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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44351   clinical trials with a EudraCT protocol, of which   7378   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,351 result(s) found. Displaying page 199 of 2,218.
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    EudraCT Number: 2009-014854-14 Sponsor Protocol Number: CRFB002AGB10 Start Date*: 2009-11-17
    Sponsor Name:Novartis Pharmaceuticals UK Ltd
    Full Title: A phase II, open-label, multicentre, 12 month study to evaluate the efficacy and safety of ranibizumab (0.5 mg) in patients with choroidal neovascularization secondary to pathological myopia (PM)
    Medical condition: Choroidal neovascularisation (CNV) secondary to pathological myopia (PM)
    Disease: Version SOC Term Classification Code Term Level
    13.1 10015919 - Eye disorders 10060823 Choroidal neovascularisation PT
    13.1 10015919 - Eye disorders 10067128 Myopic retinal degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-014869-43 Sponsor Protocol Number: 2008_47/0928 Start Date*: 2009-12-21
    Sponsor Name:Centre Hospitalier Régional et Universitaire
    Full Title: Influence des acides gras polyinsaturés à longue chaîne n-3 sur l'expression des mucines dans la muqueuse nasale de patients atteints de mucoviscidose
    Medical condition: Mucoviscidose
    Disease: Version SOC Term Classification Code Term Level
    12.0 10028141 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-002758-31 Sponsor Protocol Number: ECD01 Start Date*: 2006-12-22
    Sponsor Name:EPOPLUS GmbH & Co.KG
    Full Title: A randomized, double-blind, multi-centre, placebo-controlled, parallel-group study to examine the efficacy and safety of low dose Epoetin beta on wound healing in diabetes patients with foot ulcer
    Medical condition: wound healing in diabetes patients with foot ulcer
    Disease: Version SOC Term Classification Code Term Level
    8.1 10048037 Wound healing disturbance of LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) BG (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-012222-36 Sponsor Protocol Number: 1.0 Start Date*: 2009-07-23
    Sponsor Name:Medizinische Universität Wien, Bernhard Gottlieb Universitätszahnklinik
    Full Title: Verification of an oro-antral communication after tooth extraction in the upper jaw. A Pilot-study
    Medical condition:
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-012226-37 Sponsor Protocol Number: PIOMET-55 Start Date*: 2010-01-15
    Sponsor Name:HOSPITAL SANT JOAN DE DÉU
    Full Title: Ensayo clínico piloto de tratamiento con Pioglitazona+Flutamida+Metformina a Dosis Bajas versus Etinil-Estradiol + Acetato de Ciproterona como control, en Adolescentes con Hiperandrogenismo Ovárico...
    Medical condition: Hiperandrogenismo ovárico asociado a hiperinsulinismo.
    Disease:
    Population Age: Adolescents, Under 18 Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-018919-16 Sponsor Protocol Number: TG-MV-010 Start Date*: 2010-06-28
    Sponsor Name:ThromboGenics NV
    Full Title: An Open-Label, Ascending- Exposure-Time, Single Center Trial to Evaluate the Pharmacokinetic Properties of Ocriplasmin (Generic Name of the Molecule Microplasmin) Intravitreal Injection in Subjects...
    Medical condition: Patients who require primary pars plana vitrectomy. A sample of vitreous will be taken at beginning of surgery for PK analysis.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10047644 Vitrectomy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2010-018937-23 Sponsor Protocol Number: SD-QVAR Start Date*: 2010-05-31
    Sponsor Name:Medisch Spectrum Twente
    Full Title: The predictive value of the acute effect of beclomethasone on a mannitol challenge test for the outcome of lomgterm treatment with beclomethasone
    Medical condition: Exercise induced asthma / bronchoconstriction Asthma
    Disease: Version SOC Term Classification Code Term Level
    12.1 10015649 Exercise induced asthma LLT
    12.1 10003553 Asthma PT
    12.1 10066091 Bronchial hyperreactivity PT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-007115-87 Sponsor Protocol Number: LH-HCGPES Start Date*: 2008-02-08
    Sponsor Name:FUNDACION CV INVESTIGACION HOSPITAL DR PESET
    Full Title: ENSAYO CLÍNICO UNICÉNTRICO PARA VALORAR LA EFICACIA DE LA ADMINISTRACIÓN EXÓGENA DE LH EN FORMA DE HCG EN EL TRATAMIENTO DE LA DISFUNCIÓN SEXUAL FEMENINA POR DISMINUCIÓN DEL DESEO SEXUAL
    Medical condition: DISMINUCIÓN DEL DESEO SEXUAL FEMENINO EN MUJERES MENOPÁUSICAS
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-007139-26 Sponsor Protocol Number: S075LBH501 Start Date*: 2008-04-17
    Sponsor Name:SENDO TECH
    Full Title: A phase II study of the histone deacetylase inhibitor Panobinostat (LBH589) in patients with advanced Small Cell Lung Cancer (SCLC)
    Medical condition: SCLC patients
    Disease: Version SOC Term Classification Code Term Level
    9.1 10041070 Small cell lung cancer recurrent LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) DE (Completed) GR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-016000-22 Sponsor Protocol Number: XM22-04 Start Date*: 2010-03-22
    Sponsor Name:BioGeneriX AG
    Full Title: Efficacy and safety of XM22 in patients with non small cell lung cancer receiving cisplatin / etoposide chemotherapy. A multinational, multicentre, randomised, double-blind placebo-controlled study
    Medical condition: Non Small Cell Lung Cancer
    Disease: Version SOC Term Classification Code Term Level
    12.0 10025054 Lung cancer non-small cell stage IIIB LLT
    12.0 10025055 Lung cancer non-small cell stage IV LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Completed)
    Trial results: View results
    EudraCT Number: 2010-020026-17 Sponsor Protocol Number: 721001 Start Date*: 2010-08-23
    Sponsor Name:Baxter Innovations GmbH
    Full Title: AN OPEN-LABEL PHASE 3 STUDY TO ASSESS THE IMMUNOGENICITY AND SAFETY OF A VERO CELL-DERIVED TRIVALENT SEASONAL INFLUENZA VACCINE, STRAIN COMPOSITION 2010/2011, IN AN ADULT AND ELDERLY POPULATION
    Medical condition: To verify the immunogenicity and tolerance of a trivalent seasonal influenza vaccine with strain composition according to WHO/EU recommendation for the 2010/2011 season for yearly licensing applica...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10022000 Influenza LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2010-023981-27 Sponsor Protocol Number: Acti-SCIPE-001 Start Date*: 2011-03-08
    Sponsor Name:Activaero GmbH
    Full Title: An Open-Label Randomized Pilot Trial to Evaluate Tolerability, Safety and Applicability of AKITA Inhaled Budesonide Suspension in Children aged 3-11 years with Mild to Moderate Asthma
    Medical condition: Allergic or non-allergic mild to moderate asthma in children aged three to eleven years. Affected children need to suffer from mild to moderate asthma according to ATS definition at least for 6 mon...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10003561 Asthma, unspecified LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-023987-41 Sponsor Protocol Number: 2010.2611 Start Date*: 2011-06-24
    Sponsor Name:University Medical Center Groningen
    Full Title: In vivo imaging of the effect of fulvestrant on availability of estrogen receptor binding sites in metastatic breast tumor lesions using [18F]FES-PET
    Medical condition: Estrogen Receptor-positive metastatic breast cancer patients that will be treated with fulvestrant
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-024013-31 Sponsor Protocol Number: CBPS804A2202 Start Date*: 2011-06-30
    Sponsor Name:Novartis Pharma Services AG
    Full Title: An open-label, intra-patient dose-escalation study to evaluate the safety and tolerability, pharmacokinetics, pharmacodynamics and preliminary efficacy of multiple infusions of BPS804 in adults wit...
    Medical condition: Hypophosphatasia (HPP) is a rare genetic metabolic disorder which results in impaired skeletal mineralization, and which is caused by the absence of or by deficient enzymatic activity of the tissue...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10010331 - Congenital, familial and genetic disorders 10049933 Hypophosphatasia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-012057-38 Sponsor Protocol Number: CQTI571A2301 Start Date*: 2009-08-13
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A 24-week randomized placebo-controlled, double-blind multi-center clinical trial evaluating the efficacy and safety of oral QTI571 as an add-on therapy in the treatment of severe pulmonary arteria...
    Medical condition: Pulmonary arterial hypertension (PAH) patients who have a PVR ≥800 dynes.sec.cm-5 despite treatment with two or more specific PAH therapies
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064911 Pulmonary arterial hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) ES (Completed) FR (Completed) SE (Completed) BE (Completed) IT (Completed) NL (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-012076-26 Sponsor Protocol Number: 20080560 Start Date*: 2009-10-01
    Sponsor Name:Amgen Inc
    Full Title: A Double-blind, Placebo-controlled Study to Evaluate New or Worsening Lens Opacifications in Subjects with Non-metastatic Prostate Cancer Receiving Denosumab for Bone Loss due to Androgen-Deprivati...
    Medical condition: Bone Loss in Subjects Undergoing Androgen-Deprivation Therapy (ADT) for Non-metastatic Prostate Cancer
    Disease: Version SOC Term Classification Code Term Level
    12.0 10065687 Bone loss LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: FR (Completed) CZ (Completed) PL (Completed) LV (Completed) GR (Completed) SK (Completed) BG (Completed) HU (Completed) SI (Completed)
    Trial results: View results
    EudraCT Number: 2005-005087-93 Sponsor Protocol Number: Start Date*: 2006-11-17
    Sponsor Name:East Kent Hospitals NHS Trust
    Full Title: A randomized double blind placebo controlled trial of Memantine in the treatment of Agitation in Alzheimers Dementia
    Medical condition: Alzheimers dementia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-013780-19 Sponsor Protocol Number: CRAD001AES07 Start Date*: 2010-02-18
    Sponsor Name:NOVARTIS FARMACÉUTICA S.A
    Full Title: Estudio multicéntrico, aleatorizado, abierto, de 24 meses de duración, con dos grupos paralelos, para comparar la eficacia de everolimus en la mejora del perfil cardiovascular en el régimen con AMF...
    Medical condition: Demostrar que el tratamiento inmunosupresor con everolimus (Certican®) tiene un impacto positivo en la enfermedad cardiovascular, una de las principales causas de morbilidad y mortalidad en los pac...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2009-013792-22 Sponsor Protocol Number: LEO 29102-C21 Start Date*: Information not available in EudraCT
    Sponsor Name:LEO Pharma A/S
    Full Title: A Phase 2, proof of concept and dose finding study, investigating treatment efficacy of LEO 29102 cream (2.5 mg/g, 1.0 mg/g, 0.3 mg/g, 0.1 mg/g, 0.03 mg/g), LEO 29102 cream vehicle, and Elidel (Pim...
    Medical condition: Diagnosis of atopic dermatitis graded as mild to moderate according to the Rajka and Langeland system.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10003639 Atopic dermatitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) FI (Completed)
    Trial results: View results
    EudraCT Number: 2011-000213-39 Sponsor Protocol Number: 102210 Start Date*: 2011-06-27
    Sponsor Name:Erasmus MC
    Full Title: Intramuscular corticosteroid injections in hip osteoarthritis: a double-blinded randomized controlled trial
    Medical condition: Hip osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    12.1 10018407 Glucocorticoids normal LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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