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Clinical trials for Simvastatin (Zocor)

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    41 result(s) found for: Simvastatin (Zocor). Displaying page 2 of 3.
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    EudraCT Number: 2005-005981-35 Sponsor Protocol Number: NK-104-309 Start Date*: 2006-06-22
    Sponsor Name:Kowa Research Europe Ltd.
    Full Title: DOUBLE-BLIND FOLLOW-ON STUDY OF PITAVASTATIN (4 MG) VERSUS SIMVASTATIN (40 MG AND 80 MG), WITH A SINGLE-BLIND EXTENSION OF TREATMENT, IN PATIENTS WITH PRIMARY HYPERCHOLESTEROLEMIA OR COMBINED DYSLI...
    Medical condition: Primary Hypercholesterolemia or Combined Dyslipidemia and 2 or More Risk Factors for Coronary Heart Disease
    Disease: Version SOC Term Classification Code Term Level
    8.1 10020604 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) SE (Completed) ES (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2006-005906-30 Sponsor Protocol Number: 442006 Start Date*: 2007-08-06
    Sponsor Name:Universitätsklinikum Freiburg, Abteilung klinische Chemie
    Full Title: The effect of Ezetimibe 10 mg, Simvastatin 20 mg and the Combination of Simvastatin 20 mg plus 10 mg Ezetimibe on LDL-Subfractions in patients with Type 2 Diabetes (Die Wirkung einer Monotherapie m...
    Medical condition: well controlled type II diabetes mellitus (HbA1c < 8.0 %) with a preponderance of atherogenic small, dense LDL (LDL-5 and LDL-6 > 25 mg/dL)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-006557-28 Sponsor Protocol Number: FENOPRA-III-06-1 Start Date*: 2007-05-07
    Sponsor Name:Laboratoires SMB S.A.
    Full Title: A phase III, four-armed, randomised, double blind, parallel study to compare the efficacy and safety in type 2 diabetic patients with combined hyperlipidemia of a 12-week administration of Fenofibr...
    Medical condition: Type 2 diabetic patients, as defined by the WHO without CVD and with CVD (Cardiovascular disease), with combined hyperlipidemia.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10027763 Mixed hyperlipidemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) HU (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-001007-12 Sponsor Protocol Number: MK-0524B-143 Start Date*: 2011-07-29
    Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
    Full Title: A Phase III Multicenter, Double-Blind, Crossover Design Study to Evaluate Lipid-Altering Efficacy and Safety of 1 g/10 mg Extended-Release Niacin/Laropiprant/Simvastatin Combination Tablets in Pati...
    Medical condition: Primary Hypercholesterolemia & Mixed Dyslipdemia
    Disease: Version SOC Term Classification Code Term Level
    13.1 10027433 - Metabolism and nutrition disorders 10058110 Dyslipidemia LLT
    13.1 10027433 - Metabolism and nutrition disorders 10020604 Hypercholesterolemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) DE (Prematurely Ended) LT (Prematurely Ended) NL (Prematurely Ended) LV (Prematurely Ended) CZ (Prematurely Ended) NO (Prematurely Ended) SK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-001885-17 Sponsor Protocol Number: CTSUTHRIVE1 Start Date*: 2006-09-26
    Sponsor Name:University of Oxford
    Full Title: HPS2-THRIVE (Treatment of HDL to Reduce the Incidence of Vascular Events): A randomized trial of the long-term clinical effects of raising HDL cholesterol with niacin and MK-0524.
    Medical condition: Cardiovascular disease: History of myocardial infarction; or cerebrovascular atherosclerotic disease (history of presumed ischaemic stroke, transient ischaemic attack or carotid revascularisation);...
    Disease: Version SOC Term Classification Code Term Level
    9.0 10051615 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) DK (Completed) SE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-000037-19 Sponsor Protocol Number: 0524B-024 Start Date*: 2008-07-15
    Sponsor Name:Merck & Co., Inc.
    Full Title: A Multicenter, Randomized, Double-Blind, Parallel Group, 12 Week Study to Evaluate the Efficacy and Safety of MK-0524B (dosed as coadministered MK-0524A and Simvastatin Tablets) Versus Atorvastatin...
    Medical condition: Mixed Hyperlipidemia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10027763 Mixed hyperlipidemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed) ES (Completed) SE (Completed) GB (Completed) FI (Completed)
    Trial results: View results
    EudraCT Number: 2005-001037-15 Sponsor Protocol Number: NK-104-304 Start Date*: 2006-05-17
    Sponsor Name:Kowa Research Europe Ltd.
    Full Title: STUDY OF PITAVASTATIN 4 MG vs. SIMVASTATIN 40 MG (FOLLOWING UP- TITRATION) IN PATIENTS WITH PRIMARY HYPERCHOLESTEROLEMIA OR COMBINED DYSLIPIDEMIA AND 2 OR MORE RISK FACTORS FOR CORONARY HEART DISEASE
    Medical condition: Hypercholesterolemia or Combined Dyslipidemia and 2 or more risk factors for coronary heart disease (CHD)
    Disease: Version SOC Term Classification Code Term Level
    7.1 10020604 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) GB (Completed) DK (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2012-001868-29 Sponsor Protocol Number: MK-0431D-266 Start Date*: 2013-02-04
    Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
    Full Title: A Phase III, Randomized, Double-Blind, Clinical Trial to Study the Efficacy and Safety of MK-0431D (a fixed-dose combination [FDC] of sitagliptin and simvastatin) for the Treatment of Patients With...
    Medical condition: Type 2 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    14.1 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Completed) LV (Completed) HU (Prematurely Ended) CZ (Prematurely Ended) PL (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-000519-21 Sponsor Protocol Number: C LF0242780-01 05 03 Start Date*: 2006-06-29
    Sponsor Name:FOURNIER LABORATORIES IRELAND Ltd
    Full Title: A multicenter, double-blind, randomized, forced-titration study to compare the efficacy and safety of the combination of 145 mg fenofibrate and 20 or 40 mg simvastatin with atorvastatin monotherapy...
    Medical condition: Study in patients with mixed dyslipidemia at risk of cardiovascular disease not adequately controlled by 10 mg atorvastatin alone
    Disease: Version SOC Term Classification Code Term Level
    8.1 10027763 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Completed) CZ (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-003093-21 Sponsor Protocol Number: 20091977 Start Date*: Information not available in EudraCT
    Sponsor Name:Medical Department I
    Full Title: Influence of combined therapy of niacin and statins on stem cell mobilization and inflammatory parameters in patients suffering from coronary artery disease – randomized clinical study -
    Medical condition: Have stable coronary artery disease (i.e. no acute event like myocardial infarction or PTCA less then 3 months ago)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-002017-39 Sponsor Protocol Number: 0524-067 Start Date*: 2007-07-11
    Sponsor Name:Merck & Co., Inc.
    Full Title: A Multicenter, Randomized, Double-Blind, Parallel Group, 12-Week Study to Evaluate the Efficacy and Safety of Extended-Release (ER) Niacin/Laropiprant Added to Statin Versus Doubling the Dose of St...
    Medical condition: Hypercholesterolemia or Mixed Dyslipidemia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020604 Hypercholesterolemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) DE (Completed) FR (Completed) CZ (Completed) SE (Completed) NL (Completed) AT (Completed) HU (Completed) IT (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2010-023939-42 Sponsor Protocol Number: MK-0524B-118 Start Date*: 2011-05-18
    Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
    Full Title: A Phase III Multicenter, Double-Blind, Crossover Design Study to Evaluate Lipid-Altering Efficacy and Safety of Extended-Release Niacin/Laropiprant/Simvastatin Combination Tablet in Patients with P...
    Medical condition: Primary Hypercholesterolemia & Mixed Dyslipdemia
    Disease: Version SOC Term Classification Code Term Level
    13.1 10027433 - Metabolism and nutrition disorders 10058110 Dyslipidemia LLT
    13.1 10027433 - Metabolism and nutrition disorders 10020604 Hypercholesterolemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) DE (Prematurely Ended) BG (Prematurely Ended) ES (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-001579-32 Sponsor Protocol Number: RHF0001 Start Date*: 2008-09-22
    Sponsor Name:University of Hertfordshire
    Full Title: Erectile dysfunction:a randomised controlled trial of lipid lowering with simvastatin (EDS trial)
    Medical condition: Erectile dysfunction
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061461 Erectile dysfunction LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-002414-40 Sponsor Protocol Number: CXA-10-2302 Start Date*: 2019-12-17
    Sponsor Name:Complexa Inc.
    Full Title: A Phase 2, Multi-Center, Open-Label Study to Evaluate Long-term Safety and Efficacy of CXA-10 in Subjects with Pulmonary Arterial Hypertension on Stable Background Therapy: Extension to Study CXA-1...
    Medical condition: Pulmonary Arterial Hypertension (PAH).
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10064911 Pulmonary arterial hypertension PT
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10064911 Pulmonary arterial hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-019720-32 Sponsor Protocol Number: P-100820-01 Start Date*: 2010-07-08
    Sponsor Name:Ferrer Internacional, S.A.
    Full Title: Cardiovascular Fixed Combination Pill ASR: ensayo clínico farmacodinámico de la combinación a dosis fijas de ácido acetilsalicílico, simvastatina, y ramipril (Cardiovascular Polypill); Colesterol L...
    Medical condition: terapia sustitutiva para la prevención de accidentes cardiovasculares Substitution therapy to prevent cardiovascular accidents
    Disease: Version SOC Term Classification Code Term Level
    11 10064939 Profilaxis cardiovascular PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-022516-39 Sponsor Protocol Number: SIMBETA Start Date*: 2011-10-27
    Sponsor Name:Institut de Recerca HSCSP
    Full Title: Estudio aleatorizado sobre el efecto hemodinámico de la asociación de simvastatina con betabloqueantes no cardioselectivos en pacientes con cirrosis hepática e hipertensión portal clínicamente ...
    Medical condition: Se trata de un estudio hemodinámico, para el estudio del efecto en la progresión de hipertensión portal, de la asociación de simvastatina al tratamiento convencional de la profilaxis primaria en pa...
    Disease: Version SOC Term Classification Code Term Level
    13 10019654 Trastornos hepáticos y hepatobiliares HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2009-017479-29 Sponsor Protocol Number: I1V-MC-EIAF Start Date*: 2010-07-30
    Sponsor Name:Eli Lilly and Company
    Full Title: A Phase 2 Efficacy and Safety Study of LY2484595 Alone and in Combination with Atorvastatin, Simvastatin, and Rosuvastatin in Patients with Hypercholesterolemia or Low HDL-C
    Medical condition: Hypercholesterolemia or Low HDL-C
    Disease: Version SOC Term Classification Code Term Level
    12.1 10020604 Hypercholesterolemia LLT
    12.1 10024915 Low HDL LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) DK (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-004876-19 Sponsor Protocol Number: 01-05-TL-475-021 Start Date*: 2006-02-13
    Sponsor Name:Takeda Europe R&D Centre Ltd
    Full Title: A Double-Blind, Randomized Study to Evaluate the Efficacy and Safety of TAK-475 100 mg or Placebo When Co-Administered With High Dose Statin Therapy in Subjects With Primary Hypercholesterolemia
    Medical condition: Treatment of patients with primary hypercholesterolemia currently taking atorvastatin (80mg), simvastatin (80mg) or rosuvastatin (40mg)
    Disease: Version SOC Term Classification Code Term Level
    8 10058108 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) ES (Completed) SE (Prematurely Ended) NO (Completed) FI (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-021593-11 Sponsor Protocol Number: SIMPRO2010 Start Date*: 2011-04-19
    Sponsor Name:INSTITUT DE RESERCA.HSCSP
    Full Title: Prevención de la progresión de la hipertensión portal en la cirrosis compensada mediante el uso de vasodilatadores hepáticos selectivos. Estudio multicéntrico, aleatorizado y doble-ciego
    Medical condition: El objetivo de estudio es valorar el efecto de las estatinas, en su efecto vasodilatador selectivo hepático, en la prevención de la progresión de la hipertensión portal ( con un gradiente de presió...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10036201 Portal hypertensions HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-019874-34 Sponsor Protocol Number: PPT01 Start Date*: 2010-11-05
    Sponsor Name:Queen Mary University of London
    Full Title: A randomised, placebo controlled, double-blind, cross-over trial of the Polypill on risk factor reduction
    Medical condition: Hypercholesterolaemia and Hypertension
    Disease: Version SOC Term Classification Code Term Level
    N/A 10020603 Hypercholesterolaemia LLT
    N/A 10020772 Hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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