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The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44381   clinical trials with a EudraCT protocol, of which   7393   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    39,307 result(s) found for: 1. Displaying page 1,204 of 1,966.
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    EudraCT Number: 2007-001179-13 Sponsor Protocol Number: 16891 Start Date*: 2008-01-24
    Sponsor Name:Dutch Cancer Society
    Full Title: Neo-adjuvant Simvastatin therapy in colorectal cancer
    Medical condition: Colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010023 Colorectal neoplasms malignant HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-001589-94 Sponsor Protocol Number: 2007-192 Start Date*: 2008-06-23
    Sponsor Name:Rigshospitalet
    Full Title: En randomiseret, placebo-kontrolleret, dobbelt-blind afprøvning af intravenøs immunglobulin til kvinder med uforklarlig sekundær abortus habitualis
    Medical condition: sekundær abortus habitualis defineret som 3 eller flere spontanaborter efter en fødsel og mindst 4 spontanaborter ialt.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10018807 Habitual aborter, currently pregnant, unspecified as to episode of care LLT
    Population Age: Adults Gender: Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-002741-23 Sponsor Protocol Number: BMH 001 Start Date*: 2008-08-22
    Sponsor Name:Berufsgenossenschaftliche Universitätsklinik Bergmannsheil GmbH
    Full Title: Intra-individual, randomized comparison of the MRI contrast agents Gadovist 1.0 versus Dotarem in imaging the distal lower limb of patients with known or suspicion of osteomyelitis, evaluated in a ...
    Medical condition: Osteomyelitis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031252 Osteomyelitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-005332-83 Sponsor Protocol Number: PAC Peg Adefovir Combination Start Date*: 2007-03-22
    Sponsor Name:AZIENDA OSPEDALIERA DI CASERTA
    Full Title: Combined therapy with Adefovir and Interferon-Pegylated alfa 2a vs Adefovir alone, in patients affected by chronic hepatitis B, HbeAg negative (The PAC (Peg Adefovir Combination) Study).
    Medical condition: Patients affected by chronic hepatitis B, HbeAg negative
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008910 Chronic hepatitis B LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-000782-35 Sponsor Protocol Number: 28-02 (ZKS000429) Start Date*: 2009-01-21
    Sponsor Name:Verein fuer Krebsfoschung (Society for Cancer Research)
    Full Title: Dose-escalating study to determine the maximum tolerated dose (MTD) of the mistletoe extract WEME 200 mg for intravesical instillation in patients with completely resected (R0) superficial bladder ...
    Medical condition: Patients after transurethral R0-resection (TUR) of a histologically confirmed superficial bladder carcinoma (pTa low grade [multilocular or recurrence], pT1 low grade); re-resections included.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10046518 Urinary bladder carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-002878-35 Sponsor Protocol Number: GAS study Start Date*: 2008-07-15
    Sponsor Name:ISTITUTO GIANNINA GASLINI
    Full Title: The GAS study. A multi-site RCT comparing regional and general anaesthesia for effects on neurodevelopmental outcome and apnoea in infants
    Medical condition: Inguinal Hernia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10022016 Inguinal hernia LLT
    Population Age: Preterm newborn infants, Newborns, Under 18 Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-005864-28 Sponsor Protocol Number: 130 Start Date*: 2008-05-30
    Sponsor Name:FONDAZIONE RICERCA TRAPIANTO DI MIDOLLO OSSEO
    Full Title: TREATMENT OF MINIMAL RESIDUAL DISEASE (MRD) IN ACUTE LEUKEMIA AFTER AN ALLOGENEIC STEM CELL TRANSPLANT
    Medical condition: Patients with acute leukemia and positive MRD post allogeneic hemopoietic stem cell transplant (HSCT)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000830 Acute leukaemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-005522-36 Sponsor Protocol Number: RD1 Start Date*: 2009-04-03
    Sponsor Name:RUH (Bath) NHS Trust
    Full Title: Chewing gum and orthodontic pain relief
    Medical condition: One of the most frequent side effects of orthodontic treatment with fixed braces is pain. This usually begins 2 to 3 hours after the fitting or adjustment of orthodontic appliances and may last up ...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050879 Orthodontic appliance wearer LLT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2009-011437-27 Sponsor Protocol Number: MAFRI Start Date*: 2009-10-27
    Sponsor Name:Fundació Clínic
    Full Title: EFECTO DE LA ADMINISTRACIÓN DE ALBÚMINA INTRAVENOSA Y MIDODRINA ORAL SOBRE LA FUNCIÓN RENAL DE LOS PACIENTES CON CIRROSIS HEPÁTICA Y INSUFICIENCIA RENAL FUNCIONAL
    Medical condition: mejorar la disfunción circulatória en pacientes con cirrosis hepática
    Disease: Version SOC Term Classification Code Term Level
    9 10009213 Cirrhosis of liver LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-012609-20 Sponsor Protocol Number: 343/09 Start Date*: 2009-09-08
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: INTRAVITREAL BEVACIZUMAB INJECTION VS. CONVENTIONAL LASER SURGERY FOR VISION-THREATENING RETINOPATHY OF PREMATURITY.
    Medical condition: AP-ROP
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038933 Retinopathy of prematurity LLT
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-012509-20 Sponsor Protocol Number: MERLOT Start Date*: 2009-07-28
    Sponsor Name:King's College Hospital NHS Foundation Trust
    Full Title: A randomised controlled trial of epimacular brachytherapy versus ranibizumab monotherapy for the treatment of subfoveal choroidal neovascularisation associated with wet age-related macular degenera...
    Medical condition: Wet age-related macular degeneration
    Disease: Version SOC Term Classification Code Term Level
    12.0 10067791 Wet macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-011238-84 Sponsor Protocol Number: CL3-20098-069 Start Date*: 2009-09-21
    Sponsor Name:Institut de Recherches Internationales Servier
    Full Title: Efficacy and safety of 3 dose regimens of agomelatine (10, 25, 25-50 mg) versus placebo given once a day for 6 weeks in out-patients suffering from moderate to severe Major Depressive Disorder. A 6...
    Medical condition: Major Depressive Disorder
    Disease: Version SOC Term Classification Code Term Level
    11.1 10057840 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SK (Completed) BG (Completed) FI (Completed)
    Trial results: View results
    EudraCT Number: 2009-014382-12 Sponsor Protocol Number: IRVASE. Start Date*: 2009-09-09
    Sponsor Name:Institut d'Anesthésiologie des Alpes Maritimes
    Full Title: ImpImpact du remplissage vasculaire par des solutés équilibrés sur la morbidité des patients de réanimation (IRVASE) : étude randomisée contrôlée monocentrique
    Medical condition: Patient de réanimation en état de choc
    Disease:
    Population Age: Gender:
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017139-16 Sponsor Protocol Number: Bay 86-5037/14853 Start Date*: 2010-06-10
    Sponsor Name:Bayer HealthCare AG
    Full Title: Effect of exercise alone or in combination with testosterone replacement on muscle strength and quality of life in older men with low testosterone concentrations: a randomized double-blind, placebo...
    Medical condition: The objective of this study is to determine whether in older men with symptomatic age-associated testosterone deficiency exercise training in combination with testosterone replacement therapy leads...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10021011 Hypogonadism male LLT
    Population Age: Elderly Gender: Male
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-016653-17 Sponsor Protocol Number: FARM73452X Start Date*: 2010-04-13
    Sponsor Name:AZIENDA UNITA` SANITARIA LOCALE N 12 DI VIAREGGIO
    Full Title: TREATMENT OF HYPOTENSION IN EXTREMELY PRETERM INFANTS: A MULTICENTER RANDOMIZED CONTROLLED TRIAL
    Medical condition: HYPOTENSION IN EXTREMELY PRETERM INFANTS
    Disease: Version SOC Term Classification Code Term Level
    9.1 10049223 LLT
    9.1 10049223 LLT
    9.1 10049223 LLT
    9.1 10049223 LLT
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-018108-17 Sponsor Protocol Number: PAC_2009 Start Date*: 2010-03-24
    Sponsor Name:Medizinische Universität Graz
    Full Title: Kann der antiaggregatorische Effekt von Clopidogrel und Acetylsalicylsäure durch die Gabe von Thrombozytenkonzentraten aufgehoben werden?
    Medical condition: Studie an gesunden Probanden. Zweck dieser Studie: Können autologe Thrombozyten-Konzentrate die Wirkung von Clopidogrel und Acetylsalicylsäure aufheben?
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: Removed from public view
    EudraCT Number: 2010-018324-13 Sponsor Protocol Number: CRLOT/01 Start Date*: 2011-11-09
    Sponsor Name:CONSORZIO PER LA RICERCA ONCOLOGICA
    Full Title: Open phase II randomized study to assess safety, tolerability and efficacy of trastuzumab combined with vinorelbine in patients with HER2 positive metastatic breast cancer and cardiac diseases
    Medical condition: HER2 positive breast cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038604 SOC
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-021207-25 Sponsor Protocol Number: CT327PV0109 Start Date*: 2010-08-23
    Sponsor Name:Creabilis Sàrl
    Full Title: CT 327 in the treatment of psoriasis vulgaris: A Randomized, Double-Blind, Placebo Controlled Phase II, Multi-Centre, Study of the Efficacy and Safety of CT 327, a topical cream formulation of Pegy...
    Medical condition: Psoriasis Vulgaris
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-014737-24 Sponsor Protocol Number: 68GaPET-HNSCC-2009 Start Date*: 2010-11-19
    Sponsor Name:Medizinische Universität Innsbruck
    Full Title: Vergleichende Studie zur Darstellung der Somatostatinrezeptoren bei Kopf-Hals-Tumoren mit Immunhistochemie und PET (68Ga-DOTA-Tyr3-Octreotid)
    Medical condition: Patients suffering from head and neck squamous cell carcinoma
    Disease: Version SOC Term Classification Code Term Level
    12.1 10067821 Head and neck cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-023606-13 Sponsor Protocol Number: LU01-2010 Start Date*: 2011-02-25
    Sponsor Name:GIENNE PHARMA S.P.A.
    Full Title: Efficacy and safety of Canrenone Add on in patients with Essential Hypertension
    Medical condition: HYPERTENSIVE PATIENTS NON ADEQUATELY CONTROLLED ON THERAPY WITH ACE-I OR ARB + DIURETIC
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015488 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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