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Clinical trials for Randomized Controlled Trial

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44338   clinical trials with a EudraCT protocol, of which   7368   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    5,636 result(s) found for: Randomized Controlled Trial. Displaying page 14 of 282.
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    EudraCT Number: 2019-002724-33 Sponsor Protocol Number: RECHMPL19-0069 Start Date*: 2019-11-15
    Sponsor Name:University Hospital of Montpellier
    Full Title: Eosinophil-driven corticotherapy for patients hospitalized for COPD exacerbation: a double-blind, randomized, controlled trial
    Medical condition: The study population corresponds to patients hospitalized for COPD exacerbation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-001041-20 Sponsor Protocol Number: F001AM0222_1 Start Date*: 2022-10-14
    Sponsor Name:University Hospital Wuerzburg
    Full Title: Prednisolone and vitamin B1, B6, and B12 in patients with Post-COVID-19-Syndrome (PC19S) – a randomized controlled trial in primary care
    Medical condition: Post-COVID-19-Syndrome (PC19S)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-002306-39 Sponsor Protocol Number: 156-03-236 Start Date*: 2005-07-15
    Sponsor Name:Otsuka Maryland Research Institute, Inc.
    Full Title: Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Long Term Efficacy and Safety of Oral Tolvaptan Tablets in Subjects Hospitalized with Worsening Congestive Heart Failure
    Medical condition: Subjects hospitalized with worsening congestive heart failure (CHF).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed)
    Trial results: View results
    EudraCT Number: 2008-005747-42 Sponsor Protocol Number: 1255/08 Start Date*: 2009-02-03
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Efficacy of a medical product containing sorbitol, simethicone and citrate potassium, in comparison with domperidone in patients affected by disfunctional dyspepsia: randomized monocentric cross-ov...
    Medical condition: dysfunctional dyspepsia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064536 Functional dyspepsia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-003201-81 Sponsor Protocol Number: GFVT01026904 (GACHE) Start Date*: 2006-12-20
    Sponsor Name:Universitätsklinikum Heidelberg
    Full Title: GACHE: German trial of Acyclovir and Corticosteroids in Herpes-simplex-virus-Encephalitis. A multicenter, multinational, randomized, double-blind, placebo-controlled German, Austrian and Dutch trial.
    Medical condition: Herpes simplex virus type-1 (HSV-1) is the most frequent cause of fatal sporadic encephalitis in humans. Herpes simplex encephalitis (HSE) was one of the first viral infections to be successfully t...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-006579-19 Sponsor Protocol Number: MP-EG-002 Start Date*: 2007-04-19
    Sponsor Name:Egalet a/s
    Full Title: A double-blind, randomized, 2-way cross-over, phase II, efficacy trial in cancer patients to assess the overall efficacy, patient preference, morphine related side effect profile and safety of the ...
    Medical condition: cancer patients
    Disease: Version SOC Term Classification Code Term Level
    8.1 10058019 Cancer pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-001810-18 Sponsor Protocol Number: 1503 Start Date*: 2007-09-06
    Sponsor Name:University Hospital Of North Staffordshire
    Full Title: Treatment of gastrostomy related granuloma using hydrocortisone or tea tree oil: A randomized controlled trial.
    Medical condition: Granulomas related to gastrostomy sites in children
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-016880-13 Sponsor Protocol Number: ITU version1 19/10/2009 Start Date*: 2011-03-11
    Sponsor Name:UNIVERSITY HOSPITALS OF LEICESTER NHS TRUST
    Full Title: RANDOMIZED CONTROLLED TRIAL OF THE EFFECTS OF PARENTERAL FISH OIL EMULSION IN CRITICALLY ILL SEPTIC PATIENTS IN THE INTENSIVE CARE UNIT
    Medical condition: Sepsis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-007932-25 Sponsor Protocol Number: 28091 Start Date*: 2008-05-07
    Sponsor Name:Merck Lipha Santé
    Full Title: A phase IIIb randomized open-label study to compare between IVF/ICSI outcomes two regimen of Cetrotide 0.25 mg used from Day 1 or from Day 7 of the menstrual cycle (Day 0 or Day 6 of stimulation) ...
    Medical condition: Prevention of premature ovulation in polycystic ovarian women undergoing a controlled ovarian stimulation, followed by oocyte pick-up and assisted reproductive techniques.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2018-001705-91 Sponsor Protocol Number: HEHDZ02 Start Date*: 2018-09-26
    Sponsor Name:Center for Perioperative Optimization, Department of Surgery, Herlev Hospital
    Full Title: MELADERM-trial: Melatonin cream against acute radiation dermatitis in patients with early breast cancer: a pivotal phase 2, double-blind, randomized, placebo-controlled trial
    Medical condition: Radiation dermatitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022117 - Injury, poisoning and procedural complications 10061103 Dermatitis radiation LLT
    20.1 10022117 - Injury, poisoning and procedural complications 10063562 Radiation skin injury PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2019-000203-33 Sponsor Protocol Number: 9119 Start Date*: 2019-10-16
    Sponsor Name:Klinisk Farmakologisk Afdeling
    Full Title: Paracetamol Discontinuation in the Elderly after long-term consumption (PARADISE)
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004867 10049475 Chronic pain LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-001683-22 Sponsor Protocol Number: 1/2011AITT Start Date*: 2011-06-10
    Sponsor Name:University of Debrecen, Medical and Health Science Center, Department of Anaesthesiology and Intensive Therapy
    Full Title: Reversal of residual rocuronium neuromuscular block using sugammadex: a prospective, dobule-blind, randomized, controlled, dose-finding study
    Medical condition: The effect of sugammadex dose on residual neuromuscular blockade will be investigated, therefore patients suffering from various conditions undergoing surgery in general anaesthesia with muscle rel...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-004666-34 Sponsor Protocol Number: AITT2014/1 Start Date*: 2014-03-17
    Sponsor Name:University of Debrecen, Medical and Health Science Center, Department of Anaesthesiology and Intensive Therapy
    Full Title: Reversal of vecuronium induced residual neuromuscular block using sugammadex: a prospective, dobule-blind, randomized, controlled, dosefinding study
    Medical condition: The effect of sugammadex dose on residual neuromuscular blockade will be investigated, therefore patients suffering from various conditions undergoing surgery in general anaesthesia with muscle rel...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-004789-24 Sponsor Protocol Number: PA21-T50-CKD5D-2016 Start Date*: 2017-03-10
    Sponsor Name:Ordensklinikum Linz, Krankenhaus der Elisabethinen Linz GmbH, III. Interne
    Full Title: The Effect of Phosphate Lowering using sucroferric oxyhydroxide (PA21) on Calcification Propensity of Serum – a randomized, controlled, open-label, cross-over trial
    Medical condition: end stage renal disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-003670-14 Sponsor Protocol Number: NA Start Date*: 2018-01-11
    Sponsor Name:University Hospital Limerick
    Full Title: The role of selective decontamination of the digestive tract in preventing surgical site infections in elective colorectal resections: a randomized controlled trial (SELDDEC Trial)
    Medical condition: Surgical Site Infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2015-000972-88 Sponsor Protocol Number: MK3475-062 Start Date*: 2015-08-20
    Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co.,
    Full Title: A Randomized, Active-Controlled, Partially Blinded, Biomarker Select, Phase III Clinical Trial of Pembrolizumab as Monotherapy and in Combination with Cisplatin+5-Fluorouracil versus Placebo+Cispla...
    Medical condition: Gastric or Gastroesophageal Junction Adenocarcinoma
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10030137 Oesophageal adenocarcinoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed) DE (Completed) LV (Completed) NL (Completed) ES (Completed) CZ (Completed) FR (Completed) AT (Completed) HU (Completed) BE (Completed) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2020-002035-30 Sponsor Protocol Number: TOFACOV-2 Start Date*: 2020-05-15
    Sponsor Name:AZIENDA OSPEDALIERO-UNIVERSITARIA OSPEDALI RIUNITI DI ANCONA
    Full Title: TOFAcitinib plus Hydroxycloroquine vs Hydroxycloroquine in patients with early onset SARS-CoV2 (COVID-19) interstitial pneumonia: a multicenter randomized controlled open label trial
    Medical condition: SARS-CoV2 related Interstitial Pneumonia
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10076502 Viral pneumonitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-000205-21 Sponsor Protocol Number: CCJM112X2204 Start Date*: 2018-01-29
    Sponsor Name:Novartis Pharma AG
    Full Title: A randomized, subject- and investigator-blinded, placebo-controlled, multi-center, multiple dose study to assess the efficacy and safety of CJM112 in patients with inadequately controlled moderate ...
    Medical condition: Inadequately controlled moderate to severe asthma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10003553 Asthma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) DK (Completed) BE (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2018-004567-31 Sponsor Protocol Number: XL184–313 Start Date*: 2019-09-04
    Sponsor Name:Exelixis, Inc.
    Full Title: A Randomized, Double-Blind, Controlled Phase 3 Study of Cabozantinib in Combination with Nivolumab and Ipilimumab versus Nivolumab and Ipilimumab in Subjects with Previously Untreated Advanced or M...
    Medical condition: Metastatic Renal Cell Carcinoma
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004864 10050076 Metastatic renal carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) FR (Trial now transitioned) DE (Trial now transitioned) ES (Ongoing) HU (Completed) BE (Trial now transitioned) FI (Trial now transitioned) NL (Trial now transitioned) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2005-004448-30 Sponsor Protocol Number: BT0700-204-GER Start Date*: 2006-03-13
    Sponsor Name:Barrier Therapeutics nv
    Full Title: A double-blind, placebo-controlled, randomized, multicenter, parallel-group phase IIa trial to assess the efficacy, safety and tolerability of topical 0.35% R115866 gel applied during 12 consecutiv...
    Medical condition: Mild to moderate acne vulgaris
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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