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Clinical trials for Systolic

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    1,633 result(s) found for: Systolic. Displaying page 1 of 82.
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    EudraCT Number: 2022-001283-10 Sponsor Protocol Number: NL80929.091.22 Start Date*: 2022-06-28
    Sponsor Name:Radboud University Medical Center
    Full Title: The effects of medication induced blood pressure reduction on cerebral hemodynamics in hypertensive frail elderly
    Medical condition: Hypertension
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-004534-24 Sponsor Protocol Number: 2007CV09 Start Date*: 2008-11-18
    Sponsor Name:University of Dundee
    Full Title: Can high-dose vitamin D supplementation reduce blood pressure and markers of cardiovascular risk in older people with isolated systolic hypertension?
    Medical condition: Isolated systolic hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050591 Isolated systolic hypertension LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-001227-40 Sponsor Protocol Number: SMR-2271(SER100-001) Start Date*: 2013-09-23
    Sponsor Name:Serodus ASA
    Full Title: A randomized, double-blind, placebo-controlled, cross-over, multi-center study assessing the safety, tolerability and efficacy of SER100 10 mg s.c. twice daily for 2 days in patients with Isolated ...
    Medical condition: Isolated Systolic Hypertension
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004866 10050591 Isolated systolic hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed) FI (Prematurely Ended) HU (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-011296-80 Sponsor Protocol Number: CSPP100AFR01 Start Date*: 2009-06-10
    Sponsor Name:Novartis Pharma S.A.S
    Full Title: Efficacy of Rasilez® (Aliskiren) compared to ramipril in the treatment of moderate systolic hypertensive patients
    Medical condition: Hypertension artérielle systolique
    Disease: Version SOC Term Classification Code Term Level
    9.1 10042957 Systolic hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2010-023104-28 Sponsor Protocol Number: MEIN/10/Neb+HCTZ-Hyp/001 Start Date*: 2011-10-20
    Sponsor Name:Menarini International Operations Luxembourg S.A.
    Full Title: A multicentre randomised, double blind, active controlled, parallel group comparison of Nebivolol plus HCTZ and Irbesartan plus HCTZ in the treatment of isolated systolic hypertension in elderly pa...
    Medical condition: Isolated Systolic Hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.0 10047065 - Vascular disorders 10050591 Isolated systolic hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-002051-15 Sponsor Protocol Number: KM-HYPO Start Date*: 2014-11-04
    Sponsor Name:Innsbruck Medical University, Department of Radiology, Section of Microinvasive Therapy
    Full Title: Systemic hypotension following intravenous administration of contrast medium during computed tomography.
    Medical condition: Primary goal of this study is to quantify changes in systolic and diastolic blood pressure, heart rate and pO2 before and after i.v. administration of either IOCM or LOCM. In particular the occurre...
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2018-003905-25 Sponsor Protocol Number: HAC2018-001 Start Date*: 2019-06-27
    Sponsor Name:H.A.C. Pharma
    Full Title: Evaluation of efficacy and tolerance of fludrocortisone (Flucortac) in the treatment of neurogenic orthostatic hypotension
    Medical condition: Neurogenic Orthostatic Hypotension (NOH)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10047065 - Vascular disorders 10031127 Orthostatic hypotension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-000068-40 Sponsor Protocol Number: FAIR-HF2 Start Date*: 2017-01-27
    Sponsor Name:University Medical Center Hamburg-Eppendorf
    Full Title: Intravenous iron in patients with systolic heart failure and iron deficiency to improve morbidity & mortality. Ferric carboxymaltose Assessment of morbidity and mortality in patients with IRon de...
    Medical condition: Systolic heart failure associated with iron deficiency
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10074631 Systolic heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) HU (Completed) PT (Completed) SI (Completed) PL (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004862-33 Sponsor Protocol Number: BCBe/04/Neb-Gla/081 Start Date*: 2006-05-23
    Sponsor Name:Berlin-Chemie Menarini
    Full Title: INFLUENCE OF NEBIVOLOL ON OCULAR PERFUSION IN PATIENTS WITH ARTERIAL HYPERTENSION AND GLAUCOMA A mono-center, active-substance controlled, randomized, double-blind, prospective phase IV parallel-g...
    Medical condition: Arterial hypertension and glaucoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-003075-12 Sponsor Protocol Number: 290478 Start Date*: Information not available in EudraCT
    Sponsor Name:Department Of Paediatric Cardiology
    Full Title: Effect of carvedilol on left ventricular systolic and diastolic function and the neurohormonal axis in patients with Duchenne muscular dystrophy and left ventricular dysfunction.
    Medical condition: Duchenne muscular dystrophy is an X-linked inherited disorder which primarily affects skeletal muscle through a mutation in dystrophin which maps to the long arm of the X chromosome (Xp21). Patient...
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-005893-93 Sponsor Protocol Number: 00909043 Start Date*: 2021-09-21
    Sponsor Name:Uniwersytet Medyczny w Białymstoku
    Full Title: A randomized, double-blind, placebo-controlled study evaluating levosimendan re-infusions in patients with severe heart failure with reduced left ventricular ejection fraction.
    Medical condition: Ambulatory Heart Failure Patients
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10074631 Systolic heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-001005-27 Sponsor Protocol Number: 1818 Start Date*: 2011-05-02
    Sponsor Name:Department of Anaesthesiology, University Hospital of Skejby
    Full Title: The effect of dobtutamin on postoperative systolic deformation and diastolic function in patients with concentric hypertrophy of the left ventricle
    Medical condition: Aortic stenosis Diastolic dysfunction
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10002907 Aortic stenosis & incompetence LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-006861-18 Sponsor Protocol Number: 20061212 Start Date*: 2007-03-26
    Sponsor Name:Department of Cardiology
    Full Title: Comparison between beta-adrenergic blockers and angiotensin II receptor antagonists for the treatment of late hypertension in patients with repaired aortic coarctation
    Medical condition: Aortic coarctation and late hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-018125-70 Sponsor Protocol Number: ENM-EA-016 Start Date*: 2011-04-06
    Sponsor Name:Medizinische Universität Graz
    Full Title: Styrian Vitamin D Hypertension Trial: A randomized, double-blind, placebo controlled trial to study the effects of vitamin D supplementation on systolic blood pressure in vitamin D deficient hypert...
    Medical condition: Patients with arterial hypertension and vitamin D deficiency
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2011-005522-22 Sponsor Protocol Number: Rifa-BP Start Date*: 2012-01-23
    Sponsor Name:Oulu University Hospital, Department of Internal Medicine
    Full Title: The effects of PXR activation on blood pressure regulation
    Medical condition: Healthy volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2007-001538-15 Sponsor Protocol Number: 6034 Start Date*: 2007-06-12
    Sponsor Name:Sangart Inc
    Full Title: A randomized, single-blind, controlled Phase II pilot study of Hemospan® compared with colloid (Voluven®) to evaluate vascular resistance and blood flow in the forearm, and to assess local skin blo...
    Medical condition: chronic critical limb ischemia (CCLI)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-004659-36 Sponsor Protocol Number: SP-OLM-03-05 OLMETREAT Start Date*: 2006-04-05
    Sponsor Name:Daiichi SankyoGmbH
    Full Title: Treat-to-target study of olmesartan medoxomil and an add-on treatment algorithm consisting of hydrochlorothiazide and amlodipine besylate in patients with mild to moderate hypertension
    Medical condition: Mild to moderate hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) GB (Completed) PT (Completed) AT (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2016-004236-38 Sponsor Protocol Number: 12250 Start Date*: 2017-01-24
    Sponsor Name:University of Oxford
    Full Title: OPtimising Treatment for MIld Systolic hypertension in the Elderly: a randomised controlled trial
    Medical condition: Hypertension
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2005-000333-38 Sponsor Protocol Number: Hcy2005 Start Date*: 2005-05-25
    Sponsor Name:Organisation name was not entered
    Full Title: A randomized placebo-controlled trial to investigate blood pressure lowering effects of folic acid in patients with borderline hypertension.
    Medical condition: Patients with hyperhomocysteinemia and high-normal blood pressure, otherwise healthy
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-003387-22 Sponsor Protocol Number: Start Date*: 2007-10-07
    Sponsor Name:Pharma 2100 ApS
    Full Title: Et velkendt lægemiddels helende effekt på iskæmiske sår: et randomiseret dobbelt-blindt placebokontrolleret pilotforsøg
    Medical condition: Out-patients with ischemic (arterial) leg ulcers (systolic toe pressure: < 40 mm Hg).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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