Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Heart surgery

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    628 result(s) found for: Heart surgery. Displaying page 3 of 32.
    « Previous 1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2010-020793-42 Sponsor Protocol Number: 170782 Start Date*: 2010-10-26
    Sponsor Name:Clinic for Thoracic and Cardiovascular Surgery, Heart Centre North Rhine-Westfalia
    Full Title: The effect of vitamin D on all-cause mortality in congestive heart failure patients
    Medical condition: Substitution of low vitamin D levels in congestive heart failure patients
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2019-001756-19 Sponsor Protocol Number: MTP-2019-01 Start Date*: 2019-12-11
    Sponsor Name:María de los Ángeles Tena Pajuelo (Investigador independiente)
    Full Title: MULTI-CENTER, DOUBLE-BLIND, CONTROLLED, PARALLEL AND RANDOMIZED STUDY TO COMPARE THE EFFECTIVENESS OF 0.1 ΜG / KG / MIN OF LEVOSIMENDAN VERSUS PLACEBO IN THE POSTOPERATIVE OF CARDIAC PROGRAMMED SUR...
    Medical condition: Patients who have preoperatively severe left ventricular dysfunction (LVEF ≤ 35%) and will be scheuled for cardiac surgery on cardiopulmonary bypass.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-001124-66 Sponsor Protocol Number: 15774603 Start Date*: 2016-07-08
    Sponsor Name:University Hospital Toulouse
    Full Title: Evaluation of the effect of double inhibition of angiotensin II AT1 receptor and neprilysin activity on sympatic nervous system activity in patient with heart failure (B2AN-SNS)
    Medical condition: Heart failure
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004849 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2005-001034-32 Sponsor Protocol Number: 05/CH/01 Start Date*: 2006-02-02
    Sponsor Name:NHS Greater Glasgow, Yorkhill
    Full Title: Does pre-operative Sildenafil protect against pulmonary related complications following cardiopulmonary bypass? A randomised trial in children undergoing cardiac surgical repair
    Medical condition: Congenital Heart Disease
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-002366-23 Sponsor Protocol Number: AD-V1-05252015 Start Date*: 2015-10-13
    Sponsor Name:Medical University of Vienna, Department of Anaesthesia, General Intensive Care and Pain Management
    Full Title: Goal-directed heart rate control during emergence from anesthesia using esmolol to attenuate myocardial injury in patients undergoing non-cardiac surgery
    Medical condition: myocardial damage
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2013-003105-25 Sponsor Protocol Number: MiLe-1 Start Date*: 2014-08-27
    Sponsor Name:Sahlgrenska University Hospital / The Queen Silvia Children´s Hospital
    Full Title: The prophylactic effect of levosimendan in reducing acute kidney injury postoperatively in pediatric patients undergoing corrective heart surgery
    Medical condition: Acute kidney injury postoperatively in connection with surgery for congenital heart disease
    Disease:
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: SE (Completed) FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004295-28 Sponsor Protocol Number: STER-AMVR-01 Start Date*: 2014-11-14
    Sponsor Name:Oulu University Hospital, Department of Anaesthesia
    Full Title: Postoperative pain management after heart valve surgery using parasternal block and PCA Oxycodone
    Medical condition: Mitral or aortic valve disease
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004865 10049495 Heart valve operation NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2015-001127-24 Sponsor Protocol Number: 290115-1 Start Date*: 2015-06-03
    Sponsor Name:Tampere Heart Hospital
    Full Title: Pharmacokinetics of enoxaparin after coronary artery bypass graft surgery
    Medical condition: Thromboprophylaxis after coronary artery bypass graft surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-006290-25 Sponsor Protocol Number: 4141 Start Date*: 2012-05-03
    Sponsor Name:Copenhagen University Hospital Rigshospitalet, The Heart Center - Department of Thoracic Surgery
    Full Title: The Pulmonary Protection Trial (PP-Trial) Pulmonary dysfunction after open heart surgery: Randomized clinical trial with focus on lung-protective interventions
    Medical condition: Dysfunction of the lungs after open heart surgery.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-003532-68 Sponsor Protocol Number: FIBCON Start Date*: 2014-03-11
    Sponsor Name:Guy's and St Thomas NHS Foundation Trust
    Full Title: Fibrinogen concentrate supplementation in the management of bleeding during paediatric cardiopulmonary bypass: a phase 1B/2A, open label dose escalation study (Version 1.0, Jan 28, 2014)
    Medical condition: Neonates and infants who are at risk of mediastinal bleeding following cardiopulmonary bypass surgery for congenital heart disease
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004849 10055817 Haemorrhage intrapericardial LLT
    16.1 100000004850 10010495 Congenital heart disease NOS LLT
    Population Age: Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-020377-16 Sponsor Protocol Number: ATIII Start Date*: 2009-11-20
    Sponsor Name:AZIENDA OSPEDALIERA OSPEDALE POLICLINICO CONSORZIALE
    Full Title: EFFECTS OF THE ADMINISTRATION OF ANTITHROMBIN ON THE EMOCOAGULATIVE STATE AND ON THE INFLAMMATORY RESPONSE IN PATIENT WITH LOW PLASMATIC LEVELS OF ANTITHROMBIN AFTER CARDIAC INTERVENTIONS
    Medical condition: Patients candidates for cardiac surgery intervention in extracorporeal circulation
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007541 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-003338-15 Sponsor Protocol Number: RBHP2014ELJEZI Start Date*: 2014-12-01
    Sponsor Name:CHU de Clermont-Ferrand
    Full Title: Role of Nitric Oxide (NO) in pre-oxygenation before anesthetic induction in patients with Pulmonary Hypertension (PH) in cardiac surgery. Feasibility study.
    Medical condition: - Cardiac surgery open heart - Pulmonary Hypertension with PAPs> 40 mmHg secondary to left heart disease or COPD (class 2 or 3), diagnosed by preoperative right heart catheterization or transthora...
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004863 10017501 Functional disturbances following cardiac surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-002233-19 Sponsor Protocol Number: ASA-CABG-01 Start Date*: 2011-10-14
    Sponsor Name:Karolinska Institute
    Full Title: Antiplatelet effects of once versus twice daily dosing of aspirin after coronary artery bypass grafting
    Medical condition: Patients having successfully undergone coronary artery bypass graft (CABG) surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2008-004626-17 Sponsor Protocol Number: 1101/08 Start Date*: 2009-03-23
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Anti-inflammatory and Anti-platelet effect of Clopidogrel and Aspirin vs Aspirin alone in Symptomatic Polyvascular disease and in patients with multiple recurrent cardiovascular events.
    Medical condition: Polyvascular disease and in patients with multiple recurrent cardiovascular events.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10032377 Other peripheral vascular disease LLT
    9.1 10028600 Myocardial ischaemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-000263-92 Sponsor Protocol Number: 17-251 Start Date*: 2018-05-28
    Sponsor Name:CHU CAEN
    Full Title: Spironolactone and perioperative atrial fibrillation occurrence in cardiac surgery patients: a multicenter randomized, double-blind study
    Medical condition: Patients > 18 years referred for elective cardiac bypass graft (CABG) surgery ± aortic valve replacement (AVR) without any systolic heart failure or any mitral surgery associated
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-005169-33 Sponsor Protocol Number: CLEAN2 Start Date*: 2018-02-23
    Sponsor Name:CHU DE POITIERS
    Full Title: An open label, multicenter, randomized trial of 2% chlorhexidine-70% isopropanol vs 5% povidone iodine-69% ethanol for skin antisepsis in reducing surgical-site infection after cardiac surgery
    Medical condition: surgery of the heart (valve, coronary or combined surgery) or of the aorta via a median sternotomy
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10048935 Open heart surgery LLT
    20.0 100000004865 10049052 Aortic surgery NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-004424-65 Sponsor Protocol Number: 15085MS-AS Start Date*: 2016-05-09
    Sponsor Name:Belfast Health and Social Care Trust
    Full Title: Prevention of post-operative complications by using HMG-CoA Reductase Inhibitor in patients undergoing oesophagectomy - A multicentre, randomised, double blind, placebo controlled trial
    Medical condition: Post-operative complications - Post-operative Pulmonary complication, Acute Respiratory Distress Syndrome and Myocardial Infarction
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2011-006241-15 Sponsor Protocol Number: GLUTAMICS2 Start Date*: 2012-02-15
    Sponsor Name:Linköping University Hospital
    Full Title: GLUTAmate for Metabolic Intervention in Coronary Surgery II
    Medical condition: Angina CCS class IV treated with coronary artery bypass surgery Coronary artery disease with moderate to severe left ventricular dysfunction treated with coronary artery bypass surgery
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10068176 Coronary artery bypass graft LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2008-006324-62 Sponsor Protocol Number: NN1810-3540 Start Date*: 2009-04-16
    Sponsor Name:Novo Nordisk A/S
    Full Title: A Multi-Centre, Randomised, Double-Blind, Placebo Controlled Trial on Efficacy and Safety of FXIII Replenishment with two different Doses of Recombinant Factor XIII following Cardiopulmonary Bypass...
    Medical condition: Aquired FXIII deficiency following cardiopulmonary bypass surgery (CABG (coronary atery bypass grafting) or CABG plus single heart valve replacement/repairs or planned replacement/repair of a singl...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10063919 Bypass surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended) DK (Completed) ES (Completed) GB (Completed) IT (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-001321-17 Sponsor Protocol Number: 11275 Start Date*: 2016-12-02
    Sponsor Name:University of Oxford
    Full Title: A randomised control trial of 5-Aminolevulinic Acid in combination with Sodium Ferrous Citrate to Enhance Cardioprotection in Adults undergoing Cardiac Surgery
    Medical condition: Low cardiac output states following cardioplegic arrest for cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004863 10007602 Cardiac and vascular procedural complications HLT
    19.0 10007541 - Cardiac disorders 10051624 Myocardial reperfusion injury PT
    19.0 10042613 - Surgical and medical procedures 10066123 Cardiopulmonary bypass PT
    19.0 10007541 - Cardiac disorders 10024920 Low output state LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    « Previous 1  2  3  4  5  6  7  8  9  Next» Last»»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Sat May 31 09:29:03 CEST 2025 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA