Flag of the European Union EU Clinical Trials Register Help

Clinical trials for colon cancer

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44349   clinical trials with a EudraCT protocol, of which   7376   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    765 result(s) found for: colon cancer. Displaying page 12 of 39.
    EudraCT Number: 2011-002191-16 Sponsor Protocol Number: ML25153 Start Date*: 2011-07-22
    Sponsor Name:Medizinische Universität Wien, Univ.Klink f. Innere Medizin I
    Full Title: A Phase II pilot study to assess efficacy and safety of capecitabine and irinotecan plus bevacizumab followed by capecitabine and oxaliplatin plus bevacizumab or the reverse sequence in patients wi...
    Medical condition: Histologically or cytologically confirmed carcinoma of the colon and/or rectum with evidence of metastases. Diagnosis of metastatic disease according to RECIST not more than 3 months prior to e...
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004864 10010028 Colorectal cancer Duke's D LLT
    18.1 100000004864 10052362 Metastatic colorectal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2005-005846-37 Sponsor Protocol Number: ASL605LIOM02 XELOXIRI Start Date*: 2006-10-11
    Sponsor Name:G.O.N.O. Gruppo Oncologico del Nord Ovest
    Full Title: STUDY MULTICENTRIC PILOT OF CHEMOTHERAPY WITH CAPECITABINE, OXALIPLATIN LOHP IRINOTECAN Cpt-11 IN PATIENTS WITH Colorectal METASTATIC cancer
    Medical condition: Patients with metastatic colon-rectal cancer
    Disease: Version SOC Term Classification Code Term Level
    6.1 10052358 PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-002517-39 Sponsor Protocol Number: PRODIGE34 Start Date*: 2014-09-05
    Sponsor Name:Fédération Francophone de Cancérologie Digestive (FFCD)
    Full Title: Randomised phase III trial evaluating adjuvant chemotherapy after the stage III colon adenocarcinoma resection for patient of 70 year old or more
    Medical condition: Adjuvant treatment in stage III adenocarcinoma of the colon fully resected for patient of 70 years and over
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned) BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2006-006073-24 Sponsor Protocol Number: CCR2983 Start Date*: 2008-05-22
    Sponsor Name:Royal Marsden Hospital
    Full Title: CINATRA: Chromosomal Instability and Anti-Tubulin Response Assessment: A Phase II Study of Epothilone B in Metastatic Colon Carcinoma in patients with Microsatellite Instability or Chromosomal Inst...
    Medical condition: Metastatic or locally recurrent colorectal cancer in genetically unselected patients, followed by recruitment of patients selected for microsatellite positive tumours
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010035 Colorectal cancer stage IV LLT
    9.1 10010030 Colorectal cancer recurrent LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-015598-11 Sponsor Protocol Number: IGR2009/1539 Start Date*: 2010-03-12
    Sponsor Name:Institut Gustave Roussy
    Full Title: Essai de phase III multicentrique comparant la surveillance simple (standard) à la laparotomie exploratrice plus chimio-hyperthermie intrapéritonéale (CHIP), chez des patients atteints d’un cancer ...
    Medical condition: Cancers colorectaux à très haut risque de développer une carcinose péritonéale
    Disease: Version SOC Term Classification Code Term Level
    12.1 10068069 Peritoneal carcinomatosis LLT
    12.1 10061451 Colorectal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-001961-40 Sponsor Protocol Number: GI 0607 Start Date*: 2006-10-12
    Sponsor Name:Department of Oncology, University Hospital Herlev
    Full Title: Phase II study of therapy with Cetuximab and Irinotecan every second week to Irinotecan resistant patients with metastatic colorectal cancer-effect and biological markers
    Medical condition: In Denmark there is approximately 3600 new cases of Colorectal cancer every year. In Denmark about half of these patients will eventually develop metastatic disease. In Denmark it is suggested tha...
    Disease: Version SOC Term Classification Code Term Level
    9 10010029 1.0
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2013-001362-42 Sponsor Protocol Number: COI-B Start Date*: 2013-07-08
    Sponsor Name:Fondazione IRCCS Istituto Nazionale dei Tumori
    Full Title: Perioperative treatment with COI-B (Capecitabine, Oxaliplatin, Irinotecan and Bevacizumab) of high risk or borderline resectable colorectal liver metastases
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061451 Colorectal cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-002228-40 Sponsor Protocol Number: A3191193 Start Date*: 2006-08-28
    Sponsor Name:PFIZER
    Full Title: A PHASE III PLACEBO-CONTROLLED TRIAL OF CELECOXIB IN GENOTYPE POSITIVE SUBJECTS WITH FAMILIAL ADENOMATOUS POLYPOSIS
    Medical condition: FAMILIAL ADENOMATOUS POLYPOSIS (FAP)
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Prematurely Ended) SE (Completed) IT (Prematurely Ended) GB (Completed) CZ (Prematurely Ended) BE (Prematurely Ended) DE (Completed) HU (Prematurely Ended) SK (Completed) BG (Not Authorised)
    Trial results: View results
    EudraCT Number: 2012-000109-66 Sponsor Protocol Number: TPU-TAS-102-301 Start Date*: 2012-12-10
    Sponsor Name:Taiho Oncology, Inc.
    Full Title: RANDOMIZED, DOUBLE-BLIND, PHASE 3 STUDY OF TAS-102 PLUS BEST SUPPORTIVE CARE (BSC) VERSUS PLACEBO PLUS BSC IN PATIENTS WITH METASTATIC COLORECTAL CANCER REFRACTORY TO STANDARD CHEMOTHERAPIES
    Medical condition: Refractory metastatic colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    17.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10052358 Colorectal cancer metastatic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) SE (Completed) AT (Completed) ES (Completed) IE (Completed) CZ (Completed) BE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2021-005731-23 Sponsor Protocol Number: N21PMA Start Date*: 2022-10-25
    Sponsor Name:Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis
    Full Title: Pembrolizumab for locally advanced, irresectable, non-metastatic dMMR colorectal cancers. The PUMA study.
    Medical condition: adenocarcinoma of the colon or rectum
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061451 Colorectal cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-003158-24 Sponsor Protocol Number: Start Date*: 2011-09-22
    Sponsor Name:Pia Österlund and Helena Isoniemi
    Full Title: A population-based prospective study to evaluate clinical behaviour, resectability and survival in metastatic colorectal cancer patients in Finland
    Medical condition: Metastatic colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10052362 Metastatic colorectal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2004-004181-32 Sponsor Protocol Number: EMR 62202-636 Start Date*: 2004-12-07
    Sponsor Name:OSPEDALE ONCOLOGICO DI BARI
    Full Title: FOLFOX 4 + CETUXIMAB IN UNTREATED PATIENTS WITH ADVANCED COLO-RECTAL TUMOUR. A PHASE II MULTICENTER STUDY OF THE GRUPPO ONCOLOGICO DELL'ITALIA MERIDIONALE
    Medical condition: ADVANCED COLO-RECTAL TUMOUR
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010029 Colorectal cancer NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-001180-11 Sponsor Protocol Number: ML20514 Start Date*: 2009-03-16
    Sponsor Name:Roche Pharma AG
    Full Title: An Open-label, single-arm, Phase II study to evaluate the efficacy and the feasibility of bevacizumab (Avastin®) based on a FOLFOXIRI regimen until progression in patients with previously untreated...
    Medical condition: previously untreated metastatic colorectal carcinoma
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004864 10010036 Colorectal carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-004688-20 Sponsor Protocol Number: TTD-08-03 Start Date*: 2009-02-06
    Sponsor Name:Grupo de Tratamiento de los Tumores Digestivos (TTD)
    Full Title: Estudio de fase II con una combinación de Irinotecán, Capecitabina (Xeloda®) y Bevacizumab (Avastin®) en cáncer colorrectal metastático no pretratado
    Medical condition: Cáncer colorrectal metastásico no pretratado
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010029 Colorectal cancer NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2014-000845-64 Sponsor Protocol Number: CCR4085 Start Date*: 2014-12-17
    Sponsor Name:The Royal Marsden NHS Foundation Trust
    Full Title: A multicentre randomised phase II study of aflibercept plus chemotherapy in patients with colorectal liver-only metastases deemed to be inoperable or unsuitable for upfront liver resection
    Medical condition: colorectal cancer with liver metastases
    Disease: Version SOC Term Classification Code Term Level
    18.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061451 Colorectal cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-000333-71 Sponsor Protocol Number: Valentino Start Date*: 2015-06-19
    Sponsor Name:FONDAZIONE IRCCS "ISTITUTO NAZIONALE DEI TUMORI"
    Full Title: First-line FOLFOX-4 plus panitumumab followed by 5-FU/LV plus panitumumab or single-agent panitumumab as maintenance therapy in patients with RAS wild-type, metastatic colorectal cancer: the VALEN...
    Medical condition: Metastatic colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10001172 Adenocarcinoma of colon stage IV LLT
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10052360 Colorectal adenocarcinoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-004182-33 Sponsor Protocol Number: GemCap Start Date*: 2011-09-19
    Sponsor Name:Vejle Hospital
    Full Title: Phase II Study of gemcitabin and capecitabine in Chemotherapy Refractory Metastatic Colorectal Cancer
    Medical condition: Chemotherapy Refractory Metastatic Colorectal Cancer
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10052362 Metastatic colorectal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-006629-23 Sponsor Protocol Number: 61186372GIC2002 Start Date*: 2022-08-23
    Sponsor Name:Janssen-Cilag International NV
    Full Title: A Phase 1b/2, Open-Label Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants with Advanced or Metastatic Colorectal Cancer
    Medical condition: Advanced or Metastatic Colorectal Cancer
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061451 Colorectal cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned) ES (Ongoing) BE (Trial now transitioned) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2008-001355-21 Sponsor Protocol Number: 01-2008 Start Date*: 2008-06-30
    Sponsor Name:I.T.M.O. - ITALIAN TRIALS IN MEDICAL ONCOLOGY
    Full Title: First Line UFT, OXALIPLATIN and ERBITUX combination (TEGAFOX-E) in Elderly (≥ 70 years) metastatic colorectal patients: a Phase II ITMO study.
    Medical condition: Metastatic adenocarcinoma of colon or rectum
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052362 Metastatic colorectal cancer LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-002209-20 Sponsor Protocol Number: 2015/222/HP Start Date*: 2016-08-19
    Sponsor Name:CHU-Hôpitaux de Rouen
    Full Title: PRODIGE 50 - ASPIK : French prospective randomised double blind study on aspirin versus placebo in resected colon cancer with PI3K mutation stage III or II high risk
    Medical condition: Mutated PI3K colonic adenocarcinoma patients with surgical resection R0
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Fri Jul 18 07:04:31 CEST 2025 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA