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Clinical trials for Trauma

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    393 result(s) found for: Trauma. Displaying page 1 of 20.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2014-003978-16 Sponsor Protocol Number: PRooF-iTH Start Date*: 2015-01-22
    Sponsor Name:Section for Transfusion Medicine, Capitol Region Blood Bank
    Full Title: Pilot Randomized trial of Fibrinogen in Trauma Haemorrhage (PRooF-iTH).
    Medical condition: Trauma patients with ongoing haemorrhage
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004866 10005103 Bleeding LLT
    17.1 100000004863 10044461 Trauma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2017-000338-70 Sponsor Protocol Number: MR311-3502 Start Date*: 2017-06-19
    Sponsor Name:Mundipharma Pharmaceuticals, S.L.
    Full Title: A phase IIIb open randomized clinical trial to compare pain relief between methoxyflurane and standard of care for treating patients with trauma pain in Spanish emergency units.
    Medical condition: Trauma Pain
    Disease: Version SOC Term Classification Code Term Level
    19.1 10022117 - Injury, poisoning and procedural complications 10065016 Post-traumatic pain PT
    19.1 10022117 - Injury, poisoning and procedural complications 10044461 Trauma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-000875-28 Sponsor Protocol Number: Start Date*: 2016-08-19
    Sponsor Name:NHS Blood & Transplant
    Full Title: A multi-centre, randomised, double blind, placebo-controlled trial evaluating the effects of early administration of fibrinogen concentrate in adults with major traumatic haemorrhage. E-FIT 1 Study
    Medical condition: Trauma patients whereby the local major haemorrhage protocol has been activated
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004863 10044461 Trauma LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-004250-15 Sponsor Protocol Number: Start Date*: 2018-06-08
    Sponsor Name:University Hospitals Birmingham
    Full Title: A prospective, phase II, single centre, cross-sectional, randomised trial investigating Dehydroepiandrosterone and it's Pharmacokinetics in Trauma
    Medical condition: DHEA depletion in trauma and hip fracture patients.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022891 - Investigations 10056629 Dehydroepiandrosterone decreased PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2011-004177-83 Sponsor Protocol Number: 37202 Start Date*: 2011-11-14
    Sponsor Name:Academic Medical Center
    Full Title: Boosting the oxytocin system in acute trauma: The effectiveness of intranasal oxytocin treatments and stimulation of social support on preventing trauma related psychopathology
    Medical condition: Posttraumatic Stress Disorder (PTSD) according to criteria in the DSM-IV
    Disease: Version SOC Term Classification Code Term Level
    14.0 10037175 - Psychiatric disorders 10036316 Post-traumatic stress disorder PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-002097-38 Sponsor Protocol Number: ABR62020 Start Date*: 2018-06-05
    Sponsor Name:University Medical Centre Utrecht
    Full Title: SAMe as an epigenetic treatment of depression in people with childhood trauma, a double blind placebo-controlled trial
    Medical condition: Depressive episode in people with childhood trauma
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-004469-28 Sponsor Protocol Number: MR311-4501 Start Date*: 2018-03-01
    Sponsor Name:MUNDIPHARMA
    Full Title: Multicentre, randomised, double-blind study assessing the efficacy and safety of Penthrox® combined with a standard analgesia (SoC) in comparison to a placebo combined with a standard analgesia (So...
    Medical condition: Emergency relief of moderate to severe pain associated with trauma in conscious adult patients
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004863 10044461 Trauma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-002255-10 Sponsor Protocol Number: IRMINEpilot Start Date*: 2016-06-30
    Sponsor Name:Abertawe Bro Morgannwg University Health Board
    Full Title: INFLAMMATORY RESPONSE IN MAJOR INJURY & RECOMBINANT HUMAN ERYTHROPOIETIN (IRMINE) - A PILOT STUDY
    Medical condition: Post-trauma multiple organ failure: a manifestation of the systemic inflammatory/immune response to major injuries.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004870 10021459 Immunodeficiency secondary to trauma LLT
    20.0 100000004867 10028237 Multiple organ failure LLT
    20.0 10022117 - Injury, poisoning and procedural complications 10044461 Trauma LLT
    20.0 10022117 - Injury, poisoning and procedural complications 10044541 Traumatic shock PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-000936-24 Sponsor Protocol Number: SHINE-TRAUMA Start Date*: 2019-05-02
    Sponsor Name:Section for Transfusion Medicine, Capital Region Blood Bank, Copenhagen University Hospital
    Full Title: Efficacy and safety of 72-hour infusion of Prostacyclin (1 ng/kg/min) in trauma patients with haemorrhagic shock induced endotheliopathy – a multicentre randomized, placebo-controlled, blinded, inv...
    Medical condition: Shock-induced endotheliopathy in trauma patients
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10044528 Traumatic injury LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) NO (Completed)
    Trial results: View results
    EudraCT Number: 2013-002545-10 Sponsor Protocol Number: OSU6162Open1309 Start Date*: 2014-01-08
    Sponsor Name:A. Carlsson Research AB
    Full Title: An open safety study with the monoaminergic stabilizer (-)-OSU6162 in patients with mental fatigue and related vitality and wakefulness disturbances associated with neurologiacal disorders, e g P...
    Medical condition: Parkinsons disease Huntingtons disease Multiple scleros Brain trauma Stroke Myalgic encephalomyelitis Narcolepsy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-000654-22 Sponsor Protocol Number: 6998 Start Date*: 2018-11-09
    Sponsor Name:Hôpitaux Universitaires de Strasbourg
    Full Title: A Prospective, Randomized Multicenter, Double Blind Clinical Trial Comparing Inhaled Dornase Alfa and Its Placebo to Reduce the Incidence of Moderate to Severe ARDS in Ventilated Trauma Patients in...
    Medical condition: Multiple Trauma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2022-002944-40 Sponsor Protocol Number: CHUB-Methoxyflurane Start Date*: 2023-02-14
    Sponsor Name:CHU Brugmann
    Full Title: Prospective monocentric randomized study: use of Methoxyflurane via a mouth-nose mask versus inhaler in the management of pain following limb trauma
    Medical condition: Acute limb trauma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2011-005235-22 Sponsor Protocol Number: ANZIC-RC/RB002 Start Date*: 2012-01-18
    Sponsor Name:Monash University
    Full Title: A randomised, placebo-controlled trial of erythropoietin in ICU patients with traumatic brain injury: Erythropoietin in Traumatic Brain Injury
    Medical condition: Traumatic brain injury
    Disease: Version SOC Term Classification Code Term Level
    14.0 10022117 - Injury, poisoning and procedural complications 10056380 Traumatic brain damage LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed) FR (Ongoing) DE (Ongoing) IE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002955-14 Sponsor Protocol Number: ISRCTN86750102 Start Date*: 2008-07-28
    Sponsor Name:London School of Hygiene and Tropical Medicine [...]
    1. London School of Hygiene and Tropical Medicine
    2. World Health Organisation
    Full Title: A large randomised placebo controlled trial among trauma patients with or at risk of significant haemorrhage, of the effects of antifibrinolytic treatment on death and transfusion requirement
    Medical condition: Haemorrhage following Trauma
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) BE (Completed) SK (Completed) PT (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2015-000301-40 Sponsor Protocol Number: 009531 Start Date*: 2016-03-11
    Sponsor Name:Queen Mary University of London
    Full Title: A randomised, blinded, placebo-controlled Phase 2a study to evaluate the safety and efficacy of Artesunate treatment in severely injured trauma patients with traumatic haemorrhage.
    Medical condition: Organ Dysfunction and Failure in Traumatic Hemorrhage
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-000209-12 Sponsor Protocol Number: CHUBX 2007/32 Start Date*: 2009-02-25
    Sponsor Name:CHU de Bordeaux
    Full Title: Effet comparé sur le débit sanguin et le métabolisme cérébral de deux types de prise en charge des accès d'hypertension intracrânienne après traumatisme crânien sévère : mannitol vs sérum salé hype...
    Medical condition: Traumatisé crânien sévère Hypertension intracrânienne
    Disease: Version SOC Term Classification Code Term Level
    9.1 10022764 Intracranial hypertension LLT
    9.1 10019196 Head injury LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: View results
    EudraCT Number: 2012-003289-42 Sponsor Protocol Number: 41399 Start Date*: 2012-12-21
    Sponsor Name:Academic Medical Center Amsterdam
    Full Title: Randomized Controlled Trial Investigating the Efficacy and Safety of Nebulized Heparin versus Placebo in Burn Patients with Inhalation Trauma
    Medical condition: Burn-associated inhalation trauma requiring intubation and mechanical ventilation.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-000898-23 Sponsor Protocol Number: 2019/KEP/218 Start Date*: 2019-08-01
    Sponsor Name:London School of Hygiene and Tropical Medicine
    Full Title: Pharmacokinetics of intramuscular tranexamic acid in trauma patients: a clinical trial
    Medical condition: Traumatic haemorrhage
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022117 - Injury, poisoning and procedural complications 10053476 Traumatic haemorrhage PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-002210-71 Sponsor Protocol Number: 38RC15.154 Start Date*: 2015-07-01
    Sponsor Name:University Hospital Grenoble
    Full Title: Impact of dexmedetomidine on preventive noninvasive ventilation in thoracic trauma
    Medical condition: Thoracic trauma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-000925-60 Sponsor Protocol Number: R1/11 Start Date*: 2011-10-18
    Sponsor Name:Kungälv Hospital
    Full Title: Effect of treatment with methylphenidate on mental fatigue (“brain fatigue”) and pain on persons who have suffered a traumatic brain injury or whip lash injury – a pilot study.
    Medical condition: Mental fatigue after traumatic brain injury or whip-lash injury
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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