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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44393   clinical trials with a EudraCT protocol, of which   7405   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,393 result(s) found. Displaying page 1,127 of 2,220.
    EudraCT Number: 2004-001467-22 Sponsor Protocol Number: A6181040 Start Date*: 2004-10-26
    Sponsor Name:Pfizer S.A.
    Full Title: A PHASE 2 EFFICACY AND SAFETY STUDY OF SU011248 IN PATIENTS WITH METASTATIC NON-SMALL CELL LUNG CANCER
    Medical condition: Histologically proven NSCLC (Stage IV or recurrent disease or locally advanced [Stage IIIB]) that is not amenable to surgery, radiation, or combined modality therapy with curative intent
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-001258-26 Sponsor Protocol Number: CVAH631B2406 E1 Start Date*: 2006-03-14
    Sponsor Name:Novartis Faarmacéutica S.A
    Full Title: Extensión de 8 semanas de duración del estudio multicéntrico, aleatorizado, doble ciego, de grupos paralelos, de control activo, de 14 semanas de duración para evaluar la efectividad de la estrateg...
    Medical condition: Essential hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) DK (Completed) GB (Completed) IE (Completed) IT (Completed) DE (Completed) FI (Completed)
    Trial results: View results
    EudraCT Number: 2005-002161-36 Sponsor Protocol Number: PM-C-0024 Start Date*: 2006-02-08
    Sponsor Name:Sanofi-Aventis Groupe
    Full Title: Randomized comparison of a two-month regimen of irbesartan versus enalapril on cardiovascular markers in patients with acute coronary syndrome without ST segment elevation.
    Medical condition: Acute coronary syndrome
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) HU (Completed) ES (Completed) IT (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-002256-17 Sponsor Protocol Number: 178-CL-044 Start Date*: 2006-01-19
    Sponsor Name:Astellas Pharma Europe B.V.
    Full Title: A Randomized, Double-blind, Parallel Group, Placebo and Active Controlled, Multi-Center Dose Ranging Study with the Beta-3 AGONist YM178 in Patients with Symptomatic Overactive Bladder (DRAGON)
    Medical condition: Overactive bladder
    Disease: Version SOC Term Classification Code Term Level
    8.1 10059617 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) CZ (Completed) DE (Completed) ES (Completed) SE (Completed) BE (Completed) HU (Completed) DK (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-002784-24 Sponsor Protocol Number: H3E-MC-JMHF Start Date*: 2005-04-26
    Sponsor Name:Eli Lilly and Company Limited
    Full Title: A Randomized, Double-Blind, Phase 2 Study of Two Doses of Pemetrexed in the Treatment of Platinum-Resistant, Epithelial Ovarian or Primary Peritoneal Cancer
    Medical condition: Femals with diagnosis of recurrent, epithelial ovarian or primary peritoneal cancer that is not amenable to curative therapy. Histologic confirmation of the original primary tumor is required. Pat...
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed) DE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2005-001463-64 Sponsor Protocol Number: CA183-001 Start Date*: 2005-07-14
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: A Phase II Study of Intravenous (IV) Vinflunine in Patients with Locally Advanced or Metastatic Transitional Cell Carcinoma (TCC) of the Urothelium Revised Protocol #01, version 2.0 incorporating ...
    Medical condition: Advanced Cancer, IV, Nos
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) ES (Completed) SE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-005210-37 Sponsor Protocol Number: WA18063 Start Date*: 2005-04-26
    Sponsor Name:F. Hoffmann La-Roche AG
    Full Title: A randomized, double-blind, placebo-controlled, parallel group study of the safety and reduction of signs and symptoms during treatment with MRA versus placebo, in combination with traditional DMAR...
    Medical condition: Rheumatoid Arthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DE (Completed) FI (Completed) CZ (Completed) ES (Completed)
    Trial results: Removed from public view
    EudraCT Number: 2006-000850-33 Sponsor Protocol Number: CVAA489A2403 Start Date*: 2006-07-20
    Sponsor Name:Novartis Pharma Services AG
    Full Title: An 8 week double-blind, randomized, multicenter, parallel group study to evaluate the efficacy and safety of orally administered valsartan/amlodipine combination based therapy versus amlodipine mon...
    Medical condition: Hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) BE (Completed) DK (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-000472-40 Sponsor Protocol Number: CN138-169 Start Date*: 2005-08-10
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: A Comparative, Randomized, Open -Label, Multicenter Study on the Efficacy and Safety of Switch Treatment with Aripiprazole in Schizophrenic Out-patients who are Experiencing Insufficient Efficacy w...
    Medical condition: Schizophrenia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed) HU (Completed) GB (Completed) AT (Completed) DE (Completed) CZ (Completed) BE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-005665-11 Sponsor Protocol Number: KMD3213-IT-CL 0215 Start Date*: 2006-03-23
    Sponsor Name:Recordati S.p.A
    Full Title: Evaluation Of The Efficacy And Safety Of Silodosin Vs. Tamsulosin And Placebo In The Treatment Of The Signs And Symptoms Of Benign Prostatic Hyperplasia. Multicentre, Randomised, Double-Blind, Cont...
    Medical condition: Benign prostatic hyperplasia (BPH) is a non malignant enlargement of the prostate due to cellular hyperplasia of both glandular and stromal elements. As the prostate increases in size it may exert ...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10004446 LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: FI (Completed) GB (Completed) IT (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2004-001258-94 Sponsor Protocol Number: A2171018 Start Date*: 2005-12-23
    Sponsor Name:Pfizer Pharma GmbH
    Full Title: One Year, Open-Label Outpatient, Parallel Group Trial Assessing the Impact of the Availability of Inhaled Insulin (Exubera®) on Glycemic Control in Patients with Type 2 Diabetes Mellitus Who Are Po...
    Medical condition: Type 2 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    7 10012601 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-004671-38 Sponsor Protocol Number: SYR-322-INS-011 Start Date*: 2006-04-05
    Sponsor Name:Takeda Global Research & Development Center, Inc.,
    Full Title: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Determine the Efficacy and Safety of SYR110322 (SYR-322) When Used in Combination with Insulin in Subjects with Type 2 Diabetes
    Medical condition: Type II diabetes mellitus.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) DE (Completed) ES (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2005-005225-54 Sponsor Protocol Number: 248.615 Start Date*: 2006-07-10
    Sponsor Name:Boehringer Ingelheim Pharma GmbH & Co. KG
    Full Title: A phase IV randomised, double-blind, placebo-controlled, dose titration trial with pramipexole (Sifrol®, Mirapexin®) 0.125-0.75 mg/day per os for 12 weeks to investigate the effects on RLS symptoms...
    Medical condition: Restless Legs Syndrome
    Disease: Version SOC Term Classification Code Term Level
    8.1 10058920 pref
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) IE (Completed) FI (Completed) DK (Completed) ES (Completed) IT (Completed) SE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-003827-10 Sponsor Protocol Number: APV102002 Start Date*: 2004-12-16
    Sponsor Name:GlaxoSmithKline, S.A.
    Full Title: A Phase III, Randomized, Controlled, Open-label, Multicentre, Three Arm Study to Compare the Efficacy and Safety of a Dual-boosted HIV-1 Protease Inhibitor (PI) regimen of Fosamprenavir (FPV)/ Lopi...
    Medical condition: Treatment of heavily pretreated patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) DE (Completed) IT (Prematurely Ended) GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-005141-19 Sponsor Protocol Number: ACT6355 Start Date*: 2006-04-03
    Sponsor Name:Sanofi-Synthelabo Recherche
    Full Title: Estudio aleatorizado de 12 semanas, multicéntrico, doble ciego, controlado con placebo, , de la eficacia y seguridad de comprimidos de AVE8134 1,0 mg en la disminución de A1c en el tratamiento de p...
    Medical condition: Diabetes Mellitus tipo 2.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) IT (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-001730-17 Sponsor Protocol Number: BAP00248/307 Start Date*: 2004-09-16
    Sponsor Name:Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
    Full Title: A Phase 3, Randomized Double-Blind Study of Ceftobiprole Medocaril Versus Linezolid Plus Ceftazidime in the Treatment of Nosocomial Pneumonia
    Medical condition: Nosocomial Pneumonia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052596 Nosocomial pneumonia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed) LV (Completed) HU (Completed) GB (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2004-000406-51 Sponsor Protocol Number: EMD20001 Start Date*: 2004-09-16
    Sponsor Name:GlaxoSmithKline
    Full Title: A Prospective, Randomized, Double-blind, Placebo Controlled, Dose Ranging, Multi-Center Study of the Safety and Efficacy of Three Days Continuous Intravenous Infusion of GR270773 in the Treatment o...
    Medical condition: Suspected or Confirmed Gram-negative Severe Sepsis in Adults
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) ES (Completed) CZ (Completed) LV (Completed) AT (Completed) HU (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2005-001475-35 Sponsor Protocol Number: 3098B1-201 Start Date*: 2006-03-23
    Sponsor Name:Wyeth Research Division of Wyeth Pharmaceuticals Inc., Clinical Research and Development
    Full Title: A 3-MONTH, RANDOMIZED, DOUBLE-BLIND, PLACEBO- CONTROLLED, MULTICENTER, SAFETY, TOLERABILITY, AND EFFICACY STUDY OF 3 DOSES OF LECOZOTAN (SRA-333) SR IN OUTPATIENTS WITH MILD TO MODERATE ALZHEIMER’...
    Medical condition: Alzheimer's Disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) FI (Completed) GB (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-002948-10 Sponsor Protocol Number: A0081007 Start Date*: 2005-07-14
    Sponsor Name:Pfizer AB
    Full Title: A Randomised Placebo-Controlled Trial of the Efficacy and Safety of Pregabalin in the Treatment of Subjects with Neuropathic Pain Associated with Lumbo-sacral Radiculopathy (protocol dates 2004-11...
    Medical condition: Pain associated with lumbo-sacral radiculopathy
    Disease: Version SOC Term Classification Code Term Level
    7.0 10050085 VTc
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DE (Completed) IT (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2006-002369-37 Sponsor Protocol Number: GID23 Start Date*: 2006-09-25
    Sponsor Name:Sanofi Pasteur SA
    Full Title: Lot-to-Lot Consistency Study of the Investigational, Split-virion, Inactivated Influenza Vaccine, Administered by the Intradermal Route in Adults.
    Medical condition: Vaccination of adults aged 18 to 60 years with inactivated, split-virion influenza vaccine administered by the intradermal route using Vaxigrip® as IM reference vaccine.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: LT (Completed) ES (Completed) GB (Completed)
    Trial results: View results
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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