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Clinical trials for Clinical Management

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    1,653 result(s) found for: Clinical Management. Displaying page 2 of 83.
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    EudraCT Number: 2007-002080-27 Sponsor Protocol Number: KPS 2008-01 Start Date*: 2008-08-06
    Sponsor Name:Greater Glasgow Health Board/University of Glasgow
    Full Title: A randomised, double-blind controlled trial of ketamine versus placebo in conjunction with best pain management in neuropathic pain in cancer patients
    Medical condition: Patients who have neuropathic pain related to cancer and/or treatment for cancer (surgical, chemotherapy or radiotherapy) which has resulted in neuropathic pain.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10059513 Palliative care LLT
    3.0 10033470 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2021-005272-19 Sponsor Protocol Number: 20190184 Start Date*: 2023-01-08
    Sponsor Name:Amgen Inc
    Full Title: EVOLVE-MI: A Pragmatic Randomized Multicenter Trial of EVOLocumab Administered Very Early to Reduce the Risk of Cardiovascular Events in Patients Hospitalized With Acute Myocardial Infarction
    Medical condition: Dyslipidemia
    Disease: Version SOC Term Classification Code Term Level
    21.0 10027433 - Metabolism and nutrition disorders 10020604 Hypercholesterolemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-002235-26 Sponsor Protocol Number: OTR3002 Start Date*: 2011-10-26
    Sponsor Name:Purdue Pharma L.P.
    Full Title: An Open-label, Extension Study to Assess the Long-Term Safety of Twice Daily Oxycodone Hydrochloride Controlled-release Tablets in Opioid Experienced Children Who Completed the OTR3001 Study
    Medical condition: Opioid experienced paediatric patients aged 6-17 years with moderate to severe malignant and/or nonmalignant pain requiring opioid therapy.
    Disease: Version SOC Term Classification Code Term Level
    14.0 10042613 - Surgical and medical procedures 10002182 Analgesia LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: SE (Prematurely Ended) EE (Completed) ES (Completed) FI (Completed) DE (Completed) GR (Prematurely Ended) GB (Prematurely Ended) SK (Completed) BE (Completed) HU (Prematurely Ended) PL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-004939-39 Sponsor Protocol Number: GS-EU-174-1403 Start Date*: 2015-05-26
    Sponsor Name:Gilead Sciences International Ltd.
    Full Title: Pharmacoepidemiology study to define the long-term safety profile of tenofovir disoproxil fumarate (Tenofovir DF, Viread®) and describe the management of Tenofovir DF-associated renal and bone toxi...
    Medical condition: Chronic Hepatitis B
    Disease: Version SOC Term Classification Code Term Level
    18.0 10021881 - Infections and infestations 10008910 Chronic hepatitis B PT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed) GB (Prematurely Ended) ES (Prematurely Ended) BG (Prematurely Ended) GR (Completed) FR (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-003171-64 Sponsor Protocol Number: M16-534 Start Date*: 2018-10-30
    Sponsor Name:AbbVie Deutschland GmbH & Co.KG
    Full Title: Phase 3b Study for Management of Ocular Side Effects in Subjects with EGFR-Amplified Glioblastoma Receiving Depatuxizumab Mafodotin (ABT-414)
    Medical condition: EGFR-Amplified Newly diagnosed glioblastoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10018336 Glioblastoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) NL (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-003296-30 Sponsor Protocol Number: 00172 Start Date*: 2015-11-11
    Sponsor Name:Raimo Tuuminen
    Full Title: Efficacy of steroid and nonsteroidal anti-inflammatory eye drops in management of post-operative inflammation and prevention of pseudophakic cystic macular edema after uncomplicated cataract surgery
    Medical condition: Cataract senilis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-003217-20 Sponsor Protocol Number: 15073 Start Date*: 2016-03-23
    Sponsor Name:University of Nottingham
    Full Title: Management of recurrent pterygium to prevent visual impairment(REPEAT)
    Medical condition: RECURRENT PTERYGIUM
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-004653-96 Sponsor Protocol Number: PSD502-PM-002 Start Date*: 2006-01-30
    Sponsor Name:Plethora Solutions Limited
    Full Title: Phase II, single centre, randomised, double-blind, placebo-controlled study to determine the efficacy, safety and tolerability of PSD502 in the management of pain in subjects undergoing treatment f...
    Medical condition: Acute minor burns
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2006-003003-39 Sponsor Protocol Number: 06/075 Start Date*: 2006-08-10
    Sponsor Name:Academic Medical Center
    Full Title: Methotrexate versus expectant management in women with ectopic pregnancy (METEX study)
    Medical condition: Women with an ectopic pregnancy with low but plateauing serum hCG concentrations.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-003180-11 Sponsor Protocol Number: 15070 Start Date*: 2016-03-14
    Sponsor Name:University of Nottingham
    Full Title: Management of active and established corneal neovascularisation to prevent visual impairment
    Medical condition: Corneal new vessels
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-022114-12 Sponsor Protocol Number: MW012 Start Date*: 2010-12-20
    Sponsor Name:Dr. Willmar Schwabe GmbH & Co. KG
    Full Title: Multizentrische prospektive randomisierte kontrollierte offene Phase IV Studie zur Evaluation von Synergien zwischen WS® 1070 und strukturiertem Stressmanagement bei Patienten mit nachlassender Lei...
    Medical condition: Asthenia and decreased concentration capacity as well as fatigue and feeling of weakness along with subjective stress
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-016082-29 Sponsor Protocol Number: era-gastro-pancreas-001 Start Date*: 2010-03-10
    Sponsor Name:Erasme hospital
    Full Title: Role of Lanreotide in the Management of Paraduodenal Pancreatitis
    Medical condition: Paraduodenal pancreatitis
    Disease: Version SOC Term Classification Code Term Level
    12.1 10009093 Chronic pancreatitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-002130-23 Sponsor Protocol Number: TQLnephrectomi_v_1 Start Date*: 2017-07-28
    Sponsor Name:Zealand university hospital Roskilde
    Full Title: Ultrasoundguided Transmuscular Quadratus Lumborum(TQL) block for hand assisted laparoscopic nephrectomy - a randomized controlled trial
    Medical condition: The postoperative pain after Hand assisted lap.nephrectomy operation.Our one year retrospective study of patients with Kidney cancer treated with Hand assisted lap.nephrectomy revealed that, 71% of...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2010-021955-14 Sponsor Protocol Number: BUP3030 Start Date*: 2011-10-17
    Sponsor Name:Purdue Pharma L.P.
    Full Title: A Multicenter, Inpatient, Open-label Study to Characterize the Pharmacokinetics, Safety, and Efficacy of Intravenous Dosing of Buprenorphine in Pediatric Patients Aged from Birth to 6 Years of Age...
    Medical condition: Acute moderate to severe pain requiring opioids for at least 24 hours in postoperative and prolonged endotracheal intubated patients
    Disease: Version SOC Term Classification Code Term Level
    14.0 10042613 - Surgical and medical procedures 10002182 Analgesia LLT
    14.0 10042613 - Surgical and medical procedures 10021415 Immediate postoperative analgesia LLT
    Population Age: Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: HU (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-024402-35 Sponsor Protocol Number: 1403/WSHT/2010 Start Date*: 2012-05-11
    Sponsor Name:Sussex NHS Research Consortium
    Full Title: Clinical effectiveness of Transversus Abdominis Plane (TAP) block as postoperative analgesic in patients undergoing laparoscopic colorectal surgery: a double blinded randomised controlled trial
    Medical condition: Pain relief following laparoscopic colorectal resectional surgery (Benign and malignant)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10002182 Analgesia LLT
    14.1 10042613 - Surgical and medical procedures 10036276 Postoperative analgesia PT
    14.1 10042613 - Surgical and medical procedures 10021415 Immediate postoperative analgesia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-003167-38 Sponsor Protocol Number: NL50643.09r.r4 Start Date*: 2015-04-28
    Sponsor Name:Radboudumc
    Full Title: 68Ga-NODAGA-exendin-4 PET/CT in patients with AHH - a prospective comparative evaluation of preoperative imaging Under the FP7 project Betacure (602812); Personalized diagnosis and treatment of hy...
    Medical condition: Adult endogenous hyperinsulinemic hypoglycemia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed) FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-002169-23 Sponsor Protocol Number: DRYCHILD Start Date*: 2017-09-06
    Sponsor Name:Søren Rittig
    Full Title: The effect of clinical characterization of children with monosymptomatic nocturnal enuresis on the efficacy of desmopressin and alarm therapy.
    Medical condition: Enuresis nocturna
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004873 10014930 Enuresis (non-organic) LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DK (Completed) BE (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2021-002173-26 Sponsor Protocol Number: VX21-CTX001-151 Start Date*: 2021-10-05
    Sponsor Name:VERTEX PHARMACEUTICALS INCORPORATED
    Full Title: A Phase 3 Study to Evaluate the Safety and Efficacy of a Single Dose of CTX001 in Pediatric Subjects With Severe Sickle Cell Disease
    Medical condition: Severe Sickle Cell Disease (SCD)
    Disease: Version SOC Term Classification Code Term Level
    21.0 10010331 - Congenital, familial and genetic disorders 10040641 Sickle cell anaemia PT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: IT (Trial now transitioned) DE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2014-000562-21 Sponsor Protocol Number: PI-001 Start Date*: 2015-01-07
    Sponsor Name:VU University Medical Center
    Full Title: Amyloid-PET as a diagnostic marker in daily practice.
    Medical condition: Unselected patient population subjects visiting the memory clinic of the VUmc Alzheimer center.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-005010-59 Sponsor Protocol Number: THERAG0001 Start Date*: 2018-05-17
    Sponsor Name:Theragnostics Ltd
    Full Title: A Phase II, Open-label Study to Assess Safety and Clinical Utility of 68Ga-THP-PSMA PET/CT in Patients with High Risk Primary Prostate Cancer or Biochemical Recurrence after Radical treatment
    Medical condition: High Risk Primary Prostate Cancer or Biochemical Recurrence after Radical treatment
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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