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Clinical trials for Uncontrolled Hypertension AND Hypertension

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    150 result(s) found for: Uncontrolled Hypertension AND Hypertension. Displaying page 1 of 8.
    1  2  3  4  5  6  7  8  Next»
    EudraCT Number: 2004-003847-37 Sponsor Protocol Number: REM 04 15 Start Date*: 2004-12-21
    Sponsor Name:BIOPROJET
    Full Title: An Open label uncontrolled study of the safety and efficacy of chronic intravenous Remodulin in patients with pulmonary Arterial Hypertension
    Medical condition: Pulmonary Arterial Hypertension
    Disease: Version SOC Term Classification Code Term Level
    6.1 10037400 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2009-017155-10 Sponsor Protocol Number: 10-aifa-2005-01 Start Date*: 2006-11-07
    Sponsor Name:CASA DI CURA PRIVATA S.RAFFAELE - PISANA
    Full Title: Evaluation of tolerability and efficacy of the combination Sildenafil/Bosentan in patients with severe pulmonary hypertension.
    Medical condition: severe pulmonary hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.0 10038738 - Respiratory, thoracic and mediastinal disorders 10037401 Pulmonary hypertensions HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-001690-84 Sponsor Protocol Number: CL3-05520-006 Start Date*: 2013-08-22
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Safety and efficacy of fixed dose combination of Indapamide SR 1.5 mg / Amlodipine versus Valsartan / Amlodipine over 12-week of treatment with conditional titration based on the blood pressure con...
    Medical condition: Uncontrolled essential hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 10047065 - Vascular disorders 10015488 Essential hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) HU (Completed) LT (Completed) LV (Completed) BG (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2006-000071-15 Sponsor Protocol Number: EMD-05-03 Start Date*: 2007-02-06
    Sponsor Name:Alcon Laboratories Inc.
    Full Title: Study of the Efficacy and Safety of Travatan Therapy compared with Cosopt Therapy in Patients with Open-Angle Glaucoma or Ocular Hypertension.
    Medical condition: Open-Angle Glaucoma or Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    8.1 10030043 Ocular hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-001890-42 Sponsor Protocol Number: CLHW090X2202 Start Date*: 2016-04-04
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A randomized, sponsor open, site and subject double-blind, parallel group, placebo-controlled study to evaluate the safety and efficacy of LHW090 after 4 weeks treatment in patients with resistant ...
    Medical condition: Resistant hypertension
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004866 10015491 Essential hypertension, unspecified LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) FR (Completed) DK (Completed) NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-001658-24 Sponsor Protocol Number: CL3-06593-006 Start Date*: 2013-03-12
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Efficacy and safety of fixed-dose combination Perindopril 5 mg / Indapamide 1.25 mg / Amlodipine 5 mg versus Perindopril 5 mg / Indapamide 1.25 mg single pill in patients with uncontrolled essentia...
    Medical condition: Uncontrolled essential hypertension
    Disease: Version SOC Term Classification Code Term Level
    15.0 10047065 - Vascular disorders 10015488 Essential hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Completed) CZ (Completed) HU (Completed) BG (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2012-000509-54 Sponsor Protocol Number: MB121-008 Start Date*: 2012-09-12
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Phase 2B Trial to Evaluate the Safety and Efficacy of BMS-823778 in Overweight and Obese Subjects with Inadequately Cont...
    Medical condition: Hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 10047065 - Vascular disorders 10020772 Hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2021-001404-14 Sponsor Protocol Number: QGC001-3QG2 Start Date*: 2021-08-17
    Sponsor Name:Quantum Genomics
    Full Title: A Phase 3, Double-blind, Placebo-controlled and Open-label Efficacy and Long-term Safety Study of Firibastat (QGC001) Administered Orally, Once Daily, for Up to 48 Weeks in Patients with Difficult-...
    Medical condition: Treatment of patients with difficult-to-treat and/or treatment-resistant hypertension (HTN)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004866 10036695 Primary hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Prematurely Ended) HU (Prematurely Ended) ES (Ongoing) CZ (Prematurely Ended) IT (Completed) NL (Prematurely Ended) BE (Completed) BG (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-002560-41 Sponsor Protocol Number: 0611 Start Date*: 2017-09-21
    Sponsor Name:University of Leicester
    Full Title: A Calcium channel or Angiotensin converting enzyme inhibitor/Angiotensin receptor blocker Regimen to reduce Blood pressure variability in acute ischaemic Stroke (CAARBS): A Feasibility Trial
    Medical condition: Participants in the trial will have had a transient ischaemic attack (TIA) or an acute ischaemic stroke and will also have hypertension. The trial will investigate the possible treatment of blood p...
    Disease: Version SOC Term Classification Code Term Level
    20.1 10029205 - Nervous system disorders 10060840 Ischaemic cerebral infarction PT
    20.0 10029205 - Nervous system disorders 10061256 Ischaemic stroke PT
    20.0 10029205 - Nervous system disorders 10044390 Transient ischaemic attack PT
    20.0 10047065 - Vascular disorders 10015488 Essential hypertension PT
    20.0 10047065 - Vascular disorders 10020772 Hypertension PT
    20.0 10047065 - Vascular disorders 10020783 Hypertension not adequately controlled LLT
    20.0 10047065 - Vascular disorders 10036695 Primary hypertension LLT
    20.0 10047065 - Vascular disorders 10066860 Uncontrolled hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-003928-37 Sponsor Protocol Number: BAY63-2521/12916 Start Date*: 2008-07-14
    Sponsor Name:Bayer AG
    Full Title: A multicenter, non-randomized, non-blinded, non-controlled study to investigate the impact of multiple doses of BAY 63-2521 on safety, tolerability, pharmacokinetics and pharmacodynamics in patient...
    Medical condition: Patients with interstitial lung disease associated pulmonary hypertension
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10037400 Pulmonary hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-001809-16 Sponsor Protocol Number: Unidone-01 Start Date*: 2016-09-14
    Sponsor Name:Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A.
    Full Title: Efficacy and safety of chlorthalidone 25 mg in hypertensive patients.
    Medical condition: BP lowering effect of chlorthalidone 25 mg in essential hypertensive patients.
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004866 10045866 Unspecified essential hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: View results
    EudraCT Number: 2007-002583-10 Sponsor Protocol Number: 01-06-TL-491-020 Start Date*: 2008-01-08
    Sponsor Name:Takeda Global Research & Development Centre (Europe) Ltd.
    Full Title: A Double-Blind, Randomized, Parallel-Group Study to Compare the Efficacy and Safety of TAK-491 With Ramipril in Subjects With Essential Hypertension
    Medical condition: According to the World Health Organization, hypertension (high blood pressure) is the most common attributable cause of preventable death in developed nations. When uncontrolled, hypertension is as...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015488 Essential hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) SE (Completed) EE (Completed) FI (Completed) SK (Completed) BG (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-020424-21 Sponsor Protocol Number: bbbipah.1 Start Date*: 2011-01-10
    Sponsor Name:VU medical center
    Full Title: Betablocker Therapy in Pulmonary Arterial Hypertension
    Medical condition: Idiopathic pulmonal arterial hypertension
    Disease: Version SOC Term Classification Code Term Level
    12.1 10020787 Hypertension pulmonary LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001596-23 Sponsor Protocol Number: KCT06/2017-PRECIOUS Start Date*: 2017-11-30
    Sponsor Name:Krka, d.d., Novo mesto
    Full Title: Fixed-Dose Combination of Perindopril/Amlodipine (Amlessa®) and Fixed-Dose Combination of Perindopril/Indapamide /Amlodipine (Co-Amlessa®) - Contribution to Management in newly diagnosed and uncont...
    Medical condition: Newly diagnosed and uncontrolled patients with essential arterial hypertension.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10047065 - Vascular disorders 10015488 Essential hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed) SI (Completed) HR (Completed)
    Trial results: View results
    EudraCT Number: 2021-000745-40 Sponsor Protocol Number: MEIN/20/ZoAm-Hyp/001 Start Date*: 2022-01-03
    Sponsor Name:MENARINI INTERNATIONAL OPERATIONS LUXEMBOURG SA
    Full Title: Interventional clinical trial to assess efficacy and safety of the extemporaneous combination of Zofenopril calcium and amlodipine in grade 1-2 hypertensive patients versus each monotherapy
    Medical condition: Grade 1-2 hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10047065 - Vascular disorders 10020772 Hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2021-005077-10 Sponsor Protocol Number: MEIN/21/AmNe-Hyp/001 Start Date*: 2022-04-28
    Sponsor Name:Menarini International Operations Luxembourg SA
    Full Title: Open-label, multicenter, multinational, interventional clinical trial to assess efficacy and safety of the extemporaneous combination of nebivolol and amlodipine in grade 1-2 hypertensive patients ...
    Medical condition: Grade 1-2 hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10047065 - Vascular disorders 10020772 Hypertension PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BG (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2009-017010-68 Sponsor Protocol Number: 1235.34 Start Date*: 2010-07-21
    Sponsor Name:Universitätsmedizin der Johannes Gutenberg-Universität Mainz
    Full Title: A TElmisartan and AMlodipine STudy to Assess the cardiovascular PROTECTive effects as measured by endothelial dysfunction in hypertensive at risk patients beyond blood pressure
    Medical condition:  Male and female, treated and treatment-naive patients with uncontrolled hypertension (defined as 20/10 mmHg above target BP of <140/90 mmHg [<130/80 mmHg for renally impaired and/ or diabetics pa...
    Disease: Version SOC Term Classification Code Term Level
    13.1 10047065 - Vascular disorders 10020772 Hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-004891-16 Sponsor Protocol Number: CL3-05179-002 Start Date*: 2021-10-20
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Evaluation of the clinical efficacy and safety of perindopril 10 mg/indapamide 2.5 mg/amlodipine 5 or 10 mg/bisoprolol 5 mg in single-pill combination after 8 weeks of treatment versus the free com...
    Medical condition: Hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10047065 - Vascular disorders 10020772 Hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed) PT (Completed) LT (Completed) IT (Completed) LV (Completed) SK (Completed) HU (Completed) CZ (Completed) BG (Completed) HR (Completed)
    Trial results: View results
    EudraCT Number: 2020-002340-23 Sponsor Protocol Number: MEIN/19/ZoNe-HYP/001 Start Date*: 2021-04-20
    Sponsor Name:MENARINI INTERNATIONAL OPERATIONS LUXEMBOURG SA
    Full Title: Open-label, multicenter, multinational, interventional clinical trial to assess effectiveness and safety of the extemporaneous combination of nebivolol and zofenopril calcium in grade 1 to 2 hypert...
    Medical condition: Grade 1 and 2 hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10047065 - Vascular disorders 10020772 Hypertension PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2017-003672-31 Sponsor Protocol Number: KCT05/2017-UNIFY Start Date*: 2019-01-03
    Sponsor Name:KRKA, d.d., Novo mesto
    Full Title: Fixed-dose combination of rosuvastatin and valsartan for dual target achievement in patients with hypertension and hyperlipidaemia (UNIFY)
    Medical condition: Patients with mild to moderate essential arterial hypertension AND primary hypercholesterolemia or mixed dyslipidaemia (LDL-c < 4.9 mmol/L or <189.5 mg/dl) with moderate, high or very high risk for...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10062060 Hyperlipidaemia PT
    20.0 10047065 - Vascular disorders 10015488 Essential hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
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