocol Number: CHUBX 2007/26 Start Date*: 2008-09-03
    Sponsor Name:CHU de Bordeaux
    Full Title: Etude des effets d’une infiltration continue péristernale de ropivacaïne sur l’hypersensibilité à la douleur consécutive à une sternotomie en chirurgie cardiaque
    Medical condition: Chirurgie cardiaque avec sternotomie médiane
    Disease: Version SOC Term Classification Code Term Level
    9.1 10051501 Sternotomy LLT
    Population Age: Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-024462-21 Sponsor Protocol Number: Reda 007583 Start Date*: 2011-04-26
    Sponsor Name:Research and Development, Barts and The London NHS Trust
    Full Title: Prospective, double-blinded, randomised, placebo controlled trial of pre-emptive analgesia to prevent pain following sternotomy for cardiac surgery.
    Medical condition: Chronic pain in the chest incision site (sternotomy) after cardiac surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-001170-33 Sponsor Protocol Number: 48656 Start Date*: 2015-01-29
    Sponsor Name:St. Antonius Hospital
    Full Title: Local Gentamicin in Redon treated Post-sternotomy Mediastinitis
    Medical condition: Post-sternotomy mediastinitis
    Disease: Version SOC Term Classification Code Term Level
    17.1 10021881 - Infections and infestations 10027082 Mediastinitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-004465-32 Sponsor Protocol Number: 2011/386 Start Date*: 2011-12-12
    Sponsor Name:Dept. of Cardiothoracic & Vascular Surgery, Aarhus University Hospital, Skejby
    Full Title: Can post-operative treatment with parathyroid hormone enhance bone healing and quality of newly formed bone after sternotomy in cardiac surgery patients?
    Medical condition: Sternotomy
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10051332 Surgical procedure LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-004307-20 Sponsor Protocol Number: Start Date*: 2012-02-09
    Sponsor Name:Reino Pöyhiä
    Full Title: Comparison of periosteal and subcutaneous infusions of articaine and bupivacaine in treatment of acute pain after sternotomy
    Medical condition: Patients undergoing elective open aortic or mitral valve, atrial septal defect or myxoma surgery
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10048935 Open heart surgery LLT
    14.1 10022117 - Injury, poisoning and procedural complications 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-002842-35 Sponsor Protocol Number: 2018/07 Start Date*: 2018-11-07
    Sponsor Name:CMC Ambroise Paré
    Full Title: Interest of parasternal block to prevent hypertensive and tachycardia episodes during sternotomy in patients undergoing coronary artery bypass graft
    Medical condition: coronary artery bypass graft
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10038286 Regional nerve block LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2021-005886-41 Sponsor Protocol Number: AUH-PAIN-01 Start Date*: 2022-06-29
    Sponsor Name:Aarhus University Hospital
    Full Title: Efficacy of Perioperative Long-acting Anesthesia by Local Infiltration Following Median Sternotomy - The PAIN Trial
    Medical condition: Acute postoperative pain after coronary bypass grafting surgery.
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-005169-33 Sponsor Protocol Number: CLEAN2 Start Date*: 2018-02-23
    Sponsor Name:CHU DE POITIERS
    Full Title: An open label, multicenter, randomized trial of 2% chlorhexidine-70% isopropanol vs 5% povidone iodine-69% ethanol for skin antisepsis in reducing surgical-site infection after cardiac surgery
    Medical condition: surgery of the heart (valve, coronary or combined surgery) or of the aorta via a median sternotomy
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10048935 Open heart surgery LLT
    20.0 100000004865 10049052 Aortic surgery NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-018301-11 Sponsor Protocol Number: 29421073 Start Date*: Information not available in EudraCT
    Sponsor Name:Centre chirurgical Marie Lannelongue
    Full Title: STUDY OF TRANAXAMIC ACID DOSAGE IN PEDIATRIC CARDIAC SURGERY
    Medical condition: DOSAGE OF ACID TRANEXAMIC ACID IN BLOOD SAMPLES DURING PAEDIATRIC CARDIAC SURGERY
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-005701-20 Sponsor Protocol Number: ANST2015_1 Start Date*: 2015-05-20
    Sponsor Name:Leiden University Medical Center
    Full Title: Shifting pain modulation towards anti-nociceptivity: Mechanism-specific pharmacological prevention of post sternotomy pain: the MASTER study
    Medical condition: chronic pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-004672-35 Sponsor Protocol Number: PACS2019 Start Date*: 2020-01-10
    Sponsor Name:Institution for Clinical Science, Karolinska Institutet
    Full Title: Open heart surgery – does it have to hurt that much? PACS – Parasternal After Cardiac Surgery. A prospective randomised study to assess the analgesic effect of a continuous bilateral parasternal bl...
    Medical condition: The analgesic effect of continuous bilateral parasternal infusion of local anaesthetic after open cardiac surgery.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-012372-27 Sponsor Protocol Number: 200901 Start Date*: 2009-09-17
    Sponsor Name:LUMC
    Full Title: The Sevoflurane study, understanding the effects of Sevoflurane to improve safety and outcome of cardiac surgery
    Medical condition: myocardial ischemia reperfusion injury during cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10017501 Functional disturbances following cardiac surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-004178-23 Sponsor Protocol Number: T39/2021 Start Date*: 2021-04-14
    Sponsor Name:Turku University Hospital
    Full Title: Ultrasound Guided Repeated Bilateral Transversus Thoracis Muscle Plane Block (TTP) via catheter and postoperative pain in Cardiac Surgery
    Medical condition: cardiac disease necessitating surgery with sternotomy
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10046972 Valvular heart disease NOS LLT
    20.0 100000004849 10055218 Ischemic heart disease LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-024201-12 Sponsor Protocol Number: Start Date*: 2011-08-03
    Sponsor Name:Med. Uni. Wien, Universitätsklinik für Anästhesie, Allgemeine Intensivmedizin und Schmerztherapie
    Full Title: Klinische Pilotstudie Zum Prospektiven Vergleich der Analgetischen Wirksamkeit Eines Oralen Und Eines Invasiven Opiat-Regimes Nach Herzchirurgischen Operationen
    Medical condition: efficacy, compatibility and potential side effects of oral Targin® in the treatment of postoperative pain after major cardiac surgery. Therefore, we compare the standardized postoperative pain con...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2017-003278-15 Sponsor Protocol Number: AGO/2017/005 Start Date*: 2017-12-14
    Sponsor Name:Ghent University Hospital
    Full Title: Hyperalgesia, Persistent Pain, and Fentanyl Dosing in On-Pump Coronary Artery Bypass Grafting
    Medical condition: Secondary wound hyperalgesia Persistent Pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-000201-23 Sponsor Protocol Number: reflect01 Start Date*: 2013-08-30
    Sponsor Name:St. Antonius Ziekenhuis
    Full Title: A randomised clinical trial evaluating the effect of remifentanil vs fentanyl during cardiac surgery on the incidence of chronic thoracic pain.
    Medical condition: chronic thoracic pain after cardiac surgery via sternotomy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-002508-29 Sponsor Protocol Number: CEFTAROPROPH Start Date*: 2018-02-09
    Sponsor Name:MedUni Vienna, Dept of Anesthesia, Critical Care, Div. of Cardiothoracic and Vascular Anesthesia
    Full Title: Ceftaroline (Zinforo®) as antibiotic prophylaxis for CABG-surgery: An In-vivo microdialysis study
    Medical condition: Antibiotic prophylaxis for CABG surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10036894 Prophylactic antibiotic therapy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-000505-39 Sponsor Protocol Number: CHUBX2014/13 Start Date*: 2015-03-19
    Sponsor Name:CHU de Bordeaux
    Full Title: The role of dexchlorpheniramine (Polaramine®) to prevent hemodynamic instability after separation from cardiopulmonary bypass during cardiac surgery.
    Medical condition: vasoplegic syndrome
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004863 10067654 Vasoplegic syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    1  2  Next»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Sun May 19 20:24:42 CEST 2024 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA