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Clinical trials for II

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44393   clinical trials with a EudraCT protocol, of which   7405   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    11,933 result(s) found for: II. Displaying page 276 of 597.
    EudraCT Number: 2008-001004-22 Sponsor Protocol Number: CRH 06/374/M Start Date*: 2008-07-09
    Sponsor Name:Centre René Huguenin
    Full Title: A multicentre phase II trial to determine the efficacy of the anti-tyrosine kinase sunitinib (SUTENT®) as second line therapy in patients with transitional cell carcinoma (TCC) of the urothelium wh...
    Medical condition: Histologically proven advanced TCC (transitional cell carcinoma) of the urothelium
    Disease: Version SOC Term Classification Code Term Level
    9.1 10044420 Transitional cell carcinoma of the bladder stage unspecified LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-006097-10 Sponsor Protocol Number: SPOT 1.9-2005 Start Date*: 2006-09-25
    Sponsor Name:Universitätsklinikum Essen
    Full Title: Pilot study of dose-escalated radiotherapy with PET/CT based treatment planning in combination with induction and concurrent chemotherapy in locally advanced (uT3/T4) squamous cell cancer of the es...
    Medical condition: Phase II study of dose-intensified radiation therapy based on PET/CT-Planning in combination with induction- and concurrent chemotherapy in locally advanced squamous cell carcinomas (uT3/T4) of the...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Restarted)
    Trial results: (No results available)
    EudraCT Number: 2014-003790-41 Sponsor Protocol Number: JAN12006-01 Start Date*: 2015-05-11
    Sponsor Name:Spherium Biomed
    Full Title: Randomised, double-blinded, placebo and active comparator controlled exploratory clinical trial to assess the efficacy and safety of a triple combination of Ibuprofen, magnesium and ascorbic acid ...
    Medical condition: Temporomandibular joint dysfunction syndrome.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-002321-20 Sponsor Protocol Number: HIDRA04 Start Date*: 2015-09-01
    Sponsor Name:Hellenic Institute for the Study of Sepsis
    Full Title: A DOUBLE-BLIND, RANDOMISED, PLACEBO-CONTROLLED CLINICAL TRIAL OF THE SAFETY AND EFFICACY OF MABp1, A HUMAN ANTIBODY TARGETING INTERLEUKIN-1ALPHA, IN PATIENTS WITH HIDRADENITIS SUPPURATIVA
    Medical condition: HIDRADENITIS SUPPURATIVA/ACNE INVERSA
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004858 10020041 Hidradenitis suppurativa LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-000269-27 Sponsor Protocol Number: DSCK101 Start Date*: 2014-11-06
    Sponsor Name:German Foundation for Chronically Ill
    Full Title: Efficacy and tolerance of Beta Blocker and Procoralan uptitration in chronic heart failure patients under telemedical control: „70 bpm on day 28“
    Medical condition: Patients with chronic heart failure and resting heart rate of ≥ 75 bmp
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-005052-25 Sponsor Protocol Number: AOP00101 Start Date*: 2015-06-29
    Sponsor Name:AZIENDA OSPEDALIERA DI PADOVA
    Full Title: Total versus corrected body weight for dosage of sugammadex in morbidly obese patients.
    Medical condition: Reversal of rocuronium-induced neuromuscular blockade
    Disease: Version SOC Term Classification Code Term Level
    18.0 10042613 - Surgical and medical procedures 10057286 Neuromuscular blockade reversal PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-002395-24 Sponsor Protocol Number: PM60184-B-001-15 Start Date*: 2015-12-09
    Sponsor Name:Pharma Mar, S.A. , Sociedad Unipersonal
    Full Title: Phase II, Open-Label, Randomized, Controlled Study of PM060184 in Advanced, Hormone Receptor Positive, HER2 negative Breast Cancer Patients in Third or Fourth Line Setting.
    Medical condition: Breast Cancer
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004864 10072737 Advanced breast cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2018-004015-49 Sponsor Protocol Number: FLU010 Start Date*: 2019-03-14
    Sponsor Name:Vaccitech Ltd
    Full Title: Efficacy of MVA-NP+M1 in the influenza H3N2 Human Challenge model
    Medical condition: influenza disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10022005 Influenza viral infections HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2014-004386-24 Sponsor Protocol Number: PEGACRO Start Date*: 2015-12-04
    Sponsor Name:DIPARTIMENTO DI MEDICINA CLINICA E CHIRURGIA - UNIVERSITÀ DEGLI STUDI DI NAPOLI FEDERICO II
    Full Title: Effect of GH receptor antagonist on insulin resistance associated with acromegaly
    Medical condition: acromegaly
    Disease: Version SOC Term Classification Code Term Level
    20.0 10014698 - Endocrine disorders 10000599 Acromegaly PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-000098-35 Sponsor Protocol Number: ANEPRO_2016_78 Start Date*: 2017-07-31
    Sponsor Name:SERVICIO DE ANESTESIOLOGÍA Y REANIMACIÓN HOSPITAL UNIVERSITARIO LA PAZ
    Full Title: COMPARATIVE STUDY OF NAUTICS AND VOMITING IN THREE ANESTHETICAL REGIMENS: INTRAVENOUS, INHALATORY AND MIXED.
    Medical condition: Arthroscopy for Temporomandibular
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-002742-42 Sponsor Protocol Number: 2013DM19 Start Date*: 2014-12-23
    Sponsor Name:University of Dundee/ NHS Tayside
    Full Title: Research into the Effect Of SGLT2 inhibition on left ventricular Remodelling in patients with heart failure and diabetes Mellitus
    Medical condition: Type 2 diabetes and Heart Failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-003966-42 Sponsor Protocol Number: 71691 Start Date*: 2021-02-16
    Sponsor Name:Erasmus MC
    Full Title: Adjuvant hepatic arterial infusion pump chemotherapy after repeat hepatectomy for patients with recurrent colorectal liver metastases without a history of extrahepatic disease – a phase II study
    Medical condition: LIver recurrence after hepatectomy for CRLM.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-000866-41 Sponsor Protocol Number: 2019001_mife50 Start Date*: 2021-02-02
    Sponsor Name:Women on Web International Foundation
    Full Title: Combined Phase II/ III Multicentre Single-arm Trial of a Mifepristone 50 mg as a weekly Contraceptive
    Medical condition: Prevention of unwanted pregnancy
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: Outside EU/EEA
    Trial results: (No results available)
    EudraCT Number: 2012-004863-29 Sponsor Protocol Number: 1M Start Date*: 2013-02-18
    Sponsor Name:University Hospitals Leuven (Gasthuisberg) [...]
    1. University Hospitals Leuven (Gasthuisberg)
    2. agentschap innoveren en ondernemen
    Full Title: Direct thrombin inhibitors versus low molecular weight heparins as thromboprophylaxis in Staphylococcus aureus bacteraemia. A prospective randomized controlled academic single-centre feasibility st...
    Medical condition: staphylococcus aureus bacteraemia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2006-005196-17 Sponsor Protocol Number: BCX1812-211 Start Date*: 2007-01-22
    Sponsor Name:BioCryst Pharmaceuticals, Inc.
    Full Title: A phase II, Multicenter, Randomised, Double-Mask, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Intramuscular Peramivir in Subjects with Uncomplicated Acute Influenza
    Medical condition: Uncomplicated Acute Influenza
    Disease: Version SOC Term Classification Code Term Level
    8.1 10059637 Influenza antibody test LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-001938-42 Sponsor Protocol Number: UCL-ONCO2011-01 Start Date*: 2012-01-24
    Sponsor Name:Cliniques universitaires Saint-Luc
    Full Title: Randomized Phase II Study of CABAZITAXEL versus METHOTREXATE in patients with recurrent or metastatic squamous cell carcinoma of the head and neck previously treated with platinum-based therapy
    Medical condition: To evaluate the efficacy of cabazitaxel in patients with palliative head and neck previously treated with platinum-based therapy.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2010-023461-22 Sponsor Protocol Number: ET2010-077 Start Date*: Information not available in EudraCT
    Sponsor Name:CENTRE LEON BERARD
    Full Title: Efficacité et tolérance d’emplâtres de lidocaïne à 5% (Versatis® 5%) dans les douleurs neuropathiques et dans les douleurs de crises vaso-occlusives drépanocytaires de l’enfant, de l’adolescent et ...
    Medical condition: Enfants, adolescents ou jeunes adultes présentant soit des douleurs neuropathiques pures ou mixtes soit des douleurs de crises vaso-occlusives drépanocytaires, localisées, superficielles
    Disease: Version SOC Term Classification Code Term Level
    12.1 10054095 Neuropathic pain LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: View results
    EudraCT Number: 2009-013878-40 Sponsor Protocol Number: 09.08 Start Date*: 2009-08-24
    Sponsor Name:Odense University Hospital
    Full Title: Phase II trial of Cetuximab in combination with chemotherapy (Carboplatinum and Navelbine) for patients with platinum-resistant head- and neckcancer
    Medical condition: Platinum-resistant head and neck cancer
    Disease: Version SOC Term Classification Code Term Level
    12.0 10067821 Head and neck cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2007-004232-22 Sponsor Protocol Number: SIC Start Date*: 2009-03-24
    Sponsor Name:Odense University Hospital
    Full Title: Phase II study with cetuximab, irinotecan and sunitinib (CIS) for patients with treatment resistant colorectal cancer
    Medical condition: Patients resistant to treatment of colorectal cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061451 Colorectal cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2017-001430-25 Sponsor Protocol Number: FPS-CES-2017-01 Start Date*: 2017-11-07
    Sponsor Name:Fundación Pública Andaluza Progreso y Salud
    Full Title: The effects of sufentanil or morphine added to hyperbaric bupivacaine in spinal anaesthesia for elective caesarean section.
    Medical condition: CESAREAN
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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