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Clinical trials for Type 2 diabetes

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    2,112 result(s) found for: Type 2 diabetes. Displaying page 10 of 106.
    EudraCT Number: 2009-015760-33 Sponsor Protocol Number: P090303 Start Date*: 2009-11-17
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Effet de différents schémas d'insulinothérapie sur la compliance artérielle, la fonction endothéliale et la fonction autonome cardiaque de patients diabétiques de type 2 mal équilibrés sous traitem...
    Medical condition: Diabéte de type 2 mal équilibré
    Disease: Version SOC Term Classification Code Term Level
    8.1 10012613 Diabetes mellitus non-insulin-dependent PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-020015-36 Sponsor Protocol Number: Nauck-DZBL-2010-1 Start Date*: 2011-04-15
    Sponsor Name:Diabeteszentrum Bad Lauterberg
    Full Title:
    Medical condition: Diabetes mellitus Type II
    Disease: Version SOC Term Classification Code Term Level
    13.1 10027433 - Metabolism and nutrition disorders 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2014-004760-37 Sponsor Protocol Number: NA Start Date*: 2015-12-23
    Sponsor Name:Riitta Veijola
    Full Title: Incretin-based therapy in non-symptomatic, early diagnosed type 1 diabetics
    Medical condition: Type 1 diabetes
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004861 10045228 Type I diabetes mellitus LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-015398-11 Sponsor Protocol Number: PKPD_SQ_1 Start Date*: 2009-11-03
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: Pharmacokinetic and pharmacodynamic profile of rapid-acting insulin injected by needle-free jet-injection
    Medical condition: type 1 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    12.0 10045228 Type I diabetes mellitus LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2011-001696-39 Sponsor Protocol Number: AKF 379 Start Date*: 2011-07-06
    Sponsor Name:University of Southern Denmark, Clinical Pharmacology
    Full Title: The inhibitory effect of metformin on gluconeogenesis in relation to polymorphisms in Organic Cation Transporter 1 (OCT1) in healthy volunteers
    Medical condition: Healthy volunteers (diabetes mellitus 2)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10027433 - Metabolism and nutrition disorders 10045242 Type II diabetes mellitus LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2007-005883-28 Sponsor Protocol Number: EFC6019 Start Date*: 2008-05-19
    Sponsor Name:Sanofi-Aventis Recherche & Développement
    Full Title: A randomized, open-label, active-controlled, 2-arm parallel-group, multicenter 24-week study followed by an extension assessing the efficacy and safety of AVE0010 versus exenatide on top of metform...
    Medical condition: Type II Diabetes
    Disease: Version SOC Term Classification Code Term Level
    10.1 10067585 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) FI (Completed) DE (Completed) ES (Completed) DK (Completed) HU (Completed) NL (Completed) GR (Completed) IT (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2017-003911-21 Sponsor Protocol Number: 23092017 Start Date*: 2018-05-11
    Sponsor Name:University of Oxford
    Full Title: Dapagliflozin during exercise for the prevention of hypoglycaemia in Type 1 diabetes
    Medical condition: Type 1 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10067584 Type 1 diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2010-022193-13 Sponsor Protocol Number: 3102-006-00 Start Date*: 2010-11-22
    Sponsor Name:MSD Finland Oy
    Full Title: A Phase IIb, Randomized, Placebo-Controlled, Dose-Range Finding Clinical Trial to Study the Safety and Efficacy of MK-3102 in Patients with Type 2 Diabetes Mellitus and Inadequate Glycemic Control
    Medical condition: Type 2 Diabetes Mellitus
    Disease: Version SOC Term Classification Code Term Level
    12.1 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) LV (Completed) DE (Completed) LT (Completed) FR (Completed) ES (Completed) DK (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2006-002090-47 Sponsor Protocol Number: 0533-005 Start Date*: 2006-07-07
    Sponsor Name:Merck & Co., Inc.
    Full Title: An Efficacy and Tolerability Study of MK-0533 in Patients with Type II Diabetes Mellitus Who Have Inadequate Glycemic Control.
    Medical condition: Type II Diabetes
    Disease: Version SOC Term Classification Code Term Level
    7.1 10012613 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Prematurely Ended) HU (Prematurely Ended) DE (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-002117-46 Sponsor Protocol Number: 08-BO-LSBE Start Date*: 2008-07-22
    Sponsor Name:Medizinische Klinik I, St. Josef-Hospital, Ruhr-Universität Bochum
    Full Title: Veränderungen der endogenen Insulin- und Glukagonsekretion während einer basalen Insulin-Substitution
    Medical condition: Diabetes mellitus Typ 2
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-007027-14 Sponsor Protocol Number: C06-27 Start Date*: 2007-11-27
    Sponsor Name:INSERM
    Full Title: Influence du traitement par Pioglitazone sur l'Ostéoprotégérine dans le diabète de tye II
    Medical condition: Diabète de type II
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-001209-28 Sponsor Protocol Number: RXQ425 Start Date*: 2011-07-21
    Sponsor Name:Buckinghamshire Healthcare NHS Trust
    Full Title: Impact of insulin detemir versus insulin glargine on glycaemic control and metabolism during exercise in Type 1 diabetes
    Medical condition: Type 1 Diabetes
    Disease: Version SOC Term Classification Code Term Level
    14.0 10027433 - Metabolism and nutrition disorders 10067584 Type 1 diabetes mellitus PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2017-002014-31 Sponsor Protocol Number: NN1218-4371 Start Date*: 2017-10-26
    Sponsor Name:Novo Nordisk A/S
    Full Title: A trial comparing the pharmacokinetic properties of fast-acting insulin aspart between children, adolescents and adults with type 1 diabetes
    Medical condition: Diabetes Mellitus, Type 1
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004861 10045228 Type I diabetes mellitus LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-007070-30 Sponsor Protocol Number: glipizide PKPD Start Date*: 2007-06-07
    Sponsor Name:Stockholms Läns Landsting
    Full Title: Farmakokinetik och effekt av glipizid på insulin och glukos hos patienter med nyupptäckt typ 2-diabetes mellitus
    Medical condition: diabetes mellitus typ 2
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-007031-27 Sponsor Protocol Number: INS-001 Start Date*: 2007-04-17
    Sponsor Name:Karolinska Institute
    Full Title: Effects of insulin treatment on postprandial platelet activation in patients with NIDDM: a placebo-controlled dose-response study with insulin aspart (Novorapid®)
    Medical condition: Patients with type 2 diabetes mellitus below 70 years of age and without a history of cardiovascular disease.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2013-002233-37 Sponsor Protocol Number: NN1218-3931 Start Date*: 2013-10-14
    Sponsor Name:Novo Nordisk A/S
    Full Title: A 6-week randomised, double-blind, parallel-group trial evaluating compatibility and safety of FIAsp and insulin aspart with an external continuous subcutaneous insulin infusion system in adult sub...
    Medical condition: Diabetes Mellitus, Type 1
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004861 10045228 Type I diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-002456-41 Sponsor Protocol Number: 1218.15 Start Date*: 2008-05-13
    Sponsor Name:Boehringer-Ingelheim Ellas AE
    Full Title: A randomised, double-blind, placebo controlled, parallel group 24 week study to assess the efficacy and safety of BI 1356 (5 mg) in combination with 30 mg pioglitazone (both administered orally onc...
    Medical condition: Patients with type 2 Diabetes Mellitus with insufficient glycaemic control.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed) HU (Completed) PT (Completed) AT (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2007-005899-13 Sponsor Protocol Number: GEN-084-OL Start Date*: 2008-06-24
    Sponsor Name:Generex Biotechnology Corp.
    Full Title: A 26-Week, Open-Label, Randomized, Active Comparator Study of Generex Oral-lyn™ Spray and Injected Human Insulin In Subjects With Type-1 Diabetes Mellitus
    Medical condition: type 1 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045228 Type I diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-002267-15 Sponsor Protocol Number: GluST1_vers4_2014 Start Date*: 2014-07-31
    Sponsor Name:Hvidovre Hospital
    Full Title: Treatment of hypoglycemia with glucagon among patients with type 1 diabetes mellitus
    Medical condition: Patients with type 1 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004861 10012608 Diabetes mellitus insulin-dependent LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-022513-26 Sponsor Protocol Number: SKY1052-2-001 Start Date*: 2011-02-22
    Sponsor Name:SkyePharma AG
    Full Title: Randomised, single-blind, placebo controlled, four-period four-treatment cross-over design, proof of concept study to compare the pharmacodynamic, safety and pharmacokinetics of one single administ...
    Medical condition: Type 1 Diabetes Mellitus
    Disease: Version SOC Term Classification Code Term Level
    12.1 10012601 Diabetes mellitus LLT
    12.1 10012608 Diabetes mellitus insulin-dependent LLT
    12.1 10012610 Diabetes mellitus loss of control LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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