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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,336 result(s) found. Displaying page 1,100 of 2,217.
    EudraCT Number: 2005-002983-27 Sponsor Protocol Number: PDT05 Start Date*: 2005-11-09
    Sponsor Name:Universitätsklinikum der RWTH Aachen - Ärztlicher Direktor Univ.-Prof. Dr. H. Sass
    Full Title: Prospektive randomisierte Studie zur Untersuchung der Wirksamkeit der Photodynamischen Therapie bei aktinischen Keratosen
    Medical condition: Aktinische Keratose
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2017-004655-23 Sponsor Protocol Number: CR4056-2-03 Start Date*: 2018-09-24
    Sponsor Name:Rottapharm Biotech s.r.l.
    Full Title: A randomized, double-blind, active- and placebo-controlled, parallel group, single dose, multicentre study to assess the analgesic effect of CR4056 in postoperative dental pain
    Medical condition: Postoperative dental pain
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10036276 Postoperative analgesia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2015-000748-41 Sponsor Protocol Number: 15/135763 Start Date*: 2015-09-03
    Sponsor Name:University of Exeter
    Full Title: Autoimmune Diabetes Accelerator Prevention Trial (adAPT)
    Medical condition: Children aged 5 to 16 on entry to the RCT with the presence of two or more islet-related autoantibodies which confers a 40% risk of developing type 1 diabetes in five years.
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004861 10036481 Pre-diabetes LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-003302-10 Sponsor Protocol Number: GELTAMO- Z-RIC - Allo Start Date*: 2007-11-14
    Sponsor Name:GELTAMO (Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea)
    Full Title: Trasplante alogénico de progenitores hematopoyéticos tras acondicionamiento no mieloablativo con melfalan ,fludarabina y zevalin en pacientes con linfoma No Hodgkin B agresivo
    Medical condition: Linfoma no Hodgkin de células B, CD20+, agresivo (linfoma difuso de células grandes, linfoma de células del manto, linfoma de células B transformado), de alto riesgo, con indicación de trasplante a...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2011-002571-42 Sponsor Protocol Number: 310409BS Start Date*: 2011-11-29
    Sponsor Name:GALENpharma GmbH
    Full Title: Phase IIa, multi-center, randomized, double-blind, vehicle-controlled study for assessment of clinical skin condition and effects on barrier impairment of a topical formulation containing tarenflur...
    Medical condition: Subjects with mild to moderate atopic eczema
    Disease: Version SOC Term Classification Code Term Level
    14.0 10040785 - Skin and subcutaneous tissue disorders 10003641 Atopic eczema LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2016-003684-19 Sponsor Protocol Number: 15-163 Start Date*: 2018-02-08
    Sponsor Name:RWTH Aachen, represented by the Rector, himself represented by the Dean of the Medical Faculty
    Full Title: Xenon-anesthesia on patients undergoing major liver-resection: randomized controlled trial
    Medical condition: post-resectional liver failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-012428-10 Sponsor Protocol Number: MBCT2009 Start Date*: 2009-11-06
    Sponsor Name:University of Exeter
    Full Title: Preventing depression relapse / recurrence in NHS settings through mindfulness-based cognitive therapy (MBCT).
    Medical condition: Recurrent depression. Patients who have experienced 3 or more episodes of depression and are already taking anti-depressants will be invited to take part in this study.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2014-000973-38 Sponsor Protocol Number: 14-026 Start Date*: 2014-05-14
    Sponsor Name:RWTH Aachen vertreten durch das CTC-A
    Full Title: Xenon-inhalation: elimination of xenon and its effect on erythropoetin-levels in blood of healthy volunteers
    Medical condition: Healthy volunteers
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-003859-12 Sponsor Protocol Number: 12-027 Start Date*: 2013-07-19
    Sponsor Name:RWTH Aachen University for the Medical Faculty, represented by Clinical Trial Center Aachen (CTC-A)
    Full Title: Linagliptin as a modulator of vascular inflammation in patients with type 2 diabetes mellitus
    Medical condition: patients with type 2 diabetes mellitus and vascular inflammation
    Disease: Version SOC Term Classification Code Term Level
    17.0 10018065 - General disorders and administration site conditions 10061218 Inflammation PT
    17.0 10027433 - Metabolism and nutrition disorders 10012601 Diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-002611-29 Sponsor Protocol Number: MEL001 Start Date*: 2012-04-04
    Sponsor Name:Freistaat Bayern
    Full Title: A prospective phase I and consecutive phase II, twoarm, randomized multi-center trial of temsirolimus in combination with pioglitazone, etoricoxib and metronomic low-dose trofosfamide versus dacarb...
    Medical condition: metastatic melanoma or metastatic uveal carcinoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-006016-33 Sponsor Protocol Number: E410/2007 Start Date*: 2008-09-30
    Sponsor Name:Uniklinikum Tuebingen
    Full Title: Multicenter Phase II study of haploidentical hematopoietic cell transplantation with CD3/CD19 depleted grafts after a reduced intensity conditioning regimen for adult patients with acute leukemia
    Medical condition: Patients with acute leukemia with an indication for allogeneic HCT but without a suitable HLA-identical donor
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-001994-66 Sponsor Protocol Number: ECIT-PRO19 Start Date*: 2020-05-06
    Sponsor Name:Fundació Assistencial Mútua Terrassa
    Full Title: Ramdomised clinical trial of ivermectin for treatment and prophylaxis of COVID-19
    Medical condition: SARS COVID-19
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-003946-34 Sponsor Protocol Number: OB-401 Start Date*: 2013-10-30
    Sponsor Name:VIVUS, Inc.
    Full Title: A Qsymia™ CardiovascuLAr morbIdity and Mortality (AQCLAIM) Study in Subjects with Documented Cardiovascular Disease
    Medical condition: Cardiovascular Disease in overweight and obese subjects
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004849 10007648 Cardiovascular disease, unspecified LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) CZ (Prematurely Ended) SK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-003526-32 Sponsor Protocol Number: EQI7-16-02 Start Date*: 2018-08-14
    Sponsor Name:Fidia Farmaceutici S.p.A.
    Full Title: Randomised, double blind, parallel-groups, non-inferiority versus Flector® and superiority versus Placebo, Phase III clinical trial with Diclofenac Sodium 140 mg medicated plaster in patients with ...
    Medical condition: Patients with painful and phlogistic (inflammatory response) disease due to acute traumatic events (injury/contusion) of the limbs
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) HU (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-020489-82 Sponsor Protocol Number: Q16-10-01 Start Date*: 2010-08-25
    Sponsor Name:Fidia Farmaceutici S.p.A.
    Full Title: Randomised, double-blind, placebo-controlled, parallel-groups, multi-centre clinical trial Phase III with Diclofenac Sodium 140 mg medicated plaster in patients with fresh impact injuries of the li...
    Medical condition: Fresh impact injuries of the limbs (Contusions, strains and sprains)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2014-000835-17 Sponsor Protocol Number: BRESHAP-GELTAMO.LH-2013 Start Date*: 2014-08-18
    Sponsor Name:GELTAMO (Grupo Cooperativo Español de Linfoma/Trasplante Autólogo de Médula Ósea)
    Full Title: PHASE I-II CLINICAL TRIAL FOR THE EVALUATION OF THE ROLE OF BRENTUXIMAB VEDOTIN PLUS ETOPOSIDE, SOLUMODERIN, HIGH DOSE ARA-C AND CIS-PLATIN IN THE TRANSPLANT AND POST-TRANSPLANT MANAGEMENT FOR PATI...
    Medical condition: CLASSICAL HODGKIN LYMPHOMA
    Disease: Version SOC Term Classification Code Term Level
    17.0 10005329 - Blood and lymphatic system disorders 10025319 Lymphomas Hodgkin's disease HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2012-005223-32 Sponsor Protocol Number: OMB116481 Start Date*: 2013-08-29
    Sponsor Name:Medizinische Universität Wien, Klinik für Innere Medizin I, Abt. Onkologie
    Full Title: A Phase II trial of Ofatumumab in patients with lymphoma of the of the mucosa associated lymphoid tissue (MALT-Lymphoma)
    Medical condition: LYMPHOMA OF THE MUCOSA ASSOCIATED LYMPHOID TISSUE (MALT-LYMPHOMA)
    Disease: Version SOC Term Classification Code Term Level
    16.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061850 Extranodal marginal zone B-cell lymphoma (MALT type) PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2015-003290-15 Sponsor Protocol Number: GTI1503 Start Date*: 2016-05-12
    Sponsor Name:Grifols Therapeutics Inc.
    Full Title: A Multi-Centre, Open-Label, Single Arm Trial to Evaluate Efficacy, Pharmacokinetics, and Safety and Tolerability of IGSC 20% in Subjects with Primary Immunodeficiency
    Medical condition: Primary Immunodeficiency (PI) diseases
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021428 - Immune system disorders 10061598 Immunodeficiency PT
    20.0 10021428 - Immune system disorders 10045792 Unspecified disorder of immune mechanism LLT
    20.0 10010331 - Congenital, familial and genetic disorders 10064859 Primary immunodeficiency syndrome PT
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) CZ (Completed) ES (Completed) DE (Completed) PL (Completed) HU (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2014-001834-27 Sponsor Protocol Number: GWEP1415 Start Date*: 2015-01-14
    Sponsor Name:GW Research Ltd
    Full Title: An open label extension study to investigate the safety of cannabidiol (GWP42003-P; CBD) in children and adults with inadequately controlled Dravet or Lennox-Gastaut Syndromes
    Medical condition: Dravet Syndrome (DS) or Lennox-Gastaut Syndrome (LGS)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10073677 Severe myoclonic epilepsy of infancy PT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed) ES (Completed) PL (Completed) NL (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2011-001010-34 Sponsor Protocol Number: G-LUCAS Start Date*: 2011-11-08
    Sponsor Name:ABCSG (Austrian Breast & Colorectal Cancer Study Group)
    Full Title: A randomized, placebo-controlled, double-blind multicenter phase II study to investigate the protectivity and efficacy of Metformin against steatosis in combination with FOLFIRI and Cetuximab in su...
    Medical condition: first-line palliative treated, KRAS-Wild-Type, metastatic colorectal cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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