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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44338   clinical trials with a EudraCT protocol, of which   7368   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    10,988 result(s) found. Displaying page 268 of 550.
    EudraCT Number: 2004-000254-23 Sponsor Protocol Number: ATL 962/175/CL Start Date*: 2004-11-09
    Sponsor Name:Alizyme Therapeutics Limited
    Full Title: A Phase II Multicentre, Double Blind, Placebo Controlled, Parallel Group, Dose Ranging Study of ATL 962 to Assess Weight Loss, Safety and Tolerability in Obese Patients with Type II Diabetes being ...
    Medical condition: Treatment of obesity in patients with Type II diabetes
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed) SE (Completed) GB (Completed) DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004296-11 Sponsor Protocol Number: EOP 1010B Start Date*: 2005-07-12
    Sponsor Name:(OSI) Eyetech Pharamceuticals Inc
    Full Title: An open label, non-comparative protocol for the use of pegaptanib sodium injection every 6 weeks in patients with exudative age-related macular degeneration (AMD).
    Medical condition: Exudative Age Related Macular Degeneration (AMD)
    Disease: Version SOC Term Classification Code Term Level
    8 10025411 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) PT (Completed) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-001854-10 Sponsor Protocol Number: BO18039 Start Date*: 2005-02-16
    Sponsor Name:F. Hoffmann-La Roche Ltd
    Full Title: Randomized, two arm, placebo controlled double dummy study to compare the efficacy of intravenous loading doses followed by maintenance treatment with oral ibandronic acid versus zoledronic acid in...
    Medical condition: Metastatic Bone Pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) GB (Completed) DE (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-000822-30 Sponsor Protocol Number: 205.346 Start Date*: 2006-10-25
    Sponsor Name:Boehringer Ingelheim Pharma GmbH
    Full Title: A randomized, double-blind, double-dummy, parallel group trial comparing 12 weeks treatment with tiotropium inhalation capsules 18 mcg via the HandiHaler® once daily to Combivent® Inhalation Aeroso...
    Medical condition: Chronic Obstructive Pulmonary Disease (COPD) including chronic bronchitis and emphysema
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Completed) LT (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-003649-18 Sponsor Protocol Number: V232-059-00 Start Date*: 2007-01-12
    Sponsor Name:Merck & Co. Inc.
    Full Title: A Study in Healthy Adults of the Safety, Tolerability, and Immunogenicity of Recombinant Hepatitis B Vaccine Manufactured With a Modified Process
    Medical condition: Hepatitis B
    Disease: Version SOC Term Classification Code Term Level
    8.1 10019731 Hepatitis B LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) GB (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2005-001150-24 Sponsor Protocol Number: HPR20001 Start Date*: 2005-07-28
    Sponsor Name:GlaxoSmithKline Research & Development Ltd.
    Full Title: A Phase IIB, Randomized, Multicenter, Parallel Group Study to Evaluate the Short-Term Safety, Pharmacokinetics and Antiviral Activity of Four Blinded Dosing Regimens of GW640385/Ritonavir Therapy C...
    Medical condition: Treatment of HIV-1 infection.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed) DE (Prematurely Ended) IT (Prematurely Ended) PT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-004110-32 Sponsor Protocol Number: D1521C00002 Start Date*: 2005-12-01
    Sponsor Name:AstraZeneca AB
    Full Title: A Randomised, Double-blind, Placebo-controlled, Parallel Group, Multicentre, Phase II Study to Assess The Efficacy of AZD9056 (single oral 400 mg dose) when Administered for 4 Weeks in Patients wit...
    Medical condition: Chronic Obstructive Pulmonary Disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) SE (Completed) HU (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-002212-13 Sponsor Protocol Number: VEG102616 Start Date*: 2006-08-08
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: A Phase II Study of GW786034 Using a Randomized Discontinuation Design in Subjects with Locally Recurrent or Metastatic Clear-Cell Renal Cell Carcinoma
    Medical condition: Locally Recurrent or Metastatic Clear-Cell Renal Cell Carcinoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) CZ (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2005-004168-21 Sponsor Protocol Number: CQAB149B2328 Start Date*: 2006-01-30
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A 52-week treatment, multicenter, randomized, double-blind, double dummy, placebo-controlled, parallel-group study to assess the efficacy, safety and tolerability of indacaterol (200 & 400 µg o.d.)...
    Medical condition: Chronic obstructive pulmonary disease (COPD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) SE (Prematurely Ended) DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-000176-32 Sponsor Protocol Number: CGX-635-CML-202 Start Date*: 2006-09-22
    Sponsor Name:Stragen France
    Full Title: A Phase II Open-Label Study of the Subcutaneous Administration of Homoharringtonine (Omacetaxine) (CGX-635) in the Treatment of Patients with Chronic Myeloid Leukemia (CML) with the T315I BCR-ABL G...
    Medical condition: Chronic Myeloid Leukaemia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed) HU (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-003299-12 Sponsor Protocol Number: C0524T09 Start Date*: 2006-04-26
    Sponsor Name:Janssen Biologics B.V.
    Full Title: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial of Golimumab, a Fully Human Anti-TNFalfa Monoclonal Antibody, Administered Subcutaneously, in Subjects with Active Ankylosing Spond...
    Medical condition: Ankylosing Spondylitis (AS)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) DE (Completed) GB (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2005-005377-29 Sponsor Protocol Number: CNS 2004 03 Start Date*: 2006-05-03
    Sponsor Name:Dept of Pediatrics, University Hospital of North Norway
    Full Title: SIOP-LGG 2004 Cooperative multicenter Study for Children and Adolescents with Low Grade Gliome
    Medical condition: Low Grade Glioma
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NO (Ongoing) IE (Completed) GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-004835-23 Sponsor Protocol Number: TON/01/05-CLIN Start Date*: 2006-01-26
    Sponsor Name:Minster Pharmaceuticals Ltd
    Full Title: Multi-centre, parallel group, double-blind, placebo controlled study of the efficacy and tolerability of TONABERSAT in prophylaxis of migraine headache
    Medical condition: Migraine with or without aura meeting the diagnostic criteria of the International Classification of Headache Disorders (Edition 2).
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed) DK (Completed) GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2006-001688-49 Sponsor Protocol Number: ALS-GA-201 Start Date*: 2006-08-14
    Sponsor Name:TEVA Pharmaceutical Industries. Ltd.
    Full Title: A multi-national, multi-centre, randomized, double-blind, placebo-controlled, parallel-group study to assess the efficacy, tolerability and safety of 40 mg glatiramer acetate injection in subjects ...
    Medical condition: Early stage of amyotrophic lateral sclerosis (ALS)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10002026 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) BE (Completed) DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-000860-10 Sponsor Protocol Number: 10729 Start Date*: 2006-06-30
    Sponsor Name:H. Lundbeck A/S
    Full Title: An Open-Label Study Investigating the Specific Effects of Memantine in Institutionalised Patients with Alzheimer’s Disease
    Medical condition: Effects of memantine treatment in institutionalised patients with Alzheimer's Disease.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended) BE (Completed) GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2005-005099-33 Sponsor Protocol Number: CA165-026 Start Date*: 2006-12-13
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: A Three Cohort Phase II Trial of BMS-275183 Given Orally on a Twice Weekly Schedule in Pretreated Locally Advanced or Metastatic NSCLC Patients + Pharmacogenetics Blood Sample Amendment Number 01 ...
    Medical condition: Patients with pretreated locally advanced or metastatic Non-small Cell Lung Cancer (NSCLC)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) GB (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-005926-22 Sponsor Protocol Number: FLT3501 Start Date*: 2007-03-14
    Sponsor Name:Mundipharma Research Ltd.
    Full Title: An open, randomised, parallel group, multicentre study to compare the efficacy and safety of FlutiForm pMDI vs Seretide pMDI in adult subjects with mild to moderate-severe persistent, reversible as...
    Medical condition: Asthma bronchial
    Disease: Version SOC Term Classification Code Term Level
    8.1 10003555 Asthma bronchial LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2005-000963-25 Sponsor Protocol Number: A1481156 Start Date*: 2005-05-30
    Sponsor Name:Pfizer Limited, Ramsgate Road, Sandwich, Kent, UK
    Full Title: A Multicenter, Long-Term Extension Study to Assess Safety of Oral Sildenafil in the Treatment of Subjects Who Have Completed Study A1481131
    Medical condition: Pulmonary Arterial Hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10064911 Pulmonary arterial hypertension PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: SE (Completed) GB (Completed) FI (Prematurely Ended) SK (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2005-000837-39 Sponsor Protocol Number: CCD01 Start Date*: 2007-08-15
    Sponsor Name:Cytonet GmbH & Co. KG
    Full Title: Open, randomized, prospective, controlled, multicentre study to evaluate the efficacy and safety of multiple intraportal applications of liver cell suspension in patients with acute liver failure n...
    Medical condition: Acute Liver Failure Subgroups of patients with indications falling under ICD classification codes:K70.4, K71, K72, K75, K76, K77
    Disease: Version SOC Term Classification Code Term Level
    9.1 10049844 Acute liver failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) GB (Prematurely Ended) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-006459-10 Sponsor Protocol Number: KU36-58 Start Date*: 2007-07-18
    Sponsor Name:KuDOS Pharmaceuticals Ltd. (a member of the AstraZeneca group of companies)
    Full Title: A phase II, open-label, non-comparative, international, multicentre study to assess the efficacy and safety of KU 0059436 given orally twice daily in patients with advanced BRCA1- or BRCA2-associat...
    Medical condition: Advanced ovarian cancer (stage IIIB/IIIC/IV) and confirmed BRCA+ status
    Disease: Version SOC Term Classification Code Term Level
    9.1 10033128 Ovarian cancer LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DE (Completed) SE (Completed) ES (Completed) GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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