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Clinical trials for Saline injection

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44349   clinical trials with a EudraCT protocol, of which   7376   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    133 result(s) found for: Saline injection. Displaying page 2 of 7.
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    EudraCT Number: 2006-003509-18 Sponsor Protocol Number: NAC0606 Start Date*: 2007-08-13
    Sponsor Name:University of Edinburgh [...]
    1. University of Edinburgh
    2. NHS Lothian Health Board
    Full Title: Mechanisms for the effect of acetylcysteine on renal function after exposure to radiographic contrast material
    Medical condition: Radiocontrast-induced nephropathy
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-000809-71 Sponsor Protocol Number: APPI2-PT-2019-01 Start Date*: 2019-06-18
    Sponsor Name:The Parker Institute, Bispebjerg and Frederiksberg Hospital, The Capital Region of Denmark
    Full Title: Direct comparison of intra-articular saline injections with an education plus exercise program for treatment of knee osteoarthritis symptoms: A randomised, open label, controlled, evidence based trial
    Medical condition: Knee osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10031165 Osteoarthritis knee LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2018-004159-19 Sponsor Protocol Number: 2018-00938 Start Date*: Information not available in EudraCT
    Sponsor Name:University Hospital Basel
    Full Title: Use of Copeptin Measurement after Arginine Infusion for the Diagnosis of Diabetes Insipidus - the CARGOx Study
    Medical condition: Polyuria-polydipsia syndrome (PPS) is divided into the three main entities central (complete or partial) diabetes insipidus (DI), nephrogenic DI and primary polydipsia (PP).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing) NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-004863-69 Sponsor Protocol Number: 108494, 108516, 108518, 108520 Start Date*: 2006-12-22
    Sponsor Name:GlaxoSmithKline Biologicals
    Full Title: A phase II, single-blind, randomized, controlled, multicentre vaccination study to evaluate the safety and immune response of the GSK Biologicals Zoster vaccine, gE/AS01B, and to compare 3 doses of...
    Medical condition: Primary immunization of healthy elderly subjects (60 to 69 and more than or equal to 70 years) against zoster
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) SE (Completed) CZ (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2020-004034-38 Sponsor Protocol Number: MK-7684A-002 Start Date*: 2021-04-19
    Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc
    Full Title: A Phase 2, Multicenter, Randomized Study to Compare the Efficacy and Safety of MK-7684A or MK-7684A Plus Docetaxel Versus Docetaxel Monotherapy in the Treatment of Participants With Metastatic Non-...
    Medical condition: Non Small Cell Lung cancer
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10059515 Non-small cell lung cancer metastatic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Trial now transitioned) DK (Trial now transitioned) DE (Trial now transitioned) BE (Trial now transitioned) AT (Trial now transitioned) PL (Trial now transitioned) FR (Trial now transitioned) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-000821-62 Sponsor Protocol Number: ATR-2011 Start Date*: 2011-09-19
    Sponsor Name:Consorci Sanitari Terrassa
    Full Title: Comparación de la efectividad analgésica del bloqueo femoral, la infiltración intraarticular o la combinación de ambas en el control del dolor en la artroplastia total de rodilla.
    Medical condition: artroplastia total de rodilla
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-005757-12 Sponsor Protocol Number: FAIR-HFpEF Start Date*: 2017-06-06
    Sponsor Name:Charité – Universitätsmedizin Berlin
    Full Title: Effect of IV iron (ferric carboxymaltose, Ferinject) on exercise tolerance, symptoms and quality of life in patients with heart failure with preserved ejection fraction (HFpEF) and iron deficiency ...
    Medical condition: Patients with heart failure with preserved ejection fraction (HFpEF) and iron deficiency (ID) with and without anaemia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-003939-38 Sponsor Protocol Number: P160404J Start Date*: 2017-12-19
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Short-term efficacy of a single ultrasound-guided intra-articular injection of botulinum toxin A associated with splinting for base-of-thumb osteoarthritis on pain at 3 months: A randomized placebo...
    Medical condition: Patients referred to our Physical Medicine Rehabilitation Department of a tertiary care center in Paris, France, for the management of Base-of-thumb osteoarthritis (BTOA)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10062893 Rhizarthrosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2017-004188-11 Sponsor Protocol Number: MK-3475-789 Start Date*: 2018-05-09
    Sponsor Name:Merck Sharp & Dohme LLC
    Full Title: A Randomized, Double-Blind, Phase 3 Study of Pemetrexed + Platinum Chemotherapy with or without Pembrolizumab (MK-3475) in TKI-resistant EGFR-mutated Tumors in Metastatic Non-squamous Non-small Cel...
    Medical condition: Metastatic Non-squamous Non-small Cell Lung Cancer
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029522 Non-small cell lung cancer stage IV PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) ES (Completed) FR (Completed) DE (Completed) GB (GB - no longer in EU/EEA) IT (Completed)
    Trial results: View results
    EudraCT Number: 2020-005547-23 Sponsor Protocol Number: 12217 Start Date*: 2021-07-22
    Sponsor Name:AZ Delta vzw
    Full Title: Management of Popeye sign with botulinum toxin after tenotomy of the long head of the biceps tendon: a double-blinded randomized controlled trial
    Medical condition: Popeye sign or cramping pain after shoulder artroscopy with biceps tenotomy
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004343-12 Sponsor Protocol Number: ICARISTrialProtocol Start Date*: 2015-10-07
    Sponsor Name:Mater Research Institute University of Queensland
    Full Title: Impact on Caesarean Section Rates Following Injections of Sterile Water
    Medical condition: Back pain in labour and childbirth
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-003252-38 Sponsor Protocol Number: Hx-Inflam-302 Start Date*: 2006-09-01
    Sponsor Name:Genmab A/S
    Full Title: An open label clinical pilot study with local injection of human antibody (HuMax-Inflam) for the treatment of inflammatory psoriasis
    Medical condition: inflammatory psoriasis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10037153 Psoriasis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2006-004565-33 Sponsor Protocol Number: EASI Start Date*: 2006-11-16
    Sponsor Name:Chemische Fabrik Kreussler & Co.GmbH
    Full Title: Efficacy and safety of Aethoxysklerol compared to Sodium Tetradecyl Sulfate and Isotonic Saline (placebo) for the treatment of reticular veins and spider veins including subgroup to investigate the...
    Medical condition: Patients suffering from varicose veins (spider veins or reticular veins in the legs) should be treated with a sclerosing agent.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10047001 Varicose veins LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2014-002319-41 Sponsor Protocol Number: HULP-VIR-2014-01 Start Date*: 2015-05-11
    Sponsor Name:Ana Boto de los Bueis
    Full Title: Clinical and virologic assesment of two therapeutic options: antiviral Ganciclovir 0.15% ophthalmic gel and physiologic saline solution 0.9% used in patients with acute adenoviral conjuntivitis.
    Medical condition: Acute adenoviral conjunctivitis
    Disease: Version SOC Term Classification Code Term Level
    18.0 10021881 - Infections and infestations 10001257 Adenoviral conjunctivitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-004485-28 Sponsor Protocol Number: 38RC15.214 Start Date*: 2016-01-18
    Sponsor Name:Centre Hospitalier Universitaire de Grenoble
    Full Title:
    Medical condition: Patients should be operated for cardiac surgery with cardiac bypass and in sinus rhythm, and for which the fact of the existence of impaired left ventricular function or the heaviness of the surgic...
    Disease: Version SOC Term Classification Code Term Level
    18.1 10042613 - Surgical and medical procedures 10061026 Cardiac operation PT
    Population Age: Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2022-002717-41 Sponsor Protocol Number: TRAPEZIUS Start Date*: 2023-06-27
    Sponsor Name:HOSPITAL CLINIC DE BARCELONA
    Full Title: EFFICACY AND SAFETY OF LOCAL TREATMENT OF TRAPEZIUS MYOFASCIAL SYNDROME IN PATIENTS WITH FIBROMYALGIA THROUGH ULTRASOUND-GUIDED INTERFASCIAL BLOCK OF THE TRAPEZIUS MUSCLE
    Medical condition: TRAPEZIUS MYOFASCIAL SYNDROME IN FIBROMYALGIA PATIENTS
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-006583-35 Sponsor Protocol Number: 06/Q2601/33 Start Date*: 2007-02-13
    Sponsor Name:Shrewsbury & Telford Hospital NHS Trust
    Full Title: A comparison of two diluents commonly used in epidural steroid injection for the treatment of low back pain and sciatica
    Medical condition: Low back pain and sciatica
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003989 Back pain (with radiation) LLT
    Population Age: Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-013620-22 Sponsor Protocol Number: SOFISEP Start Date*: 2009-10-07
    Sponsor Name:AZIENDA SANITARIA LOCALE BI DI BIELLA
    Full Title: Multicenter randomized open clinical trial for `lock` efficacy assessment of totally implantable vascular access device with saline solution vs heparin
    Medical condition: Cancer patients with totally implantable vascular access device
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-001221-10 Sponsor Protocol Number: 2602-637 Start Date*: 2008-11-10
    Sponsor Name:Rigshospitalet, University of Copenhagen
    Full Title: Postconditioning used for the limitation of infarct size in patients with ST-elevation myocardial infarction (POSTCON).
    Medical condition: Patients with ST-segment elevation myocardial infarction (STEMI) are routinely treated with primary PCI (pPCI) as a world wide standard. Glucagon like peptide (GLP1) is a genuine hormone created in...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-002124-32 Sponsor Protocol Number: CUSA-081-HEM-01 Start Date*: 2020-01-02
    Sponsor Name:Chiesi Farmaceutici S.p.A.
    Full Title: READY 1: A Phase 3, Randomized, Double-Blind, Active and Placebo-Controlled Study on the use of CUSA-081 for Dysfunctional Central Venous Access Devices (CVADs)
    Medical condition: Catheter Occlusion Thrombosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) BE (Completed) ES (Prematurely Ended) RO (Ongoing)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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