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Clinical trials for Knee Osteoarthritis

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
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    The EU Clinical Trials Register currently displays   44338   clinical trials with a EudraCT protocol, of which   7368   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    260 result(s) found for: Knee Osteoarthritis. Displaying page 11 of 13.
    «« First « Previous 5  6  7  8  9  10  11  12  13  Next»
    EudraCT Number: 2018-004730-15 Sponsor Protocol Number: R5069-OA-1849 Start Date*: 2019-08-08
    Sponsor Name:Regeneron Pharmaceuticals, Inc.
    Full Title: A Randomized, Double-Blind, Multi-Dose, Placebo-Controlled Study to Evaluate the Efficacy and Safety of REGN5069 in Patients with Pain due to Osteoarthritis of the Knee
    Medical condition: Pain due to osteoarthritis of the knee
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) PL (Prematurely Ended) BG (Prematurely Ended) ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-003956-20 Sponsor Protocol Number: 2003-35-RTA-3 Start Date*: 2005-03-09
    Sponsor Name:HEXAL AG
    Full Title: Multi-center, double-blind, double-dummy, controlled, randomized phase III study on the tolerability and efficacy of Diclofenac Sodium 150 mg o.d. in comparison to Voltaren® 50 t.i.d. and Voltaren®...
    Medical condition: Symptomatic treatment for pain and inflammation associated with irritations of degenerative joint diseases, e.g. ostheoarthitis of the hip, knee or fingers
    Disease: Version SOC Term Classification Code Term Level
    7.1 10031161 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed) LV (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-018029-57 Sponsor Protocol Number: LT-NS001-003 Start Date*: 2010-04-26
    Sponsor Name:Logical Therapeutics Inc.
    Full Title: A Double-Blind, Double-Dummy, Randomized, Active-Comparator, Arthritis Non-Inferiority Study of LT-NS001 versus Naprosyn® for Twelve Weeks in Osteoarthritis Patients to Compare Endoscopic Gastric U...
    Medical condition: osteoarthritis of the knee
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-005596-90 Sponsor Protocol Number: NL51548.100.14 Start Date*: 2015-04-22
    Sponsor Name:St. Lucas Andreas Hospital
    Full Title: Comparison of femoral nerve block with posterior capsule infiltration versus anterior and posterior capsule infiltration after total knee replacement.
    Medical condition: patienst requiring total knee replacement for non-inflammatory osteoarthritis of the knee
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-003286-17 Sponsor Protocol Number: CCOX189A2428 Start Date*: 2006-01-04
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A 4-week, multicentre, randomized, double-blind, double-dummy, parallel group ambulatory blood pressure monitoring study to demonstrate that treatment with lumiracoxib 100 mg o.d. results in an imp...
    Medical condition: Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    8.0 10031161 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) SE (Completed) GB (Completed) FI (Completed)
    Trial results: View results
    EudraCT Number: 2005-002735-27 Sponsor Protocol Number: R30-05-01 Start Date*: 2005-09-19
    Sponsor Name:Fidia Farmaceutici SpA
    Full Title: A multicentre study to assess the safety and efficacy of sodium hyaluronate (Hyalgan-F) produced by fermentation in knee psteoarthritis.
    Medical condition: Knee oasteoarthritis
    Disease:
    Population Age: Adults, Elderly Gender:
    Trial protocol: LV (Completed)
    Trial results: View results
    EudraCT Number: 2016-003154-32 Sponsor Protocol Number: N/A Start Date*: 2017-09-18
    Sponsor Name:University of Leeds
    Full Title: SPAARK: Study of Peri-Articular Anaesthetic for Replacement of the Knee. The clinical and cost effectiveness of peri-articular liposomal bupivacaine compared with bupivacaine hydrochloride alone fo...
    Medical condition: Local anaesthetic for patients undergoing knee replacement surgery for arthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2009-011492-73 Sponsor Protocol Number: 13.09 Start Date*: 2009-09-28
    Sponsor Name:Swindon and Marlborough NHS Foundation Trust
    Full Title: Analysis of Blood Loss With the Use of Fibrin Sealant in Total Knee Replacement Surgery – A Randomised Controlled Study
    Medical condition: Blood loss in total knee arthroplasty
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2010-023888-17 Sponsor Protocol Number: OMS103-MEN-003 Start Date*: 2011-05-11
    Sponsor Name:Omeros Corporation
    Full Title: A Randomized, Double-Blind, Parallel Group, Vehicle-Controlled Study to Evaluate the Safety and Efficacy of OMS103HP-S Administered in Joint Irrigation Solution to Subjects Undergoing Arthroscopic ...
    Medical condition: Arthroscopic surgery
    Disease: Version SOC Term Classification Code Term Level
    13.1 10042613 - Surgical and medical procedures 10058471 Arthroscopic surgery PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-003556-39 Sponsor Protocol Number: DARINA Start Date*: 2012-06-05
    Sponsor Name:Martini Hospital Groningen
    Full Title: A randomized pilot study comparing the safety of DAbigatran and RIvaroxaban versus NAdroparin in the prevention of venous thromboembolism after knee arthroplasty surgery. DARINA
    Medical condition: After total knee arthroplasty (TKA) surgery, patients are at risk to develop venous thromboembolism (VTE). Two novel agents, dabigatran and rivaroxaban, recently gained market authorisation for pre...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-015532-14 Sponsor Protocol Number: EMR700692-003 Start Date*: 2010-01-22
    Sponsor Name:Merck Serono S.A. - Geneva
    Full Title: A multicenter, randomized, double-blind, placebo-controlled, parallel-group phase II trial to investigate the efficacy and safety of weekly intra-articular (i.a.) injections of 10, 30, and 100 µg o...
    Medical condition: Knee Cartilage Injury
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022117 - Injury, poisoning and procedural complications 10007710 Cartilage injury PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) HU (Completed) SI (Completed) BG (Prematurely Ended) AT (Completed)
    Trial results: View results
    EudraCT Number: 2009-010719-33 Sponsor Protocol Number: Gebro-III-48-4 Start Date*: 2009-05-27
    Sponsor Name:Gebro Pharma GmbH
    Full Title: Prospective, clinical trial to investigate safety, tolerability and efficacy of Dexibuprofen Gebro 400 mg powder for oral suspension (test) compared to Ibuprofen 400 mg powder for oral suspension (...
    Medical condition: Osteoarthritis of the hip or knee
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2012-001249-41 Sponsor Protocol Number: KEK-ZH-2012-0249 Start Date*: 2013-04-12
    Sponsor Name:University Hospital of Zurich and City Hospital Waid
    Full Title: Vitamin D3 – Omega3 – Home Exercise – HeALTHy Ageing and Longevity Trial Randomized, double-blind, placebo-controlled, multi-centre clinical trial
    Medical condition: healthy ageing, functional decline
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing) PT (Completed) FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-018187-10 Sponsor Protocol Number: DODO1011 Start Date*: 2010-04-21
    Sponsor Name:Ziekenhuisgroep Twente
    Full Title: Double dose treatment: Corticosteroid injection therapy in arthritis
    Medical condition: To determine whether doubling the dose of triamcinolone injections in the treatment of arthritis in knee joints is more effective, both in number of responding patients and in duration of response ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-000799-42 Sponsor Protocol Number: DIC 100-2004 Start Date*: 2005-07-13
    Sponsor Name:Mepha Ltd.
    Full Title: Randomised, double-blind, active-controlled, parallel-group, multicentre study comparing two slow release formulations of 100 mg diclofenac in patients with primary symptomatic osteoarthritis of th...
    Medical condition: Primary symptomatic osteoarthritis of the hip and/or knee
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-000784-16 Sponsor Protocol Number: NCPACI Start Date*: 2016-04-15
    Sponsor Name:Akershus University Hospital
    Full Title: Focal cartilage defects in the knee – A randomized controlled trial comparing Autologous Chondrocyte Implantation with arthroscopic debridement
    Medical condition: Symptomatic focal cartilage defects in the knee
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002670-36 Sponsor Protocol Number: OXN3503 Start Date*: 2009-01-30
    Sponsor Name:Mundipharma Research GmbH & Co. KG
    Full Title: A randomised, double-blind, double-dummy, parallel-group multicentre study to demonstrate non-inferiority in pain and locomotor function and improvement in symptoms of constipation in subjects with...
    Medical condition: Pain, locomotor function and improvement in constipation in osteoarthritis patients taking opioids
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031161 Osteoarthritis LLT
    9.1 10021175 Iatrogenic constipation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) CZ (Completed) HU (Completed) NL (Completed) ES (Completed) AT (Completed) FI (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2015-003408-21 Sponsor Protocol Number: THO-IM_02-CT Start Date*: 2015-12-09
    Sponsor Name:Thrombotargets Europe
    Full Title: A Phase II/III, randomized, controlled, single blind study to evaluate the haemostatic efficacy and safety of topically applied TT-173 in patients undergoing knee arthroplasty
    Medical condition: Haemostatic effect in patients undergoing knee arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004865 10060663 Surgical hemostasis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-003748-43 Sponsor Protocol Number: TKA 4 Start Date*: 2006-11-23
    Sponsor Name:Ortopædkirurgisk Center, Aarhus Universitets Hospital
    Full Title: Kan topical bisfosfonat øge fiksation og overlevelse af ucementeret knæledsprotese? Et prospektivt randomiseret migrations- og knogledensitetsstudie på tibia-implantater af trabeculært metal.
    Medical condition: Osteoarthritis of the knee treated with knee alloplastic
    Disease: Version SOC Term Classification Code Term Level
    8.1 10031200 Osteoarthrosis, localized, primary, involving lower leg LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-005082-31 Sponsor Protocol Number: MP-TAP-2016-01 Start Date*: 2017-11-20
    Sponsor Name:MRI Research Unit, Radiology Department. Hospital del Mar.
    Full Title: Assessment of Tapentadol effects on patients with pain central sensitization using functional MRI
    Medical condition: Patients suffering from pain due to knee osteoarthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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