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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    8,950 result(s) found. Displaying page 26 of 448.
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    EudraCT Number: 2011-006301-10 Sponsor Protocol Number: MAGNA Start Date*: 2012-05-10
    Sponsor Name:Fundació Clinic per a la Recerca Biomèdica
    Full Title: Perioperative Magnesium Sulphate as a cerebral protector in neurosurgical patients
    Medical condition: Patient who are going to be under cerebral parenchyma resection, due to epilepsy or tumor
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10039911 Seizures (incl subtypes) HLGT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006153 Brain tumor LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-006304-13 Sponsor Protocol Number: ASCOMCOGI Start Date*: 2012-06-26
    Sponsor Name:AZIENDA OSPEDALIERA CARDARELLI
    Full Title: Effetto del precursore colinergico colina alfoscerato sui sintomi cognitivi e comportamentali in pazienti affetti da danno cognitivo lieve (mild cognitive impairment)
    Medical condition: mild cognitive impairment
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10029205 Nervous system disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-005134-38 Sponsor Protocol Number: ABRAMYO Start Date*: 2014-03-19
    Sponsor Name:ISTITUTI FISIOTERAPICI OSPITALIERI - IRE
    Full Title: Phase I-II study of weekly nab (nanoparticle albumin-bound)-paclitaxel (nab-paclitaxel) in combination with liposomal encapsulated doxorubicin (LDox) in patients with HER2 negative metastatic breas...
    Medical condition: Her2 negative metastatic breast cancer first line
    Disease: Version SOC Term Classification Code Term Level
    16.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006198 Breast cancer recurrent PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-005325-23 Sponsor Protocol Number: SGB_HF_MEN Start Date*: 2014-06-20
    Sponsor Name:Rijnstate Hospital
    Full Title: Short-term Efficacy of Stellate Ganglion Block in Men to reduce Hot Flushes related to Androgen Deprivation Therapy
    Medical condition: Hot flushes due to androgen deprivation therapy
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-005363-52 Sponsor Protocol Number: IOCtrial Start Date*: 2014-09-10
    Sponsor Name:Department of Neurology, Academic Medical Center
    Full Title: Intravenous immunoglobulin overtreatment in chronic inflammatory demyelinating polyneuropathy (CIDP)
    Medical condition: Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-000619-10 Sponsor Protocol Number: RUNMC-EX-BCM-2012 Start Date*: 2012-07-24
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: Clinical proof-of-principle of the determination of the beta cell mass in vivo by SPECT imaging with the 111In-labeled GLP-1 analogue DTPA-[K40]-Exendin 4
    Medical condition: patients with long-standing type 1 diabetes
    Disease: Version SOC Term Classification Code Term Level
    14.1 10014698 - Endocrine disorders 10018424 Glucose metabolism disorders (incl diabetes mellitus) HLGT
    14.1 10014698 - Endocrine disorders 10012602 Diabetes mellitus (incl subtypes) HLT
    14.1 10027433 - Metabolism and nutrition disorders 10012601 Diabetes mellitus PT
    14.1 10027433 - Metabolism and nutrition disorders 10067584 Type 1 diabetes mellitus PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-024549-65 Sponsor Protocol Number: RBHP_2010_CONSTANTIN_3 Start Date*: 2012-04-06
    Sponsor Name:CHU Clermont-Ferrand
    Full Title: Impact du remplissage vasculaire sur l’œdème pulmonaire mesuré par la clairance alvéolaire chez des patients atteints de SDRA.
    Medical condition: patients de réanimation intubés/ventilés et atteint de SDRA
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-000047-33 Sponsor Protocol Number: VitD-EX1.0 Start Date*: 2014-03-20
    Sponsor Name:VU University Medical Centre
    Full Title: The effect of high-resistance muscle strength training and vitamin D supplementation in persons with knee osteoarthritis
    Medical condition: knee osteoarthritis vitamin D deficiency
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-006115-59 Sponsor Protocol Number: GNM-2011 Start Date*: 2012-06-11
    Sponsor Name:AZIENDA OSPEDALIERA SPEDALI CIVILI DI BRESCIA
    Full Title: "A Randomized Controlled Trial of Rituximab Versus Steroids and Cyclophosphamide in the Treatment of Idiopathic Membranous Nephropathy (IMN)"
    Medical condition: MN is an autoimmune disease, suggesting that the disease may be triggered by isotype specific autoantibodies directed against podocyte enzymes and podocyte receptors that are recognized as antigens...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038359 - Renal and urinary disorders 10018372 Glomerulonephritis membranous PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-000517-31 Sponsor Protocol Number: ANST_2014_KET Start Date*: 2014-06-10
    Sponsor Name:Leiden University Medical Center
    Full Title: Effect of perioperative ketamine on postoperative outcome – a randomized placebo-controlled trial
    Medical condition: Postoperative cognitive state
    Disease: Version SOC Term Classification Code Term Level
    17.0 10022117 - Injury, poisoning and procedural complications 10049987 Confusion postoperative PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-003098-88 Sponsor Protocol Number: PED/VITD/1 Start Date*: 2014-02-26
    Sponsor Name:Consorci Mar Parc de Salut de Barcelona (Parc de Salut Mar) [...]
    1. Consorci Mar Parc de Salut de Barcelona (Parc de Salut Mar)
    2. Kern Pharma, S.L.
    Full Title: An open, controlled, double-blind, with placebo clinical trial and randomized in subgroups of pediatric patients with allergic and non-allergic asthma, with deficiency, insufficiency or normal leve...
    Medical condition: One hundred and sixty children with allergic or non-allergic asthma, deficit, insufficiency or normal levels of Vitamin D.
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-003100-39 Sponsor Protocol Number: NSGA Start Date*: 2013-11-28
    Sponsor Name:Dutch Growth Research Foundation
    Full Title: Standardized versus individualized growth hormone treatment of short children born small for gestational age: Effects on short-term and longterm efficacy, long-term psychosocial development, gluc...
    Medical condition: Children who are born small for gestational age, defined as a birth length and/or birth weight < -2 SD score, who fail to show catch-up growth (short stature).
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004848 10018747 Growth hormone LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-002799-42 Sponsor Protocol Number: CAPstatin2013 Start Date*: 2014-03-27
    Sponsor Name:Dipartimento di Medicina Interna e Specialità Mediche - Policlinico Umberto I - Sapienza Università di Roma
    Full Title: Statins in the prevention of myocardial damage in pneumonia
    Medical condition: Patients hospitalized with community-acquired pneumonia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-004269-15 Sponsor Protocol Number: D-13-01 Start Date*: 2014-03-17
    Sponsor Name:Insituto Aragonés de Ciencias de la Salud
    Full Title: Aspirin and colorectal cancer prevention. Exploring the platelet hypothesis of its mechanism of action
    Medical condition: We will perform this clinical study to address the hypothesis that low-dose aspirin given once daily is acting primarily by selectively acetylating platelet COX-1 and suppressing its activity throu...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-001829-76 Sponsor Protocol Number: ProsMaMa13.1 Start Date*: 2013-10-04
    Sponsor Name:Paula Diéguez García
    Full Title: INTERCOSTAL BRANCHES BLOCK IN THE MIDAXILLARY LINE VERSUS PARAVERTEBRAL BLOCK, ULTRASOUND-GUIDED FOR NOT RECONSTRUCTIVE BREAST SURGERY. RANDOMIZED CLINICAL TRIAL
    Medical condition: Sheduled patients for nor reconstructive unilateral breast surgery
    Disease: Version SOC Term Classification Code Term Level
    16.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10057654 Breast cancer female PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-001834-16 Sponsor Protocol Number: AD101_01 Start Date*: 2014-01-10
    Sponsor Name:ISTITUTI FISIOTERAPICI OSPITALIERI
    Full Title: EVALUATION OF SEIZURE CONTROL AND QUALITY OF LIFE IN PATIENTS WITH BRAIN TUMOR RELATED EPILEPSY TREATED WITH LACOSAMIDE AS ADD-ON THERAPY: A PROSPECTIVE EXPLORATIVE STUDY
    Medical condition: PATIENTS WITH BRAIN TUMOR RELATED EPILEPSY
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004852 10068330 Symptomatic epilepsy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-002165-19 Sponsor Protocol Number: NL4487800013 Start Date*: 2013-07-25
    Sponsor Name:Medical Center Leeuwarden
    Full Title: Hypernatraemia and diuretics
    Medical condition: Intensive Care admission sodium level in plasma > 142 mmol/L
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-004834-14 Sponsor Protocol Number: POLAR_2013 Start Date*: 2014-03-31
    Sponsor Name:
    Full Title: Treatment of port wine stains using Pulsed Dye Laser, Erbium Yag Laser and topical sirolimus in an open label pilot study (POLAR).
    Medical condition: Port Wine Stain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-004863-30 Sponsor Protocol Number: MG Start Date*: 2014-01-14
    Sponsor Name:Università Campus Bio-Medico di Roma
    Full Title: EVALUATION OF EFFECT OF MAGNESIUM SULFATE ADDED TO THE ropivacaine for the sciatic nerve block at popliteus
    Medical condition: Hallux valgus correction
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004865 10011123 Correction Hallux Valgus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-001743-31 Sponsor Protocol Number: NL43882.029.13 Start Date*: 2013-08-06
    Sponsor Name:VU University Medical Center
    Full Title: The cardiovascular effects of hyperoxia during and shortly after CABG surgery
    Medical condition: During and after coronary artery bypass graft operation we will investigate the cardiovascular effects of hyperoxia on blood pressure, cardiac function, microcirculation and ischemia/reperfusion.
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004866 10051615 Atherosclerotic cardiovascular disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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