Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Transepidermal water loss

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    36 result(s) found for: Transepidermal water loss. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2015-002699-26 Sponsor Protocol Number: PREFECT Start Date*: 2015-10-08
    Sponsor Name:GWT-TUD GmbH
    Full Title: Pilot study of tolerability and effectivity following application of two combination topical acne products clindamycin 1% and 0.025% tretinoin gel (Acnatac® Gel), adapalen 0,1% and benzoyl peroxide...
    Medical condition: acne vulgaris
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-002284-14 Sponsor Protocol Number: 1528 Start Date*: 2012-03-14
    Sponsor Name:Schur Pharmazeutika GmbH & Co. KG
    Full Title: Subacute local tolerance of an ointment containing 0.5% neomycin sulfate (Myacyne Salbe)
    Medical condition: Sensitive skin areas under non-occlusive and occlusive conditions
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004824-11 Sponsor Protocol Number: ELBE-2005 Start Date*: 2005-04-15
    Sponsor Name:Universitätshautklinik Kiel
    Full Title: Role for pimecrolimus in restoring skin barrier function and normalizing epidermal lipid content and differentiation in atopic epidermis: a randomized, intra-patient, double-blind (right/left arm) ...
    Medical condition: Atopic Dermatitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-002081-12 Sponsor Protocol Number: AHV-18-A Start Date*: 2019-12-19
    Sponsor Name:Amryt Research Ltd.
    Full Title: An exploratory randomized, intra-individual controlled trial of the cutaneous healing properties of Petrolatum versus the vehicle for Oleogel-S10 versus no treatment when applied topically to me...
    Medical condition: Not applicable, as healthy volunteers will be recruited, who will receive mechanically induced partial thickness wounds.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-016571-30 Sponsor Protocol Number: DERL-02 Start Date*: 2010-02-01
    Sponsor Name:Dermal Laboratories Ltd
    Full Title: A study to determine the effects on stratum corneum of a clinical hand cleansing protocol comparing two antiseptic hand washes, using non-invasive instrumental methods in human volunteers.
    Medical condition: No medical condition is to be investigated, as such. We are looking to avoid occupational hand dermatitis in healthcare professionals, simulated using a repeat hand wash cleansing protocol in heal...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-000552-27 Sponsor Protocol Number: ACO2008-CT-01 Start Date*: 2008-06-11
    Sponsor Name:ACO HUD NORDIC AB
    Full Title: Effect of moisturizing creams on skin barrier function and prevention of Malassezia recurrence in patients with atopic eczema
    Medical condition: Dry skin barrier disorders such as atopic eczema and ichtyosis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-000333-22 Sponsor Protocol Number: DERL-01 Start Date*: 2008-04-30
    Sponsor Name:Dermal Laboratories Ltd
    Full Title: A study to compare the effects on stratum corneum of two medical hand wash formulations, using non-invasive instrumental methods in human volunteers.
    Medical condition: The study is a healthy volunteer study.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-005649-12 Sponsor Protocol Number: SUCPAT1_CTR0026 Start Date*: 2006-12-20
    Sponsor Name:Regent Medical
    Full Title: A 96 hour (4-application) patch test and TEWL assessment in healthy volunteers to investigate the comparative skin irritation potential of six antiseptics and two controls following cutaneous patch...
    Medical condition: This trial will be carried out on healthy volunteers. Patches containing 0.2mls of each test product will be used. Each volunteer will have a single patch per product and the patches will be remov...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2013-005619-28 Sponsor Protocol Number: 2012.786 Start Date*: 2014-07-23
    Sponsor Name:Hospices Civils de Lyon
    Full Title: Influence of lipid emulsions for parenteral nutrition on the fonctional state of cutaneous barrier
    Medical condition: patients avec une insuffisance intestinale chronique sévère recevant une nutrition parentérale au long cours
    Disease: Version SOC Term Classification Code Term Level
    18.0 10042613 - Surgical and medical procedures 10051284 Parenteral nutrition PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-023543-15 Sponsor Protocol Number: CL09002 Start Date*: 2011-01-24
    Sponsor Name:BioCis Pharma Oy
    Full Title: Double-blind, placebo-controlled, multi-centre Phase II study to investigate dose response, safety, tolerability and efficacy of topical twice daily doses of 2.5% and 5% cis-urocanic acid in compar...
    Medical condition: Chronic moderate or severe atopic dermatitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-008332-90 Sponsor Protocol Number: CL08004 Start Date*: 2009-02-10
    Sponsor Name:BioCis Pharma Oy
    Full Title: Double-blind, vehicle-controlled, single centre Phase I/IIa study with topical twice daily doses of 5% cis-urocanic acid to investigate pharmacokinetics, safety, tolerability, and efficacy for up t...
    Medical condition: Mild to moderate plaque psoriasis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-003106-99 Sponsor Protocol Number: ELBE II-2007 Start Date*: 2007-10-04
    Sponsor Name:University of Kiel, Department of Dermatology
    Full Title: Pimecrolimus and Epidermal Barrier Function: Role for pimecrolimus in restoring skin barrier function and normalizing epidermal lipid content and differentiation in atopic epidermis: a randomized, ...
    Medical condition: Investigative study of pathogenesis/treatment of calcineurin inhibitor vs. corticosteroid confirmatory study to prior study: Pimecrolimus and Epidermal Barrier Function, Protocol No. ELBE-2005, Eud...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-006208-21 Sponsor Protocol Number: ELKE-2006 Start Date*: 2006-10-23
    Sponsor Name:Department of Dermatology, University of Kiel
    Full Title: Clinical Efficacy of Pimecrolimus Cream in Seborrheic Dermatitis. Efficacy of pimecrolimus in normalizing clinical symptoms, explorative study of barrier function, hydration, lipid content and diff...
    Medical condition: Efficacy of pimecrolimus in normalizing clinical symptoms, explorative study of barrier function, hydration, lipid content and differentiation in seborrheic dermatitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-018624-20 Sponsor Protocol Number: OPM-CIC-G-H-0902 Start Date*: 2010-05-19
    Sponsor Name:University Medical Center Freiburg
    Full Title: Tolerance of virucidal alcohol-based hand rubs - healthy volunteer trial
    Medical condition: Only healthy volunteers are included in this trial. Alcohol-based hand rubs are licensed drugs in Germany. They are indicated to perform hand disinfection by health care workers and are used within...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-005075-10 Sponsor Protocol Number: CL08002 Start Date*: 2008-10-01
    Sponsor Name:BioCis Pharma Oy
    Full Title: Double-blind, vehicle-controlled, two-phase, single centre Phase I/IIa study with topical twice daily doses of 5% cis-urocanic acid to investigate pharmacokinetics, safety, tolerability and efficac...
    Medical condition: Chronic mild to moderate atopic dermatitis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-004370-96 Sponsor Protocol Number: LG-TCS-AD Start Date*: 2019-02-15
    Sponsor Name:Jacob Pontoppidan Thyssen
    Full Title: The effects of topical corticosteroid use on insulin sensitivity and bone turnover
    Medical condition: Atopic dermatitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004858 10003639 Atopic dermatitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2019-001220-35 Sponsor Protocol Number: RC31-19-0045 Start Date*: 2019-10-08
    Sponsor Name:CHU de Toulouse
    Full Title: A randomized double-blinded pilot study of the efficacy and safety of dupilumab versus placebo in patients with Netherton syndrome
    Medical condition: Netherton syndrome
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10062909 Netherton's syndrome PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-004278-32 Sponsor Protocol Number: 14031972 Start Date*: 2020-12-04
    Sponsor Name:Falck clinic
    Full Title: Satisfaction study of split doses botulinum toxin with double frequency
    Medical condition: Wrinkles, fine lines
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2021-003210-39 Sponsor Protocol Number: SXR001 Start Date*: 2021-11-23
    Sponsor Name:Sixera Pharma
    Full Title: A phase I/II, multicenter, randomized, double-blind, placebo within-patient controlled, first-time-in-man (FTIM) Proof of Concept (PoC) study to evaluate the safety and efficacy of topically applie...
    Medical condition: Netherton-syndrome
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10062909 Netherton's syndrome PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: FI (Completed) SE (Trial now transitioned) AT (Trial now transitioned) DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-020841-29 Sponsor Protocol Number: ADAPT Start Date*: 2011-07-07
    Sponsor Name:King`s College London [...]
    1. King`s College London
    2. Guy`s & St Thomas` NHS Foundation Trust
    Full Title: The role of anti-IgE (omalizumab) in the management of severe recalcitrant paediatric atopic eczema
    Medical condition: Severe eczema in children
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004858 10003641 Atopic eczema LLT
    19.0 100000004858 10014189 Eczema allergic atopic LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    1  2  Next»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Sun May 11 23:44:03 CEST 2025 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA