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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44381   clinical trials with a EudraCT protocol, of which   7393   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    26,035 result(s) found. Displaying page 692 of 1,302.
    EudraCT Number: 2009-015586-31 Sponsor Protocol Number: 190342-031D Start Date*: 2010-01-29
    Sponsor Name:Allergan Limited
    Full Title: A Multicenter, Masked, Randomized, Sham-Controlled, Parallel-Group, 3 Month Study with a 9-Month Safety Extension to Evaluate the Safety and Efficacy of Brimonidine Tartrate Posterior Segment Drug ...
    Medical condition: Rhegmatogenous Macula-off Retinal Detachment
    Disease: Version SOC Term Classification Code Term Level
    12.1 10065569 Rhegmatogenous retinal detachment LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-000456-13 Sponsor Protocol Number: ML20006.XEBERECTO/ICO/005 Start Date*: 2007-07-11
    Sponsor Name:Institut Català d'Oncologia (ICO)
    Full Title: Estudio fase II de Bevacizumab en combinación con Capecitabina y radioterapia como tratamiento preoperatorio en pacinetes con cáncer rectal localmente avanzado resecable.
    Medical condition: Cancer rectal localmente avanzado
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038038 Rectal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-016041-25 Sponsor Protocol Number: RGH-MD-36 Start Date*: 2010-05-12
    Sponsor Name:Forest Research Institute, Inc.
    Full Title: A Long-Term Open-label Study of the Safety and Tolerability of Cariprazine in Patients With Bipolar I Disorder
    Medical condition: Bipolar I disorder
    Disease: Version SOC Term Classification Code Term Level
    12.0 10004939 Bipolar I disorder PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) ES (Prematurely Ended) HU (Completed)
    Trial results: View results
    EudraCT Number: 2009-017665-31 Sponsor Protocol Number: CSE Start Date*: 2010-09-30
    Sponsor Name:AZIENDA OSPEDALIERA MAGGIORE DELLA CARITA` DI NOVARA
    Full Title: Effect on mother and fetus of epidural and combined spinal-epidural techniques for labour analgesia
    Medical condition: Labour
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-018486-37 Sponsor Protocol Number: dexa2010 Start Date*: 2010-05-21
    Sponsor Name:Kris-och Traumacentrum
    Full Title: Treatment of exacerbations of post-traumatic stress disorder by short-term dexamethasone, a pilot study.
    Medical condition: Posttraumatic stress syndrome F431
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016653-17 Sponsor Protocol Number: FARM73452X Start Date*: 2010-04-13
    Sponsor Name:AZIENDA UNITA` SANITARIA LOCALE N 12 DI VIAREGGIO
    Full Title: TREATMENT OF HYPOTENSION IN EXTREMELY PRETERM INFANTS: A MULTICENTER RANDOMIZED CONTROLLED TRIAL
    Medical condition: HYPOTENSION IN EXTREMELY PRETERM INFANTS
    Disease: Version SOC Term Classification Code Term Level
    9.1 10049223 LLT
    9.1 10049223 LLT
    9.1 10049223 LLT
    9.1 10049223 LLT
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-018146-38 Sponsor Protocol Number: MFN09/15 Start Date*: 2010-05-28
    Sponsor Name:Swedish Orphan International AB
    Full Title: Multicenter randomized controlled study comparing the efficacy and safety of natural Multi-subtype interferon alpha (Multiferon) in association with ribavirin versus retreatment with pegylated inte...
    Medical condition: Hepatitis C
    Disease: Version SOC Term Classification Code Term Level
    12.1 10019744 Hepatitis C LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-018529-21 Sponsor Protocol Number: 25286464463845 Start Date*: 2010-05-12
    Sponsor Name:Karolinska Institutet, Institution CLINTEC, enheten för anestesi
    Full Title: Albuminkinetik vid generell inflammation en explorativ studie på patienter vid stor bukkirurgi
    Medical condition: General inflammation and systemic inflammatory response syndrome (SIRS) due to large abdominal surgery
    Disease: Version SOC Term Classification Code Term Level
    12.1 10021995 Inflammatory reaction LLT
    12.1 10051379 Systemic inflammatory response syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2008-003982-21 Sponsor Protocol Number: P080402 Start Date*: 2010-06-10
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Etude des transporteurs de la dopamine et de la sérotonine en imagerie TEMP utilisant les radiopharmaceutiques 123I-FP-CIT (datscan) and 123 I-ADAM dans la sclérose latérale amyotrophique et dans u...
    Medical condition: Patients présentant une SLA et volontaires sains
    Disease: Version SOC Term Classification Code Term Level
    8.1 10002026 Amyotrophic lateral sclerosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2009-018117-40 Sponsor Protocol Number: CLAF237AFR02 Start Date*: 2010-03-09
    Sponsor Name:Novartis Pharma S.A.S
    Full Title: Etude prospective, randomisée, comparant les profils glycémiques sur 72 hr obtenus par enregistrement continu du glucose (CSGM) chez des patients diabétiques de type 2 insuffisamment contrôlés par ...
    Medical condition: Diabète de type II
    Disease: Version SOC Term Classification Code Term Level
    12.1 10012601 Diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2009-016813-11 Sponsor Protocol Number: AOBS-RT-TMZ Start Date*: 2010-01-22
    Sponsor Name:AZIENDA OSPEDALIERA SPEDALI CIVILI DI BRESCIA
    Full Title: Randomized prospectic clinical trial Phase II in patients affected by prognostic class RPA V and VI glioblastoma: comparison between hypofractionated radiotherapy (RT) 30 Gy (6 fractions in two wee...
    Medical condition: Patients with histological diagnosis od glioblastoma in RPA class V and VI and age =>65 yrs.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029104 SOC
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-010788-18 Sponsor Protocol Number: CAMMS03409 Start Date*: 2009-07-01
    Sponsor Name:Genzyme Corporation
    Full Title: An Extension Protocol For Multiple Sclerosis Patients Who Participated in Genzyme-Sponsored Studies of Alemtuzumab
    Medical condition: Relapsing Remitting Multiple Sclerosis
    Disease: Version SOC Term Classification Code Term Level
    17.0 10029205 - Nervous system disorders 10063399 Relapsing-remitting multiple sclerosis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) BE (Completed) SE (Completed) AT (Completed) PL (Completed) CZ (Completed) NL (Completed) DK (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2009-016962-10 Sponsor Protocol Number: GOIRC 02/2009 Start Date*: 2010-02-12
    Sponsor Name:GRUPPO ONCOLOGICO ITALIANO DI RICERCA
    Full Title: First Line Dose-Dense Chemotherapy With Docetaxel, Cisplatin, Folinic Acid and 5- Fluorouracil plus Panitumumab in Patients With Locally Advanced or Metastatic Cancer of the Stomach or Gastro-Esoph...
    Medical condition: Patients with metastatic or locally advanced not resectable cancer of the stomach or gastro-esophageal junction.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10017758 PT
    9.1 10030176 HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-014732-38 Sponsor Protocol Number: ML25042 Start Date*: 2010-03-24
    Sponsor Name:SOGUG
    Full Title: Ensayo clínico fase IV.II para el análisis de los factores moleculares de pronóstico de respuesta y beneficio clínico en pacientes con cáncer renal metastásico o avanzado, tratados con bevacizumab ...
    Medical condition: Cáncer renal metastásico o avanzado
    Disease: Version SOC Term Classification Code Term Level
    9 10050018 Renal cancer metastatic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017441-63 Sponsor Protocol Number: PRGT-PPT Start Date*: 2010-06-30
    Sponsor Name:U.O. Ginecologia e Ostetricia
    Full Title: EVALUATION OF PROGESTERONE-RELATED COMPOUNDS FOR THE TERZIARY PROPHILAXYS OF PRETERM DELIVERY: A MULTICENTRE RANDOMIZED CONTROLLED TRIAL
    Medical condition: THREATENED PRETERM DELIVERY
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036585 SOC
    Population Age: Adults Gender: Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-018335-17 Sponsor Protocol Number: CSM/Fusión/2009 Start Date*: 2010-07-20
    Sponsor Name:Fundación de la Universidad de Salamanca
    Full Title: Ensayo clínico en fase I/II prospectivo, abierto, no aleatorizado para el tratamiento de la discopatía degenerativa intervertebral lumbar mediante artrodesis posterolateral instrumentada y células ...
    Medical condition: Discopatía degenerativa intervertebral lumbar
    Disease: Version SOC Term Classification Code Term Level
    9 10012153 Degeneration of lumbar or lumbosacral intervertebral disc LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-018108-17 Sponsor Protocol Number: PAC_2009 Start Date*: 2010-03-24
    Sponsor Name:Medizinische Universität Graz
    Full Title: Kann der antiaggregatorische Effekt von Clopidogrel und Acetylsalicylsäure durch die Gabe von Thrombozytenkonzentraten aufgehoben werden?
    Medical condition: Studie an gesunden Probanden. Zweck dieser Studie: Können autologe Thrombozyten-Konzentrate die Wirkung von Clopidogrel und Acetylsalicylsäure aufheben?
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: Removed from public view
    EudraCT Number: 2009-016966-97 Sponsor Protocol Number: CAD01 Start Date*: 2010-06-08
    Sponsor Name:Universitätsklinikum Essen
    Full Title: Therapy for Chronic Cold Agglutinin Disease: A Prospective, Non-Randomized, Multi-Center Study Demonstrating the Efficacy of Terminal Complement Inhibition in Patients with Cold Agglutinin Disease ...
    Medical condition: Cold agglutinin disease
    Disease: Version SOC Term Classification Code Term Level
    12.1 10009868 Cold type haemolytic anaemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-017407-28 Sponsor Protocol Number: H 527 000-0917 Start Date*: 2010-01-27
    Sponsor Name:Almirall Hermal GmbH
    Full Title: A phase II, single-center, randomized, controlled, double-blind study to assess effects on skin conditions and patient reported outcome of a topical formulation containing LAS41002 on lesional skin...
    Medical condition: Clinical condition of atopic eczema mild to moderate defined by a local SCORAD of at least 5 with • erythma ≥ 2 • lichenification ≥ 1 • dryness ≥ 1 • itching ≥ 1 • Erlangen atopy score sum equal...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10003639 Atopic dermatitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-010625-39 Sponsor Protocol Number: MZ09-PCP-SosPeter Start Date*: 2010-04-21
    Sponsor Name:Prague Psychiatric Center
    Full Title: QEEG cordance and EEG connectivity changes after administration of subanesthetic ketamine doses in depressive disorder patients
    Medical condition: INCLUSION CRITERIA: 1. Men and women at the age between 18 to 65 years, with dextromanual dominance. 2. Patients have to answer DSM IV criteria for the major depressive episode, without psychotic s...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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