Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Apomorphine

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44352   clinical trials with a EudraCT protocol, of which   7379   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    41 result(s) found for: Apomorphine. Displaying page 2 of 3.
    « Previous 1  2  3  Next»
    EudraCT Number: 2006-004582-33 Sponsor Protocol Number: VR040/2/002 Start Date*: 2006-11-03
    Sponsor Name:Vectura Group plc
    Full Title: A Randomised, Double-Blind, Placebo-Controlled, Parallel-Group, Dose-Escalating Study Investigating the Efficacy and Safety of VR040 in the Treatment of Unpredictable “Off” or End-of-Dose “Wearing ...
    Medical condition: Hypomobility (off or freezing) episodes associated with advanced Parkinson's disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-005476-32 Sponsor Protocol Number: VR004/008 Start Date*: 2006-02-02
    Sponsor Name:Vectura Group plc
    Full Title: A Phase IIb, Randomised, Double-Blind, Placebo Controlled, Dose Finding Study Assessing the Haemodynamic Safety and "At Home" Efficacy of Inhaled VR004 in patients with Erectile Dysfunction (ED).
    Medical condition: Erectile dysfunction
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-005814-31 Sponsor Protocol Number: ND0612H-012 Start Date*: 2016-08-29
    Sponsor Name:NeuroDerm Ltd.
    Full Title: A multicenter, international, open-label, safety study of ND0612, a solution of levodopa/carbidopa delivered via a pump system as a continuous subcutaneous infusion in subjects with advanced Parkin...
    Medical condition: Subjects with advanced Parkinson's disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10061536 Parkinson's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Trial now transitioned) DE (Ongoing) FR (Trial now transitioned) CZ (Completed) PL (Trial now transitioned) HU (Prematurely Ended) ES (Completed) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2005-000431-22 Sponsor Protocol Number: CLLLN Start Date*: 2005-03-10
    Sponsor Name:AZIENDA SANITARIA OSPEDALIERA "S. GIOVANNI BATTISTA DI TORINO"
    Full Title: VALUTATION OF PLACEBO EFFECT AFTER CONDITIONING WITH APOMORPHINE AND WITHOUT PHARMACOLOGICAL CONDITIONING ON THE RIGIDITY AND ELECTRICAL ACTIVITY OF NEURONS OF SUBTHALAMIC NUCLEUS IN PARKINSON PATI...
    Medical condition: THE TOPICAL INVESTIGATION IS THE BASE OF PATOLOGY
    Disease: Version SOC Term Classification Code Term Level
    6.1 10061536 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-002321-23 Sponsor Protocol Number: V1ComplexitDOC Start Date*: 2022-03-21
    Sponsor Name:University of Liège
    Full Title: Complexity-enhancing drugs to treat disorders of consciousness (DoC): a ketamine study
    Medical condition: Disorders of consciousness as Unresponsive Wakefulness Syndrome (UWS) and Minimally Conscious State (MCS) after a coma due to acquired brain injury. Patients who emerged from the minimally consciou...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2021-006486-38 Sponsor Protocol Number: ComplexitDOC_PSI Start Date*: 2022-08-17
    Sponsor Name:University of Liege
    Full Title: Complexity-enhancing drugs to treat disorders of consciousness (DoC): a psilocybin study
    Medical condition: Disorders of consciousness as unresponsive wakefulness syndrome (UWS) and minimally conscious state (MCS) after a coma due to acquired brain injury.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-003458-18 Sponsor Protocol Number: IRL790C003 Start Date*: 2017-12-19
    Sponsor Name:Integrative Research Laboratories AB (IRLAB)
    Full Title: A randomised, double-blind, placebo-controlled, phase IIA study evaluating the efficacy and tolerability of IRL790 in Parkinson's disease dyskinesia
    Medical condition: Parkinson's disease dyskinesia
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10061536 Parkinson's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) SE (Completed)
    Trial results: View results
    EudraCT Number: 2012-000181-37 Sponsor Protocol Number: CVT-301-002 Start Date*: 2012-04-25
    Sponsor Name:Civitas Therapeutics, Inc.
    Full Title: A Randomized, Placebo-Controlled Phase 2 Study of the Safety, Pharmacokinetics, and Pharmacodynamics of CVT-301 (Levodopa Inhalation Powder) in Patients with Parkinson’s Disease and Motor Response ...
    Medical condition: Parkinson's Disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10034007 Parkinson's disease NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-005078-39 Sponsor Protocol Number: ND0612H-006 Start Date*: 2016-09-21
    Sponsor Name:NeuroDerm Ltd.
    Full Title: A multicenter, parallel-group, rater-blinded, randomized clinical study investigating the efficacy, safety, tolerability and pharmacokinetics of 2 dosing regimens of ND0612H, a solution of levodopa...
    Medical condition: Subjects with advanced Parkinson's disease
    Disease: Version SOC Term Classification Code Term Level
    18.1 10029205 - Nervous system disorders 10061536 Parkinson's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) AT (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-005822-31 Sponsor Protocol Number: CVT-301-003 Start Date*: 2013-04-18
    Sponsor Name:Civitas Therapeutics, Inc.
    Full Title: A Phase 2b, Randomized, Double-blind, Placebo-controlled Study Investigating the Efficacy and Safety of Inhaled CVT 301 (Levodopa Inhalation Powder) in Parkinson’s Disease Patients With Motor Respo...
    Medical condition: Parkinson's Disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004852 10034007 Parkinson's disease NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-004464-69 Sponsor Protocol Number: VR004/003 Start Date*: 2005-03-22
    Sponsor Name:vectura group plc
    Full Title: A Home Based Phase IIb, Multi-centre, Randomised, Double-Blind, Placebo Controlled, Dose Finding Parallel Group Study to explore the Optimal Dose of Inhaled VR004 in Patients with Erectile Dysfunct...
    Medical condition: erectile dysfunction
    Disease: Version SOC Term Classification Code Term Level
    10052003
    Population Age: Adults Gender: Male
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2020-002010-41 Sponsor Protocol Number: IRL790C005 Start Date*: 2020-12-22
    Sponsor Name:Integrative Research Laboratories Sweden AB (IRLAB)
    Full Title: A randomized, double-blind, placebo-controlled phase IIB study evaluating the efficacy of mesdopetam on DAILY on-time without troublesome dyskinesia in patients with Parkinson’s disease
    Medical condition: Parkinson's disease dyskinesia
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10061536 Parkinson's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-018650-12 Sponsor Protocol Number: 0930303 Start Date*: 2010-07-13
    Sponsor Name:CHU de Toulouse
    Full Title: Evaluation du système noradrénergique dans l’altération de la perception douloureuse chez le patient Parkinsonien
    Medical condition: maladie de Parkinson
    Disease: Version SOC Term Classification Code Term Level
    12.1 10013113 Disease Parkinson's LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-001651-31 Sponsor Protocol Number: 1.0 Start Date*: 2017-11-30
    Sponsor Name:Newcastle upon Tyne Hospitals NHS Foundation Trust
    Full Title: EMPOWER: EMesis in Pregnancy - Ondansetron With mEtoclopRamide.
    Medical condition: Nausea and Vomiting in pregnancy Hyperemesis gravidarum
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-012897-12 Sponsor Protocol Number: BIA-91067-202 Start Date*: 2009-12-08
    Sponsor Name:BIAL-Portela & Ca, SA
    Full Title: A double-blind, randomised, placebo-controlled study to investigate the tolerability and the effect of three multiple-dose regimens of BIA 9-1067 on the levodopa pharmacokinetics, catechol-0-methyl...
    Medical condition: Parkinson’s Disease
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004852 10013113 Disease Parkinson's LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: RO (Completed)
    Trial results: View results
    EudraCT Number: 2008-003869-72 Sponsor Protocol Number: BIA-91067-201 Start Date*: 2008-10-03
    Sponsor Name:Bial - Portela & Cª, S.A.
    Full Title: A DOUBLE-BLIND, RANDOMISED, PLACEBO-CONTROLLED, CROSS-OVER STUDY TO INVESTIGATE THE TOLERABILITY AND EFFECT OF THREE SINGLE-DOSE REGIMENS OF BIA 9-1067 ON THE LEVODOPA PHARMACOKINETICS, MOTOR RESPO...
    Medical condition: Parkinson
    Disease: Version SOC Term Classification Code Term Level
    9.1 10013113 Disease Parkinson's LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PT (Completed)
    Trial results: View results
    EudraCT Number: 2009-018137-37 Sponsor Protocol Number: 09/0391 Start Date*: 2010-04-14
    Sponsor Name:University College London
    Full Title: An open label, single site, 12 month, Phase II, randomised controlled trial evaluating the safety and efficacy of Exendin-4 (Exenatide) in the treatment of patients with moderate severity Parkinson...
    Medical condition: Parkinson's disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10061536 Parkinson's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-000135-14 Sponsor Protocol Number: PXT-CL17-001 Start Date*: 2017-05-26
    Sponsor Name:Prexton Therapeutics B.V.
    Full Title: A Multi-centre, Double-blind, Randomised, Placebo-controlled, Parallel-arm Phase IIa Trial to Evaluate the Efficacy, Safety and Tolerability of 28-Day Oral Treatment with PXT002331 (foliglurax) in ...
    Medical condition: Parkinson’s Disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10061536 Parkinson's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) DE (Completed) GB (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2008-008712-98 Sponsor Protocol Number: CAFQ056A2208 Start Date*: 2009-05-18
    Sponsor Name:Novartis Pharma AG
    Full Title: 13-week, double-blind, placebo-controlled, fixed-dose, multicenter study to evaluate the efficacy and safety of AFQ056 in reducing moderate to severe L-dopa induced dyskinesias in patients with Par...
    Medical condition: moderate to severe levodopa induced dyskinesias in patients with Parkinson's disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10013916 Dyskinesia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) ES (Completed) FR (Completed) IT (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-001929-20 Sponsor Protocol Number: TEST-APO Start Date*: 2010-05-18
    Sponsor Name:Servicio de Psiquiatría. Hospital Universitari Vall d’Hebron
    Full Title: EL TEST DE APOMORFINA COMO MARCADOR BIOLÓGICO DE LAS RECAÍDAS EN PACIENTES DEPENDIENTES DE SUSTANCIAS PSICOTROPAS
    Medical condition: Dependencia de alcohol Dependencia de cocaína Dependencia de heroína
    Disease: Version SOC Term Classification Code Term Level
    9 10001590 Alcohol addiction LLT
    9 10009815 Cocaine addiction LLT
    9 10019935 Heroin addiction LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    « Previous 1  2  3  Next»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Sat Aug 02 10:07:40 CEST 2025 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA