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Clinical trials for Tropical diseases

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    130 result(s) found for: Tropical diseases. Displaying page 1 of 7.
    1  2  3  4  5  6  7  Next»
    EudraCT Number: 2014-001836-12 Sponsor Protocol Number: ITMC0414 Start Date*: 2014-07-31
    Sponsor Name:Institute of Tropical Medicine
    Full Title: Boostability for rabies in last-minute travelers: One Day Rabies Pre-exposure Intradermal Vaccination followed by one day Postexposure Intradermal Vaccination
    Medical condition: Rabies is a viral infection that affects the central nervous system. It causes encephalitis which is almost invariably fatal. Preventive vaccination alone implies no complete protection, but simpli...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2011-001612-62 Sponsor Protocol Number: ITMC0211 Start Date*: 2011-09-06
    Sponsor Name:Institute of Tropical Medicine Antwerp
    Full Title: Simplifying the Rabies Pre-exposure Vaccination
    Medical condition: Rabies is a viral infection that affects the central nervous system. It causes encephalitis which is almost invariably fatal. Preventive vaccination alone implies no complete protection, but simpli...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2022-004143-27 Sponsor Protocol Number: STRONG-FIX Start Date*: 2023-09-14
    Sponsor Name:Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca (VHIR)
    Full Title: Randomized non-inferiority clinical trial to evaluate the efficacy of a single fixed dose of 18 mg ivermectin for the treatment of uncomplicated strongyloidiasis
    Medical condition: Strongyloidiasis is caused by a parasite that is globally distributed in tropical and sub-tropical areas. Most patients with strongyloidiasis are asymptomatic or have mild symptoms with gastrointes...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10042254 Strongyloidiasis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-003616-10 Sponsor Protocol Number: ITM202101 Start Date*: 2021-11-04
    Sponsor Name:Institute of Tropical Medicine
    Full Title: An open label randomized controlled trial comparing the effect of ceftriaxone plus azithromycin versus ceftriaxone for the treatment of Neisseria gonorrhoeae on the resistome
    Medical condition: Neisseria gonorrhoeae (Ng)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004862 10051970 Neisseria gonorrhoeae infection LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-000649-16 Sponsor Protocol Number: PRV-015-002b Start Date*: 2021-04-06
    Sponsor Name:Provention Bio, Inc.
    Full Title: A Phase 2b, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of PRV-015 in Adult Patients with Non-Responsive Celiac Disease as an Adjunct to a...
    Medical condition: Celiac Disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004856 10007864 Celiac disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-003660-31 Sponsor Protocol Number: ALV003-1221 Start Date*: 2013-11-27
    Sponsor Name:Alvine Pharmaceuticals, Inc.
    Full Title: A Phase 2b, Randomized, Double-Blind, PLacebo-Controlled Dose-Ranging Study of the Efficacy and Safety of ALV003 Treatment in Symptomatic Celiac Disease Patients Maintained on a Gluten-Free Diet
    Medical condition: Celiac Disease
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004856 10007864 Celiac disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) GB (Completed) IE (Completed) NO (Completed)
    Trial results: View results
    EudraCT Number: 2020-005438-14 Sponsor Protocol Number: TAK-062-2001 Start Date*: 2022-11-15
    Sponsor Name:TAKEDA
    Full Title: A Phase 2, Randomized, Double-blind, Placebo-Controlled, Dose-Ranging Study to Evaluate the Efficacy and Safety of TAK-062 for the Treatment of Active Celiac Disease in Subjects Attempting a Gluten...
    Medical condition: Active Celiac Disease in subjects attempting a Gluten-Free Diet
    Disease: Version SOC Term Classification Code Term Level
    20.0 10017947 - Gastrointestinal disorders 10009839 Coeliac disease PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) ES (Completed) Outside EU/EEA NL (Ongoing) BE (Completed) PL (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-004612-97 Sponsor Protocol Number: CEC-4/CEL Start Date*: 2021-08-12
    Sponsor Name:Dr. Falk Pharma GmbH
    Full Title: A phase IIb, double-blind, randomised, placebo-controlled trial to evaluate the efficacy and tolerability of ZED1227 in celiac disease subjects experiencing symptoms despite gluten-free diet
    Medical condition: Treatment of celiac disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 10017947 - Gastrointestinal disorders 10007864 Celiac disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) LT (Completed) DE (Completed) NO (Completed) EE (Completed) IE (Completed) AT (Completed) FR (Completed) IT (Completed) SE (Completed) ES (Completed) PL (Completed) BG (Completed) HR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-001417-21 Sponsor Protocol Number: ITM202004 Start Date*: 2020-04-12
    Sponsor Name:Institute of Tropical Medicine
    Full Title: An open label single center randomized controlled trial to evaluate the effect of hydroxychloroquine on viral shedding in mild COVID-19
    Medical condition: COVID-19
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10047438 Viral infectious disorders HLGT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-000141-31 Sponsor Protocol Number: ISRCTN30952488 Start Date*: 2016-08-30
    Sponsor Name:London School of Hygiene and Tropical Medicine
    Full Title: A SERIES OF RANDOMISED CONTROLLED N-of 1 TRIALS IN PATIENTS WHO HAVE DISCONTINUED OR WISH TO DISCONTINUE STATIN USE DUE TO MUSCLE-RELATED SYMPTOMS TO ASSESS IF ATORVASTATIN TREATMENT CAUSES MORE MU...
    Medical condition: myalgia
    Disease: Version SOC Term Classification Code Term Level
    19.0 10028395 - Musculoskeletal and connective tissue disorders 10028411 Myalgia PT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-003604-12 Sponsor Protocol Number: ITM201902 Start Date*: 2020-01-15
    Sponsor Name:Institute of Tropical Medicine
    Full Title: Evaluation of a chlorhexidine mouthwash for the eradication of asymptomatic pharyngeal Neisseria gonorrhoeae infection
    Medical condition: asymptomatic pharyngeal Neisseria gonorrhoeae (NG)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004862 10051970 Neisseria gonorrhoeae infection LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-003669-14 Sponsor Protocol Number: ISRCTN15088122 Start Date*: 2012-12-03
    Sponsor Name:London School Of Hygiene and Tropical Medicine
    Full Title: Tranexamic Acid for the treatment of significant traumatic brain injury: an international, randomised, double blind, placebo controlled trial.
    Medical condition: Traumatic Brain Injury
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022117 - Injury, poisoning and procedural complications 10060690 Traumatic brain injury LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) GB (Completed) IT (Completed) IE (Completed) SI (Completed)
    Trial results: View results
    EudraCT Number: 2005-000567-25 Sponsor Protocol Number: 100063 Start Date*: 2005-08-10
    Sponsor Name:NUMICO RESEARCH BV
    Full Title: Tolerance and immunological response in HIV seropositive individuals after NR100063 supplementation
    Medical condition: HIV infection
    Disease: Version SOC Term Classification Code Term Level
    6.1 10021881 SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-004693-87 Sponsor Protocol Number: 2004-04 Start Date*: 2004-11-03
    Sponsor Name:OSPEDALE SACRO CUORE-DON CALABRIA
    Full Title: Randomized study on therapy of Strongyloides stercoralis invasion: ivermectine VS thiabendazole
    Medical condition: Strongyloidiasis
    Disease: Version SOC Term Classification Code Term Level
    6.1 10021881 SOC
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2019-000801-61 Sponsor Protocol Number: ITM201901 Start Date*: 2019-05-09
    Sponsor Name:Institute of Tropical Medicine Antwerp
    Full Title: Toward an optimal accelerated Tick-Borne Encephalitis (TBE) vaccination schedule for the last-minute traveler
    Medical condition: Thick-Borne Encephalitis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2017-001798-18 Sponsor Protocol Number: C15-33 Start Date*: 2017-05-10
    Sponsor Name:Inserm
    Full Title: Partnership for Research on Ebola VACcinations P/0307/2021 P/0334/2021
    Medical condition: Ebola virus disease (EVD)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004862 10014074 Ebola virus infection LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2020-003391-40 Sponsor Protocol Number: 2020-KEP-456 Start Date*: 2020-12-17
    Sponsor Name:London School of Hygiene and Tropical Medicine
    Full Title: Intramuscular tranexamic acid for the treatment of symptomatic mild traumatic brain injury in older adults: a randomised, double-blind, placebo-controlled trial.
    Medical condition: Mild traumatic brain injury.
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10060690 Traumatic brain injury LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2009-017374-20 Sponsor Protocol Number: BNI-2009-01 Start Date*: 2010-04-19
    Sponsor Name:Bernhard-Nocht-Institute for Tropical Medicine
    Full Title: Probiotic Saccharomyces boulardii for the prevention of antibiotic-associated diarrhoea – randomised, double-blind, placebo-controlled trial
    Medical condition: Antibiotic - associated - Diarrhoea (AAD) Clostridium difficile - associated - Diarrhoea (CDAD)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10012748 Diarrhoea, Clostridium difficile LLT
    14.1 10021881 - Infections and infestations 10006835 C.difficile diarrhoea LLT
    14.1 10017947 - Gastrointestinal disorders 10055956 Antibiotic-associated diarrhoea LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-003192-19 Sponsor Protocol Number: ISRCTN11225767 Start Date*: 2013-02-22
    Sponsor Name:London School Of Hygiene and Tropical Medicine
    Full Title: Tranexamic acid for the treatment of gastrointestinal haemorrhage: an international randomised, double blind placebo controlled trial
    Medical condition: Gastrointestinal hemorrhage
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004856 10017960 Gastrointestinal hemorrhage LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) RO (Completed) ES (Prematurely Ended) IE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-024644-15 Sponsor Protocol Number: 2010-024644-15 Start Date*: 2012-02-07
    Sponsor Name:AZIENDA OSPEDALIERA UNIVERSITARIA DELLA SECONDA UNIVERSITA' DEGLI STUDI DI NAPOLI
    Full Title: Concomitant therapy with levofloxacyn versus sequential therapy with levofloxacin for eradication of H. pylori infection
    Medical condition: Helicobacter pylori infection
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10021881 Infections and infestations SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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