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Clinical trials for Heart Failure

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44346   clinical trials with a EudraCT protocol, of which   7374   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    1,476 result(s) found for: Heart Failure. Displaying page 2 of 74.
    « Previous 1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2011-002236-92 Sponsor Protocol Number: 9151 Start Date*: 2011-08-11
    Sponsor Name:Maatschap cardiologie Isala klinieken Zwolle
    Full Title: Dopamine on top of standard treatment for patients with exacerbation of Heart Failure, at home situation
    Medical condition: exacerbation of Heart Failure treated at home
    Disease: Version SOC Term Classification Code Term Level
    13.1 10007541 - Cardiac disorders 10000803 Acute heart failure LLT
    13.1 10007541 - Cardiac disorders 10019284 Heart failure, congestive LLT
    13.1 10007541 - Cardiac disorders 10024106 Left heart failure LLT
    13.1 10007541 - Cardiac disorders 10064082 Heart failure NYHA class IV LLT
    13.1 10007541 - Cardiac disorders 10008908 Chronic heart failure LLT
    13.1 10007541 - Cardiac disorders 10064653 Acute decompensated heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-002367-34 Sponsor Protocol Number: 29052016 Start Date*: 2016-09-30
    Sponsor Name:Hjertemedicinsk klinik, Rigshospitalet
    Full Title: Beta 3 agonist treatment in heart failure (BEAT-HF II)
    Medical condition: Heart Failure
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004849 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2007-002809-48 Sponsor Protocol Number: CRO782 Start Date*: 2013-04-17
    Sponsor Name:Imperial College London and Imperial College Healthcare NHS Trust
    Full Title: Investigation of the safety and feasibility of AAV1/SERCA2a gene transfer in patients with chronic heart failure and a left ventricular assist device
    Medical condition: Advanced heart failure
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004849 10010684 Congestive heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-015005-39 Sponsor Protocol Number: MW005 Start Date*: 2009-11-03
    Sponsor Name:Dr. Willmar Schwabe GmbH & Co. KG
    Full Title: Monocentric prospective randomized controlled open phase IV study to explorate the mechanismen of the synergetic effect of the Crateagus -Extract WS® 1442 in addition to endurance training related ...
    Medical condition: heart failure, stage NYHA II
    Disease: Version SOC Term Classification Code Term Level
    12.0 10019279 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-004832-48 Sponsor Protocol Number: GN19CA407 Start Date*: 2020-12-17
    Sponsor Name:NHS Greater Glasgow and Clyde [...]
    1. NHS Greater Glasgow and Clyde
    2. University of Glasgow
    Full Title: DAPA-RESIST - Sodium glucose cotransporter-2 inhibitor DAPAgliflozin versus thiazide diuretic in patients with heart failure and diuretic RESISTance: a multi-centre, open-label, randomised controll...
    Medical condition: Diuretic resistant heart failure
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10010684 Congestive heart failure LLT
    20.0 100000004849 10066159 Decompensated heart failure LLT
    20.0 100000004849 10019279 Heart failure LLT
    20.0 10042613 - Surgical and medical procedures 10053073 Diuretic therapy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2016-003968-39 Sponsor Protocol Number: 2015CA02 Start Date*: 2017-09-19
    Sponsor Name:University of Dundee/NHS Tayside
    Full Title: Renal and Cardiovascular Effects of SGLT2 inhibition in combination with loop diuretics in diabetic patients with chronic heart failure.
    Medical condition: Type 2 diabetes and heart failure
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10008908 Chronic heart failure LLT
    20.0 100000004849 10010684 Congestive heart failure LLT
    20.0 100000004849 10019279 Heart failure LLT
    20.0 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-004186-40 Sponsor Protocol Number: CV019-010 Start Date*: 2020-06-18
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: A Randomized, Double-Blinded, Placebo-Controlled, Study to Evaluate the Safety and Tolerability of BMS-986259 in Stabilized Patients Hospitalized for Acute Decompensated Heart Failure
    Medical condition: Heart failure
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10019280 Heart failures HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) NL (Completed) GR (Completed) PL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-005607-92 Sponsor Protocol Number: QUIDHF_v3.0_20161130 Start Date*: 2016-08-04
    Sponsor Name:QUANTUM GENOMICS
    Full Title: A Phase II randomized, placebo controlled, double-blind, multi-centre study to assess safety and efficacy of incremental doses of QGC001 in patients upon discharge or following hospitalization for ...
    Medical condition: Patient with worsening chronic heart failure with left ventricular systolic dysfunction
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004849 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended) NO (Completed) GB (Prematurely Ended) PL (Prematurely Ended) HU (Prematurely Ended) CZ (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-001124-66 Sponsor Protocol Number: 15774603 Start Date*: 2016-07-08
    Sponsor Name:University Hospital Toulouse
    Full Title: Evaluation of the effect of double inhibition of angiotensin II AT1 receptor and neprilysin activity on sympatic nervous system activity in patient with heart failure (B2AN-SNS)
    Medical condition: Heart failure
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004849 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2017-001623-44 Sponsor Protocol Number: IRON-CRT-001 Start Date*: 2017-06-15
    Sponsor Name:Ziekenhuis Oost Limburg (ZOL), Genk
    Full Title: Effect of Intravenous Ferric Carboxymaltose on reverse remodeling following Cardiac Resynchronization therapy
    Medical condition: Heart failure with reduced left ventricular ejection fraction
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-002929-19 Sponsor Protocol Number: SCIENCE Start Date*: 2017-01-17
    Sponsor Name:Department of Cardiology, Rigshospitalet
    Full Title: Stem Cell therapy in IschEmic Non-treatable Cardiac disease - SCIENCE
    Medical condition: Ischemic heart disease and heart failure
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004849 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing) DK (Completed) SI (Completed) DE (Completed) AT (Ongoing) PL (Completed)
    Trial results: View results
    EudraCT Number: 2008-001779-31 Sponsor Protocol Number: FONDAPARINUX Start Date*: 2008-05-09
    Sponsor Name:AZIENDA OSPEDALIERA UNIVERSITARIA CAREGGI
    Full Title: Markers of hypercoagulability and risk of death and rehospitalization in heart failure patients: a pilot study on the effects of Fondaparinux
    Medical condition: heart failure patients (III-IV NYHA)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019280 Heart failures HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-003219-77 Sponsor Protocol Number: 2012-003219-77 Start Date*: 2012-12-20
    Sponsor Name:Copenhagen University Hospital, Rigshospitalet
    Full Title: Effects on Exercise Hemodynamics of Vasopressin Blockade by Conivaptan Infusion in Heart Failure
    Medical condition: Heart Failure
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004849 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2016-001513-25 Sponsor Protocol Number: 50268-20150921 Start Date*: 2016-05-12
    Sponsor Name:Aarhus University Hospital
    Full Title: Metformin in patients with chronic and acute heart failure: Pharmacokinetics and polymorphisms in genes encoding membrane metformin transporter proteins
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004849 10000803 Acute heart failure LLT
    19.0 100000004849 10008908 Chronic heart failure LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-001994-27 Sponsor Protocol Number: 2006B180 Start Date*: 2007-09-03
    Sponsor Name:Academisch Medisch Centrum
    Full Title: The effect of beta-adrenergic receptor blockade on sympathetic activity and coagulation in patients with heart failure (BACH-F study)
    Medical condition: Congestive heart failure
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010684 Congestive heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2023-001004-33 Sponsor Protocol Number: CLCZ696B2319E2 Start Date*: 2025-01-20
    Sponsor Name:Novartis Pharmaceuticals
    Full Title: A Safety Study of Sacubitril/​Valsartan in Japanese Pediatric Patients With Heart Failure Due to Systemic Left Ventricle Systolic Dysfunction Who Have Completed CLCZ696B2319E1 Study
    Medical condition: Heart Failure
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10019280 Heart failures HLGT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2017-001679-22 Sponsor Protocol Number: EMPA-UMCG-1 Start Date*: 2017-10-27
    Sponsor Name:Univeristy Medical Center Groningen
    Full Title: Randomized, double blind, placebo controlled, multicenter pilot study on the effects of empagliflozin on clinical outcomes in patients with acute decompensated heart failure
    Medical condition: Acute (decompensated) heart failure
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10019280 Heart failures HLGT
    20.0 100000004908 10019283 Heart failure signs and symptoms HLT
    20.0 100000011689 10000803 Acute heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-000126-19 Sponsor Protocol Number: SPIHF-204 Start Date*: 2016-08-01
    Sponsor Name:Stealth BioTherapeutics Inc.
    Full Title: A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Cardiac and Renal Effects of Short Term Treatment with Elamipretide in Patients Hospitalized with Congestion due to Hear...
    Medical condition: Congestive heart failure
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004849 10010684 Congestive heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LV (Completed) NL (Completed) ES (Completed) HU (Completed) GB (Completed) BG (Completed) BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001345-14 Sponsor Protocol Number: ZOLCAR17001 Start Date*: 2018-08-03
    Sponsor Name:Ziekenhuis Oost-Limburg Autonome Verzorgingsinstelling
    Full Title: A multi-center, randomized, double-blind, phase IV clinical trial on the diuretic effects of Acetazolamide (Diamox ®) in patients with Decompensated heart failure and Volume OveRload.
    Medical condition: The study population will consist of patients hospitalized with decompensated heart failure and demonstrating at least one clinical sign of volume overload.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10019284 Heart failure, congestive LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-002864-30 Sponsor Protocol Number: NL73019.018.20 Start Date*: 2020-07-29
    Sponsor Name:Amsterdam UMC, location AMC
    Full Title: Sulodexide for chronic heart failure: a proof of concept, randomized, placebo-controlled study
    Medical condition: Chronic heart failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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